1.
Arch Exp Veterinarmed
; 43(2): 249-53, 1989 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2774822
RESUMO
The present study aimed at exploring the effect of antihistamine chloropheniramine maleate (H1-blocker) on liver and kidney functions as well as on blood count. 60 mature guinea pigs were used. Histamine or chloropheniramine maleate was given, either alone or together, intramuscularly for 7 successive days. At the end of the experimental period, blood samples were collected for determination of blood counts and of the levels of urea, creatinine, GOT, GPT, and alkaline phosphatase in the sera of different groups. The results showed significant groupwise variations in blood count, liver function as well as kidney function.
Assuntos
Clorfeniramina/toxicidade , Cobaias/fisiologia , Rim/efeitos dos fármacos , Fígado/efeitos dos fármacos , Animais , Contagem de Células Sanguíneas/veterinária , Cobaias/sangue
2.
Arch Exp Veterinarmed
; 42(6): 848-53, 1988 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3219028