[Efficacy of bioregulative drugs in the treatment of otitis media with effusion associated with rhinosinusitis and adenoiditis]. / Effektivnost' preparatov bioregulyatsionnoi meditsiny pri lechenii ekssudativnogo srednego otita, sopryazhennogo s rinosinusitom i adenoiditom.

PURPOSE: Improving of otitis media with effusion (OME) with rhinosinusitis (RS) and adenoiditis treatment effectiveness. MATERIALS AND METHODS: The study included 112 patients 12-18 y.o. with otitis media with effusion, who were divided into 2 groups depending on the treatment scheme. The Group I (the main group) patients treatment included Traumeel S and Euphorbium compositum Nasentropfen S in addition to the standard treatment, and the Group II (comparison), children were prescribed standard therapy. Patients of both groups were divided into 3 subgroups depending on the upper respiratory tract inflammation symptoms: A - patients with adenoiditis; B - with rhinosinusitis and C - combination of adenoiditis and rhinosinusitis. The comparison group (groups IIB and IIC) treatment scheme (children with rhinosinusitis) included topical corticosteroids and the main group patients didn't receive corticosteroids. All patients went through complaints and anamnesis collection, routine otorhinolaryngological and instrumental examination before and after treatment. RESULTS: Analysis of treatment results demonstrated high efficacy of multicomponent drugs with low doses of active ingredients in the therapy of patients with OME, regardless of comorbid pathology. Significantly better results were obtained in the patients treated with bioregulatory drugs when comparing the outcomes of OME therapy in combination with adenoiditis (groups IA and IIA). Comparable efficacy results were obtained in the treatment group of patients with OME associated with RS (in groups IB and IIB as well as in groups IC and IIC), where GCS was received in the comparison group. The high efficacy and safety of bioregulatory drugs makes the use of these agents a promising treatment for patients with OME, RS and adenoiditis.

Medicamentos dinamizados injetáveis disponíveis no Brasil: indicações baseadas na homotoxicologia e possibilidades de uso pela visão antroposófica / Potentized injectable medicines available in Brazil: indications based on homotoxicology and possibilities of use according to anthroposophic medicine

A medicina biorreguladora utiliza medicamentos homeopáticos multicomponentes para tratar processos patológicos de forma harmônica à complexa rede fisiológica do organismo humano. No Brasil, dispomos atualmente de seis medicamentos injetáveis desta natureza: Traumeel® S, de ação anti-inflamatória; Zeel® comp. N para quadros de osteoartroses; Nux vomica-Homaccord®, para distúrbios gastrintestinais; Spascupreel®, para quadros espasmódicos de musculatura lisa e estriada; Gripp-Heel®, para quadros gripais e resfriados; e Vertigoheel®, para quadros vertiginosos, preparados segundo a farmacotécnica homeopática e indicados de acordo com as matérias médicas homeopáticas. Para cada medicação citada, existem estudos clínicos e in vitro para avaliação de eficácia, de seus mecanismos de ação farmacológicos e de seu perfil de tolerabilidade. De acordo com sua constituição homeopática, as medicações também serão analisadas sob a ótica da medicina antroposófica neste artigo. A biopuntura é uma técnica de administração parenteral destas medicações e segue os princípios de somatotopia e áreas de referência visceral. As administrações podem ser realizadas de forma subcutânea, intramuscular, intra-articular ou intravenosa. A utilização em milhares de pacientes destas medicações nos últimos sessenta anos mostrou-se extremamente segura e efetiva para as indicações aprovadas.(AU)

The bioregulatory medicine uses homeopathic multi-component drugs to treat pathological process in harmony to the complex physiologic net of the human organism. Currently, in Brazil there are six injectable medicines of this nature: Traumeel® S, with an anti-inflammatory action; Zeel® comp. N, for osteoarthritis conditions; Nux vomica-Hommacord®, for gastrointestinal disorders; Spascupreel®, for smooth and skeletal muscle spasmodic conditions; Gripp-Heel®, for common cold and influenza; and Vertigoheel® for vertigo; they have been prepared in accordance to the homeopathic pharmacopeia and indicated according to homeopathic materia medica. For each of these medications, there are clinical trials and in vitro studies to evaluate their efficacy, pharmacological mechanisms of action and tolerability profile. In accordance to its homeopathic nature, the medicines are also evaluated by the anthroposophic medicine concept. Biopuncture is a parenteral administration technique for these medications e follows the somatotopy and reference cutaneous areas principles. The medicine administration can be performed in subcutaneous, intramuscular, intra-articular and intravenous forms. Thousands of patients have been treated with these medications in the last sixty years with an excellent safety profile and proven efficacy for their approved indications. (AU)