RESUMO
The first case report of human dipylidiasis in Venezuela is presented, including the diagnosis and treatment of a two-year-old child's infection. The diagnosis was parasitologically confirmed, the child was treated with praziquantel and the animal reservoir and its fleas were identified
Se presenta el primer caso de dipylidiasis humana en Venezuela, incluyendo el diagnóstico y el tratamiento de la infección de un niño de dos años. El diagnóstico fue confirmado parasitológicamente, se trató al niño con praziquantel y fueron identificados el reservorio animal y sus pulgas
RESUMO
BACKGROUND: Randomized controlled trials have found an inconsistent effect of anthelmintic treatment on long-term seizure outcomes in neurocysticercosis. The objective of this study was to further explore the effect of albendazole treatment on long-term seizure outcomes and to determine if there is evidence for a differential effect by seizure type. METHODS: In this trial, 178 patients with active or transitional neurocysticercosis cysts and new-onset symptoms were randomized to 8 days of treatment with albendazole (n=88) or placebo (n=90), both with prednisone, and followed for 24 months. We used negative binomial regression and logistic regression models to determine the effect of albendazole on the number of seizures and probability of recurrent or new-onset seizures, respectively, over follow-up. RESULTS: Treatment with albendazole was associated with a reduction in the number of seizures during 24 months of follow-up, but this was only significant for generalized seizures during months 1-12 (unadjusted rate ratio [RR] 0.19; 95% CI: 0.04-0.91) and months 1-24 (unadjusted RR 0.06; 95% CI: 0.01-0.57). We did not detect a significant effect of albendazole on reducing the number of focal seizures or on the probability of having a seizure, regardless of seizure type or time period. CONCLUSIONS: Albendazole treatment may be associated with some symptomatic improvement; however, this association seems to be specific to generalized seizures. Future research is needed to identify strategies to better reduce long-term seizure burden in patients with neurocysticercosis.
Assuntos
Albendazol/uso terapêutico , Anti-Helmínticos/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Encéfalo/parasitologia , Neurocisticercose/tratamento farmacológico , Convulsões/parasitologia , Animais , Encéfalo/patologia , Cistos/parasitologia , Quimioterapia Combinada , Equador/epidemiologia , Feminino , Seguimentos , Humanos , Masculino , Neurocisticercose/complicações , Neurocisticercose/fisiopatologia , Prednisona/uso terapêutico , Recidiva , Fatores de Tempo , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
La difilobotriosis es una parasitosis intestinal causada por la infección de cestodos del genero Diphyllobothrium. En la Argentina, la Patagonia Andina es considerada una zona endémica para esta parasitosis. La infección por Diphyllobothrium latum no ha sido previamente notificada en la provincia de Mendoza; en este trabajo comunicamos un caso de esta parasitosis que fue confirmada por el análisis de las características morfológicas de los huevos eliminados con la materia fecal de un paciente infectado. Se destaca la necesidad de información y capacitación de los profesionales de la salud en el diagnóstico y tratamiento de parasitosis no endémicas.(AU)
Diphyllobothriosis is an intestinal parasitosis caused by cestodes infection of the genus Diphyllobothrium. In Argentina, the Andean Patagonia is considered an endemic area for this parasitosis. Diphyllobothrium latum infection has not been previously reported in the province of Mendoza, Argentina. We are now reporting then the first case. Diphyllobothriosis was confirmed by examination of morphologic characteristics of the eggs eliminated in the patients feces. These results suggest the requirement of a more specific training of health workers in the diagnosis and treatment of non endemic parasitosis. We want to emphasize the need of health workers education on diagnosis and treatment of endemic and non-endemic parasitosis.(AU)
Assuntos
Animais , Humanos , Masculino , Adulto Jovem , Difilobotríase/diagnóstico , Diphyllobothrium/isolamento & purificação , Parasitologia de Alimentos , Oncorhynchus kisutch/parasitologia , Argentina/epidemiologia , Contagem de Ovos de ParasitasRESUMO
La difilobotriosis es una parasitosis intestinal causada por la infección de cestodos del genero Diphyllobothrium. En la Argentina, la Patagonia Andina es considerada una zona endémica para esta parasitosis. La infección por Diphyllobothrium latum no ha sido previamente notificada en la provincia de Mendoza; en este trabajo comunicamos un caso de esta parasitosis que fue confirmada por el análisis de las características morfológicas de los huevos eliminados con la materia fecal de un paciente infectado. Se destaca la necesidad de información y capacitación de los profesionales de la salud en el diagnóstico y tratamiento de parasitosis no endémicas.(AU)
Diphyllobothriosis is an intestinal parasitosis caused by cestodes infection of the genus Diphyllobothrium. In Argentina, the Andean Patagonia is considered an endemic area for this parasitosis. Diphyllobothrium latum infection has not been previously reported in the province of Mendoza, Argentina. We are now reporting then the first case. Diphyllobothriosis was confirmed by examination of morphologic characteristics of the eggs eliminated in the patients feces. These results suggest the requirement of a more specific training of health workers in the diagnosis and treatment of non endemic parasitosis. We want to emphasize the need of health workers education on diagnosis and treatment of endemic and non-endemic parasitosis.(AU)
Assuntos
Animais , Humanos , Masculino , Adulto Jovem , Difilobotríase/diagnóstico , Diphyllobothrium/isolamento & purificação , Parasitologia de Alimentos , Oncorhynchus kisutch/parasitologia , Argentina/epidemiologia , Contagem de Ovos de ParasitasRESUMO
La difilobotriosis es una parasitosis intestinal causada por la infección de cestodos del genero Diphyllobothrium. En la Argentina, la Patagonia Andina es considerada una zona endémica para esta parasitosis. La infección por Diphyllobothrium latum no ha sido previamente notificada en la provincia de Mendoza; en este trabajo comunicamos un caso de esta parasitosis que fue confirmada por el análisis de las características morfológicas de los huevos eliminados con la materia fecal de un paciente infectado. Se destaca la necesidad de información y capacitación de los profesionales de la salud en el diagnóstico y tratamiento de parasitosis no endémicas.
Diphyllobothriosis is an intestinal parasitosis caused by cestodes infection of the genus Diphyllobothrium. In Argentina, the Andean Patagonia is considered an endemic area for this parasitosis. Diphyllobothrium latum infection has not been previously reported in the province of Mendoza, Argentina. We are now reporting then the first case. Diphyllobothriosis was confirmed by examination of morphologic characteristics of the eggs eliminated in the patients' feces. These results suggest the requirement of a more specific training of health workers in the diagnosis and treatment of non endemic parasitosis. We want to emphasize the need of health workers' education on diagnosis and treatment of endemic and non-endemic parasitosis.
Assuntos
Animais , Humanos , Masculino , Adulto Jovem , Difilobotríase/diagnóstico , Diphyllobothrium/isolamento & purificação , Parasitologia de Alimentos , Oncorhynchus kisutch/parasitologia , Argentina/epidemiologia , Contagem de Ovos de ParasitasRESUMO
Se presentan 2 pacientes del sexo femenino y de la raza blanca, de 11 meses y 1 año de edad, respectivamente, con parasitismo intestinal por Inermicapsifer madagascariensis (Inermicapsifer cubensis) atendidas en la consulta externa de Pediatría del Instituto de Medicina Tropical "Pedro Kourí" durante los últimos 3 años. Ambas pacientes, con historia de expulsar parásitos por el ano, que no curaban con los diversos tratamientos utilizados para taeniasis, fueron remitidas a este centro donde se hizo el diagnóstico de Inermicapsifer madagascariensis y se les aplicó el tratamiento específico con Praziquantel, desapareciendo el parasitismo.
Two female white patients of 11 months and 1 year of age, respectively, with intestinal parasitism due to Inermicapsifer madagascariensis (Inermicapsifer cubensis) are presented. They were attended at the Pediatrics Outpatient Department of the "Pedro Kourí" Institute of Tropical Medicine during the last 3 years. Both patients who did not cure with the different treatment used against taeniasis and who used to expel parasites through the snus, were referred to this center, where they were diagnosed Inermicapsifer madagascariensis. Parasitism dissapeared with a specific treatment with Praziquantel.