RESUMO
PURPOSE: Evaluate the efficacy and safety of intraoperative application of 5-Fluorourail in pterygium surgery and the recurrent pterigyum postoperative. MATERIALS AND METHODS: 240 eyes of 120 patients with bilateral primary pterygium were operated. One hundred twenty eyes had 5-FLU (25 mg/ml) applied intraoperatively on a sponge for five minutes. One hundred twenty contralateral eyes served as controls. RESULTS: After a follow-up of 90 days, 7 (5.83%) recurrences of the eyes which had 5-FLU applied intraoperatively were observed. In the control eyes, 25 (25.5%) recurrences were observed. Complications such as keratitis and lid edema were common in both groups. CONCLUSION: This study suggests that antifibroproliferative therapy with intraoperative sponge 5-FLU is effective and safe. Its use may be a useful adjunct in primary pterygium surgery.
Assuntos
Antifibrinolíticos/administração & dosagem , Fluoruracila/administração & dosagem , Pterígio/cirurgia , Idoso , Idoso de 80 Anos ou mais , Antifibrinolíticos/efeitos adversos , Feminino , Fluoruracila/efeitos adversos , Humanos , Cuidados Intraoperatórios , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Pterígio/tratamento farmacológico , Pterígio/prevenção & controle , Prevenção SecundáriaRESUMO
BACKGROUND: To determine the alterations in the corneal topography after pars planavitrectomy with the system of 20- and 25-gauge. METHODS: A total of 29 patients with vitreous hemorrhage. The first group (17 patients) had to undergo a pars planavitrectomy with the 20-gauge system, whereas the second (12 patients) had the pars planavitrectomy with the 25-gauge system. The corneal topography was analyzed in the pre-operation, in the first, third, and sixth months in the post-operation. RESULTS: the group which underwent the standartvitrectomy registered a statistically significant difference in the keratometric difference (dK) in the first month compared to the pre-operation (p < 0,000), first month with the third month (p < 0,020), first month and sixth month (p < 0,008). In the 25-gauge system group significant statistical alterations did not occur. CONCLUSION: astigmatism occurs in the first month post vitrectomy standard. The 25-gauge systemis notinducedastigmatism.
