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Internist (Berl) ; 56(5): 566-72, 2015 May.
Artigo em Alemão | MEDLINE | ID: mdl-25874738

RESUMO

A 73-year-old female patient who had received a liver and kidney transplantation presented with symptomatic pancytopenia and right-sided upper abdominal pain. The histological investigation of a bone marrow biopsy showed the extremely rare manifestation of a disseminated Merkel cell carcinoma with infiltration of the bone marrow and suppression of hematopoiesis. Also a Coombs test positive hemolytic anemia did not show a significant response to high-dose steroid therapy. Palliative chemotherapy with carboplatin and etoposide at reduced dosage had to be terminated due to deterioration of the patient's general condition. The patient died 2 days after initiation of chemotherapy.


Assuntos
Dor Abdominal/etiologia , Carcinoma de Célula de Merkel/diagnóstico , Carcinoma de Célula de Merkel/etiologia , Epistaxe/etiologia , Transplante de Rim/efeitos adversos , Transplante de Fígado/efeitos adversos , Idoso , Antineoplásicos/uso terapêutico , Carcinoma de Célula de Merkel/tratamento farmacológico , Terapia Combinada/efeitos adversos , Diagnóstico Diferencial , Epistaxe/diagnóstico , Evolução Fatal , Feminino , Humanos , Recidiva
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