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1.
Sensors (Basel) ; 24(3)2024 02 02.
Artigo em Inglês | MEDLINE | ID: mdl-38339703

RESUMO

Blockchain's potential to revolutionize supply chain and logistics with transparency and equitable stakeholder engagement is significant. However, challenges like scalability, privacy, and interoperability persist. This study explores the scarcity of real-world blockchain implementations in supply chain and logistics since we have not witnessed many real-world deployments of blockchain-based solutions in the field. Puzzled by this, we integrate technology, user experience, and operational efficiency to illuminate the complex landscape of blockchain integration. We present blockchain-based solutions in three use cases, comparing them with alternative designs and analyzing them in terms of technical, economic, and operational aspects. Insights from a tailored questionnaire of 50 questions addressed to practitioners and experts offer crucial perspectives on blockchain adoption. One of the key findings from our work shows that half of the companies interviewed agree that they will miss the potential for competitive advantage if they do not invest in blockchain technology, and 61% of the companies surveyed claimed that their customers ask for more transparency in supply chain-related transactions. However, only one-third of the companies were aware of the main features of blockchain technology, which shows a lack of knowledge among the companies that may lead to a weaker blockchain adaption in supply chain use cases. Our readers should note that our study is specifically contextualized in a Netherlands-funded national project. We hope that researchers as well as stakeholders in supply chain and logistics can benefit from the insights of our work.


Assuntos
Blockchain , Medo , Conscientização , Conhecimento , Países Baixos
2.
Acta Orthop ; 93: 451-458, 2022 04 28.
Artigo em Inglês | MEDLINE | ID: mdl-35485295

RESUMO

BACKGROUND AND PURPOSE: Ceramic liners may reduce early stability of uncemented acetabular components due to higher stiffness. However, the bone ingrowth capacities of porous trabecular titanium might compensate for this effect. This prospective randomized trial quantifies migration patterns of the Delta-TT cup, and compares polyethylene and ceramic liners. PATIENTS AND METHODS: Patients undergoing primary uncemented total hip arthroplasty with the Delta-TT cup and femoral stem with ceramic head were randomized to a polyethylene (n = 25) or ceramic (n = 28) liner. Radiostereometric analysis (RSA) radiographs, patient-reported hip function (HOOS-PS, OHS), and quality of life (EQ5D) were collected at baseline and 1.5, 3, 6, 12, and 24 months postoperatively. Model-based RSA was used to calculate 3D cup translation and rotation, and mixed models were used to compare effects over time between groups. RESULTS: At 2 years follow-up, Delta-TT cups showed similar mean proximal translation of 0.56 mm (95% CI 0.38-0.75) in the ceramic (CE) group and 0.54 mm (0.30-0.77) in the polyethylene (PE) group, with a between group effect of 0.02 mm (-0.20-0.23). Most cup migration occurred in the first 1.5 to 3 months, stabilizing within 6 months. Any between-group effects were ≤ 0.30 mm for translation and ≤ 0.45° for rotation. Improvements in patient-reported hip function and quality of life were similar in both groups. INTERPRETATION: Regardless of liner type, Delta-TT cups showed some initial migration and stabilized within 6 months, which seems promising for long-term fixation in both cup-liner constructs.


Assuntos
Artroplastia de Quadril , Prótese de Quadril , Artroplastia de Quadril/efeitos adversos , Cerâmica , Humanos , Polietileno , Estudos Prospectivos , Desenho de Prótese , Falha de Prótese , Qualidade de Vida , Análise Radioestereométrica , Titânio
3.
Knee Surg Sports Traumatol Arthrosc ; 27(12): 3929-3936, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31123795

RESUMO

PURPOSE: The aim of the present study was to determine the long-term outcome after the arthroscopic Bankart procedure, in terms of recurrent instability, shoulder function, glenohumeral arthropathy and patient satisfaction. METHODS: Patients who underwent the arthroscopic Bankart procedure between January 1999 and the end of December 2005 were invited to complete a set of Patient Reported Outcome Measures (PROMs) and visit the hospital for clinical and radiological assessment. PROMs included the Western Ontario Shoulder Instability Index (WOSI), the Oxford Shoulder Instability Score (OSIS) and additional questions on shoulder instability and patient satisfaction. Clinical assessment included the apprehension test and the Constant-Murley score. The Samilson-Prieto classification was used to assess arthropathy on standard radiographs. The primary outcome was a re-dislocation that needed reduction. Secondary outcomes in terms of recurrent instability included patient-reported subluxation and a positive apprehension test. RESULTS: Of 104 consecutive patients, 71 patients with a mean follow-up of 13.1 years completed the PROMs, of which 53 patients (55 shoulders) were also available for clinical and radiological assessment. Re-dislocations had occurred in 7 shoulders (9.6%). Subluxations occurred in 23 patients (31.5%) and the apprehension test was positive in 30 (54.5%) of the 55 shoulders examined. Median functional outcomes were 236 for WOSI, 45 for OSIS, and 103 for the normalized Constant-Murley score. Of all 71 patients (73 shoulders), 29 (39.7%) reported being completely satisfied, 33 (45.2%) reported being mostly satisfied and 8 (11%) reported being somewhat satisfied. Glenohumeral arthropathy was observed in 33 (60%) of the shoulders. CONCLUSION: Despite 10% re-dislocations and frequent other signs of recurrent instability, shoulder function and patient satisfaction at 13 years after arthroscopic Bankart repair were good. LEVEL OF EVIDENCE: Level IV.


Assuntos
Artroscopia/métodos , Recidiva , Luxação do Ombro/cirurgia , Adolescente , Adulto , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Medidas de Resultados Relatados pelo Paciente , Satisfação do Paciente , Estudos Retrospectivos
4.
J Med Primatol ; 46(5): 263-266, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28523858

RESUMO

A chimpanzee (Pan troglodytes) was presented with lethargic behaviour. Echocardiography and abnormal cardiac and inflammatory biomarkers revealed a myocarditis. The animal fully recovered after prolonged treatment with losartan and carvedilol. This is the first report of the diagnosis and successful treatment of myocarditis in this species.


Assuntos
Antagonistas Adrenérgicos beta/uso terapêutico , Antiarrítmicos/uso terapêutico , Doenças dos Símios Antropoides/diagnóstico , Doenças dos Símios Antropoides/tratamento farmacológico , Miocardite/veterinária , Animais , Carbazóis/uso terapêutico , Carvedilol , Feminino , Losartan/uso terapêutico , Miocardite/diagnóstico , Miocardite/tratamento farmacológico , Pan troglodytes , Propanolaminas/uso terapêutico , Resultado do Tratamento
5.
Skeletal Radiol ; 43(4): 475-83, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24442561

RESUMO

OBJECTIVE: The purpose of this study is to investigate if magnetic resonance imaging with intra-articular contrast (MR-arthro) is as reliable as three-dimensionally reconstructed computed tomography imaging (3D-CT) in quantifying the glenoid bone loss in patients with anterior shoulder instability. MATERIALS AND METHODS: Thirty-five patients were included. Sagittal MR-arthro and 3D-CT images of the glenoid surface were obtained pre-operatively. Two observers measured these images twice with OsiriX software in a randomized and blinded way. The intraclass correlations (ICC) of the intra- and inter-observer reliability within one method and an additional Bland-Altman plot for calculating agreement between the two methods were obtained. RESULTS: The joint estimates of the intra-observer reliability, taking into account the data from both observer A and B, for 3D-CT and MR-arthro were good to excellent. The intra-observer reliability was 0.938 (95% CI: 0.879, 0.968) for 3D-CT and 0.799 (95% CI: 0.639, 0.837) for MR-arthro. The inter-observer reliability between the two observers within one method (3D-CT or MR-arthro) was moderate to good. 3D-CT: 0.724 (95% CI: 0.236, 0.886) and MR-arthro: 0.534 (95% CI: 0.128, 0.762). Comparing both the 3D-CT and MR-arthro method, a Bland-Altman plot showed satisfying differences with the majority of outcomes (89%) within 1 SD. CONCLUSIONS: Good to excellent intra- and moderate to good inter-observer correlations and a satisfying Bland-Altman plot when compared to 3D-CT show tendencies that MR-arthro is reliable and valid for measuring bony defects of the glenoid.


Assuntos
Cavidade Glenoide/diagnóstico por imagem , Cavidade Glenoide/patologia , Instabilidade Articular/diagnóstico , Imageamento por Ressonância Magnética/métodos , Osteólise/diagnóstico , Tomografia Computadorizada por Raios X/métodos , Adolescente , Adulto , Feminino , Humanos , Interpretação de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Instabilidade Articular/complicações , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Osteólise/etiologia , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Adulto Jovem
6.
Congenit Heart Dis ; 8(6): 576-8, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-21718457

RESUMO

We present a case of L-1 type solitary (left) coronary artery that was detected with coronary computed tomography angiography and confirmed by invasive coronary angiography in a female patient with atypical chest pain. Solitary coronary artery anomalies are rare. The L-1 subtype is thought to be a benign type.


Assuntos
Angiografia Coronária/métodos , Anomalias dos Vasos Coronários/diagnóstico por imagem , Vasos Coronários/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Angina Pectoris/etiologia , Anomalias dos Vasos Coronários/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Valor Preditivo dos Testes
7.
Skeletal Radiol ; 38(7): 675-83, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19421749

RESUMO

PURPOSE: The purpose of this study is to retrospectively compare accuracy of single magnetic resonance (MR) arthrography series in Abduction External Rotation (ABER) with conventional MR arthrography for detection and characterisation of anteroinferior labroligamentous lesions, with arthroscopy as reference standard. Inter-observer variability of both protocols was determined. METHODS AND MATERIALS: Institutional review board approval was obtained; informed consent was waived. MR arthrograms, including oblique axial fat suppressed T1-weighted images in ABER position and conventional imaging directions of 250 patients (170 men, 80 women; mean age, 36 years), were retrospectively and independently evaluated by three reviewers. Reviewers were blinded to clinical information and arthroscopic results. Labroligamentous lesions were registered in both ABER and MRa. The lesions were sub-classified (Bankart, Perthes, anterior labrum periosteal sleeve avulsion (ALPSA) or lesions not otherwise specified). Inter-observer agreement was assessed by Kappa statistics for all 250 patients. Ninety-two of 250 patients underwent arthroscopy. Sensitivity, specificity and accuracy of ABER versus conventional MR arthrography were calculated and compared using paired McNemar test. RESULTS: Kappa values of the ABER and conventional MR arthrography ranged from 0.44 to 0.56 and 0.44 to 0.62, respectively. According to arthroscopy, 45 of 92 patients had an intact anteroinferior labrum, and in 44 patients, a labroligamentous lesion (eight Bankart, seven Perthes, 29 ALPSA and three lesions not otherwise specified) was diagnosed. There were no statistically significant differences between ABER and conventional MR arthrography regarding sensitivity (85-89%, 89-96%), specificity (82-91%, 84-89%) and overall accuracy (50-62%, 53-63%). CONCLUSION: The results of a single MR arthrography series in ABER position are comparable with those of conventional MR arthrography for detecting anteroinferior labroligamentous lesions.


Assuntos
Artrografia/métodos , Ligamentos Articulares/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Articulação do Ombro/diagnóstico por imagem , Adulto , Feminino , Humanos , Masculino , Variações Dependentes do Observador , Estudos Retrospectivos , Sensibilidade e Especificidade
8.
Skeletal Radiol ; 38(10): 967-75, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19294377

RESUMO

PURPOSE: The purpose of this study was to retrospectively evaluate sensitivity and specificity of a single magnetic resonance (MR) arthrography series in abduction external rotation (ABER) position compared with conventional MR arthrography for detection of supraspinatus tendon tears, with arthroscopy as gold standard, and to assess interobserver variability. MATERIALS AND METHODS: Institutional review board approval was obtained; informed consent was waived. MR arthrograms of 250 patients (170 men and 80 women; mean age, 36 years) were retrospectively and independently evaluated by three observers. Oblique coronal T1-weighted fat-suppressed images, proton density, and T2-weighted images and axial T1-weighted images and oblique sagittal T1-weighted fat-suppressed images were analyzed to detect supraspinatus tendon tears. Separately, a single T1-weighted fat-suppressed oblique axial series in ABER position was evaluated. Both protocols were scored randomly without knowledge of patients' clinical history and arthroscopy results. Tears were subclassified, based on articular surface integrity and extension (Lee classification). Interobserver agreement was assessed by kappa statistics for all patients. Ninety-two of 250 patients underwent arthroscopy; sensitivity and specificity of ABER and conventional MR arthrography were calculated and compared using paired McNemar test. RESULTS: Weighted kappa values of ABER and conventional MR arthrography were 0.48-0.65 and 0.60-0.67, respectively. According to arthroscopy, 69 of 92 patients had an intact cuff, and 23 patients had a cuff tear (16 partial thickness and seven full thickness). There were no statistically significant differences between ABER and conventional MR arthrography regarding sensitivity (48-61% and 52-70%, respectively) and specificity (80-94% and 91-95%). CONCLUSION: Sensitivity and specificity of a single T1-weighted series in ABER position and conventional MR arthrography are comparable for assessment of rotator cuff tears.


Assuntos
Aumento da Imagem/métodos , Imageamento por Ressonância Magnética/métodos , Postura , Lesões do Ombro , Ombro/patologia , Traumatismos dos Tendões/diagnóstico , Adulto , Artrografia/métodos , Feminino , Humanos , Masculino , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
9.
Int Urogynecol J Pelvic Floor Dysfunct ; 19(9): 1291-7, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18465077

RESUMO

To estimate the accuracy of clinical examination and the indications for defecography in patients with primary posterior wall prolapse. Fifty-nine patients with primary pelvic organ prolapse were evaluated with a questionnaire, clinical examination and defecography. Defecography was used as reference standard. There was no relation between bowel complaints and posterior wall prolapse evaluated by clinical examination (p = 0.33), nor between bowel complaints and rectocele (p = 0.19) or enterocele (p = 0.99) assessed by defecography. The diagnostic accuracy of clinical examination in diagnosing rectocele was 0.42, sensitivity was 1.0 and specificity was 0.23. The diagnostic accuracy of clinical examination in diagnosing enterocele was 0.73, with a sensitivity of 0.07 and a specificity of 0.95. Clinical examination is not accurate to assess anatomic defects of the posterior vaginal wall. Defecography is recommended as a helpful diagnostic tool in the work-up of patients with posterior vaginal wall prolapse if surgical repair is considered.


Assuntos
Defecografia , Prolapso Uterino/diagnóstico , Vagina/diagnóstico por imagem , Feminino , Humanos , Pessoa de Meia-Idade , Exame Físico , Valor Preditivo dos Testes , Sensibilidade e Especificidade , Estatísticas não Paramétricas , Inquéritos e Questionários , Prolapso Uterino/diagnóstico por imagem
10.
J Shoulder Elbow Surg ; 16(6): 803-9, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18061117

RESUMO

Bone loss of the glenoid is a common finding in anterior glenohumeral instability. Several methods to measure the size of a glenoid defect have been described but have not been validated. In this study, 14 cadaver glenoids with a randomly created anteroinferior glenoid defect were used for validation of the so-called circle method. Measurements were done by 2 researchers on digital photographs, 3-dimensional (3D) computed tomography (CT) scans, and magnetic resonance images (MRI). The correlation coefficient (r(2)) for comparing measurements from the digital photographs with the CT scans was 0.97 for researcher 1 and 0.90 for researcher 2. When they compared digital images with MRI, the r(2) was 0.93 for researcher 1 and 0.92 for researcher 2. No statistical differences were found between the 2 researchers. The circle method is a simple method for preoperative quantification of a glenoid defect. Measurements can be done with 3D CT scans as well as MRI.


Assuntos
Instabilidade Articular/complicações , Imageamento por Ressonância Magnética , Articulação do Ombro/diagnóstico por imagem , Articulação do Ombro/patologia , Tomografia Computadorizada por Raios X , Doenças Ósseas/diagnóstico por imagem , Doenças Ósseas/etiologia , Doenças Ósseas/patologia , Cadáver , Humanos , Imageamento Tridimensional , Instabilidade Articular/diagnóstico por imagem , Instabilidade Articular/patologia
11.
Radiology ; 245(1): 150-9, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17885188

RESUMO

PURPOSE: To prospectively evaluate participants' experience and preference of magnetic resonance (MR) colonography with limited bowel preparation compared with full-preparation colonoscopy in participants at increased risk for colorectal cancer. MATERIALS AND METHODS: This study had institutional review board approval; all participants gave written informed consent. In this multicenter study, consecutive participants undergoing conventional colonoscopy because of a personal or family history of colorectal cancer or adenomatous polyps underwent MR colonography 2 weeks prior to colonoscopy. They all followed a low-fiber diet and were given lactulose and an oral contrast agent (fecal tagging with gadolinium) 2 days before colonography. Before imaging, spasmolytics were administered intravenously, and a water-gadolinium chelate mixture was administered rectally for distention of the colon. Breath-hold T1- and T2-weighted sequences were performed in the prone and supine positions. Participant experience in terms of, for example, pain and burden was determined by using a five-point scale and was evaluated with a Wilcoxon signed rank test; participant preference was determined by using a seven-point scale and was evaluated with the chi2 statistic after dichotomizing. RESULTS: Two hundred nine participants (77 women, 132 men; mean age, 58 years; range, 23-84 years) were included. One hundred forty-eight participants received sedatives (midazolam) and/or analgesics (fentanyl) during colonoscopy. Participants rated the MR colonography bowel preparation as less burdensome (P<.001) compared with the colonoscopy bowel preparation (10% and 71% of participants rated the respective examinations moderately to extremely burdensome). Participants also experienced less pain at MR colonography (P<.001) and found MR colonography less burdensome (P<.001). Immediately after both examinations, 69% of participants preferred MR colonography, 22% preferred colonoscopy, and 9% were indifferent (P<.001, 69% vs 22%). After 5 weeks, 65% preferred MR colonography and 26% preferred colonoscopy (P<.001). CONCLUSION: Participants preferred MR colonography without extensive cleansing to colonoscopy immediately after both examinations and 5 weeks later. Experience of the bowel preparation and of the procedure was rated better.


Assuntos
Colonoscopia , Fármacos Gastrointestinais/farmacologia , Imageamento por Ressonância Magnética/métodos , Aceitação pelo Paciente de Cuidados de Saúde , Pólipos Adenomatosos/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Catárticos/administração & dosagem , Neoplasias Colorretais/diagnóstico , Feminino , Gadolínio , Humanos , Lactulose/farmacologia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Inquéritos e Questionários
12.
Eur Radiol ; 17(12): 3112-22, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17549490

RESUMO

The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose and amidotrizoic-acid for fecal tagging 2 days prior to the CT scan (standard dose, 5.8-8.2 mSv). The original raw data of 51 patients were modified and reconstructed at simulated 2.3 and 0.7 mSv levels. Two observers evaluated the standard dose scan regarding image quality and polyps. A third evaluated the presence of polyps at all three mSv levels in a blinded prospective way. All observers were blinded to the reference standard: colonoscopy. At three times patients were given questionnaires relating to their experiences and preference. Image quality was sufficient in all patients, but significantly lower in the cecum, sigmoid and rectum. The two observers correctly identified respectively 10/15 (67%) and 9/15 (60%) polyps > or =10 mm, with 5 and 8 false-positive lesions (standard dose scan). Dose reduction down to 0.7 mSv was not associated with significant changes in diagnostic value (polyps > or =10 mm). Eighty percent of patients preferred CT colonography and 13% preferred colonoscopy (P<0.001). CT colonography without cleansing is preferred to colonoscopy and shows sufficient image quality and moderate sensitivity, without impaired diagnostic value at dose-levels as low as 0.7 mSv.


Assuntos
Colonografia Tomográfica Computadorizada/métodos , Pólipos Intestinais/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Catárticos/administração & dosagem , Distribuição de Qui-Quadrado , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Aceitação pelo Paciente de Cuidados de Saúde , Estudos Prospectivos , Doses de Radiação , Análise de Regressão , Estatísticas não Paramétricas , Inquéritos e Questionários
13.
Radiology ; 243(1): 122-31, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17329686

RESUMO

PURPOSE: To prospectively evaluate the diagnostic performance of magnetic resonance (MR) colonography by using limited bowel preparation in patients with polyps of 10 mm or larger in diameter in a population at increased risk for colorectal cancer, with optical colonoscopy as the reference standard. MATERIALS AND METHODS: The institutional review boards of all three hospitals approved the study. All patients provided written informed consent. In this multicenter study, patients undergoing colonoscopy because of a personal or family history of colorectal cancer or adenomatous polyps were included. Two blinded observers independently evaluated T1- and T2-weighted MR colonographic images obtained with limited bowel preparation (bright-lumen fecal tagging) for the presence of polyps. The limited bowel preparation consisted of a low-fiber diet, with ingestion of lactulose and an oral gadolinium-based contrast agent (with all three major meals) starting 48 hours prior to imaging. Results were verified with colonoscopic outcomes. Patient sensitivity, patient specificity, polyp sensitivity, and interobserver agreement for lesions of 10 mm or larger were calculated for both observers individually and combined. RESULTS: Two hundred patients (mean age, 58 years; 128 male patients) were included; 41 patients had coexistent symptoms. At colonoscopy, 12 patients had 22 polyps of 10 mm or larger. Per-patient sensitivity was 58% (seven of 12) for observer 1, 67% (eight of 12) for observer 2, and 75% (nine of 12) for both observers combined for polyps of 10 mm or larger. Per-patient specificity was 95% (178 of 188) for observer 1, 97% (183 of 188) for observer 2, and 93% (175 of 188) for both observers combined. Per-polyp sensitivity was 55% (12 of 22) for observer 1, 50% (11 of 22) for observer 2, and 77% (17 of 22) for both observers combined. Interobserver agreement was 93% for identification of patients with lesions of 10 mm or larger. CONCLUSION: In patients at increased risk for colorectal cancer, specificity of MR colonography by using limited bowel preparation was high, but sensitivity was modest.


Assuntos
Pólipos do Colo/diagnóstico , Neoplasias Colorretais/diagnóstico , Imageamento por Ressonância Magnética , Adulto , Idoso , Idoso de 80 Anos ou mais , Colonoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Pré-Operatórios , Estudos Prospectivos , Sensibilidade e Especificidade
14.
AJR Am J Roentgenol ; 187(4): 991-9, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16985148

RESUMO

OBJECTIVE: External anal sphincter atrophy seen at endoanal MRI may predict poor outcome of surgical anal sphincter repair for an external anal sphincter defect. The purposes of this study were to compare external phased-array MRI to endoanal MRI for depicting external anal sphincter atrophy in patients with fecal incontinence and to evaluate observer reproducibility in detecting external anal sphincter atrophy with these techniques. SUBJECTS AND METHODS: Thirty patients with fecal incontinence (23 women, seven men; mean age, 58.7 years; age range, 37-78 years) underwent both endoanal and external phased-array MRI. Images were evaluated for external anal sphincter atrophy by three radiologists. Measures of differences and agreement between both MRI techniques and of interobserver and intraobserver agreement of both techniques were calculated. RESULTS: The MRI techniques did not significantly differ in their ability to depict external anal sphincter atrophy (p = 0.63) with good agreement (kappa = 0.72). Interobserver agreement was moderate (kappa = 0.53-0.56) for endoanal MRI and moderate to good (kappa = 0.55-0.8) for external phased-array MRI. Intraobserver agreement was moderate to very good (kappa = 0.57-0.86) for endoanal MRI and fair to very good (kappa = 0.31-0.86) for external phased-array MRI. CONCLUSION: External phased-array MRI is comparable to endoanal MRI in depicting external anal sphincter atrophy and, thereby, in selecting patients for anal sphincter repair. Because results among interpreters varied considerably depending on the experience level, both techniques can be recommended in the diagnostic workup of fecal incontinence only if sufficient experience is available.


Assuntos
Canal Anal/patologia , Incontinência Fecal/diagnóstico , Imageamento por Ressonância Magnética , Adulto , Idoso , Canal Anal/inervação , Atrofia , Incontinência Fecal/patologia , Incontinência Fecal/fisiopatologia , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Condução Nervosa , Variações Dependentes do Observador , Reprodutibilidade dos Testes
15.
Eur Radiol ; 16(8): 1745-9, 2006 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16636802

RESUMO

Our purpose was to assess the effect of reader experience, fatigue, and scan findings on interpretation time for CT colonography. Nine radiologists (experienced in CT colonography); nine radiologists and ten technicians (both groups trained using 50 validated examinations) read 40 cases (50% abnormal) under controlled conditions. Individual interpretation times for each case were recorded, and differences between groups determined. Multi-level linear regression was used to investigate effect of scan category (normal or abnormal) and observer fatigue on interpretation times. Experienced radiologists (mean time 10.9 min, SD 5.2) reported significantly faster than less experienced radiologists and technicians; odds ratios of reporting times 1.4 (CI 1.1, 1.8) and 1.6 (1.3, 2.0), respectively (P

Assuntos
Competência Clínica , Colonografia Tomográfica Computadorizada/normas , Fadiga/fisiopatologia , Europa (Continente) , Humanos , Modelos Lineares , Variações Dependentes do Observador , Fatores de Tempo
16.
Eur Radiol ; 16(8): 1737-44, 2006 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-16636803

RESUMO

The extent measurement error on CT colonography influences polyp categorisation according to established management guidelines is studied using twenty-eight observers of varying experience to classify polyps seen at CT colonography as either 'medium' (maximal diameter 6-9 mm) or 'large' (maximal diameter 10 mm or larger). Comparison was then made with the reference diameter obtained in each patient via colonoscopy. The Bland-Altman method was used to assess agreement between observer measurements and colonoscopy, and differences in measurement and categorisation was assessed using Kruskal-Wallis and Chi-squared test statistics respectively. Observer measurements on average underestimated the diameter of polyps when compared to the reference value, by approximately 2-3 mm, irrespective of observer experience. Ninety-five percent limits of agreement were relatively wide for all observer groups, and had sufficient span to encompass different size categories for polyps. There were 167 polyp observations and 135 (81%) were correctly categorised. Of the 32 observations that were miscategorised, 5 (16%) were overestimations and 27 (84%) were underestimations (i.e. large polyps misclassified as medium). Caution should be exercised for polyps whose colonographic diameter is below but close to the 1-cm boundary threshold in order to avoid potential miscategorisation of advanced adenomas.


Assuntos
Pólipos do Colo/diagnóstico por imagem , Colonografia Tomográfica Computadorizada , Distribuição de Qui-Quadrado , Competência Clínica , Pólipos do Colo/patologia , Colonoscopia , Diagnóstico Diferencial , Europa (Continente) , Feminino , Humanos , Masculino , Variações Dependentes do Observador , Estatísticas não Paramétricas
17.
J Biomech ; 39(4): 627-35, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16439232

RESUMO

The present study explores the hypothesis that a high intra-abdominal pressure (IAP) loads the ligaments of the pelvic girdle to such an extent that frequent periods of high IAP might cause pain and/or interfere with recovery of patients with pelvic girdle pain (PGP). In a theoretical model the size of the load of IAP on the pelvic girdle was computed. The diameters of abdomen and pelvis needed for the calculations were measured on MRI scans; the IAP values during activities were gained from literature. In slim, healthy subjects the calculated load on the pelvic ring during activities of daily living was 26.0-52.0 N with peaks to 135 N. During straining, vigorous work or heavy exercises the load could increase to values ranging from 104 to 520 N. The load is higher in subjects with pain or fatigue, or in case of a distended abdomen. When the load on the pelvic ring induced by IAP is larger than 100 N, the force exceeds the force at which a pelvic belt relieves complaints in PGP; at 90 N, the force is larger than the force at which isometric hip adduction provokes pain in PGP. We conclude that the size of the load induced by IAP on the pelvic girdle seems to be sufficient to cause pain in patients with PGP and might interfere with recovery. It seems worthwhile to give patients with PGP instructions to reduce IAP as much as possible during activities.


Assuntos
Abdome/fisiopatologia , Modelos Biológicos , Dor Pélvica/etiologia , Dor Pélvica/fisiopatologia , Pelve/fisiopatologia , Medição de Risco/métodos , Simulação por Computador , Humanos , Manometria , Dor Pélvica/prevenção & controle , Pressão , Fatores de Risco
18.
Radiology ; 236(3): 886-95, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16014438

RESUMO

PURPOSE: To prospectively compare external phased-array magnetic resonance (MR) imaging with endoanal MR imaging in depicting external and internal anal sphincter defects in patients with fecal incontinence and to prospectively evaluate observer reproducibility in the detection of external and internal anal sphincter defects with both MR imaging techniques. MATERIALS AND METHODS: The medical ethics committees of both participating hospitals approved the study, and informed consent was obtained. Thirty patients (23 women, seven men; mean age, 58.7 years; range, 37-78 years) with fecal incontinence underwent MR imaging with both endoanal and external phased-array coils. MR images were evaluated by three radiologists with different levels of experience for external and internal anal sphincter defects. Measures of inter- and intraobserver agreement of both MR imaging techniques and of differences between both imaging techniques were calculated. RESULTS: Both MR imaging techniques did not significantly differ in the depiction of external (P > .99) and internal (P > .99) anal sphincter defects. The techniques corresponded in 25 (83%) of 30 patients for the depiction of external anal sphincter defects and in 28 (93%) of 30 patients for the depiction of internal anal sphincter defects. Interobserver agreement was moderate to good for endoanal MR imaging and poor to fair for external phased-array MR imaging. Intraobserver agreement ranged from fair to very good for both imaging techniques. CONCLUSION: External phased-array MR imaging is comparable to endoanal MR imaging in the depiction of clinically relevant anal sphincter defects. Because of the weak interobserver agreement, both MR imaging techniques can be recommended in the diagnostic work-up of fecal incontinence only if sufficient experience is available.


Assuntos
Canal Anal/fisiopatologia , Incontinência Fecal/fisiopatologia , Imageamento por Ressonância Magnética/métodos , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes
19.
J Endovasc Ther ; 10(3): 681-3, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12932188

RESUMO

PURPOSE: To report successful coil embolization of a rare traumatic pulmonary artery pseudoaneurysm. CASE REPORT: A 57-year-old man developed a pulmonary artery pseudoaneurysm 14 days after he had been stabbed with a knife in the left lung. The pseudoaneurysm was diagnosed with contrast-enhanced computed tomography and confirmed by pulmonary arteriography. Coils were deployed in the feeding vessels to occlude the defect. CONCLUSIONS: Pulmonary artery pseudoaneurysm after penetrating chest injury can be treated by percutaneous catheter embolization, which is less invasive than surgery.


Assuntos
Falso Aneurisma/terapia , Embolização Terapêutica , Artéria Pulmonar , Ferimentos Penetrantes/complicações , Falso Aneurisma/etiologia , Embolização Terapêutica/métodos , Humanos , Masculino , Pessoa de Meia-Idade
20.
J Endovasc Ther ; 10(2): 244-8, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12877606

RESUMO

PURPOSE: To report techniques for excluding the dilated false lumen associated with chronic type B aortic dissection following placement of a stent-graft in the true lumen. CASE REPORTS: Two patients underwent stent-graft implantation for a dilated false lumen after chronic aortic dissection, but the false lumen was not excluded from the circulation by this procedure. The false lumen was obliterated in one case with Greenfield filters and detachable balloons placed above a renal artery orifice that was perfused via the false lumen. This acted like "a cork in the bottleneck" to block retrograde flow into the thoracic portion of the false lumen above the blockade. In the other patient, an occluder device was used as the "cork." In both cases, a good result was obtained. The occluder device is preferred because deployment is more controllable. CONCLUSIONS: An occluder device may be used like a cork in a bottle to exclude the dilated false lumen in the thoracic aorta after a type B dissection.


Assuntos
Angioplastia/efeitos adversos , Aneurisma da Aorta Torácica/cirurgia , Dissecção Aórtica/cirurgia , Implante de Prótese Vascular/métodos , Endotélio Vascular/patologia , Complicações Pós-Operatórias/prevenção & controle , Idoso , Implante de Prótese Vascular/efeitos adversos , Dilatação Patológica/prevenção & controle , Feminino , Humanos , Masculino
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