Coffee Consumption and the Risk of All-Cause and Cause-Specific Mortality in the Korean Population.

BACKGROUND: There is a dearth of information regarding the association between coffee consumption and its health effects with respect to mortality among Korean people. OBJECTIVE: The aim of this study was to examine the association between coffee consumption and all-cause mortality and cause-specific mortality risks in the Korean population. DESIGN: This prospective cohort study had a median follow-up period of 9.1 years. PARTICIPANTS/SETTING: In total, 173,209 participants aged 40 years and older from the Health Examinees study were enrolled between 2004 and 2013. The analytic sample included 110,920 participants without diabetes, cardiovascular disease (CVD), or cancer at baseline who could be linked with their death information. MAIN OUTCOME MEASURES: Deaths of participants until December 31, 2018 were ascertained using the death certificate database of the National Statistical Office. Cause of death was classified according to the International Classification of Diseases, 10th Revision. STATISTICAL ANALYSES PERFORMED: Participants were categorized according to the amount and type of coffee consumed. Cox proportional hazards regression analysis was performed to estimate the hazard ratio (HR) and 95%CI of all-cause mortality and cause-specific mortality, such as CVD and cancer mortality. RESULTS: Compared with nonconsumers of coffee, participants who consumed > 3 cups/day had a reduced risk of all-cause mortality (HR 0.79, 95% CI 0.66 to 0.95). Participants who consumed ≤1 cup/day and 1 to 3 cups/day had a reduced risk of CVD mortality (≤1 cup/day: HR 0.58, 95% CI 0.69 to 0.94; 1 to 3 cups/day: HR 0.62, 95% CI 0.41 to 0.96). CONCLUSIONS: This study provides evidence that greater coffee consumption is associated with a decreased risk of all-cause mortality and moderate coffee consumption (approximately 3 cups/day) is associated with a decreased risk of CVD mortality, regardless of the type of coffee, in a Korean population.

The Association between Coffee Consumption Pattern and Prevalence of Metabolic Syndrome in Korean Adults.

The inconsistent results of epidemiologic studies suggest that the health effects of coffee vary depending on coffee consumption pattern, such as the type and amount of coffee intake. This study investigated the association between coffee consumption and metabolic syndrome (MetS) in Korean adults. In total, coffee consumption patterns in 14,132 participants were assessed based on two-day, 24-h recall data. Multivariable logistic regression was used to examine the association between the type and daily servings of coffee and the prevalence of MetS. In women, the prevalence of MetS (odds ratio (OR) 0.82; 95% confidence interval (CI): 0.70, 0.96), elevated triglycerides (0.85; 0.75, 0.97), and reduced high-density lipoprotein (HDL)-cholesterol (HDL-C; 0.74; 0.66, 0.83) in 3-in-1 coffee consumers, as well as the prevalence of increased waist circumference (0.81; 0.68, 0.98) and reduced HDL-C (0.68; 0.59, 0.80) in black coffee consumers, were significantly lower compared to non-coffee consumers. Also, the inverse associations between total coffee intake, black coffee intake, and 3-in-1 coffee intake with MetS or components of MetS were more significant in individuals who consumed >1 versus ≤1 serving/day. In conclusion, coffee consumption (regardless of type) was associated with a reduced prevalence of MetS and its components in Korean women.

Association of coffee consumption with health-related quality of life and metabolic syndrome in Korean adults: based on 2013 ~ 2016 Korea National Health and Nutrition Examination Survey / 한국영양학회지

PURPOSE: This study examined the association of the type and frequency of coffee consumption with the health-related quality of life and metabolic bio-markers in adult men and women from the 2013 ~ 2016 Korea National Health and Nutrition Examination Survey (KNHANES). METHODS: A total of 11,201 subjects (4,483 men and 6,718 women) were classified according to the type of coffee consumption (non-coffee, black coffee, 3-in-1 coffee) and type and frequency of coffee consumption (non-coffee, ≤2 times/day of black coffee, > 2 times/day of black coffee, ≤2 times/day of 3-in-1 coffee, > 2 times/day of 3-in-1 coffee) using food frequency questionnaires. Dietary nutrient intake data were assessed using food frequency questionnaires. The health-related quality of life was measured using the EuroQol-5 dimension (EQ-5D) and EQ-5D index score. Data on metabolic bio-markers were obtained from a health examination. RESULTS: Among men and women, the proportion of subjects with an energy intake below the estimated energy requirement (EER) was lower among the 3-in-1 coffee consumption group, and the proportion of subjects with iron intakes below the estimated average requirements (EAR) was lower among the 3-in-1 coffee consumption group. Women (OR: 0.810, 95% CI: 0.657 ~ 0.998) with the ≤2 times/day of 3-in-1 coffee had a lower risk of impaired health-related quality of life (lowest 20% level in the EQ-5D score) compared to the non-coffee consumers after a multivariable adjustment. In both men and women, the type and frequency of coffee consumption was not associated with metabolic bio-markers risk after multivariable adjustment. CONCLUSION: These results suggest that 3-in-1 coffee consumption may be associated with a lower risk of impaired health-related quality of life and may not be associated with the metabolic bio-markers risk in adult men and women.

3-in-1 coffee consumption is associated with metabolic factors in adults: Based on 2012~2015 Korea National Health and Nutrition Examination Survey / 한국영양학회지

PURPOSE: This study was conducted to evaluate the risk of metabolic factors in adults consuming 3-in-1 coffee from the 2012~2015 Korea National Health and Nutrition Examination Survey (KNHANES). METHODS: A total of 5,872 subjects (male = 2,253, female = 3,619) aged 19~64 yrs were presented with food frequency questionnaires, and they were classified according to coffee consumption level and types of coffee consumed (black coffee, ≤1 time/day of 3-in-1 coffee, > 1 and ≤2 times/day of 3-in-1 coffee, > 2 times/day of 3-in-1 coffee). Analysis was conducted by gender for age-stratified groups: 19~39 (male = 968 and female = 1,285) and 40~64 (male = 1,468, female = 2,151) yrs old. RESULTS: Black coffee consumption was associated with a significantly higher education level and household income compared to 3-in-1 coffee consumption in both males and females. The > 2 times/day group had significantly more smokers compared to other patterns of coffee consumption in both males and females. In the 40~64 yrs age group, males and females in the > 2 times/day group had significantly lower density of micronutrients such as fiber, niacin, vitamin C, calcium, phosphorus,and potassium compared with black coffee consumption. In the 40~64 yrs age group, males (OR: 2.03, 95% CI: 1.13~3.64) in the > 2 times/day group were at a higher risk of metabolic syndrome compared with black coffee consumption after multivariable adjustment. CONCLUSION: We found that frequency of 3-in-1 coffee consumption may be associated with prevalence of metabolic syndrome in males aged 40~64 yrs.