Screening for Structural Hemoglobin Variants in Bahia, Brazil.

Brazil was the country that received the largest number of Africans during the time of colonization, and Bahia was the Brazilian state that received the largest number of slaves from Africa. The purpose of this study was to evaluate the coverage of the newborn screening program for sickle cell disease in the Recôncavo Baiano region of the state of Bahia, and to show the frequency of the subjects with hemoglobin variants in the 2006-2009 period. Blood samples from neonates in twelve cities in the Recôncavo Baiano region were analyzed by High Performance Liquid Chromatography. A total of 16,402 children were born in this period, 14,773 of which underwent newborn screening. In this period 1416 children were born carrying hemoglobin variants HbS and HbC. Forty-seven patients--20 HbSS genotype and 27 HbSC genotype--were diagnosed in eleven of the twelve cities surveyed. The proportion of children born with sickle cell disease in the Recôncavo Baiano region was 1/314, which was higher than the 1/650 rate for the state of Bahia. The data presented in this study confirm the high frequency of sickle cell disease in Recôncavo Baiano, demonstrating the need to create a referral center for the care of patients with sickle cell diseases in the region.

[Inclusion of persons with disabilities in a Reference Center for STD / AIDS of a town in Bahia, Brazil]. / Inclusão da pessoa com deficiência em um Centro de Referência em DST/AIDS de um município baiano.

This qualitative study sought to ascertain the opinion of health professionals about the inclusion of people with disabilities in the activities of reception, prevention and treatment in a Reference Center for STD/AIDS. The data were submitted to Bardin's content analysis technique. The analysis showed that professionals conduct their service in the sense of inclusion, seeking ways of communication to reach these people as the use of LIBRAS, matching the physical structure, equality of attendance and understanding of the vulnerabilities of this population. Despite the great importance of strategies adopted in facilitating a friendly service to people with disabilities, those strategies leave mostly from isolated and individually activities. It is needed an effective link among the service managers and political actors in the construction and adaptation of materials, programs and public policies to achieve equitable and inclusion of this population.