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1.
Colorectal Dis ; 26(6): 1258-1265, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38807266

RESUMO

AIM: Most new ostomy patients are not able to manage ostomy self-care when they are discharged and rely on visiting nurse services for ostomy care. The aim of this study was to determine if a perioperative ostomy educational pathway increases the level of independence and decreases the need for visiting nurse services in new ostomy patients. METHOD: A prospective longitudinal study was conducted between July 2018 and February 2020. Patients who received a colostomy or ileostomy and were treated on the surgery ward were included. Patients who followed a perioperative ostomy educational pathway were compared to a historical control group. The primary outcome measure was the level of independence in ostomy care and the need for visiting nurse services. RESULTS: After discharge, 67.6% of patients in the intervention group (n = 244) were able to independently perform ostomy care and were therefore not relying on visiting nurse services, compared to 15.2% of the patients in the control group (n = 33). The need for visiting nurse services was higher in patients aged ≥70 years (OR 3.20, P < 0.001), those who did not attend the preoperative practice session (OR 3.02, P = 0.002), those with a history of transient ischaemic attack (OR 10.22, P = 0.045) and those with mild cognitive impairment (OR 28.98, P = 0.002). CONCLUSION: A perioperative ostomy educational pathway effectively increased the level of independence and decreased the need for visiting nurse services in new ostomy patients.


Assuntos
Ileostomia , Educação de Pacientes como Assunto , Autocuidado , Humanos , Feminino , Masculino , Idoso , Estudos Prospectivos , Estudos Longitudinais , Pessoa de Meia-Idade , Ileostomia/enfermagem , Educação de Pacientes como Assunto/métodos , Colostomia/enfermagem , Enfermagem em Saúde Comunitária , Assistência Perioperatória/métodos , Idoso de 80 Anos ou mais , Alta do Paciente , Estomia/enfermagem
2.
Int J Mol Sci ; 20(9)2019 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-31072023

RESUMO

Consumption of nitrate-rich beetroot juice (BRJ) by athletes induces a number of beneficial physiological health effects, which are linked to the formation of nitric oxide (NO) from nitrate. However, following a secondary pathway, NO may also lead to the formation of N-nitroso compounds (NOCs), which are known to be carcinogenic in 39 animal species. The extent of the formation of NOCs is modulated by various other dietary factors, such as vitamin C. The present study investigates the endogenous formation of NOCs after BRJ intake and the impact of vitamin C on urinary NOC excretion. In a randomized, controlled trial, 29 healthy recreationally active volunteers ingested BRJ with or without additional vitamin C supplements for one week. A significant increase of urinary apparent total N-nitroso Compounds (ATNC) was found after one dose (5 to 47 nmol/mmol: p < 0.0001) and a further increase was found after seven consecutive doses of BRJ (104 nmol/mmol: p < 0.0001). Vitamin C supplementation inhibited ATNC increase after one dose (16 compared to 72 nmol/mmol, p < 0.01), but not after seven daily doses. This is the first study that shows that BRJ supplementation leads to an increase in formation of potentially carcinogenic NOCs. In order to protect athlete's health, it is therefore important to be cautious with chronic use of BRJ to enhance sports performances.


Assuntos
Antioxidantes/administração & dosagem , Desempenho Atlético , Beta vulgaris/química , Nitratos/administração & dosagem , Adolescente , Adulto , Antioxidantes/química , Ácido Ascórbico/administração & dosagem , Ácido Ascórbico/urina , Suplementos Nutricionais , Feminino , Sucos de Frutas e Vegetais , Humanos , Masculino , Pessoa de Meia-Idade , Nitratos/química , Nitratos/urina , Nitritos/urina , Compostos Nitrosos/urina , Raízes de Plantas/química , Adulto Jovem
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