[A new syndrome: acute interstitial nephropathy with uveitis. Apropos of a case]. / Un nouveau syndrome: les néphropathies interstitielles aiguës avec uvéite. A propos d'une observation.

A 17 year old female presented with an acute interstitial nephritis and anterior uveitis. She had constitutional symptoms, a biological inflammatory syndrome, circulating immune complexes and a negative tuberculin reaction. None of the usual causes of acute interstitial nephritis and/or uveitis was found; the infectious diseases work-up was negative and the diagnosis of Behcet's syndrome and sarcoidosis were excluded. The nephritis regressed spontaneously within a few weeks; the uveitis responded to local steroids. A review of the literature revealed 26 similar cases, which suggests that this syndrome is more than a coincidental association. The kidney and the eye could be target organs of humoral and cellular immune reactions to an acute antigenic aggression; the nature of this remains unclear.

[Influence of arterial hypertension on diabetic retinopathy]. / Influence de l'hypertension artérielle sur la rétinopathie diabétique.

The influence of arterial hypertension on the prevalence of diabetic retinopathy was evaluated by a cross-sectional study in 882 diabetic patients of whom 337 were insulin-treated and 505 were non insulin-treated. Arterial hypertension was defined by blood pressure values higher than 160-90 mmHg. Retinopathy was considered to be present when at least 2 microaneurysms were observed at the posterior pole. When duration of the diabetes was taken into account the prevalence of retinopathy in hypertensive subjects (69%) was not significantly higher than in normotensive subjects (47%) among the insulin-treated patients. However among non insulin-treated patients retinopathy was significantly more frequent in hypertensive (39%), than in normotensive subjects (25%; p less than 0.05).

[Hypoplasia of the optic nerve head]. / Hypoplasie de la tête du nerf optique.

Optic nerve hypoplasia is not a rare eventuality in children. This report discusses the clinical features of 10 new cases on a multiple point of view including optic canal tomography, fluorescein angiography and cat's examination. Optic nerve hypoplasia is not always accompanied by decreased visual acuity: sector fields are often identified in these cases.