Cognitive Capacities as Functional Natural Kinds.

In this paper, we articulate a functional approach to cognitive capacities. It is a restricted functionalism for various reasons, but especially because it does not claim that all cognitive (and/or mental) entities and processes are functional in the sense of a systemic capacities approach. One of the central aims of a cognitive theory consists in providing explanations of behavioral phenomena of (human and non-human) animals, and of the phenomena that are involved in those explanations. We accept that part of what lies at the heart of these explanations are certain functional entities -we call them "cognitive functional systems" -which in our view stand for most of the cognitive capacities of an organism; that is, systems that are individuated primarily by the main cognitive functions they undertake. Additionally, in the paper, we go into further detail concerning these functional systems, their internal organization, the nature of their causal interactions, etc. We also argue that some of these classes of cognitive functional systems (i.e., cognitive capacities) can be construed as "natural kinds" whenever their kinds of functional organizations are understood as kinds of hierarchically ordered classes of information processing events that are related among each other in regular (often complex) ways.

Falling through the cracks: Failing to identify compromised Miranda abilities for defendants with limited cognitive capacities.

Custodial suspects must be informed of their Miranda rights (Miranda v. Arizona, 1966) prior to police questioning. Since this landmark decision, scholars have rigorously studied Miranda comprehension and reasoning among vulnerable groups including those with intellectual disabilities (ID). However, the focus on ID has left arrestees with limited cognitive capacities (i.e., LCCs with IQs between 70 and 85) entirely overlooked. The current dataset addressed this oversight using a large (N = 820) sample of pretrial defendants who had completed the Standardized Assessment of Miranda Abilities (SAMA). Traditional (i.e., ID and no-ID) criterion groups were first analyzed with the standard error of measurement (SEM) removed. Second, a nuanced three-group framework included defendants with LCCs. Results indicate that LCC defendants are vulnerable to impaired Miranda comprehension (i.e., limited recall of the Miranda warning and deficits in Miranda-related vocabulary knowledge). Not surprisingly, their waiver decisions were often impaired by crucial misconceptions (e.g., seeing the investigating officers as beneficently on their side). The practical implications of these findings were underscored with respect to Constitutional safeguards for this critically important group, who have appeared to fall through the cracks in the criminal justice system.

The association between visual attention and arithmetic competence: The mediating role of enumeration.

The current study aimed at clarifying the nature of relation between visual attention and arithmetic competence. A group of 301 Chinese second graders was assessed. Children's visual attention was measured using two versions of a visual search task, with efficient visual search (the similarity between the target and the distractors is low) tapping automatic, stimulus-driven visual attention and inefficient visual search (the similarity between the target and the distractors is high) tapping effortful, goal-directed visual attention. Children's arithmetic competence, enumeration skills (assessed in about half of the participants), and other domain-general cognitive abilities were also assessed. The results suggest that only inefficient visual search significantly predicted children's arithmetic competence, and such a relation was mediated through their enumeration skills. The findings highlight the role of fundamental cognitive capacities in mathematics learning and provide insights into potential interventions for improving children's arithmetic competence.

Sleep and the GH/IGF-1 axis: Consequences and countermeasures of sleep loss/disorders.

This article presents an up-to-date review of the state-of-the-art knowledge regarding the effect of sleep on the anabolic growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis. This axis is involved in learning and memory and neuroprotection at the central level, and in the crosstalk between sleep and the immune system, with respect to its anti-inflammatory properties. We also aim to provide insight into the consequences of sleep loss on cognitive capacities in healthy individuals and patients with obstructive sleep apnea (OSA), regarding the mechanistic association with the GH/IGF-1 axis. Finally, this review examines the inflammatory/endocrine pathways that are affected by sleep loss, and which may consequently interact with the GH/IGF-1 axis. The deleterious effects of sleep loss include fatigue, and can cause several adverse age-dependent health outcomes. It is therefore important to improve our understanding of the fundamental physiology underlying these effects in order to better apply non-pharmacological countermeasures (e.g., sleep strategies, exercise training, continuous positive airway pressure therapy) as well as pharmacological solutions, so as to limit the deleterious consequences of sleep loss/disorders.

A framework for the ethical assessment of chimeric animal research involving human neural tissue.

BACKGROUND: Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological disorders difficult to study in humans, chimeric models with human neural tissue could help advance our understanding of neuropathophysiology. MAIN BODY: In this article, we examine whether the introduction of human neural tissue and any consequent cognitive change is relevant to the way we ought to treat chimeras. We argue that changes in cognitive abilities are morally relevant to the extent that they increase the capacities that affect the moral status of any entity, including awareness, autonomy, and sociability. We posit that no being, regardless of species, should be treated in a way that is incommensurate with its moral status. Finally, we propose a framework that can be used to guide ethical assessment of research involving chimeras with advanced cognitive capacities. CONCLUSION: We advance this framework as a useful tool for bringing relevant considerations to the forefront for those considering the ethical merit of proposed chimeric research. In doing so, we examine concepts relevant to the question of how any entity may be treated, including moral status, dignity, and capacities.

Effects of cognitive impairment on prosodic parameters of speech production planning in multiple sclerosis.

Cognitive impairment (CI) affects 40-65% of patients with multiple sclerosis (MS). CI can have a negative impact on a patient's everyday activities, such as engaging in conversations. Speech production planning ability is crucial for successful verbal interactions and thus for preserving social and occupational skills. This study investigates the effect of cognitive-linguistic demand and CI on speech production planning in MS, as reflected in speech prosody. A secondary aim is to explore the clinical potential of prosodic features for the prediction of an individual's cognitive status in MS. A total of 45 subjects, that is 22 healthy controls (HC) and 23 patients in early stages of relapsing-remitting MS, underwent neuropsychological tests probing specific cognitive processes involved in speech production planning. All subjects also performed a read speech task, in which they had to read isolated sentences manipulated as for phonological length. Results show that the speech of MS patients with CI is mainly affected at the temporal level (articulation and speech rate, pause duration). Regression analyses further indicate that rate measures are correlated with working memory scores. In addition, linear discriminant analysis shows the ROC AUC of identifying MS patients with CI is 0.70 (95% confidence interval: 0.68-0.73). Our findings indicate that prosodic planning is deficient in patients with MS-CI and that the scope of planning depends on patients' cognitive abilities. We discuss how speech-based approaches could be used as an ecological method for the assessment and monitoring of CI in MS.

Beyond an Open Future.

Discussions about the ethical permissibility of pediatric cognitive enhancement frequently revolve around arguments about welfare, and often include an appeal to the child's right to an open future. Both proponents and opponents of cognitive enhancement claim that their respective positions best serve the interests of the child by promoting an open future. This article argues that this right to an open future argument only captures some of the risks to the welfare of children, therefore requiring a broader ethical approach. Further, it suggests that a thorough moral assessment of the ends pursued is needed before concluding on the moral permissibility of cognitive enhancement in children, which ultimately hinges on the effect on the overall welfare of the child, beyond an open future.

Impacto que tiene la falta de sueño sobre las habilidades cognitivas de una población de estudiantes de medicina / Impact of sleep deprivation on the cognitive abilities of a population of medical students

Los estudiantes que ingresan a la Escuela de Medicina son personas que pasarán los próximos años de su vida preparándose para entender la composición, la anatomía y la fisiología tanto normal como patológica del cuerpo humano con el fin de luego, aplicar ese conocimiento en el tratamiento de sus pacientes. Sin embargo, ser estudiante de Medicina se ha descrito como un extenuante proceso en el cual los jóvenes sufren alteraciones notables en sus horas de sueño, niveles de estrés, presión y fustración emocional e incluso depresión. Esta investigación se llevó a cabo para identificar en una población de estudiantes de segundo semestre de segundo año de Medicina de la Universidad de Costa Rica, el deterioro cognitivo que puede tener dicho estilo de vida y cómo influye en la capacidad de aprendizaje y los resultados que estos pueden obtener. A través de la figura compleja de Rey-Osterrieth y la prueba MoCA (Montreal Cognitive Assesment) se evaluó la muestra en dos oportunidades distintas: al encontrarse los estudiantes en un período de evaluación normal y con un nivel de cansancio notable tras un período de evaluación más intenso. Los datos obtenidos comprobaron que efectivamente existe un deterioro en el rendimiento y las capacidades cognitivas de los jóvenes...