RESUMO
Background In recent years, advances in the treatment of malignant tumors have improved life expectancy and diversified treatment options. However, maintaining high activities of daily living in patients is essential for appropriately treating the primary disease, and interventions for patients with impaired motor function will lead to improved quality of life. Here, we compared the muscle mass of malignant tumor patients who are visiting bone metastasis outpatient clinics with that of healthy subjects. Methods We compared the muscle mass of 61 malignant tumor patients with an Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2 (mean 66.3 ± 12.0 years; 30 males and 31 females) attending our bone metastasis outpatient clinic since 2018 with that of 315 healthy subjects (mean 65.0 ± 17.7 years; 110 males and 205 females). Body mass index, skeletal muscle mass, and body fat percentage were assessed by bioimpedance analysis, and the skeletal muscle mass index (SMI) was calculated. Results To eliminate age bias in the malignant tumor patients and healthy subjects, 1:1 propensity score matching was performed separately for males and females. There was no significant difference in right upper limb, left upper limb, right lower limb, or left lower limb mass or SMI between the two groups, whereas trunk muscle mass and muscle mass were significantly higher in the healthy females compared with malignant tumor females. Conclusion There was no significant difference in the SMI measured by bioimpedance analysis between the two groups in either males or females, while muscle mass and trunk muscle mass were significantly lower in female malignant tumor patients than in healthy subjects. These results suggest that even malignant tumor patients whose performance status was maintained enough to allow outpatient visits still had impaired motor function.
RESUMO
At present, most of the malignancies still have poor treatment and even poor prognosis .In the case of disease informing , the families of many patients with malignant tumors are inclined to conceal the disease based on the risks that may result in the patient ' s pain while patients want to know their disease diagnosis and prognosis . Telling patients the truth is helpful to promote the patients to participate in the treatment decision , cooperate with the treatment, prolong the survival time , improve the quality of life and also is the requirement of relevant laws and regulations, but it also faces many ethical conflicts in practice .Aiming at this, this paper proposed to strengthen health education , make necessary training to medical staff , design individual informative programs , cooperate rea-sonably with family members , and so on .
RESUMO
At present, most of the malignancies still have poor treatment and even poor prognosis .In the case of disease informing , the families of many patients with malignant tumors are inclined to conceal the disease based on the risks that may result in the patient ' s pain while patients want to know their disease diagnosis and prognosis . Telling patients the truth is helpful to promote the patients to participate in the treatment decision , cooperate with the treatment, prolong the survival time , improve the quality of life and also is the requirement of relevant laws and regulations, but it also faces many ethical conflicts in practice .Aiming at this, this paper proposed to strengthen health education , make necessary training to medical staff , design individual informative programs , cooperate rea-sonably with family members , and so on .
