RESUMO
The current World Health Organization classification considers the existence of an undifferentiated unclassifiable category of pleomorphic sarcomas, defined as a group of pleomorphic high-grade sarcomas. Undifferentiated high-grade pleomorphic sarcoma represents about 5% of all soft tissue sarcomas in adults and occurs more commonly in the extremities. In the oral cavity, undifferentiated pleomorphic sarcoma is extremely rare. We report a case of undifferentiated high-grade pleomorphic sarcoma located in the floor of the mouth in a man 56 years old. Microscopically, spindle-shaped cells with accented pleomorphism arranged in a storiform pattern, several bizarre giant cells, and frequent atypical mitoses were observed. The tumor cells were positive only for vimentin, with focal positivity for CD68. The patient was treated by surgery and postoperative radiation therapy, and after 25 months, no recurrence was observed.
Assuntos
Soalho Bucal/patologia , Neoplasias Bucais/patologia , Sarcoma/patologia , Antígenos CD/análise , Antígenos de Diferenciação Mielomonocítica/análise , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Soalho Bucal/cirurgia , Neoplasias Bucais/classificação , Neoplasias Bucais/terapia , Sarcoma/classificação , Sarcoma/terapia , Vimentina/análiseRESUMO
OBJECTIVE: Lipomas are relatively uncommon tumours in the oral cavity; only 1% to 4% of cases occur at this site. In this study, we describe the clinical and histopathologic features of 6 cases of oral lipoma. MATERIALS AND METHODS: Between 1997 and 2005, the files for all cases of oral lipoma at the oral pathology division, University of Ribeirão Preto, São Paulo, Brazil, were retrieved for study. Clinical data were retrieved from patient records, and all cases were reviewed microscopically and classified. RESULTS: Of the 6 cases, 3 occurred in males and 3 in females; their mean age was 50.2 years (range: 28-78 years). Most cases affected the buccal mucosa and the mean size of the tumours was 3.0 cm (range: 1.5-5.0 cm). Microscopically, 4 cases were classified as lipoma, 1 as fibrolipoma and 1 as intramuscular or infiltrative lipoma. All cases had been treated by simple surgical excision and there had been no recurrence after a mean treatment time of 50.3 months (range: 8-72 months). CONCLUSION: Oral lipomas are uncommon tumours that predominantly affect the buccal mucosa and are associated with an excellent prognosis.
