Removal of graffiti paint from construction materials coated with TiO2-based photocatalysts.

Graffiti on construction materials has significant social and economic impacts, especially on artistic and historical artefacts. Anti-graffiti protective coatings are used to generate low surface energies that limit graffiti adhesion to the surface, thereby reducing surface damage and facilitating removal. The anti-graffiti properties of three commercial TiO2-based coatings were tested under outdoor exposure conditions using four colours of graffiti paint (red, blue, black, and white). Chemical removers were used to clean the stained surfaces to understand the impact of the photocatalytic coatings during the conventional cleaning procedure. The effectiveness of cleaning was assessed by visual observations, colour measurements, and the percentage of residual stain. The anti-graffiti efficacy was strongly dependent on the colour of the graffiti and characteristics of the TiO2 coating. The cleaning performance of TiO2-treated samples was likely related to the photocatalytic redox reactions that decompose the graffiti. Additionally, their hydrophilicity may also prevent the adhesion and/or penetration of graffiti paint on the surface and/or pore matrix.

Exploring prognostic DNA methylation genes in bladder cancer: a comprehensive analysis.

The current study aimed to investigate the status of genes with prognostic DNA methylation sites in bladder cancer (BLCA). We obtained bulk transcriptome sequencing data, methylation data, and single-cell sequencing data of BLCA from public databases. Initially, Cox survival analysis was conducted for each methylation site, and genes with more than 10 methylation sites demonstrating prognostic significance were identified to form the BLCA prognostic methylation gene set. Subsequently, the intersection of marker genes associated with epithelial cells in single-cell sequencing analysis was obtained to acquire epithelial cell prognostic methylation genes. Utilizing ten machine learning algorithms for multiple combinations, we selected key genes (METRNL, SYT8, COL18A1, TAP1, MEST, AHNAK, RPP21, AKAP13, RNH1) based on the C-index from multiple validation sets. Single-factor and multi-factor Cox analyses were conducted incorporating clinical characteristics and model genes to identify independent prognostic factors (AHNAK, RNH1, TAP1, Age, and Stage) for constructing a Nomogram model, which was validated for its good diagnostic efficacy, prognostic prediction ability, and clinical decision-making benefits. Expression patterns of model genes varied among different clinical features. Seven immune cell infiltration prediction algorithms were used to assess the correlation between immune cell scores and Nomogram scores. Finally, drug sensitivity analysis of Nomogram model genes was conducted based on the CMap database, followed by molecular docking experiments. Our research offers a reference and theoretical basis for prognostic evaluation, drug selection, and understanding the impact of DNA methylation changes on the prognosis of BLCA.

Axiomatic design for safe construction considering lean and ergonomic principles: an application in Turkey.

This study proposes a systematic approach based on axiomatic design incorporating lean and ergonomic principles within the proposed design. The contribution to the body of knowledge is to keep construction workers safe by fostering a secure construction environment. Axiomatic design and lean approaches are combined to address human factors and eliminate wastes that hinder a safe construction environment. The application of the proposed system is set in the context of the construction industry. The methodology provides the construction sector with a road map toward reducing the occurrence of accidents and serves as a complementary approach between lean and ergonomic principles. The design solution has been validated and partially applied in a metro construction firm. Results show that the design solution can improve the efficiency of the construction phases by adopting a value-maximization strategy and has the potential to improve the safety and ergonomics of construction projects.

Scene construction processes in the anterior hippocampus during temporal episodic memory retrieval.

Although the hippocampus has been implicated in both the temporal organization of memories and association of scene elements, some theoretical accounts posit that the role of the hippocampus in episodic memory is largely atemporal. In this study, we set out to explore this discrepancy by identifying hippocampal activity patterns related to scene construction while participants performed a temporal order memory task. Participants in the fMRI scanner were shown a sequence of photographs, each consisting of a central object and a contextual background scene. On each retrieval trial, participants were shown a pair of the original photographs (FULL), objects from the scenes without the background (OBJ), or background contexts without the main foreground object (BACK). In the temporal order judgment (TOJ) task, participants judged the temporal order of the pair of scenes; in the Viewing trials, two identical scenes were shown without any task. First, we found that the anterior hippocampus-particularly the CA1 and subiculum-showed similar patterns of activation between the BACK and OBJ conditions, suggesting that scene construction occurred spontaneously during both TOJ and Viewing. Furthermore, neural markers of scene construction in the anterior hippocampus did not apply to incorrect trials, showing that successful temporal memory retrieval was functionally linked to scene construction. In the cortex, time-processing areas, such as the supplementary motor area and the precuneus, and scene-processing areas, such as the parahippocampal cortex, were activated and functionally connected with the hippocampus. Together, these results support the view that the hippocampus is concurrently involved in scene construction and temporal organization of memory and propose a model of hippocampal episodic memory that takes both processes into account.

An eco-friendly solution for construction and demolition waste: Recycled coarse aggregate with CO2 utilization.

Carbonation of recycled coarse aggregate (RCA) is an eco-friendly solution for the recycling of construction and demolition waste. This paper provides a comprehensive understanding of utilizing CO2 in RCA. The carbonation mechanism associated with CO2 treatment of RCA has been systematically summarized. The methods for CO2 treatment of RCA and the calculation of CO2 sequestration were discussed. Meanwhile, the efficiency of physical properties enhancement of carbonized RCA was analyzed. The microstructure, mechanical properties and durability improvement of recycled concrete containing carbonized RCA were reviewed. Additionally, the environmental benefits of carbonized RCA were provided through carbon footprint, carbon accounting and carbon intensity. Furthermore, the future perspectives of RCA with CO2 utilization were prospected.

Using olfactory cues in text materials benefits delayed retention and schemata construction.

Olfactory cues are considered a new sensory medium that can enhance learning, but the lack of empirical data has hampered their widespread use in educational practice. This requires empirical research to explore the effects of olfactory cues on learning. To address this research need, an experimental research study was conducted among 87 fourth graders from a Chinese elementary school. It explored the innovative design of adding olfactory cues to text materials by examining their effects on retention and schemata construction as learning outcomes, as well as their influence on learners' cognitive load and learning experience. In this between-subjects design experiment, the experimental group (n = 44) learned text materials with the introduction of olfactory cues, while the control group (n = 43) only learned text materials. After the learning activity, participants were asked to complete the questionnaires, immediate test, and delayed test. The results revealed that the usage of olfactory cues synchronized with text materials can enhance delayed retention, facilitate schemata construction, and improve learner experience without increasing cognitive load. This study confirms the potential of well-designed olfactory cues in educational practice and provides insights for designing and presenting multimedia learning resources.

Can the natural resource balance sheet system promote ecological civilization? --Empirical evidence from panel data of prefecture-level cities in China.

As a crucial carrier of natural resource and environmental information, the natural resources balance sheet is important in enhancing ecological governance capabilities and advancing ecological civilization construction. Utilizing panel data from Chinese prefecture cities spanning 2012 to 2018, we employ a Difference-in-Differences (DID) model to examine the policy effects of the natural resources balance sheet system. The findings indicate that compiling the natural resources balance sheet significantly promotes local ecological civilization construction, and local government environmental governance efficiency partially mediates this relationship. Further analysis indicates that the outgoing audit of natural resources and public environmental concern positively moderates the relationship between the two. Drawing on the principal-agent theory, we provide in-depth analysis and elucidation of the mechanisms through which the natural resources balance sheet promotes ecological civilization construction, offering theoretical guidance and empirical data support for strengthening the compilation and application of the natural resources balance sheet.

Modelling constructivist language acquisition through syntactico-semantic pattern finding.

The constructivist acquisition of language by children has been elaborately documented by researchers in psycholinguistics and cognitive science. However, despite the centrality of human-like communication in the field of artificial intelligence, no faithful computational operationalizations of the mechanisms through which children learn language exist to date. In this article, we fill part of this void by introducing a mechanistic model of the constructivist acquisition of language through syntactico-semantic pattern finding. Concretely, we present a methodology for learning grammars based on similarities and differences in the form and meaning of linguistic observations alone. The resulting grammars consist of form-meaning mappings of variable extent and degree of abstraction, called constructions, which facilitate both language comprehension and production. Applying our methodology to the CLEVR benchmark dataset, we provide a proof of concept that demonstrates the online, incremental, data-efficient, transparent and effective learning of item-based construction grammars from utterance-meaning pairs.

Promoting Surface Reconstruction in Spinel Oxides via Tetrahedral-Octahedral Phase Boundary Construction for Efficient Oxygen Evolution.

Understanding the origin of surface reconstruction is crucial for developing highly efficient lattice oxygen oxidation mechanism (LOM) based spinel oxides. Traditionally, the reconstruction has been achieved through electrochemical procedures, such as cyclic voltammetry (CV), linear sweep voltammetry (LSV). In this work, we found that the surface reconstruction in LOM-based CoFe0.25Al1.75O4 catalyst was an irreversible oxygen redox chemical reaction. And a lower oxygen vacancy formation energy (EO-V) could benefit the combination of the activated lattice oxygen atoms with adsorbed water molecular. Motivated by this finding, a strategy of phase boundary construction from Co tetrahedral to octahedral was employed to decrease EO-V in CoFe0.25Al1.75O4. The results showed that as the Co octahedral occupancy ratio rose to 64%, a 3.5 nm-thick reconstructed layer formed on the catalyst surface with a 158 mV decrease in overpotential. Further experiments indicated that the coexistence of tetrahedral-octahedral (O-T) phase would result in lattice mismatch, promoting non-bonding oxygen states and lowering EO-V. Then more active lattice oxygen combined with H2O molecules to generate hydroxide ions (OH-), followed by soluble cation leaching, which enhanced the reconstruction process. This work provided new insights into the relationship between the intrinsic structure of pre-catalysts and surface reconstruction in LOM-based spinel electrocatalysts.

What type of social media posts about sustainable construction is better for audience engagement?

Background: In an effort to move to a sustainable society, new concepts and findings related to sustainable construction are being developed. With ambition to transfer newly developed knowledge to society, various communication paths are being used. In this study we investigated what kind of messages shared on institutional social media channels (Facebook, Twitter (now renamed to X), and LinkedIn) about sustainable construction create more audience engagement. Methods: The study consisted of two phases of weekly social media posts. In each phase, 15 posts were published on the same day and time, while engagement was monitored. Three different types of posts were created, that were sequential cycling each week. Type 1 was written informative content related to research activities; type 2 was image content related to the research activities and equipment, with a short text caption of the image; and type 3 was image content with people - scientists working on research activities with a short text caption of the image. Results: Poisson regression analysis revealed that type 3 posts result in the most audience engagement on LinkedIn, suggesting that using images of people in combination with short text captions is the most effective way to engage social media audiences. These findings can help organizations to use social media to promote sustainable construction and other sustainability-related research. The engagement was lower on Facebook and Twitter (X). Conclusions: As the science is aiming to be closer to the society, these findings deliver an important insight of science communication through the social media. Although the study delivered several lessons learnt related to science communication through social media studies, it provides an important bases for further studies. Conclusions can support research organizations in improving their science communication.

Compliance of private ventilated improved pit latrines to odour and fly control guidelines: A technical audit in selected regions of Ghana.

The ventilated improved pit (VIP) latrine offers a promising route to safely managed sanitation to many households in developing countries. However, some technical guidelines must be followed in order to realise the technology's advantage of odour and fly nuisance control. This study sought to audit private VIP latrines in selected regions of Ghana to assess their compliance to conventional technical guidelines and to understand the major factors that influence the latrine designs. An inspection checklist was developed to assess 296 private VIP latrines in the Central, Ashanti and Northern Regions of Ghana while semi-structured interviews were conducted among the latrine owners to enquire the factors that influenced the designs of their latrines. The results show that provision of a window in the superstructure (86 %), and the avoidance of an insect screen in the window(s) (77 %) were the most complied guidelines. The use of 150 mm diameter vent pipe was the least satisfied guideline (5 %). On the average, a latrine satisfied about half (3.6) of the technical guidelines that were assessed. The decision or advice of local artisans is the most influential factor in the design of the latrines. Cost was the least mentioned factor cited by the latrine owners. There is the need to establish information desks at the various Metropolitan, Municipal and District Assemblies (MMDAs) to guide prospective owners on the proper design and construction of the VIP latrine. In addition, toilet construction should be incorporated in the curriculum for the basic training of building and construction students in Technical and Vocational Education and Training (TVET) institutions in Ghana. Further research is required to ascertain the basis of the decisions of local artisans and the potential impact of the use of accessories that are 'borrowed' from the WC toilet on odour and fly control in the latrine.

Recent advances in MOF-based nanozymes: Synthesis, activities, and bioapplications.

Nanozymes have garnered considerable research interest for their unique capacity to bridge nanotechnology and biology. Current studies predominantly concentrate on exploring nanozymes with diverse catalytic activities and their potential applications across various disciplines. Among them, nanoscale metal-organic frameworks (MOFs) are promising nanomaterials for constructing nanozymes. In this review, we firstly introduce the general construction strategies for MOF-based nanozymes. In addition, we also classify the MOF-based nanozymes in detail based on their catalytic performance. Thirdly, the recent research progress of MOF-based nanozymes in the field of biosensing, cancer therapy, antibacterial infection, and antioxidation are also comprehensively reviewed. Finally, we discuss the current challenges and future perspectives of MOF-based nanozymes, with the aim of assisting in their construction and maximizing their potential in bioapplications. It is hoped that we could provide scientists in materials science and biomedical research with valuable and comprehensive information, fostering advancements in interdisciplinary fields.

Ponytail Left Anterior Descending Artery: A Case Report.

Division of the anterior descending branch into many small arteries is a rare coronary anomaly. We report the case of a 64-year-old female with severe stenosis (>75%) in the proximal region of the anterior descending branch as indicated by coronary computed tomography angiography (CCTA). In addition, coronary angiography showed that the anterior descending branch of the coronary artery split into numerous small arteries, an anomaly that can confound clinical examination.

Exploring the effect of human-drone communication modality on safety and balance control in virtual construction environments.

This study examines the impact of Human-Drone Interaction (HDI) modalities on construction workers' safety and balance control within virtual environments. Utilising virtual reality (VR) simulations, the study explored how gesture and speech-based communications influence workers' physical postures and balance, contrasting these modalities with a non-interactive control group. One hundred participants were recruited, and their movements and balance control were tracked using motion sensors while they interacted with virtual drones through either gesture, speech, or without communication. Results showed that interactive modalities significantly improved balance control and reduced the risk of falls, suggesting that advanced HDI can enhance safety on construction sites. However, speech-based interaction increased cognitive workload, highlighting a trade-off between physical safety and mental strain. These findings underscore the potential of integrating intuitive communication methods into construction operations, although further research is needed to optimise these interactions for long-term use and in diverse noise environments.

This study examines the impact of Human-Drone Interaction (HDI) modalities on construction workers' safety and balance control within virtual environments with a human subject experiment. Results showed that interactive modalities significantly improved balance control and reduced the risk of falls.

Strategies for the Design and Construction of Nature-Inspired & Living Laboratory (NILL 1.0)TM Buildings.

This article explores the growing prominence of nature-inspired design philosophies in the context of sustainability and human well-being within the built environment and focuses on their application within laboratory buildings. Biomimicry and biophilic design are highlighted as key nature-inspired design approaches, with biomimicry drawing inspiration from nature for innovations and biophilic design promoting human health through enhancing the connection with the surrounding natural elements. This paper further discusses living building strategy as an emerging method for creating dynamic and adaptable spaces by prioritizing user experience through co-creation and focusing on sustainable and regenerative structures. The potential of integrating these approaches is emphasized using laboratory buildings as an example, with nature-inspired and living laboratories serving as models for future built environments that promote both environmental responsibility and a positive human experience. Accordingly, this work aims to investigate the design and construction of laboratory buildings based on nature-inspired design strategies and the living building concept. Moreover, the paper discusses the application of biomimicry and living building concepts within laboratory buildings as a novel contribution to the body of knowledge, and concludes by proposing the Nature-inspired & Living Laboratory (NILL 1.0)TM Building Assessment index to serve as a guideline for the design and construction of laboratory buildings using nature as an inspiration and the analogy of human body systems.

Nanomaterial-Mediated Immunosensors and Their Performance in Detecting Tumor Markers.

The detection of tumor markers is crucial for assessing the progression of specific cancers. Numerous research studies have shown that immunosensors can convert immune-specific response biosignals into visual signals, enabling the highly sensitive tracking and detection of tumor markers. This offers a promising solution for early cancer diagnosis. However, most tumor markers are inert molecules that are challenging to detect at low concentrations in the early stages of cancer. Therefore, there is a need to develop immunosensor analysis platforms with a higher sensitivity. Nanomaterials, with their advantages of high stability, low cost, and versatility in design, have emerged as ideal candidates for enhancing the performance of immunosensor analysis. In this paper, we review the design ideas of nanomaterials in antibody-based electrochemical, electrochemiluminescent, and photoelectrochemical immunosensors, including electrode interface modification, signaling probes for stimulating sensing signals, and design strategies of modified materials in signaling mechanisms. In addition, we have thoroughly analyzed the performance, advantages and disadvantages of different immunosensors. Therefore, the aim of this paper is to review the recent advances in advanced nanomaterial strategies for different immunosensors and their biomedical applications, and to point out the challenges and prospects of immunosensors in future clinical applications.

Assessing life cycle sustainability: A comprehensive review of concrete produced from construction waste fine fractions.

This paper presents an overview of the scholarly works employing the life cycle assessment (LCA) approach to evaluate the environmental impact of construction and demolition waste (CDW) fine fractions derived from concrete elements throughout their life cycle. Unlike conventional studies, this work addresses the challenge of reducing the carbon footprint associated with CDW-based building materials, emphasizing environmental impact mitigation. The study highlights that approximately 30% of CDW is landfilled, 50% is recycled, and 20% is used as fill material, underscoring the potential for increasing recycling rates through improved processing techniques and management practices. In the reviewed studies, most research has been conducted in Europe, Asia, the USA, and China. The primary and secondary data sources for the life cycle inventory (LCI) vary depending on the study region and locality. By exploring innovative practices and critical stages in CDW fine fractions utilization for concrete components, the study aims to contribute to greener construction practices and sustainable resource management. The distinctive aspect of this research lies in its comprehensive review of CDW-based aggregates, binders, and alternative cementitious materials, highlighting the significance of sustainable energy resources and transportation strategies in enhancing the sustainability of CDW-derived concrete. Key findings highlight the necessity of sustainable energy for pretreatment and optimized transportation strategies, including route planning and vehicle selection, to produce greener CDW fine fraction-based building materials. Additionally, the study suggests key steps and parameters required for defining the system boundary and preparing the inventory for conducting an LCA of building materials based on CDW fine fractions. Through a detailed analysis of environmental burdens at each production stage, this study seeks to promote the adoption of greener concrete solutions worldwide. The use of CDW in concrete production promotes environmental sustainability and greener concrete regardless of the region.

Suicides among construction workers in the United States, 2021.

BACKGROUND: Construction workers have the second highest suicide death rate; despite this, there is limited literature examining suicides in the industry, which is necessary to identify those at higher risk of death by suicide. The objective of this study was to examine the characteristics of those who died by suicide in construction to address this knowledge gap. METHODS: Data from the National Center for Health Statistics National Vital Statistics System 2021 public use Mortality Multiple Cause-of-Death file were used to identify deaths by suicide, while denominator data for rates come from the 2021 Current Population Survey. RESULTS: In 2021, construction workers were disproportionately affected by suicide deaths. Almost a fifth (17.9%) of deaths by suicide with a reported industry code were in construction, despite construction workers accounting for only 7.4% of the workforce. Male construction workers accounted for a majority (97.8%) of suicide deaths. The highest percent of deaths by suicide were among individuals who were white, non-Hispanic, completed high school or equivalent, and single, across construction and all industries for males and females. DISCUSSION AND CONCLUSIONS: Male and female construction workers had the highest rates of suicide across all characteristics when compared to all industries. Our findings support the need for ongoing prevention efforts within the industry. Future research is needed to understand suicide risk among certain characteristics and occupations. In addition, the work environment or other work-related factors should be studied to understand how the unique nature of the construction industry may be associated with higher suicide rates.

Multi-Sensor-Assisted Low-Cost Indoor Non-Visual Semantic Map Construction and Localization for Modern Vehicles.

With the transformation and development of the automotive industry, low-cost and seamless indoor and outdoor positioning has become a research hotspot for modern vehicles equipped with in-vehicle infotainment systems, Internet of Vehicles, or other intelligent systems (such as Telematics Box, Autopilot, etc.). This paper analyzes modern vehicles in different configurations and proposes a low-cost, versatile indoor non-visual semantic mapping and localization solution based on low-cost sensors. Firstly, the sliding window-based semantic landmark detection method is designed to identify non-visual semantic landmarks (e.g., entrance/exit, ramp entrance/exit, road node). Then, we construct an indoor non-visual semantic map that includes the vehicle trajectory waypoints, non-visual semantic landmarks, and Wi-Fi fingerprints of RSS features. Furthermore, to estimate the position of modern vehicles in the constructed semantic maps, we proposed a graph-optimized localization method based on landmark matching that exploits the correlation between non-visual semantic landmarks. Finally, field experiments are conducted in two shopping mall scenes with different underground parking layouts to verify the proposed non-visual semantic mapping and localization method. The results show that the proposed method achieves a high accuracy of 98.1% in non-visual semantic landmark detection and a low localization error of 1.31 m.

A review of truck driver persona construction for safety management.

The trucking industry urgently requires comprehensive methods to evaluate driver safety, given the high incidence of serious traffic accidents involving trucks. The concept of a "truck driver persona" emerges as a crucial tool in enhancing driver safety and enabling precise management of road transportation safety. Currently, the road transport sector is only beginning to adopt the user persona approach, and thus the development of such personas for road transport remains an exploratory endeavor. This paper delves into three key aspects: identifying safety risk characteristic parameters, exploring methods for constructing personas and designing safety management interventions. Initially, bibliometric methods are employed to analyze safety risk factors across five domains: truck drivers, vehicles, roads, the environment, and management. This analysis provides the variables necessary to develop personas for road transportation drivers. Existing methods for constructing user personas are then reviewed, with a particular focus on their application in the context of road transportation. Integrating contemporary ideas in persona creation, we propose a framework for developing safety risk personas specific to road transportation drivers. These personas are intended to inform and guide safety management interventions. Moreover, the four stages of driver post-evaluation are integrated into the persona development process, outlining tailored safety management interventions for each stage: pre-post, pre-transit, in-transit, and on-post. These interventions are designed to be orderly and finely tuned. Lastly, we offer optimization recommendations and suggest future research directions based on safety risk factors, persona construction, and safety management interventions. Overall, this paper presents a safety management-oriented research technology system for constructing safety risk personas for truck drivers. We argue that improving the design of the persona index system, driven by big data, and encompassing the entire driver duty cycle-from pre-post to on-post-will significantly enhance truck driver safety. This represents a vital direction for future development in the field.