RESUMO
Iron deficiency (ID) without anaemia frequently remains undiagnosed when symptoms are attributed to ID with anaemia. Serum ferritin is the primary diagnostic parameter, whereas <10 microg/l represent depleted iron stores, 10-30 microg/l can confirm ID without anaemia and 30-50 microg/l might indicate functional ID. In case of increased CRP or ALT, normal/elevated ferritin should be interpreted with caution. IV iron is indicated if oral iron is not effective or tolerated. At ferritin <10 microg/l, a cumulative dose of 1000 mg iron and at ferritin 10-30 microg/l, a cumulative dose of 500 mg is advised. At ferritin 30-50 microg/l a first dose of 200 mg might be considered. Ferritin shall be reassessed not sooner than 2 weeks after the last oral or 8-12 weeks after the last IV iron administration.
Assuntos
Deficiências de Ferro , Deficiências Nutricionais/diagnóstico , Deficiências Nutricionais/tratamento farmacológico , HumanosRESUMO
Iron deficiency (ID) without anaemia frequently remains undiagnosed when symptoms are attributed to ID with anaemia. Serum ferritin is the primary diagnostic parameter, whereas <10 microg/l represent depleted iron stores, 10-30 microg/l can confirm ID without anaemia and 30-50 microg/l might indicate functional ID. In case of increased CRP or ALT, normal/elevated ferritin should be interpreted with caution. Intravenous iron is indicated if oral iron is not effective or tolerated. At ferritin <10 microg/l, a cumulative dose of 1000 mg iron and at ferritin 10-30 microg/l, a cumulative dose of 500 mg is advised. At ferritin 30-50 microg/l a first dose of 200 mg might be considered. Ferritin shall be reassessed not sooner than 2 weeks after the last oral or 8-12 weeks after the last iv iron administration.
Assuntos
Anemia Ferropriva/diagnóstico , Deficiências de Ferro , Alopecia/sangue , Alopecia/etiologia , Anemia Ferropriva/sangue , Transtornos Cognitivos/sangue , Transtornos Cognitivos/etiologia , Estudos Transversais , Diagnóstico Diferencial , Formas de Dosagem , Fadiga/sangue , Fadiga/etiologia , Ferritinas/sangue , Humanos , Ferro/administração & dosagem , Ferro/sangue , Compostos de Ferro/administração & dosagem , Compostos de Ferro/efeitos adversos , Valores de Referência , Síndrome das Pernas Inquietas/sangue , Síndrome das Pernas Inquietas/etiologiaRESUMO
Many chronic pain conditions cannot be classified correctly into the actual categories of nociceptive, neuropathic, or psychogenic pain. The experience that a therapeutic influence on the vegetative nervous system often improves these pains or induces healing of them suggests a classification into four pain types. The inclusion of the autonomic component in the appreciation, and the treatment of chronic pain conditions using measures acting on the vegetative nervous system (such as local anesthetics in the neural therapy of Huneke) will consistently enlarge and improve the understanding and the outcome in pain therapy.
