Recurrencia en echinococcosis quística hepática

El tratamiento quirúrgico de la equinococosis quística hepática se asocia (entre otras), con una tasa de recurrencia actual de hasta 27%, aunque es infrecuente la recurrencia después de la exéresis total de un quiste intacto. Por lo general, la recurrencia ocurre producto del derrame de estructuras parasitarias vivas a alguna cavidad, o de dejar residuos de germinal, vesículas hijas o protoescólices durante la cirugía. La recurrencia suele ser asintomática, por lo que el diagnóstico depende, casi exclusivamente, de un seguimiento riguroso y prolongado en el tiempo, con controles clínicos, determinaciones serológicas, e imágenes. El tratamiento puede incluir el uso de albendazol, asociado a técnicas de radiología intervencionista o cirugía. El objetivo de este manuscrito fue generar un documento de lectura referente a la recurrencia de la equinococosis quística hepática.

Surgical treatment of hepatic cystic echinococcosis is associated (among others), with a current recurrence rate of up to 27%; although recurrence after total resection of an intact cyst is rare. In general, recurrence occurs as a result of the spillage of living parasitic structures into a cavity, or of leaving germinal residues, daughter vesicles, or protoscolices during surgery. Recurrence is usually asymptomatic, so the diagnosis depends almost exclusively on a rigorous and prolonged follow-up, with clinical controls, serological determinations, and images. Treatment may include the use of albendazole, followed by interventional radiology techniques or surgery. The aim of this manuscript was to generate a reading document regarding the recurrence of hepatic cystic echinococcosis.

Surgery for hepatic hidatidosis. Risk factors and variables associated with postoperative morbidity. Overview of the existing evidence. / Cirugía de la hidatidosis hepática. Factores de riesgo y variables asociadas al desarrollo de morbilidad postoperatoria. Revisión global de la evidencia existente.

There are few publications related to postoperative morbidity in hepatic hydatidosis and these have mixed results. The aim of this study was to determine risk and protective factors of postoperative morbidity in patients operated on for hepatic hydatidosis. A comprehensive review was made of the evidence, based on systematic reviews, clinical analyses and observational studies, obtained from the Trip Database, BVS, SciELO, Cochrane Central Register of Controlled Trials, WoS, MEDLINE, EMBASE, SCOPUS, EBSCOhost, IBECS, ePORTUGUESe, LILACS and WHOLIS. 1,087 related articles were identified; 69 fulfilled the selection criteria (2 systematic reviews, 3 clinical trials and 64 observational studies). Age, history of previous surgery for hepatic hydatidosis, location in the hepatic center, existence of biliary communications and evolutionary complications of the cyst were identified as risk factors, and radical surgical techniques as protective factors. Risk and protective factors were identified; however, the studies are few and the quality moderate to low.

Early and late outcomes of surgery of non-complicated liver hydatid / Resultados precoces y tardíos de la cirugía de la hidatidosis hepática no complicada

Hepatic echinococcosis (HE) is a prevalent health problem, and there is limited published information regarding HE surgery. On the other hand, postoperative morbidity (POM) has not varied significantly. The aim of this study was to describe early and late outcomes in terms of POM of a series of patients with non-complicated liver hydatid cysts (NLHC) treated surgically. Prospective cohort. We included patients undergoing surgery for NLHC in the Hospital Regional and Clínica in Temuco, between 2000 and 2015. The main outcome variable was the development of early and late POM. Other variables of interest were hospital stay, mortality and recurrence. Surgical techniques used were total or subtotal pericystectomy and liver resection. Percentages, measures of central tendency and dispersion, and incidence were calculated. We studied 136 patients with a median age of 41 years and 60.3 % female The median ultrasound diameter of the cysts was 15.0 cm. The median surgical time was 95 minutes. The incidence of POM was 9.6 %, 92.3 % of whose cases were Grade I or II Dindo & Clavien. The aetiology was 5.9 % and 3.7 % medical complications of surgical complications. There was no mortality and with a median follow up of 115 months, recurrence was observed in one patient, representing an incidence of 0.7 %. POM was determined in a cohort of patients with NLHC throughout an extended follow-up period, and the incidence and gravity of POM is smaller and of lower gravity than those previously published.

Siendo una equinococosis hepática (EH) un problema de salud prevalente, la información publicada respecto a la cirugía de EH no es abundante. Por otro lado, la morbilidad postoperatoria (MPO) no ha variado de forma muy significativa. El objetivo de este estudio fue describir los resultados tempranos y tardíos en términos de MPO de una serie de pacientes con quistes hidatídicos hepáticos no complicados (QHHN) tratados quirúrgicamente. Estudio de cohorte prospectiva. Se incluyeron pacientes sometidos a cirugía para QHHN en el Hospital Regional y Clínica en Temuco, entre 2000 y 2015. La variable resultado principal fue desarrollo de MPO temprana y tardía. Otras variables de interés fueron estancia hospitalaria, mortalidad y recurrencia. Las técnicas quirúrgicas utilizadas fueron periquistectomía total o subtotal y resección hepática. Se calcularon porcentajes, medidas de tendencia central y dispersión, e incidencia. Se estudiaron 136 pacientes con una mediana de edad de 41 años; 60,3 % de los cuales son mujeres. La mediana del diámetro de los quistes y del tiempo quirúrgico fue de 15,0 cm y 95 min. Respectivamente. La incidencia de MPO fue 9,6 %, de los cuales 92,3 % fueron Grado I o II de Dindo y Clavien. La etiología fue: 5,9 % de complicaciones médicas y 3,7 % de complicaciones quirúrgicas. No hubo mortalidad; y con una mediana de seguimiento de 115 meses, se determinó una incidencia de recidiva de 0,7 % (1 paciente, en el período estudiado). Se describe la MPO de una cohorte de pacientes con QHHN. La morbilidad observada es inferior a la publicada y de bajo nivel de gravedad.

Surgical management of pulmonary hydatid cysts: is size an important prognostic indicator?

Giant hydatid cysts of the lung (diameter, ≥10 cm) are considered more difficult to treat surgically than are smaller cysts. We reviewed our experience with giant pulmonary hydatid cysts, focusing on clinical symptoms, cystic location, extent of surgery, and postoperative complications, according to age, long-term results, and comparison with non-giant cysts. From January 1988 to January 2008, 537 patients underwent surgery for pulmonary hydatid cysts. We separated patients into 2 groups: patients who had cysts <10 cm (group A) and those who had giant cysts (group B). Group B comprised 75 patients (14%). Giant cysts were more common in younger patients (mean age, 30 vs 32 yr; P=0.014). The most frequent complaints were cough, chest pain, and dyspnea. Patients with giant cysts were more often symptomatic at presentation (96% vs 88%; P=0.04). In both groups, lower-lobe locations predominated. Parenchyma-saving operations were almost uniformly performed for each group; however, a higher percentage of patients in group B required anatomic resection (4% vs 1%; P=0.038). Fifty-seven patients (10%) also underwent resection of concomitant liver cysts. Cystic rupture occurred more frequently in group B than in group A (27% vs 15%; P=0.01). There were no deaths in either group, nor were there significant differences in morbidity between groups.In summary, giant hydatid cysts of the lung occurred more often in younger patients and were more often symptomatic at presentation. Regardless of size, the cysts could usually be surgically treated without lung resection, and size did not appear to influence short-term perioperative outcomes.