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Int J Numer Method Biomed Eng ; 29(5): 601-14, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23576397

RESUMO

In this work, a computational procedure is proposed to vascularize anatomical regions supplied by many inflow sites. The proposed methodology creates a partition of the territory to be vascularized into nonoverlapping subdomains that are independently supplied by the so-called perforator arteries (inflow sites). Then, in each subdomain, the constrained constructive optimization method is used to generate a network of vessels. The identification of subdomains in a certain vascular territory perfused by many perforator arteries turns out to be a fundamental problem towards understanding the morphological conformation of peripheral beds in the cardiovascular system. The methodology is assessed through two academic examples showing the main structural features of the so-defined vascular territory partition and the corresponding arterial networks. In addition, the vascularization of a three-dimensional sheet-like tissue is presented with potential application in flap planning and design.


Assuntos
Artérias/anatomia & histologia , Hemodinâmica/fisiologia , Processamento de Imagem Assistida por Computador/métodos , Modelos Cardiovasculares , Algoritmos , Humanos , Extremidade Superior/irrigação sanguínea
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