RESUMO
Association of insulin like growth factor (IGF)-I gene polymorphism with blood concentration of IGF-I, body composition, bone age and response to combined exercise program in teen-aged children. The purpose of this study was to determine whether there are the differences of blood concentration of IGF-I, body composition, bone age and response to combined exercise program according to IGF-I gene polymorphism in Korean teen-aged children. Subjects were recruited by 143 teen-aged children (male: 78, female: 65) from elementary school. Twelve weeks exercise program was consisted of resistance training and aerobic exercise. For the comparison of items and responses to combined exercise program according to IGF-I gene polymorphism, blood concentration of IGF-I, skinfold thickness, body circumferences, and growth markers were measured at baseline and after intervention. Body weight, %fat, BMI, skinfold thickness, circumferences, blood concentration of IGF-I, and bone age showed no significant differences following to IGF-I gene polymorphism. Although body composition and blood concentration of IGF-I showed a positive change after 12 week exercise training, 12 week exercise-mediated changes of body composition and blood concentration of IGF-I showed no significant differences following to IGF-I gene polymorphism. In conclusion, IGF-I gene polymorphism no contributed to the differences of body composition, blood concentration of IGF-I, and 12 week exercise-mediated these changes in teen-aged children.
