RESUMO
[Objective] To investigate the effect of external application of osmosis-improving herbal medicine and enema with blood-activating and stasis-removing herbal medicine for chronic pelvic inflammation. [Methods] Single-blind and randomized trial was performed on 120 cases of chronic pelvic inflammation. The cases were randomized to two groups: group A ( n = 57) was treated by enema with blood-activating and stasis-removing herbal medicine and group B ( n = 63) by the combination of enema and external application of osmosis-improving herbal medicine. Fourteen days constituted one course of treatment and the therapeutic effect was evaluated after two courses. [Results] In group A, 30 cases were cured, 21 effective, 6 ineffective and the total effective rate was 89.5%; 43 were cured, 18 effective, 2 ineffective and the total effective rate was 96.8% in group B. The result of Ridit analysis showed that the effect of group B was better than that of group A ( t = 3.08, P
RESUMO
Objective To explore the main pharmacological actions of Penyan Qing Capsule (PQC) for chronic pelvic inflammation. Methods The analgesic action of PQC was studied by mouse hot_plate method. Experiments of mouse auricular swell ing and rat agar_induced granuloma were carried out to investigate the anti_infl ammatory action of PQC. Effects of PQC on function of mouse mononuclear phagocyt es and rat mesenteric microcirculation were also studied. Results PQC increa sed the rat pain threshold, reduced mouse auricular swelling induced by xylene a nd the weight of rat agar_induced granuloma. PQC could also improved rat mesente ric microcirculation disorder induced by noradrenline and increase the function of mouse mononuclear phagocytes. Conclusion PQC exerts good anti_inflammatory and analagisic action and can improve microcirculation. This will supply pharm acodynamic evidence for the application of PQC in clinic.
