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1.
Materials (Basel) ; 17(12)2024 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-38930314

RESUMO

Polypropylene fiber reinforcement is an effective method to enhance the durability of concrete structures. With the increasing public interest in the widespread use of polypropylene fiber reinforced concrete (PFRC), the necessity of evaluating the mechanism of polypropylene fiber (PF) on the permeability of concrete has become prominent. This paper describes the influence of PF on the concrete permeability exposed to freeze-thaw cycles under compressive and tensile stress. The permeability of PFRC under compressive and tensile loads is accurately measured by a specialized permeability setup. The permeability of PFRC under compressive and tensile loads, the volume change of PFRC under compressive load, and the relationship between compressive stress levels at minimum permeability and minimum volume points of PFRC are discussed. The results indicate that the addition of PF adversely affects the permeability of concrete without freeze-thaw damage and cracks. However, it decreases the permeability of concrete specimens exposed to freeze-thaw cycles and cracking. Under compressive load, the permeability of PFRC initially decreases slowly and follows by a significant increase as the compressive stress level increases. This phenomenon correlates with the volume change of the specimen. The compressive stress level of the minimum permeability point and compressive stress level of the minimum volume point of PFRC exhibit a linear correlation, with a fitted proportional function parameter γ ≈ 0.98872. Under tensile load, the permeability of PFRC increases gradually with radial deformation and follows by a significant increase. The strain-permeability curves of PFRC under loading are studied and consist of two stages. In stage I, the permeability of PFRC gradually decreases with the increase of strain under compressive load, while the permeability increases with the increase of strain under tensile load. In stage II, under compressive load, the permeability of PFRC increases with the increase of freeze-thaw cycles, whereas under tensile load, the permeability gradually decreases with the increase of freeze-thaw cycles. The reduction of PF on the permeability of PFRC under tensile load is greater than that under compressive load. In future research, the relationship between strain and permeability of PFRC can be integrated with its constitutive relationship between stress and strain to provide a reference for the application of PF in the waterproofing of concrete structures.

2.
Sci Rep ; 14(1): 9317, 2024 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-38653748

RESUMO

Carbon fibre-reinforced polymer (CFRP) plates can efficiently repair or enhance the mechanical properties of the square hollow section. However, the loading end of such a CFRP-strengthened member is prone to local bearing failure under compressive load. Given this limitation, an innovative CFRP-plate-strengthened square hollow section composite member (CFRP-SHSCM) was raised, and the thick-walled section was welded on both ends of the thin-walled steel column. The mechanical properties of CFRP-SHSCMs were investigated through parameter finite element (FE) analysis, focusing on the influence of the amount of CFRP layers (nc), the slenderness ratio (λ), the initial geometric imperfections (v0), the CFRP layouts (2S and 4S) and the length of the exposed steel column (Le). The load-displacement curves, the bearing force, and typical failure modes were also acquired. Results indicated that with increasing nc and v0, and decreasing λ, the conventional CFRP-SHSCMs were prone to local bearing failure with poor ductility, leading to the insufficient use of the CFRP plate, in contrast, the improved CFRP-SHSCMs primarily underwent overall buckling failure and exhibited better bearing force and ductility. Finally, the modified Perry-Robertson formula was put forward to predict the ultimate load of the CFRP-SHSCMs. The coefficients of variation between the FE simulation and the theoretical results were 0.00436 and 0.0292, respectively.

3.
Materials (Basel) ; 16(8)2023 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-37109811

RESUMO

This work reports the investigations of the electric potential impacts on the mechanical buckling of the piezoelectric nanocomposite doubly curved shallow shells reinforced by functionally gradient graphene platelets (FGGPLs). A four-variable shear deformation shell theory is utilized to describe the components of displacement. The present nanocomposite shells are presumed to be rested on an elastic foundation and subject to electric potential and in-plane compressive loads. These shells are composed of several bonded layers. Each layer is composed of piezoelectric materials strengthened by uniformly distributed GPLs. The Halpin-Tsai model is employed to calculate the Young's modulus of each layer, whereas Poisson's ratio, mass density, and piezoelectric coefficients are evaluated based on the mixture rule. The graphene components are graded from one layer to another according to four different piecewise laws. The stability differential equations are deduced based on the principle of virtual work. To test the validity of this work, the current mechanical buckling load is analogized with that available in the literature. Several parametric investigations have been performed to demonstrate the effects of the shell geometry elastic foundation stiffness, GPL volume fraction, and external electric voltage on the mechanical buckling load of the GPLs/piezoelectric nanocomposite doubly curved shallow shells. It is found that the buckling load of GPLs/piezoelectric nanocomposite doubly curved shallow shells without elastic foundations is reduced by increasing the external electric voltage. Moreover, by increasing the elastic foundation stiffness, the shell strength is enhanced, leading to an increase in the critical buckling load.

4.
Materials (Basel) ; 16(4)2023 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-36836983

RESUMO

Bamboo is a natural material with the potential for being used in sustainable construction. However, uncertainty in the bearing capacity of the bamboo results in nonstandard values for structural engineering design. This research studied the simple and multiple linear regression analyses for indicating properties to predict the axial compressive load capacity and strength of bamboo culms, which will be useful information for quality control during building construction and further structural grading. First, twelve basic physical properties were measured from 111 samples of Dendrocalamus sericeus Munro bamboo culms, and axial compressive load tests of the bamboo culms were performed. Then, the correlation significance of the physical properties to axial load capacity and strength (load per area) were analyzed by the Pearson correlation method. The results show that five parameters, i.e., linear mass, culm wall thickness, external diameter, moisture content, and density, were statistically significant with the responses (compressive load capacity and compressive strength) and then defined as "candidates for indicating properties". Next, simple linear and multiple linear regression were analyzed to formulate the relationship between the significant indicating properties and the responses. From the simple linear regression analysis, linear mass can be best used as an indicating property for predicting the maximum compressive load. The maximum compressive strength was well associated with density. The multiple linear regression analysis shows an improvement in the response predictions with respect to the simple linear regression analysis with the higher R2-values. Finally, structural grading of the bamboo is determined.

5.
Scand J Med Sci Sports ; 33(5): 619-630, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36517927

RESUMO

Mechanical overload is considered the main cause of Achilles tendinopathy. In addition to tensile loads, it is believed that the Achilles tendon may also be exposed to compressive loads. However, data on intratendinous pressures are lacking, and consequently, their role in the pathophysiology of tendinopathy is still under debate. Therefore, we aimed to evaluate the intratendinous pressure changes in the Achilles tendon during stretching and eccentric loading. Twelve pairs of human cadaveric legs were mounted in a testing rig, and a miniature pressure catheter was placed through ultrasound-guided insertion in four different regions of the Achilles tendon: the insertion (superficial and deep layers), mid-portion, and proximal portion. Intratendinous pressure was measured during three simulated loading conditions: a bent-knee calf stretch, a straight-knee calf stretch, and an eccentric heel-drop. It was found that the intratendinous pressure increased exponentially in both the insertion and mid-portion regions of the Achilles tendon during each loading condition (p < 0.001). The highest pressures were consistently found in the deep insertion region (p < 0.001) and during the eccentric heel-drop (p < 0.001). Pressures in the mid-portion were also significantly higher than in the proximal portion (p < 0.001). These observations offer novel insights and support a role for compression in the pathophysiology of Achilles tendinopathy by demonstrating high intratendinous pressures at regions where Achilles tendinopathy typically occurs. To what extent managing intratendinous pressure might be successful in patients with Achilles tendinopathy by, for example, avoiding excessive stretching, modifying exercise therapy, and offering heel lifts requires further investigation.


Assuntos
Tendão do Calcâneo , Tendinopatia , Humanos , Tendão do Calcâneo/fisiologia , Calcanhar , Terapia por Exercício , Pressão
6.
Stem Cells Dev ; 31(15-16): 460-487, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35615879

RESUMO

Chondrogenesis is the process of differentiation of stem cells into mature chondrocytes. Such a process consists of chemical, functional, and structural changes which are initiated and mediated by the host environment of the cells. To date, the mechanobiology of chondrogenesis has not been fully elucidated. Hence, experimental activity is focused on recreating specific environmental conditions for stimulating chondrogenesis and to look for a mechanistic interpretation of the mechanobiological response of cells in the cartilaginous tissues. There are a large number of studies on the topic that vary considerably in their experimental protocols used for providing environmental cues to cells for differentiation, making generalizable conclusions difficult to ascertain. The main objective of this contribution is to review the mechanobiological stimulation of stem cell chondrogenesis and methodological approaches utilized to date to promote chondrogenesis of stem cells in vitro. In vivo models will also be explored, but this area is currently limited. An overview of the experimental approaches used by different research groups may help the development of unified testing methods that could be used to overcome existing knowledge gaps, leading to an accelerated translation of experimental findings to clinical practice.


Assuntos
Condrogênese , Células-Tronco , Biofísica , Cartilagem , Diferenciação Celular , Células Cultivadas , Condrócitos , Condrogênese/fisiologia
7.
Materials (Basel) ; 14(16)2021 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-34442954

RESUMO

In bone tissue engineering, the design of in vitro models able to recreate both the chemical composition, the structural architecture, and the overall mechanical environment of the native tissue is still often neglected. In this study, we apply a bioreactor system where human bone-marrow hMSCs are seeded in human femoral head-derived decellularized bone scaffolds and subjected to dynamic culture, i.e., shear stress induced by continuous cell culture medium perfusion at 1.7 mL/min flow rate and compressive stress by 10% uniaxial load at 1 Hz for 1 h per day. In silico modeling revealed that continuous medium flow generates a mean shear stress of 8.5 mPa sensed by hMSCs seeded on 3D bone scaffolds. Experimentally, both dynamic conditions improved cell repopulation within the scaffold and boosted ECM production compared with static controls. Early response of hMSCs to mechanical stimuli comprises evident cell shape changes and stronger integrin-mediated adhesion to the matrix. Stress-induced Col6 and SPP1 gene expression suggests an early hMSC commitment towards osteogenic lineage independent of Runx2 signaling. This study provides a foundation for exploring the early effects of external mechanical stimuli on hMSC behavior in a biologically meaningful in vitro environment, opening new opportunities to study bone development, remodeling, and pathologies.

8.
Eur J Oral Sci ; 129(6): e12818, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34289176

RESUMO

The aim of the study was to compare the response of calvarial and femoral osteoblasts cultured in a 3D hydrogel environment to cyclic compressive mechanical loading. Human foetal femoral and calvarial osteoblasts were encapsulated in a semi-synthetic thiol-modified hyaluronan gelatin polyethylene glycol diacrylate (PEGDA) cross-linked HyStemC hydrogel. Constructs were subjected to a cyclic compressive strain of 33.4 kPa force every second for 5 s every hour for 6 h per day using FlexCell BioPress culture plates and compared to non-compressed constructs. Cell viability, mineralisation, and morphological changes were observed over 21 days. BMP2, ALP, COL1A1, COL2A1, and OCN gene expression levels were quantified. Encapsulated osteoblast numbers increased and formed hydroxyapatite over a 21-day period. Cell viability decreased under a cyclical strain when compared to cells under no strain. Femoral osteoblasts under strain expressed increased levels of BMP2 (53.9-fold) and COL1A1 (5.1-fold) mRNA compared to no strain constructs. Surprisingly, no BMP2 mRNA was detected in calvarial osteoblasts. Osteoblasts derived from endochondral (femoral) and intra-membranous (calvarial) processes behaved differently in 3D-constructs. We therefore recommend that site-specific osteoblasts be used for future bone engineering and bone replacement materials and further research undertaken to elucidate how site-specific osteoblasts respond to cyclic compressive loads.


Assuntos
Fêmur , Osteoblastos , Durapatita , Expressão Gênica , Humanos , Estresse Mecânico
9.
Technol Health Care ; 29(6): 1161-1171, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33998567

RESUMO

BACKGROUND: The aesthetics and strength of anterior porcelain layered zirconia (PLZ) crowns are mainly affected by the zirconia (Zr) coping design. There is a need for a modified design to enhance aesthetics with strength. OBJECTIVES: The purpose of this study was to compare the fracture resistance of anterior PLZ crowns having modified CAD-CAM Zr coping designs (in terms of thickness and marginal collar designs) with standard Zr copings. METHODS: Fifty PLZ crowns were fabricated and divided into two groups: Gr 1: Standard Zr Coping (SZC) (control gr) with 0.5 mm thickness (Facial-F, Mesial-M, Distal-D, incisal-I, and Palatal-P) without a collar; Gr 2: Collar Zr Coping (CZC) (test gr) with 2.5 mm collar height on M, D, P and 0.2 mm F and variable facial wall thickness. Subgroups: Gr 2a: (CZC-0.5 mm) facial wall thickness 0.5 mm; Gr 2b: (CZC-0.4 mm) facial wall thickness 0.4 mm; Gr 2c: (CZC-0.3 mm) facial wall thickness 0.3 mm; Gr 2d: (CZC-0.2 mm) facial wall thickness 0.2 mm. The fracture load was determined and analysed using One-way ANOVA and Dunnet test. RESULTS: The minimum fracture load was 927.36 ± 127.80 N observed for Gr 2c (CZC at 0.3 mm) while the maximum fracture load was 1373.61 ± 146.54 N observed for Gr 2a (CZC at 0.5 mm). A highly significant difference in mean fracture load among various Zr coping groups (p< 0.001) was determined. CONCLUSIONS: Novel Zr coping design for anterior PLZ crowns can provide better aesthetics with strength. Reducing the thickness of Zr coping in the aesthetic zone to 0.2 mm and providing a modified collar design (2.5 mm collar height on M, D, P, and 0.2 mm F) would provide strength without jeopardizing aesthetics.


Assuntos
Desenho Assistido por Computador , Zircônio , Adaptação Psicológica , Porcelana Dentária , Estética , Humanos , Teste de Materiais
10.
Knee Surg Sports Traumatol Arthrosc ; 29(2): 342-351, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32152692

RESUMO

PURPOSE: To compare the effect of the lateral meniscus (LM) complete radial tear at different tear sites on the load distribution and transmission functions. METHODS: A compressive load of 300 N was applied to the intact porcine knees (n = 30) at 15°, 30°, 60°, 90°, and 120° of flexion. The LM complete radial tears were created at the middle portion (group M), the posterior portion (group P), or the posterior root (group R) (n = 10, each group), and the same loading procedure was followed. Finally, the recorded three-dimensional paths were reproduced on the LM-removed knees. The peak contact pressure (contact area) in the lateral compartment and the calculated in situ force of the LM under the principle of superposition were compared among the four groups (intact, group M, group P, and group R). RESULTS: At all the flexion angles, the peak contact pressure (contact area) was significantly higher (lower) after creating the LM complete radial tear as compared to that in the intact state (p < 0.01). At 120° of flexion, group R represented the highest peak contact pressure (lowest contact area), followed by group P and group M (p < 0.05). The results of the in situ force carried by the LM were similar to those of the tibiofemoral contact mechanics. CONCLUSION: The detrimental effect of the LM complete radial tear on the load distribution and transmission functions was greatest in the posterior root tear, followed by the posterior portion tear and the middle portion tear in the deep-flexed position. Complete radial tars of the meniscus, especially at the posterior root, should be repaired to restore the biomechanical function.


Assuntos
Traumatismos do Joelho/fisiopatologia , Meniscos Tibiais/fisiopatologia , Lesões do Menisco Tibial/fisiopatologia , Animais , Fenômenos Biomecânicos , Humanos , Articulação do Joelho/fisiopatologia , Pessoa de Meia-Idade , Pressão , Amplitude de Movimento Articular , Estresse Mecânico , Suínos , Suporte de Carga
11.
J Orthop Res ; 39(9): 1945-1954, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33073417

RESUMO

Many factors contribute to the development and progression of intervertebral disc (IVD) degeneration. This study was designed to assess the effects of compressive load magnitude on IVD metabolism. It was hypothesized that as load magnitude increased, there would be a significant increase in release of proinflammatory and degradative biomarkers, and a significant decrease in tissue proteoglycan (GAG) and collagen contents compared with unloaded controls. IVD whole organ functional spinal units (FSU) consisting of cranial and caudal body halves, cartilage endplates, and IVD (n = 36) were harvested from the tails of six Sprague Dawley rats, and FSUs were cultured at 0.0 MPa, 0.5 MPa, or 1.0 MPa at 0.5 Hz for 3 days. After culture, media were collected for biomarker analysis and FSUs were analyzed for extracellular matrix composition. Significant differences were determined using a one-way analysis of variance or Kruskal-Wallis test and post hoc analyses. Media concentrations of IFN-γ, IL-6, IL-1ß, and MMP-8 were significantly higher in the 0.5 MPa compared with the 0.0 MPa group. Media concentrations of PGE2 and TIMP-1 were significantly higher in the 1.0 MPa group compared with the 0.0 MPa group, and media PGE2 was significantly higher in the 1.0 MPa group compared with the 0.5 MPa group. Media GAG content was significantly higher in the 1.0 MPa group compared with the 0.0 MPa group, and percent GAG in the tissue was significantly lower in 0.5 MPa and 1.0 MPa groups compared with the 0.0 MPa group. Clinical Significance: These data suggest that there are magnitude-dependent inflammatory and degradative IVD responses to cyclic loading, which may contribute to IVD degeneration.


Assuntos
Degeneração do Disco Intervertebral , Disco Intervertebral , Animais , Cartilagem/metabolismo , Dinoprostona/metabolismo , Disco Intervertebral/metabolismo , Degeneração do Disco Intervertebral/metabolismo , Ratos , Ratos Sprague-Dawley
12.
J Biomech ; 98: 109437, 2020 01 02.
Artigo em Inglês | MEDLINE | ID: mdl-31679758

RESUMO

Most of the current rigid-body models of the complete thoracolumbar spine do not properly model the intervertebral joint as the highly nonlinear stiffness is not incorporated comprehensively and the effects of compressive load on stiffness is commonly being neglected. Based on published in vitro data of individual intervertebral joint flexibility, multi-level six degree-of-freedom nonlinear stiffness of functional spinal units was modelled and incorporated in a rigid-body model of the thoracolumbar spine. To estimate physiological in vivo conditions of the entire spine, stiffening effects caused by directly applied compressive loads, and contributions to mono-segmental stiffness from the rib cage as well as multi-segmental interactions in the thoracic spine were analysed and implemented. Forward dynamic simulations were performed to simulate in vitro tests that measured the load-displacement response of the spine under various loading conditions. The predicted kinematic responses of the model were in agreement with in vitro measurements, with correlations between simulated and measured segmental displacements varying between 0.66 and 0.97 (p < 0.05) and average deviations below 1.6°. Coupling relationships were found between lateral bending and axial rotation. Under compressive loads, the model behaved stiffer and showed a decreased range of motion: The flexion/extension response of the full thoracolumbar spine under compressive loads up to 800 N was found to strongly correlate with the literature (r = 0.99, p < 0.0001). The implementation of physiological functional spinal units with nonlinear stiffness properties into rigid-body models can enhance accuracy of biomechanical simulations, and enable detailed analysis of spinal kinematics under complex loading conditions seen in vivo.


Assuntos
Vértebras Lombares/fisiologia , Fenômenos Mecânicos , Vértebras Torácicas/fisiologia , Fenômenos Biomecânicos , Cadáver , Força Compressiva , Humanos , Pressão , Amplitude de Movimento Articular/fisiologia , Caixa Torácica , Rotação , Suporte de Carga
13.
Materials (Basel) ; 12(16)2019 Aug 08.
Artigo em Inglês | MEDLINE | ID: mdl-31398882

RESUMO

This study focuses on the effect generated by a compressive load, in the range 15%-60% of the ultimate load (Fu), in the chloride penetration rate of cement-based materials. The modifications produced in the microstructure influence the transport properties, and, thus, the validation of several interesting parameters, such as, the load value and the loading time, including both static and dynamic loading modes, was evaluated. This analysis was performed by impedance spectroscopy (IS), a non-destructive technique that allowed, after the appropriate modeling analysis, the assessment of the resistivity of the sample, a parameter that has been correlated to the diffusion coefficient in a previous investigation. The experimental arrangement was designed to allow the recording of the impedance spectra under the effect of a compressive load and, thus, the real-time monitoring of the chloride diffusivity was provided. An increase in the diffusion coefficient was verified for a load at 60%Fu whereas no variations were obtained for the load fixed at 30%. A relevant difference could be checked if the values were measured once the load was removed, showing the importance of the precise loading stage for the chloride diffusion study.

14.
Nanomaterials (Basel) ; 9(4)2019 Apr 10.
Artigo em Inglês | MEDLINE | ID: mdl-30974888

RESUMO

Carbon nanofibers (CNFs) were directly synthesized on Portland cement particles by chemical vapor deposition. The so-produced cements contained between 2.51-2.71 wt% of CNFs; depending on the production batch. Several mortar mixes containing between 0 and 10 wt% of the modified cement were produced and the electrical properties at various ages and the load sensing capabilities determined. The percolation threshold related to the electrical conductivity was detected and corresponded to the amount of the present CNFs, 0.271, 0.189, 0.135 and 0.108 wt%. The observed threshold depended on the degree of hydration of the Portland cement. The studied mortars showed a strong piezoresistive response to the applied compressive load reaching a 17% change of the electrical resistivity at an applied load of 3.5 MPa and 90% at 26 MPa. This initial study showed that the studied material is potentially suitable for future development of novel fully integrated monitoring systems for concrete structures.

15.
Materials (Basel) ; 12(7)2019 Mar 29.
Artigo em Inglês | MEDLINE | ID: mdl-30934831

RESUMO

We have studied an application of the Voronoi tessellation method in the modeling of open-cell aluminium foam under uniaxial compressive loading. The Voronoi code was merged with computer-aided design (CAD) for converting the polyhedral model into an irregular open-cell cellular structure to create porous samples for compression testing simulations. Numerical simulations of the uniaxial compression uniformly over the upper surface of the sample in the z-axis direction at a constant 20 N load was realised. Samples with three different porosities (30%, 60% and 80%) were studied. A nonlinear elasto-plastic material model with perfect plasticity, without hardening, based on the von Mises yield criterion was applied below 10% strain. Corresponding stress⁻strain curves were observed and the influence of porosity on deformation mechanism was discussed. Samples with higher porosity exhibited significantly higher normal stress under the same load, and increased stress plateaus. An increase of porosity produced an increase of both compressive and tensile stresses and struts exhibited complex stress fields. Voronoi-based modeling was in accordance with experimental results in the literature in the case of the quasi-static condition and linear elastic region (below 1% strain). Further study is necessary to enable the simulation of real dynamic behaviour under all deformation regimes by using the Voronoi tessellation method.

16.
J Orthop Res ; 36(7): 1901-1909, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29393547

RESUMO

Pre-clinical assessment of stability in total knee replacement is crucial for developing preferred implant performance. Current total knee replacement patients often experience joint instability that the human body addresses with compensatory strategies. Specifically, an increased quadriceps-hamstrings co-contraction serves to increase joint stability through an increased compressive force across the tibiofemoral joint. The aim of this study is to introduce a novel method to evaluate total knee replacement by determining the compressive loading required to achieve natural knee stability. Four current total knee replacement geometries in both their cruciate-retaining and posterior-stabilized forms are modeled in a finite-element framework. The finite-element model is initially validated experimentally using traditional knee laxity testing with a constant compressive load and anterior-posterior displacement or internal-external rotation. Model predictions of constraint are in reasonable agreement with experimental results (average root mean square errors: 0.46 Nm, 62.5 N). The finite-element model is subsequently interfaced with a feedback controller to vary the compressive force that the implant requires in order to match experimental natural knee internal-external and anterior-posterior stability at different flexion angles. Results show that the lower constraint total knee replacement designs require on average 66.7% more compressive load than the higher constraint designs to achieve natural knee constraint. As expected, total knee replacement stability and compressive load requirements to replicate natural kinematics vary with inclusion of tibiofemoral ligaments. The current study represents a novel approach to evaluate stability in existing total knee replacement geometries and to design implants that better restore natural knee mechanics. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1901-1909, 2018.


Assuntos
Artroplastia do Joelho/métodos , Força Compressiva , Simulação por Computador , Retroalimentação , Fenômenos Biomecânicos , Eletromiografia , Análise de Elementos Finitos , Humanos , Joelho/anatomia & histologia , Joelho/fisiologia , Articulação do Joelho/cirurgia , Prótese do Joelho , Movimento (Física) , Amplitude de Movimento Articular , Tíbia/cirurgia , Torque
17.
J Mot Behav ; 50(6): 631-642, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29140761

RESUMO

We investigated the effects of vertical vibration and compressive load on soleus H-reflex amplitude and postactivation depression. We hypothesized that, in the presence of a compressive load, limb vibration induces a longer suppression of soleus H-reflex. Eleven healthy adults received vibratory stimulation at a fixed frequency (30 Hz) over two loading conditions (0% and 50% of individual's body weight). H-reflex amplitude was depressed ∼88% in both conditions during vibration. Cyclic application of compression after cessation of the vibration caused a persistent reduction in H-reflex excitability and postactivation depression for > 2.5 min. A combination of limb segment vibration and compression may offer a nonpharmacologic method to modulate spinal reflex excitability in people after CNS injury.


Assuntos
Extremidades/fisiologia , Reflexo H/fisiologia , Músculo Esquelético/fisiologia , Adulto , Eletromiografia , Feminino , Humanos , Masculino , Vibração , Suporte de Carga/fisiologia , Adulto Jovem
18.
J Dent ; 59: 54-61, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28214537

RESUMO

OBJECTIVES: To evaluate the effect of restoration design ('2.5-mm deep endocrown', '5-mm deep endocrown' or '5-mm deep post&crown') and CAD/CAM material type (composite or lithium disilicate glass-ceramic) on the load-to-failure of endodontically treated premolars in absence of any ferrule. METHODS: The crowns of 48 single-rooted premolars were cut and the roots were endodontically treated. Teeth were randomly divided into six groups (n=8); teeth in each group were restored using one of the two tested materials with standardized CAD/CAM fabricated endocrowns (with either 2.5-mm or 5-mm deep intra-radicular extension) or conventional crowns (5-mm deep post&crown). After cementation using luting composite, the specimens were immersed in distilled water and subjected to 1,200,000 chewing cycles with a load of 50N applied parallel to the long axis of the tooth (0°). After cyclic loading, a compressive load was applied at 45° to the tooth's long axis using a universal testing machine until failure. Load-to-failure was recorded (N) and the specimens were examined under a stereomicroscope with 3.5x magnification to determine the mode of failure. RESULTS: All specimens survived the 1,200,000 chewing cycles. A significant interaction between restoration design and CAD/CAM material was found using two-way ANOVA. In the '2.5-mm deep endocrown' groups, the composite achieved a significantly higher load-to-failure than the lithium disilicate glass-ceramic, while no differences between materials were found in the '5-mm deep endocrown' and '5-mm deep post&crown' groups. More unfavorable failures (root fractures) were observed for higher load-to-failure values. CONCLUSIONS: Only following a '2.5-mm deep endocrown' design, composite appeared more favorable than lithium disilicate glass-ceramic as crown material; this may be explained by their difference in elastic modulus. CLINICAL SIGNIFICANCE: Shallow endocrown preparations on premolars present less surface for adhesive luting and a difference in crown material becomes apparent in terms of load-to-failure. The use of a more flexible composite crown material appeared then a better option.


Assuntos
Dente Pré-Molar , Materiais Biomédicos e Odontológicos , Desenho Assistido por Computador , Coroas , Porcelana Dentária/química , Planejamento de Prótese Dentária , Dente não Vital , Cimentação , Cerâmica/química , Força Compressiva , Falha de Restauração Dentária , Análise do Estresse Dentário , Humanos , Teste de Materiais , Estresse Mecânico
19.
Journal of Medical Biomechanics ; (6): 130-136, 2017.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-614564

RESUMO

Objective To study the damage propagation and evolution mechanism of cartilage under compressive loads.Methods The fiber-reinforced porous elastic model of cartilage with micro-defect was established by using finite element method,and the process of damage evolution under compressive loads was simulated and analyzed with parameters.The patterns of stress and strain distributions on cartilage matrix and collagen fiber at different damage extension stages were obtained.Results The strain in the surface and forefront of cartilage damage increased significantly with the increase of compression displacement,and they were obviously in positive correlation;in the process of damage evolution,there was a trend that cartilage extended to the deep and both sides simultaneously;cracks and damage in cartilage extended preferentially along the fiber tangent direction.With the aggravation of cartilage damage,the lateral extension speed was significantly faster than the longitudinal extension speed.Conclusions The process of cartilage damage extension has a close relationship with the distribution of fibers.The damages in matrix and fiber promote each other.The evolution speed and degree of cartilage vary constantly in different layers and at different stages.These results can provide the qualitative reference for prediction and repair of cartilage damage,as well as the theoretical basis for explaining pathological phenomena of damage degeneration and its clinic treatment.

20.
Journal of Medical Biomechanics ; (6): 130-136, 2017.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-735846

RESUMO

Objective To study the damage propagation and evolution mechanism of cartilage under compressive loads.Methods The fiber-reinforced porous elastic model of cartilage with micro-defect was established by using finite element method,and the process of damage evolution under compressive loads was simulated and analyzed with parameters.The patterns of stress and strain distributions on cartilage matrix and collagen fiber at different damage extension stages were obtained.Results The strain in the surface and forefront of cartilage damage increased significantly with the increase of compression displacement,and they were obviously in positive correlation;in the process of damage evolution,there was a trend that cartilage extended to the deep and both sides simultaneously;cracks and damage in cartilage extended preferentially along the fiber tangent direction.With the aggravation of cartilage damage,the lateral extension speed was significantly faster than the longitudinal extension speed.Conclusions The process of cartilage damage extension has a close relationship with the distribution of fibers.The damages in matrix and fiber promote each other.The evolution speed and degree of cartilage vary constantly in different layers and at different stages.These results can provide the qualitative reference for prediction and repair of cartilage damage,as well as the theoretical basis for explaining pathological phenomena of damage degeneration and its clinic treatment.

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