RESUMO
Gastric cancer (GC) is a major digestive tract malignancy in China, which seriously threatens the health of Chinese population. A large number of researches have demons-trated that screening, early detection and early treatment are effective in reducing the incidence and mortality of GC. The development of the guideline for GC screening, early detection and early treatment in line with epidemic characteristics of GC in China will greatly promote the homogeneity and standardization, and improve the effect of GC screening. This guideline was commissioned by the Bureau of Disease Control and Prevention of the National Health Commission. The National Cancer Center of China initiated and convened a working group comprising multidisciplinary experts. Following the World Health Organization Handbook for Guideline Development, this guideline combined the most up-to-date evidence of GC screening, China's national conditions, and practical experience in cancer screening. This guideline provided evidence-based recommendations with respect to the screening population, technology and procedure management, aiming to improve the effect of GC screening and provide scientific evidence for the GC prevention and control in China.
Assuntos
Detecção Precoce de Câncer , Neoplasias Gástricas , Pequim , China/epidemiologia , Detecção Precoce de Câncer/métodos , Humanos , Programas de Rastreamento , Neoplasias Gástricas/diagnóstico , Neoplasias Gástricas/prevenção & controleRESUMO
Gastric cancer (GC) is a major digestive tract malignancy in China, which seriously threatens the health of Chinese population. A large number of researches have demons-trated that screening, early detection and early treatment are effective in reducing the incidence and mortality of GC. The development of the guideline for GC screening, early detection and early treatment in line with epidemic characteristics of GC in China will greatly promote the homogeneity and standardization, and improve the effect of GC screening. This guideline was commissioned by the Bureau of Disease Control and Prevention of the National Health Commission. The National Cancer Center of China initiated and convened a working group comprising multidisciplinary experts. Following the World Health Organization Handbook for Guideline Development, this guideline combined the most up-to-date evidence of GC screening, China′s national conditions, and practical experience in cancer screening. This guideline provided evidence-based recommendations with respect to the screening population, technology and procedure management, aiming to improve the effect of GC screening and provide scientific evidence for the GC prevention and control in China.
RESUMO
Gastric cancer (GC) is a major digestive tract malignancy in China, which seriously threatens the health of Chinese population. A large number of researches have demons-trated that screening, early detection and early treatment are effective in reducing the incidence and mortality of GC. The development of the guideline for GC screening, early detection and early treatment in line with epidemic characteristics of GC in China will greatly promote the homogeneity and standardization, and improve the effect of GC screening. This guideline was commissioned by the Bureau of Disease Control and Prevention of the National Health Commission. The National Cancer Center of China initiated and convened a working group comprising multidisciplinary experts. Following the World Health Organization Handbook for Guideline Development, this guideline combined the most up-to-date evidence of GC screening, China's national conditions, and practical experience in cancer screening. This guideline provided evidence-based recommendations with respect to the screening population, technology and procedure management, aiming to improve the effect of GC screening and provide scientific evidence for the GC prevention and control in China.
Assuntos
Humanos , Pequim , China/epidemiologia , Detecção Precoce de Câncer/métodos , Programas de Rastreamento , Neoplasias Gástricas/prevenção & controleRESUMO
BACKGROUND: Adjuvant chemotherapy (adCx) is an integral part of multimodal treatment in resected pancreatic ductal adenocarcinoma (PDAC) and is recommended by the German S3 guideline since 2007 in all patients. We aimed to investigate the impact of this guideline at our institution. METHODS: In 151 of 403 pancreatic resections performed histopathology revealed PDAC. Follow-up data were available from 143 patients (95%) representing our study group. The rate of recommended, initiated and fully completed adCx was analyzed for period 1 (09/2003-07/2007) and period 2 (08/2007-08/2014). RESULTS: Our study group comprised 49 patients in period 1 and 94 patients in period 2. AdCx was recommended, initiated and completed in 42/49 (86%), 34/49 (69%) and 22/49 (45%) patients in period 1 and in 93/94 (99%), 78/94 (83%) and 49/94 (52%) patients in period 2, respectively. Only the increase in recommendations for adCx was statistically significant (pâ¯=â¯0.0024). Overall, only 50% (71/143) of patients fully completed the Cx protocol. Completed adCx resulted in a significantly longer (pâ¯=â¯0.0225) overall survival compared to patients with incomplete or without adCx. Multiple logistic regression revealed adCx (pâ¯=â¯0.0046) as independent factor of survival. The hazard ratio for fully completed adCx was 0.406 and for incomplete adCx 0.567. CONCLUSION: Our results indicate a high acceptance of the S3-guidline recommendation for adCx in resected PDAC in a routine setting, which, however, is completed in only 50% of all patients. Fully completed adCx had the most powerful effect on improving overall survival.
RESUMO
The thickness of the abdominal subcutaneous tissues is discussed in the data obtained in 40 middle-aged female patients(the range of the age 31 to 60 years) examined on a modern computed tomographic system. The authors have shown that the superficial fascia, which separates the superficial and deep layers of subcutaneous fat, forms a continuous circumferential fascial plane. We have analyzed cross-sectional CT images at the umbilical level in a middle ged women. The authors have made several linear measurements of the thickness of the superficial and deep fat compartments at various reference points around the trunk in order to demonstrate the regional distribution of the deep fat compartment. Our data shows the mean, standard deviation(SD) concerning the thickness measurements of the superficial and deep fat compartments around the abdomen in the 40 women. From these observations, we concluded that the thickness of subcutaneous tissue of superficial layer is relatively constant and the thickness of subcutaneous tissue of deep layer is greatest at posterolateral region with decrements in thickness at anterior, lateral region respectively. And such pattern is same as the total subcutaneous tissue thickness, therefore, relatively safe parts for much amount of liposuction around the abdomen are paralumbar region and anterior abdomen. Such study result could offer the appropriate depths for cannula insertion, that is, 18.8mm at anterior, 16.9mm at lateral and 32.5mm at posterolateral region. Such knowledge could offer a guide to the necessary depth of cannula insertion when performing of the SAL (suction-assisted lipectomy). It is deemed desirable to place the tip in the middle of the deep compartment.