1.
Practical Oncology Journal
; (6): 250-253, 2018.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-697942
RESUMO
The JMJD family is an important group of histone demethylase. JMJD2B belongs to one of its family members,and is a JMJD containing a JmjC domain. It mainly regulates chromatin structure,transcription and cell appearance. Recent studies from domestic and foreign have demonstrated that JMJD2B protein is high expressed in human malignant tumors,such as liver cancer,gas-tric cancer,breast cancer,kidney cancer,and skin cancer. Moreover,it also shows that JMJD2B is involved in the occurrence,develop-ment,migration,infiltration,and proliferation of malignant tumors.