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1.
BMC Public Health ; 24(1): 1812, 2024 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-38972984

RESUMO

BACKGROUND: Smoking rationalisation beliefs are a huge barrier to quitting smoking. What types of rationalisations should be emphasised in smoking cessation interventions? Although past literature has confirmed the negative relationship between those beliefs and motivation to stop smoking, little is known regarding the importance and performance of those beliefs on motivation with varying cigarette dependence. The study aimed to ascertain rationalisations that are highly important for motivation yet perform poorly in different cigarette dependence groups. METHODS: The cross-sectional study was conducted from November 19 to December 9, 2023 in Guiyang City, China. Adult male current smokers were enrolled. Partial least squares structural equation modelling was used to test the hypothesis. The multi-group analysis was used to determine the moderating effect of cigarette dependence, and the importance-performance map analysis was utilised to assess the importance and performance of rationalisations. RESULTS: A total of 616 adult male current smokers were analysed, and they were divided into the low cigarette dependence group (n = 297) and the high cigarette dependence group (n = 319). Except for risk generalisation beliefs, smoking functional beliefs (H1: -ß = 0.131, P < 0.01), social acceptability beliefs (H3: ß = -0.258, P < 0.001), safe smoking beliefs (H4: ß = -0.078, P < 0.05), self-exempting beliefs (H5: ß = -0.244, P < 0.001), and quitting is harmful beliefs (H6: ß = -0.148, P < 0.01) all had a significant positive influence on motivation. Cigarette dependence moderated the correlation between rationalisations and motivation. In the high-dependence group, the social acceptability beliefs and smoking functional beliefs were located in the "Concentrate Here" area. In the low-dependence group, the social acceptability beliefs were also situated in there. CONCLUSIONS: Social acceptability beliefs and smoking functional beliefs showed great potential and value for improvement among high-dependence smokers, while only social acceptability beliefs had great potential and value for improvement among low-dependence smokers. Addressing these beliefs will be helpful for smoking cessation. The multi-group analysis and the importance-performance map analysis technique have practical implications and can be expanded to other domains of health education and intervention practice.


Assuntos
Motivação , Abandono do Hábito de Fumar , Humanos , Masculino , China , Estudos Transversais , Adulto , Abandono do Hábito de Fumar/psicologia , Pessoa de Meia-Idade , Fumantes/psicologia , Fumantes/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Adulto Jovem , Tabagismo/psicologia , Tabagismo/terapia , População do Leste Asiático
2.
Qual Res ; 24(3): 628-646, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38855362

RESUMO

Side comments and conversations in focus groups can pose challenges for facilitators. Rather than seeing side comments as problematic behavior or "failed" data, we argue that they can add to and deepen analyses. Drawing on focus group data with grade nine students from a study on early work, in this methodological paper we discuss three patterns. First, side comments have highlighted where participants required clarification, and illustrated their views and questions about the research process. Second, side comments added new data to our analysis, including personal reflections, connections to others' comments, and information about participants' uncertainties about the research topics. Third, these comments offered insight into peer relations and dynamics, including participants' reflections on age, and how they deployed gender relations in their discussions. Provided that their use fits within established ethical protocols, we argue that there is a place for attention to side comments, especially in focus group research with young people where adult-teen hierarchies and peer dynamics might lead young people to engage more with peers than directly respond to researchers' questions.

3.
Accid Anal Prev ; 204: 107648, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38833986

RESUMO

Illegal lane-transgressing is a typical aberrant riding behavior of riders of two-wheelers, i.e., motorcycles, bicycles, and e-bikes, which is highly frequent in accident reports. However, there is insufficient attention to this behavior at present. This study aims to explore the socio-psychologic factors that influence the illegal lane-transgressing behavior of two-wheeler riders when overtaking. For this purpose, a questionnaire was first composed. The questionnaire included the behavioral intention of two-wheeler riders towards illegal overtaking behavior and five influencing factors: safety knowledge, descriptive norms, injunctive norms, perceived behavior control, and risk perception. Second, a survey was conducted on different two-wheeler riders in Xi'an. Third, various types of two-wheelers were analyzed jointly and separately by structural equation models and analyses of variance. Results show that e-bike riders were more similar to motorcycle riders in behavioral intentions, with their risk perception weaker than other riders. Descriptive norms and perceived behavior control played the most significant roles in the structural equation model. It was also found that two-wheeler riders with a car license had better traffic safety performance. Based on the above results, it is recommended that attention be paid to illegal lane-transgression in the process of law enforcement and education, and a higher level of safety training should be provided for two-wheeler riders.


Assuntos
Acidentes de Trânsito , Intenção , Motocicletas , Humanos , Motocicletas/legislação & jurisprudência , Masculino , Adulto , Feminino , Inquéritos e Questionários , Acidentes de Trânsito/prevenção & controle , Adulto Jovem , Ciclismo , Condução de Veículo/legislação & jurisprudência , Condução de Veículo/psicologia , Segurança , Normas Sociais , China , Pessoa de Meia-Idade , Adolescente , Assunção de Riscos
4.
Heliyon ; 10(11): e31783, 2024 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-38828315

RESUMO

During the COVID-19 pandemic, quarantines effectively prevented the spread of COVID-19 but also caused people to develop mental health problems. We thus aimed to verify the impact of social support and resilience on mental health and to uncover the moderating role played by time in isolation during the post-pandemic era. We administered a cross-sectional survey to 510 college students. The results found that social support directly and negatively predicted mental health problems, and this relationship was mediated by resilience. Through multigroup analysis, resilience partially mediated the relationship between social support and mental health during period of isolation 1 (PI1) and fully mediated this relationship during period of isolation 2 (PI2) and period of isolation 3 (PI3). Moreover, the path coefficient of resilience to mental health at T3 was significantly higher than that at T2. Thus, the effect of resilience on mental health increases with the duration of time in isolation.

5.
Psychol Sport Exerc ; 74: 102656, 2024 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-38723756

RESUMO

Until now, research on growth following sport injury has relied exclusively on retrospective reports and nomothetic measures drawn from other fields of research. Therefore, to more objectively explore growth following sport injury pre- and post-injury, rather than retrospectively, this study adapts and examines the psychometric properties of the Athlete Psychological Well-Being Inventory (APWBI), which can be used throughout the sport injury process (i.e., prior to and following sport injury). A sample of 164 athletes free from injury (71.3 % men; M age = 19.7 years, SD = 2.1) were compared to a sample of 168 athletes with history of previous injury (73.2 % men; M age = 19.7 years, SD = 2.1). Multigroup Confirmatory Factor Analysis demonstrated the measurement and factor equivalence between the APWBI and a retrospective measure, the Sport Injury-Related Growth Inventory (SIRGI). The APWBI also showed satisfactory to excellent internal consistency reliability for all its sub-dimensions ("sense of mastery", "positive relations with others", "responsibility for one's health", "self-awareness", "emotional ability", "purpose in life", "purpose in sport", and "body awareness") and for the total score. Analysis of the relationships with other self-report measures (i.e., the Positive Functioning Inventory, the Rosenberg's Self-Esteem Scale, and the Lie Scale) provided convergent and discriminant evidence to support the construct validity of the instrument. To conclude, the APWBI is a valid and reliable instrument for use within English-speaking athletes of various competitive levels (from local/county to international level).

6.
Medicina (Kaunas) ; 60(4)2024 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-38674320

RESUMO

Background and Objectives: Research into the relationship between occupation and dental fear and anxiety (DFA) is scarce. This exploratory study aimed to compare the level of DFA and its association with its predictors amongst adults from different occupational groups. Materials and Methods: A cross-sectional study with 422 respondents from four occupational groups (physicians, teachers, industry workers, and artists) was carried out. A questionnaire on previous dental experience using the Dental Anxiety Scale (DAS), Dental Fear Survey (DFS), and Self-Esteem Scale was self-administered electronically. The data analysis involved descriptive statistics and structural equation modeling (SEM). Results: The DFA levels differed significantly across the occupational groups, with the lowest mean scores among physicians (DAS = 9.29 (SE 0.39); DFS-1 = 14.67 (0.63); DFS-2 = 33.94 (1.69)) and the highest mean scores among artists (DAS = 10.74 (0.38); DFS-1 = 17.19 (0.71); DFS-2 = 41.34 (1.92)). A significant impact of self-esteem on DFA was observed among physicians, teachers, and artists, but not among industry workers. Multi-group analysis with SEM revealed differences in the variable association (Chi-squared = 53.75; df = 21; p < 0.001), thus rejecting the hypothesis of the same mechanism underlying DFA across occupational groups. Conclusions: Individuals from various occupations experience DFA at different levels, and there are different mechanisms underlying their DFA. These findings can provide valuable insights for dental practitioners in developing tailored approaches to reduce the feeling of DFA of their patients.


Assuntos
Ansiedade ao Tratamento Odontológico , Humanos , Ansiedade ao Tratamento Odontológico/psicologia , Feminino , Estudos Transversais , Masculino , Adulto , Inquéritos e Questionários , Pessoa de Meia-Idade , Ocupações/estatística & dados numéricos , Autoimagem
7.
Behav Sci (Basel) ; 14(4)2024 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-38667143

RESUMO

This paper studies the factors that influence tourists' risk perceptions of various destinations with different attributes and sociocultural profiles. Factor analysis is utilised to investigate the determinants of risk perceptions, finding that they are influenced both by the type of risk (delinquency, health, accident, environment and catastrophe) and by the characteristics of the destination regarding the management of risk. Structural equations modelling is conducted to study the relationships between risk perceptions, destination image and visiting intentions across destinations. Multi-group analysis across different destinations proves that tourists' risk perceptions have different influences on destination image and visiting intentions. The results show that there are significant differences according to the predominant religion at the destinations, i.e., Muslin and Christian. The implication is that different dimensions of perceived risks and destination socio-culture contexts have different influences on the behaviour of tourists.

8.
Front Psychol ; 15: 1343063, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38476395

RESUMO

Introduction: The interpersonal behavior questionnaire (IBQ) is an instrument that measures support and thwarting interpersonal behaviors based on the self-determination theory (SDT). The aim of this work was to adapt the IBQ to the Spanish spoken in Mexico and to examine its psychometric properties (structural validity, discriminant validity, composite reliability, factorial invariance, and nomological validity) in a sample of athletes. Methods: For this purpose, 472 athletes (average age 17.15 years; SD = 1.47) completed a question booklet. Results and discussion: Confirmatory factor analysis supported the structure of six related factors, three factors of behaviors that support autonomy, competence, and relatedness, and three factors of behaviors that thwarting them. The internal consistency of each factor was also supported, as well as the average variance extracted. However, the discriminant validity between the factors of competence and relatedness in their dimensions of support, on the one hand, and thwarting, on the other, is questioned. Factorial invariance was confirmed across gender (men and women) and sport type (individual and team). Nomological validity is in accordance with theory and empirical literature. More studies of the IBQ in sport are necessary to see if these results are a fortuitous product or if they manifest themselves consistently.

9.
BMC Geriatr ; 24(1): 142, 2024 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-38336656

RESUMO

OBJECTIVE: Social relationships have been extensively researched as having compelling health benefits. Nevertheless, these issues are understudied in low-income countries like India. This study investigates whether intergenerational solidarity or the social relationship developed in the household context and social participation or the social relationships developed in the community context are the critical determinants of subjective wellbeing (SWB) of older adults in India. In addition, this study also investigates whether gender moderates the association between social relationships and subjective wellbeing (SWB). METHODS: This study utilises a latent variable approach to investigate the association between social relationships and SWB among older adults (aged 60 or older, N = 9,852) based on a cross-sectional analysis of data from Building a Knowledge Base on Population Ageing in India (BKPAI) (2011). I tested the moderating effect of gender by employing a multigroup analysis in structural equation modelling that incorporated social relationships and other predictors of SWB. RESULTS: The study suggests that social participation has a significant protective impact on elderlies' SWB, and gender doesn't moderate the relation. Intergenerational solidarity has a significant health protective impact on older adults' SWB; there is a significant moderating impact of gender. Specifically, functional and consensual solidarity have significant moderating effects of gender. Affectional solidarity, although a significant predictor of older adults' SWB, and gender don't moderate the relation. CONCLUSION: The study suggests taking into account a variety of social relationships as well as gender roles when attempting to understand SWB at a later age. The results are discussed in terms of how gender roles impact social relationships and how men and women evaluate SWB differently based on those relationships.


Assuntos
Envelhecimento , Relações Interpessoais , Masculino , Humanos , Feminino , Idoso , Estudos Transversais , Participação Social , Índia/epidemiologia
10.
J Multidiscip Healthc ; 17: 219-228, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38250309

RESUMO

Purpose: Supporting family caregivers is a major challenge for the healthcare system. The first points of contact are physicians, nurses and social services, which are not easily accessible. For this reason, an information platform has been developed to provide information for family caregivers caring for people with dementia at home. The aim of this article is to provide an insight into the didactic design of this platform. Sample and Methods: A didactic concept was developed based on didactic target group analysis and interviews with caring relatives (n=6). Results: The didactic concept of the digital platform takes into account the characteristics of family caregivers as learners, such as time constraints and reciprocity. Therefore two different learning paths, a long and a short version, are offered. Reciprocity is supported by information which are related to individual characteristics of the caring relation. This is made possible by an adaptation of the didactic method "anchored instructions": Family caregivers experience a problematic caring situation. They use the platform and central concepts related to this situation are offered as anchors. In chatbot mediated learning, these concepts are identified and, ideally, relevant information is provided in a short version. These concepts are displayed as a learning map and must be proactively selected. Chatbot mediated learning has the advantage that matching concepts are offered as a pre-selection. Especially for inexperienced carers who are not familiar with the concepts, this learning path seems to be suitable. Conclusion: The combination of learning through the "Information for Relatives" website and CML seems to meet all needs. In order to promote learner motivation, the chatbot should not only offer the identified concept, but also those related to this concept, in order to link new knowledge in one's own knowledge network.

11.
J Sports Sci Med ; 22(4): 637-644, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38045748

RESUMO

High-level sports competitions involve facing highly challenging situations. Athletes must maintain strong team cohesion with peers, have specific mental abilities, and high-stress control to overcome adversity and report high sports performance. This research aimed to identify team cohesion profiles and examine whether participants differed significantly in their mental abilities and stress management. The sample consisted of 146 promising and talented athletes from the Sports Talent Development of the Provincial Council of Guipúzcoa (Spain) (Mage = 20.08; SD = 4.68), who completed the questionnaire on Psychological Characteristics Related to Sports Performance (CPRD). Cluster analyzes revealed three profiles; (a) profile with low team cohesion; (b) profile with average team cohesion; (c) profile with high team cohesion. Results showed significant differences in mental abilities (i.e., positive self-talk), and marginally significant differences in self-confidence, between the profiles. The best scores were reported in profile (b). In conclusion, the combination of low individualism, high social cohesion, and medium team spirit seems to be the most recommendable for promoting mental abilities and self-confidence in athletes' samples. As practical implications, the programs that train the mental abilities of athletes and control management should consider the importance of team cohesion to obtain improvements in the results of the competitions.


Assuntos
Atletas , Desempenho Atlético , Humanos , Atletas/psicologia , Espanha
12.
Vínculo ; 20(2): 149-155, 20230000.
Artigo em Português | LILACS | ID: biblio-1532552

RESUMO

Objetivo: Com esta reflexão a autora pretende contribuir para uma maior compreensão dos fenómenos grupais presentes no trabalho de articulação (inter)institucional dos vários profissionais que intervêm na área da saúde mental comunitária. Metodologia: Partindo da sua experiência a autora reflete sobre as múltiplas formas de resistência que podemos encontrar nos grupos de profissionais que intervêm na área da saúde mental comunitária, nomeadamente as resistências que diretamente se manifestam na articulação de âmbito interinstitucional entre profissionais relacionando, de entre outros, o conceito de anti-grupo, cunhado por Morris Nitsun, com os entraves ao funcionamento destes grupos (inter)institucionais. Resultados: São identificados os fenómenos agressivos e destrutivos que se podem constituir como resistências e proposta a sua origem nos mecanismos psíquicos como a transferência, clivagens, deslocamentos, projeções e identificações projetivas. Conclusões: O pensamento e compreensão grupanalítica do funcionamento dos grupos de trabalho é fundamental para que o potencial agressivo e destrutivo dos grupos não seja desvalorizado, ignorado ou estimulado, contribuindo para o seu sucesso.


Objective: With this reflection, the author intends to contribute to a greater understanding of the group phenomena present in the work of inter-institutional articulation in the field of community mental health. Metodology: Based on her experience, the author reflects on the multiple forms of resistance that we can find in groups of professionals who intervene in the area of community mental health, namely the resistance that directly manifests itself in the inter-institutional articulation between professionals relating, among others, the anti-group concept, coined by Morris Nitsun, with the obstacles to the functioning of these inter-institutional groups. Results: Aggressive and destructive phenomena that can constitute resistances are identified and their origin is proposed in internal mechanisms such as transference, cleavages, projections and projective identifications. Conclusions: A groupanalytic thinking and understanding of the functioning of inter-institutional work groups is essencial so that the aggressive and destructive potential of groups is not devalued, ignored or stimulated, contributing to their success.


Objetivo: Con esta reflexión, el autor pretende contribuir a una mayor comprensión de los fenómenos grupales presentes en el trabajo de articulación interinstitucional en el campo de la salud mental comunitaria. Metodología: A partir de su experiencia, la autora reflexiona sobre las múltiples formas de resistencia que podemos encontrar en los grupos de profesionales que intervienen en el área de la salud mental comunitaria, a saber, la resistencia que se manifiesta directamente en la articulación interinstitucional entre profesionales que se relacionan, entre otros, el concepto de antigrupo, acuñado por Morris Nitsun, con los obstáculos para el funcionamiento de estos grupos interinstitucionales. Resultados: Se identifican fenómenos agressivos y destructivos que pueden constituir resistência y se propone su origen en mecanismos psíquicos como la transferência, escisiones, desplazamientos, proyecciones y identificaciones proyectivas. Conclusiones: El pensamiento grupoanalítico y la comprensión del funcionamento de los grupos de trabajo es fundamental para que el potencial agressivo y destructivo de los grupos no sea devaluado, ignorado o estimulado, contribuyendo a su éxito.


Assuntos
Humanos , Equipe de Assistência ao Paciente , Fenômenos Psicológicos
13.
Appl Neuropsychol Adult ; : 1-11, 2023 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-37988689

RESUMO

OBJECTIVE: This study analyzes the psychometric properties of the two forms (self-report and informant) of the Behavior Rating Inventory of Executive Function-Adult version (BRIEF-A) in a sample of healthy Portuguese adults. METHOD: The participants were 608 adults, 304 of whom answered the self-report form (ages 18-59; 137 male and 167 female) and 304 who answered the informant form (ages 18-70; 110 male and 194 female). RESULTS: The internal consistency for the indexes and the Global Executive Composite was very good (≥.90), whereas for the scales they were either acceptable (between .70 and .80) or good (≥.80), except for the Inhibit scale in both forms. Confirmatory factor analysis was used to test seven competing factor models for each of the forms. The original two-factor model (Behavioral Regulation and Metacognition Indexes) showed a slightly better model fit than the three-factor model (Behavioral Regulation, Emotional Regulation, and Metacognition Indexes) in both forms. The multiple-group analysis of the two-correlated-factor model across forms was supported (configural, metric, and partial scalar invariance). CONCLUSIONS: Overall, the BRIEF-A showed adequate psychometric properties, suggesting that it is a useful instrument to assess everyday executive functioning in healthy Portuguese adults.

14.
BMC Bioinformatics ; 24(1): 380, 2023 Oct 09.
Artigo em Inglês | MEDLINE | ID: mdl-37807043

RESUMO

BACKGROUND: By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to a new frontier in microbial ecology, promising the ability to leverage the microbiome to make crucial advancements in the environmental and biomedical sciences. However, this is challenging, as genomic data are high-dimensional, sparse, and noisy. Much of this noise reflects the exact conditions under which sequencing took place, and is so significant that it limits consensus-based validation of study results. RESULTS: We propose an ensemble approach for cross-study exploratory analyses of microbial abundance data in which we first estimate the variance-covariance matrix of the underlying abundances from each dataset on the log scale assuming Poisson sampling, and subsequently model these covariances jointly so as to find a shared low-dimensional subspace of the feature space. CONCLUSIONS: By viewing the projection of the latent true abundances onto this common structure, the variation is pared down to that which is shared among all datasets, and is likely to reflect more generalizable biological signal than can be inferred from individual datasets. We investigate several ways of achieving this, demonstrate that they work well on simulated and real metagenomic data in terms of signal retention and interpretability, and recommend a particular implementation.


Assuntos
Metagenoma , Microbiota , Microbiota/genética , Metagenômica/métodos , Genômica , Biologia Computacional/métodos
15.
Psychol Res Behav Manag ; 16: 3541-3560, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37675188

RESUMO

Purpose: This research seeks to conceptualize foreign language listening anxiety (FLLA) and provide its measurement, and further explore the influences of FLLA on self-perceived listening performance. Methods: In Study 1, semi-structured interviews explored FLLA-arousal situations. Follow-up reliability and validity tests for the newly-developed scale were testified. In Study 2, structural equation modeling explored the relationship between FLLA and self-perceived performance, which was followed by the comparison of the effects of different types of FLLA on self-perceived performance between English and non-English major students. Results: The componential factors of FLLA included two factors, namely general listening anxiety and listening test anxiety, and general listening anxiety was represented by FLLA in classroom, daily usage, and media learning. The results also showed that listening test anxiety negatively affected self-perceived performance; general listening anxiety positively affected listening test anxiety but did not affect self-perceived performance, and listening test anxiety played a full mediation role. Moreover, findings revealed that non-English major students' general listening anxiety was higher than that of English major students. However, the multi-group analysis showed that these two groups did not differ in the effect of general listening anxiety on listening test anxiety, and in the effects of listening anxieties on self-perceived performance. For the two groups, the mechanism of anxiety-and-performance relationship was consistent. Conclusion: The results of this research have expanded the knowledge of listening anxiety by distinguishing general listening anxiety from listening test anxiety. Moreover, by testifying the mediator of listening test anxiety, this research deepened the understanding of the effects of different types of FLLA on self-perceived listening performance and the intensity differences of listening anxieties in English and non-English majors. Furthermore, the research has contributed to the literature on FLLA research based on Complex Dynamic Systems Theory, and has practical pedagogical implications for future studies.

16.
BMC Gastroenterol ; 23(1): 263, 2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37528334

RESUMO

BACKGROUND: The effectiveness of chemotherapy in older adult patients with biliary tract cancer (BTC) remains to be established, despite the fact that the majority of patients diagnosed with BTC tend to be aged ≥ 70 years. In this study, we used three databases to examine the effectiveness of chemotherapy in a large patient population aged ≥ 70 years with metastatic BTC. METHODS: Using a large Japanese database that combined three data sources (Osaka Cancer Registry, Japan's Diagnosis Procedure Combination, the hospital-based cancer registry database), we extracted the data from patients pathologically diagnosed with metastatic BTC, between January 1, 2013, and December 31, 2015, in 30 designated cancer care hospitals (DCCHs). A cohort of patients with comparable backgrounds was identified using propensity score matching. The log-rank test was used to examine how chemotherapy affected overall survival (OS). RESULTS: Among 2,622 registered patients with BTC in 30 DCCHs, 207 older adult patients aged > 70 years with metastatic BTC were selected. Chemotherapy significantly improved the prognosis of older adult patients, according to propensity score matching (chemotherapy, 6.4 months vs. best supportive care, 1.8 months, P value < 0.001). The number of patients receiving chemotherapy tends to decrease with age. Gemcitabine plus cisplatin (GC) and gemcitabine plus S-1 (oral fluoropyrimidine) (GS) combination therapy were frequently performed in the chemotherapy group for patients under 80 years of age (70-74 years, 61.7%; 75-79 years, 62.8%). In contrast, monotherapy including GEM and S-1 was more frequently performed in age groups over 80 years (80-84 years, 56.2%; 85-89 years, 77.7%; ≥90 years, 100%). In the chemotherapy group among older adult patients aged < 85 years, the median OS was significantly longer according to age-group analysis of the 5-year age range following propensity score matching. CONCLUSIONS: In older adult patients with metastatic BTC who received chemotherapy, prolonged survival was observed. Chemotherapy may be a viable option for patients with metastatic BTC who are aged < 85 years.


Assuntos
Neoplasias dos Ductos Biliares , Neoplasias do Sistema Biliar , Humanos , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , População do Leste Asiático , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Gencitabina , Desoxicitidina/uso terapêutico , Cisplatino/efeitos adversos , Neoplasias dos Ductos Biliares/tratamento farmacológico
17.
J Neurosci Methods ; 398: 109950, 2023 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-37598941

RESUMO

BACKGROUND: Consistent noise variance across data points (i.e. homoscedasticity) is required to ensure the validity of statistical analyses of MRI data conducted using linear regression methods. However, head motion leads to degradation of image quality, introducing noise heteroscedasticity into ordinary-least square analyses. NEW METHOD: The recently introduced QUIQI method restores noise homoscedasticity by means of weighted least square analyses in which the weights, specific for each dataset of an analysis, are computed from an index of motion-induced image quality degradation. QUIQI was first demonstrated in the context of brain maps of the MRI parameter R2 * , which were computed from a single set of images with variable echo time. Here, we extend this framework to quantitative maps of the MRI parameters R1, R2 * , and MTsat, computed from multiple sets of images. RESULTS: QUIQI restores homoscedasticity in analyses of quantitative MRI data computed from multiple scans. QUIQI allows for optimization of the noise model by using metrics quantifying heteroscedasticity and free energy. COMPARISON WITH EXISTING METHODS: QUIQI restores homoscedasticity more effectively than insertion of an image quality index in the analysis design and yields higher sensitivity than simply removing the datasets most corrupted by head motion from the analysis. CONCLUSION: QUIQI provides an optimal approach to group-wise analyses of a range of quantitative MRI parameter maps that is robust to inherent homoscedasticity.


Assuntos
Algoritmos , Imageamento por Ressonância Magnética , Reprodutibilidade dos Testes , Imageamento por Ressonância Magnética/métodos , Encéfalo/diagnóstico por imagem , Movimento (Física)
18.
Front Psychiatry ; 14: 1053759, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37333924

RESUMO

Background: It is well known that depression and delinquency in adolescents are highly correlated, but longitudinal studies on the causal relationship between them are not active in East Asia compared to in Western culture. In addition, even the results of research on causal models and sex differences are inconsistent. Objectives: This study examines the longitudinal reciprocal effects between depression and delinquent behavior in Korean adolescents based on sex differences. Methods: We conducted multiple-group analysis by using an autoregressive cross-lagged model (ACLM). Longitudinal data from 2,075 individuals (2011-2013) were used for analysis. The longitudinal data are from the Korean Children and Youth Panel Survey (KCYPS), and data were used beginning with students at 14 years old (in the second grade of middle school) and tracked them until they were 16 (in the first grade of high school). Results: Boys' delinquent behaviors at 15 years (the third grade of middle school) affected their depression at 16 years (the first grade of high school). In contrast, girls' depression at 15 years (the third grade of middle school) influenced their delinquent behaviors at 16 years (the first grade of high school). Discussion: The findings support the failure model (FM) among adolescent boys and the acting-out model (ACM) among girls. The results imply that strategies to effectively prevent and treat delinquency and depression in adolescents must consider sex effects.

19.
In Vivo ; 37(4): 1873-1879, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37369488

RESUMO

BACKGROUND/AIM: Smoking has been reported to be a risk factor for a variety of diseases. In Japan, the Brief Job Stress Questionnaire (BJSQ) has been administered by the Ministry of Health, Labour and Welfare since December 2015, but few reports have focused on its relationship with smoking. We investigated the current situation of smokers among staff of Kagoshima University who underwent a medical check-up. PATIENTS AND METHODS: Of 2,478 people who underwent a medical check-up in May and June 2021, we targeted 2,237 workers who reported whether they smoked. We examined results of the medical check-up and BJSQ and the background of smokers (n=139, 6.2%). We compared smokers and non-smokers (n=2,098) using propensity score matching (PSM) for sex, age, drinking habits, medication for dyslipidaemia, and overtime working hours at a 1:1 ratio. RESULTS: The results showed that white blood cell count (p=0.044), platelet count (p<0.001), glutamyl transferase (p=0.023), and triglyceride (p=0.027) were significantly higher among current smokers in comparison with current non-smokers. Smokers reported significantly more stress than non-smokers in terms of social support (p=0.027). CONCLUSION: As a result of PSM, several blood test items related to non-communicable diseases (lifestyle-related diseases) showed high values in current smokers, and these individuals reported significantly more stress than non-smokers. According to the emphasis on group analysis in the Total Health Promotion Plan revised in 2020, our findings can be helpful in enhancing smoking cessation programs in the workplace.


Assuntos
Fumantes , Fumar , Humanos , Estudos Transversais , Pontuação de Propensão , Fumar/epidemiologia , Inquéritos e Questionários
20.
Nutrients ; 15(10)2023 May 12.
Artigo em Inglês | MEDLINE | ID: mdl-37242174

RESUMO

Iron deficiency is still widespread as a major health problem even in countries with adequate food supply. It mainly affects women but also vegans, vegetarians, and athletes and can lead to various clinical pictures. Biofortification of vitamin C-rich vegetables with iron may be one new approach to face this nutritional challenge. However, so far, little is known about the consumer acceptance of iron-biofortified vegetables, particularly in developed countries. To address this issue, a quantitative survey of 1000 consumers in Germany was conducted. The results showed that depending on the type of vegetable, between 54% and 79% of the respondents were interested in iron-biofortified vegetables. Regression analysis showed a relationship between product acceptance, gender, and area of residence. In addition, relationships were found between consumer preferences for enjoyment, sustainability, and naturalness. Compared to functional food and dietary supplements, 77% of respondents would prefer fresh iron-rich vegetables to improve their iron intake. For a market launch, those iron-rich vegetables appear especially promising, which can additionally be advertised with claims for being rich in vitamin C and cultivated in an environmentally friendly way. Consumers were willing to pay EUR 0.10 to EUR 0.20 more for the iron-biofortified vegetables.


Assuntos
Ferro , Verduras , Humanos , Feminino , Ferro da Dieta , Disponibilidade Biológica , Biofortificação , Comportamento do Consumidor
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