[Eosinophilic cystopathy in association with infiltrative transitional cell carcinoma]. / Asociación de cistopatia eosinofilica con carcinoma transicional vesical infiltrante.

OBJECTIVES: To report a case of eosinophilic cystopathy associated to infiltrative transitional-cell carcino ma of the bladder in an adult. METHODS: We describe the case of a 79-year-old wo man who complains of meso and hipogastric pain since several months before, and to whom a parietal thickening of the bladder was detected by means of abdominal CT scan during the diagnostic work up for a digestive disease indicated by the Internal Medicine Service. Cistoscopy confirmed that finding, together with areas of greater endoluminal protrusion. Cold biopsy showed an inflammatory in filtrate with eosinophilic component. Transurethral resection was indicated. RESULTS: The pathological assessment was compatible with high-grade infiltrative transitional carcinoma of the bladder. The patient developed multiple lung metastases and died five months after surgery. CONCLUSIONS: Reports describing the coincidence of both entities are infrequent. We emphasize the importance of a correct filiation of apparently "pseudotumoral" endoluminallesions.

[Bladder leiomyosarcoma: case report]. / Leiomiosarcoma vesical: aportacion de un nuevo caso.

OBJECTIVES: To report a new case of bladder leiomyoma in an adult. METHODS: 64-year-old female patient consulting for a four-month hematuria diagnosed of a bladder intraluminal tumor on ultrasound during a routine gynecologic revision. Cystoscopy confirmed the presence of the tumor. Transurethral resection was indicated. RESULTS: Pathology reported a definitive diagnosis of leiomyosarcoma. Anterior pelvic exenteration was subsequently performed. On one year follow-up there is no evidence of disease. CONCLUSIONS: We emphasize the rarity of these neoplasias. We comment on their main characteristics, pointing out the importance of immunohistochemical staining for the definitive histological diagnosis. We refer the therapeutic options described in the literature.

[Infiltrative small cell carcinoma of the bladder. New case report: treatment with radical surgery and chemotherapy]. / Carcinoma vesical infiltrante de celulas pequeñas. Descripcion de un nuevo caso tratado con cirugia radical mas quimioterapia.

OBJECTIVES: To report a new case of infiltrative small cell bladder cancer. METHODS: We describe the case of a 60-year-old male patient who consulted for monosymptomatic hematuria over a few weeks. Cystoscopy showed a neoplasia in the anterior wall of the bladder. Pathological analysis of the TUR chips was compatible with infiltrative small cell tumor. After a negative staging study radical cystectomy plus adjuvant chemotherapy were indicated. RESULTS: Pathological study of the surgical specimen confirmed the diagnosis with involvement of the surrounding fat. There is no evidence of neoplasic involvement after 24 months follow-up. CONCLUSIONS: We point out the validity of a radical surgical approach for this tumor, also emphasizing the importance of adjuvant chemotherapy. We concur with other authors in the need of multicentric studies to outline the most effective surgical option, due to the limited number of cases of this entity.

[Metacronous transitional cell carcinoma of the prostatic urethra in a patient with history of nephroureterectomy for upper urinary tract urothelial tumor]. / Carcinoma transicional de uretra prostatica meta-crónico en paciente con antecedente de nefroureterectomía por tumor uroteual del tracto urinario superior.

OBJECTIVES: We report one case of Metacronous transitional cell carcinoma (TCC) of the prostatic urethra in a patient with history of left nephroureterectomy 22 years before for urothelial neoplasia of the upper urinary tract. METHODS: We describe the case of a 56-year-old male patient who presents with oligosymptomatic hematuria for several months. Cystourethroscopy showed irregular hyperemic lesions in the prostatic urethra, cold biopsy of which showed urothelial atypia. Pathology report of fragments of a posterior transurethral resection (TUR) was compatible with high-grade superficial transitional cell neoplasia. Instillation of Bacillus Calmette-Guerin (BCG) was indicated. Reevaluation TUR was performed. RESULTS: Pathologic report of new samples showed TCC infiltrating the prostatic stroma. The extension study showed ilioobturator adenopathies. Chemotherapy did not achieve significant results. Radical surgery was rejected. CONCLUSIONS: We emphasize the notable metachronous character of the transitional cell carcinoma of the prostatic urethra with respect to the upper urinary tract TCC. We also point out the metastasic capacity of these neoplasias, as well as the bad prognosis of those cases in which chemotherapy is not effective.

[Intrascrotal epidermoid inclusion cyst. Report of a new case]. / Quiste epidermoide de inclusión intraescrotal. Aportación de un nuevo caso.

OBJECTIVES: We report a new case of intra-scrotal inclusion epidermoid cyst. METHODS: We describe the case of a 47-year-old male patient who referred an increase in size of the right hemiscrotum lasting seven months. Physical examination evidenced an intra scrotal mass of elastic consistency, which was confirmed by ultrasound. Testicular tumour markers were negative. Trans-scrotal excision of the lesion was performed. RESULTS: Pathology was compatible with inclusion epidermoid cyst. The patient remains asymptomatic on follow-up visits, without evidence of lesion relapse. CONCLUSIONS: We highlight the importance of establishing a nomenclature consensus for scrotal cystic lesions. We agree with other authors on the indication of simple excision of the lesion as a treatment with intention-to-cure. However, the limited number of cases makes the long-term follow-up of these patients recommendable.