Assessment of decompressive surgery in dogs with degenerative lumbosacral stenosis using force plate analysis and questionnaires.

OBJECTIVE: To evaluate the long-term outcome after decompressive surgery in dogs with degenerative lumbosacral stenosis (DLS), using force plate analysis (FPA) and owner questionnaires. STUDY DESIGN: Prospective clinical study. ANIMALS: Dogs with DLS (n=31) and 24 clinically normal Labrador Retrievers. METHODS: FPA was performed before surgery (31 dogs) and at 3 days, 6 weeks, 6 months (each, 31 dogs) and >or=1.5 years (12 dogs) after surgery. Peak vertical forces (Fz(+)), braking (Fy(+)), and propulsive forces (Fy(-)), and the corresponding impulses were determined. Questionnaires were completed by the owners before and at 6 months and >or=1.5 years after surgery. RESULTS: Fy(-) of the pelvic limbs and the ratio pelvic/thoracic of Fy(-) (P/TFy(-)) were significantly smaller in dogs with DLS than controls. Fy(-) and P/TFy(-) decreased significantly 3 days after surgery, and increased during 6 months follow-up, but with long-term follow-up the values remained the same and were smaller than controls. From questionnaires there was a significant improvement after surgery compared with function before surgery. Most owners were satisfied with outcome after surgery. CONCLUSIONS: Propulsive forces of the pelvic limbs in dogs with DLS are impaired and are partially restored by decompressive surgery. CLINICAL RELEVANCE: Owner's questionnaires illustrate that decompressive surgery restores function as perceived by owners whereas FPA continues to show impaired propulsive forces for the pelvic limbs.

Hepatic (64)Cu excretion in Dobermanns with subclinical hepatitis.

To investigate whether Dobermanns have impaired copper excretion an intravenous radioactive copper isotope ((64)Cu) was used as a tracer. Five patients and eight normal dogs (5 normal Dobermanns and 3 Beagles) were studied. The five female Dobermann patients had a subclinical hepatitis and an increased hepatic copper concentration (median 822mg/kg, range 690-1380mg/kg dry matter). The normal dogs, five Dobermanns and three Beagles, had no abnormal liver histopathology and hepatic copper concentrations were considered normal (Dobermanns; median 118mg/kg, range 50-242mg/kg dry matter; Beagles; median 82mg/kg, range 50-88mg/kg dry matter). Cholestasis was excluded in all dogs by means of a (99m)Tc-Bis-IDA hepatobiliary scintigraphy. Plasma clearance of (64)Cu was comparable in all dogs with no statistically significant differences. The excretion of (64)Cu into the bile, although not statistically significant, was less for the Dobermanns with subclinical hepatitis compared to the normal dogs. The findings suggest that impaired copper excretion may play a role in the aetiology of chronic hepatitis in the Dobermann.