[Idiopathic mucinosis cutis in Chinese Shar pei dogs: epidemiology, clinical features, histopathologic findings and treatment]. / Idiopathische Mucinosis cutis beim Chinesischen Shar Pei: Epidemiologie, klinisches Bild, histopathologische Befunde und Behandlung.

Species specific diseases, e.g. idiopathic mucinosis of the Chinese Shar Pei are reported by use of 31 clinical cases and 140 biopsy samples. Idiopathic mucinosis is one of the most frequent diseases of this increasing breed in Germany, too. The disease is diagnosed by use of histologic examination of skin biopsies. Therapy is performed by application of corticosteroids and symptomatic treatment.

[Small animal contribution to pediatric oncology]. / Beitrag zur pädiatrischen Onkologie beim Kleintier.

Retrospective analysis of biopsy material submitted to an Institute of Veterinary Pathology by private veterinary practitioners from 1993-1995 revealed tumors in 157 dogs and 71 cats under one year of age. Both histiocytomas and papillomas were excluded from the study. In the dog 55% (n = 87) and in the cat 73% (n = 52) of all tumors were diagnosed as malignant. In the dog tumors in order of frequency were: mammary neoplasia (n = 24, of those n = 10 malignant), soft tissue sarcomas (n = 24), hematopoietic tumors (n = 23), benign mesenchymal tumors (n = 16), mast cell tumors (n = 15), odontogenic tumors (n = 9), melanomas (n = 9, of those n = 5 malignant), osteosarcoma (n = 6), others (n = 31). In the feline, sarcomas were most common and of those hematopoietic tumors (lymphoma n = 23; 32%; mast cell tumors n = 12; 17%) were the two largest groups. The remaining sarcomas were 13 soft tissue sarcomas (18%) of which fibrosarcomas (n = 8) were most prevalent. Carcinomas where diagnosed in only 2 cases whereas among benign neoplasms (n = 19; 27%), epithelial tumors were the largest group (n = 14). In the order of frequency the following benign neoplasias were identified: fibroadenoma of mammary gland (n = 5), odontogenic tumors (n = 5), benign soft tissue tumors (n = 4), others (n = 6).

[Osteosarcoma in cats: epidemiological, clinical and radiological findings in 78 animals (1990-1995)]. / Das Osteosarkom der Katze: epidemiologische, klinische und röntgenologische Befunde bei 78 Tieren (1990-1995).

In this study 78 cats with osteosarcoma were identified from biopsy logs and evaluated retrospectively regarding breed, sex, and age distribution, tumor location, clinical symptoms, radiographic findings, biologic behavior of the neoplasm, and outcome following therapy. There was no significant breed or sex prediffection among the cats. The average age was 10.1 years, with a range of less than one to over 17 years. 36 (46%) of the osteosarcomas were localized in the bones of the limbs, 42 (54%) were found in flat or irregular bones. The hind limbs (25 cases) were affected significantly more often than the front limbs (10 cases). The most prevalent sites were the distal femur, proximal tibia, the humerus and the digits. Four of the tumors occurred after osteosynthesis of a previous fracture. In most of the cats limb tumors were associated with chronic lameness. The skull was the most common site for tumors of the flat and irregular bones (35 cases), which involved the oral cavity in 27 cases. The most common symptoms were dental problems, deformations of the skull, and nasal discharge. The remaining tumors of the flat and irregular bones were located in the pelvis (3), vertebrae (2), scapula (1), and rib (1). Radiographic findings were very variable and ranged from lytic to purely osteoproliferative forms. With tumors of the flat and irregular bones, tumor recurrence was a common cause for euthanasia. Animals with tumors of the limbs had a good prognosis following amputation.

[Two cases of colitis cystica profunda in dogs]. / Zwei Fälle von Colitis cystica profunda beim Hund.

Colitis cystica profunda in dogs has been diagnosed in one case only. The two own cases were characterized by repeated, partly bloody diarrhea, vomitus, and painful defecation. The disease was diagnosed by clinical examination and colonoscopy with the ensuing histological examination of biopsy specimens. The disease could be managed by administration of a diet, sulfasalazine and corticosteroids.

[The ultrastructure of mixed mammary gland tumors in bitches. IV. The incidence of myoepithelial cells in formation of spindle cells (author's transl)]. / Uber die Feinstruktur von Mammamischtumoren der Hündin. IV. Das Vorkommen von Myoepithelzellen in Spindelzellverbänden

Spindle cells of myomatous formations of 19 canine mixed mammary tumors were studied by light and electron microscopy. The EM findings indicate that the spindle-shaped tumor cells are mostly of myoepithelial origin. However there were also formations of spindle cells which consisted of fibroblasts or fibrocytes. By light microscopy they are not always clearly distinguishable.

[The ultrastructure of mixed mammary gland tumours in bitches. III. The early stages of the myoepithelial proliferation (author's transl)]. / Uber die Feinstruktur von Mammamischtumoren der Hündin. III. Die Anfangsstadien der myoepithelialen Proliferation

The early stages of myoepithelial proliferation in 14 mixed canine mammary tumours were studied by light- and electron microscopy. Two different early stages can be distinguished: 1. Proliferations inside the basal lamina with partial maintenance of the organoid pattern. 2. Proliferations with a break through the basal lamina and transposition of tumour cells into the surrounding connective tissue. The intracytoplasmic fibrillae of myoepithelial tumour cells are striped periodically and thicker than those of normal myothelia. It is suggested that the amorphous as well as the fibrous intercellular substance in the early stages is derived from the described myoepithelial tumour cells.