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Journal of Leukemia & Lymphoma
; (12): 120-123, 2014.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-475301
RESUMO
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of non-Hodgkin's lymphoma.An uncommon subset with myc and either bcl-2 or bcl-6 rearrangement,also known as ‘double-hit’ lymphomas,is considered very aggressive clinical course and poor prognosis despite high-intensity chemotherapy.Recently,these lymphomas have received increased attention.This review explores the existing literatures for the involved genes with their functions,clinical features,diagnosis and treatment.