The serological response to foot-and-mouth disease vaccination is not affected by simultaneous infectious bovine rhinotracheitis/adenovirus/parainfluenza 3 vaccination.

Young calves were simultaneously vaccinated by subcutaneous route against foot-and-mouth disease (FMD) and against infectious bovine rhinotracheitis/adenovirus/parainfluenza-3 (IBR/Adeno/PI-3) by intranasal route. The serological response against the 3 FMD virus types of the FMD vaccine was clearly positive. There was no significant difference between results of simultaneous FMD and IBR/Adeno/PI-3 vaccination and FMD vaccination only.

[Research on antibodies against BHV-1, BHV-2, BHV-4, BVD-MD virus, bovine adenovirus A and B, rotavirus and coronavirus in cattle in western Zaire: complementary results]. / Recherche des anticorps dirigés contre les BHV-1, BHV-2, BHV-4, le virus BVD-MD, les adénovirus A et B, le rotavirus et le coronavirus bovins chez des bovins de l'Ouest du Zaïre: résultats complémentaires.

Two-hundred bovine sera from western Zaire were screened for antibodies to 8 viruses: BHV-1, BHV-2, BHV-4, BVD-MD virus, bovine adenovirus A and B, bovine rotavirus and bovine coronavirus. Positive sera were found to all these viruses. For animals whose origin was undoubted, the main features were the high prevalence of infections by rotavirus and BHV-4 and the low prevalence of infections by coronavirus and BVD-MD virus.

BHV4 (bovine herpes virus 4) related disorders in Belgian cattle: a study of two problem herds.

Two cattle farms, with a ten year history of BHV4 related postpartum metritis accompanied by fertility problems, were monitored during the winter season 1985-1986. BHV4 was isolated from the lochia from 55% of the animals on farm A and 66% of those on farm B. Respectively 59% and 30% of the animals presented postpartum metritis. In some animals virus multiplication was followed by severe leucopenia lasting several weeks. Indirect immunofluorescence (IIF) BHV4 seropositive as well as IIF seronegative animals were affected. The latter responded with a rapid or late IIF antibody reaction. No BHV4 seroneutralizing antibodies could be detected. The authors also suggest a possible role of BHV4 in the respiratory problems observed during the study.

[Demonstration of BVD virus (bovine diarrhea virus) in many cell lines]. / Mise en évidence du virus BVD (bovine viral diarrhoea virus) dans plusieurs lignées cellulaires.

By specific fluorescent antibodies, it was shown that cell lines from bovine origin were contaminated with BVD virus. The same virus was also detected in cell lines from different species like horse, cat, monkey, rabbit, pig and sheep. The authors express their concern about the use of these cell lines as substrate for live virus vaccines.

[Experimental inoculation of bovine herpesvirus 4 (strain LVR 140) in pregnant and nonpregnant cows]. / Inoculation expérimentale du virus LVR 140 (herpès bovin IV) à des vaches gestantes et non-gestantes.

Ten cows (5 pregnant and 5 non pregnant) were inoculated with a BHV 4 (Bovine Herpes Virus 4) strain LVR 140. The infection caused metritis symptoms, but only after parturition and even if the calving occurred several weeks after the inoculation. The metritis was accompanied by leucopenia. The virus was reisolated from the lochia and the lymph nodes, in some cases several weeks after parturition. A number of unexplained mortalities was observed during the experiment. The evolution of antibodies detected by the indirect immunofluorescence test (IIF) showed two levels: the first after inoculation and the second after parturition.