Tinnitus-on the interplay between emotion and cognition.

Subjective tinnitus (hereafter tinnitus) is often considered and studied as a perceptual phenomenon. Accordingly, various abnormalities in the area of cognitive processing have been reported in patients with tinnitus. At the same time, the disorder is characterized by considerable emotional distress, which is associated with a high comorbidity of affective disorders. Here, we aim to outline the close link between cognition and emotion, and how current research from the field of cognitive neuroscience examines the processing and acquisition of emotional stimuli. The emotional valence of stimuli can be acquired after brief exposure to learning, leading from neutral to appetitive or aversive evaluation. In contrast to neutral stimuli, emotional stimuli attract attention very early (about 100 ms) during processing, leading to deeper processing and corresponding memory effects. The involved subcortical and cortical network encompasses limbic and sensory areas. In particular, prefrontal regions are involved in the acquisition and evaluation of emotional stimuli as also shown in studies of patients with affect disorders. The interplay of cognitive and emotional processes seems to be central to the development, maintenance, and treatment of tinnitus.

The influence of physical education at school on the attention of students aged 15-16 years / El impacto de la educación física en la escuela en la atención de los estudiantes de 15 a 16 años / O impacto da educação física na escola na atenção de estudantes de 15 a 16 anos

ABSTRACT Objectives: the influence of physical activity in physical education lessons on the attention indicators of schoolchildren. Material and Methods: 141 students, aged 15-16, who studied in the 9th grade, took part in the experiment. The main research method was the "Trondyke Test", which determines the level of attention development of students. The test was used before and after the physical education lesson 1 time per month for 5 months. Results: students who did not engage in physical education in the lesson were not able to significantly improve their performance in the test, which indicates a possible adaptation to the test after its first performance before the lesson. Students who were engaged in physical exercises could significantly increase the test results. Conclusion: the results obtained determine the effectiveness of the influence of a physical education lesson at school on the indicators of students attention. This study will serve as an additional motivation for students to engage in physical culture, since the impact of physical exercises has a positive effect not only on the development of physical qualities, but also on the attention of schoolchildren. Level of Evidence III; Retrospective Comparative Study.

RESUMEN Objetivos: la influencia de la actividad física en las clases de educación física en los indicadores de atención de los escolares. Material y métodos: Participaron en el experimento 141 escolares, de 15-16 años, que cursaban el noveno grado. El principal método de investigación fue la "Prueba de Trondyke", que determina el nivel de desarrollo de la atención de los escolares. La prueba se usó antes y después de la lección de educación física una vez al mes durante 5 meses. Resultados: los jóvenes que no participaron en educación física en la lección no pudieron mejorar significativamente su rendimiento en la prueba, lo que indica una posible adaptación a la prueba después de su primera actuación antes de la lección. Los escolares que realizaban ejercicios físicos pudieron aumentar significativamente los resultados de la prueba. Conclusión: los resultados obtenidos determinan la efectividad de la influencia de una lección de educación física en la escuela sobre los indicadores de atención de los escolares. Este estudio servirá como una motivación adicional para que los estudiantes participen en la cultura física, ya que el impacto de los ejercicios físicos tiene un efecto positivo no solo en el desarrollo de las cualidades físicas, sino también en la atención de los escolares. Nivel de Evidencia III; Estudio Comparativo Retrospectivo.

RESUMO Objetivos: a influência da atividade física nas aulas de Educação Física nos indicadores de atenção dos escolares. Material e métodos: participaram do experimento 141 escolares, de 15 a 16 anos, que estudaram na 9a série. O principal método de pesquisa foi o "teste de Trondyke", que determina o nível de desenvolvimento da atenção dos escolares. O teste foi utilizado antes e depois da aula de Educação Física uma vez por mês durante 5 meses. Resultados: Os estudantes que não praticaram Educação Física na aula não conseguiram melhorar significativamente seu desempenho no teste, o que indica uma possível adaptação ao teste após sua primeira apresentação antes da aula. Os estudantes que estavam envolvidas em exercícios físicos foram capazes de aumentar significativamente os resultados do teste. Conclusão: os resultados obtidos determinam a eficácia da influência de uma aula de Educação Física na escola nos indicadores de atenção das crianças. Este estudo servirá como uma motivação adicional para os estudantes se envolverem na cultura física, uma vez que o impacto dos exercícios físicos tem um efeito positivo não apenas no desenvolvimento das qualidades físicas, mas também na atenção dos alunos. Nível de Evidência III; Estudo Comparativo Retrospectivo.

Attention, response inhibition, and hoarding: A neuropsychological examination.

Background and aims: The prominent cognitive-behavioral model of hoarding posits that information processing deficits contribute to hoarding disorder. Although individuals with hoarding symptoms consistently self-report attentional and impulsivity difficulties, neuropsychological tests have inconsistently identified impairments. These mixed findings may be the result of using different neuropsychological tests, tests with poor psychometric properties, and/or testing individuals in a context that drastically differs from their own homes. Methods: One hundred twenty-three participants (hoarding = 63; control = 60) completed neuropsychological tests of sustained attention, focused attention, and response inhibition in cluttered and tidy environments in a counterbalanced order. Results: Hoarding participants demonstrated poorer sustained attention and response inhibition than the control group (CPT-3 Omission and VST scores) and poorer response inhibition in the cluttered environment than when in the tidy environment (VST scores). CPT-3 Detectability and Commission scores also indicated that hoarding participants had greater difficulty sustaining attention and inhibiting responses than the control group; however, these effect sizes were just below the lowest practically meaningful magnitude. Posthoc exploratory analyses demonstrated that fewer than one-third of hoarding participants demonstrated sustained attention and response inhibition difficulties and that these participants reported greater hoarding severity and greater distress in the cluttered room. Discussion and conclusions: Given these findings and other studies showing that attentional difficulties may be a transdiagnostic factor for psychopathology, future studies will want to explore whether greater sustained attention and response inhibition difficulties in real life contexts contribute to comorbidity and functional impairment in hoarding disorder.

[Tinnitus-on the interplay between emotion and cognition. German version]. / Tinnitus im Wechselspiel zwischen Emotion und Kognition.

Subjective tinnitus (hereafter tinnitus) is often considered and studied as a perceptual phenomenon. Accordingly, various abnormalities in the area of cognitive processing have been reported in patients with tinnitus. At the same time, the disorder is characterized by considerable emotional distress, which is associated with a high comorbidity of affective disorders. Here, we aim to outline the close link between cognition and emotion, and how current research from the field of cognitive neuroscience examines the processing and acquisition of emotional stimuli. The emotional valence of stimuli can be acquired after brief exposure to learning, leading from neutral to appetitive or aversive evaluation. In contrast to neutral stimuli, emotional stimuli attract attention very early (about 100 ms) during processing, leading to deeper processing and corresponding memory effects. The involved subcortical and cortical network encompasses limbic and sensory areas. In particular, prefrontal regions are involved in the acquisition and evaluation of emotional stimuli as also shown in studies of patients with affect disorders. The interplay of cognitive and emotional processes seems to be central to the development, maintenance, and treatment of tinnitus.

A protocol for a scoping review of the use of mental simulation and full-scale simulation in practising healthcare decision-making skills of undergraduate nursing students.

AIM: This scoping review aims to explore the effect of FSS and mental simulation on the decision-making skills of nursing students. BACKGROUND: Full-scale simulation (FSS) has been the most used simulation modality in nursing education due to its applicability to enhance both technical and non-technical skills. However, FSS can be excessively costly and other factors such as technophobia and lack of trained staff and support make FSS less accessible, especially for nursing education. Therefore, a novel mental simulation that is interactive and supported by visual elements can be a substitute for FSS, at least for some of the skills, such as clinical decision-making. Reviews comparing the effectiveness of FSS and mental simulation on decision-making skills in nursing students are lacking. Further knowledge on the effectiveness of these two modalities on decision-making skills for nursing students is needed to inform the nursing education curriculum and to decide between the two modalities. DESIGN: This protocol adheres to the guidelines outlined in the PRISMA extension for scoping reviews (PRISMA-scr) checklist. METHOD: The methodological framework for scoping reviews will be followed for this scoping review. Scopus, EBSCOhost the Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE and for the grey literature ERIC and BASE will be searched for related studies. The search will be limited to January 2008 and April 2023 (up-to-date) and English. A detailed search strategy was developed with an experienced research information manager and this strategy will be adapted to each database. A single screening will be performed by an author who will screen all abstracts and titles and full-text publications. After the study selection step of the framework, the data from the included studies will be charted using a data extraction form. The data will be synthesised by comparing the effect of FSS and mental simulation on decision-making skills. CONCLUSION: A synopsis of the publication on FSS and mental simulation on nurse students' decision-making skills will be useful for stakeholders when choosing between two modalities to deliver decision-making skills to nursing students and also help to inform the nursing education and simulation practice. SCOPING REVIEW REGISTRATION: Protocols.io (doi: 10.17504/protocols.io.e6nvw57y7vmk/v1).

Deciphering Functional Connectivity Differences Between Motor Imagery and Execution of Target-Oriented Grasping.

This study aimed to delineate overlapping and distinctive functional connectivity in visual motor imagery, kinesthetic motor imagery, and motor execution of target-oriented grasping action of the right hand. Functional magnetic resonance imaging data were obtained from 18 right-handed healthy individuals during each condition. Seed-based connectivity and multi-voxel pattern analyses were employed after selecting seed regions with the left primary motor cortex and supplementary motor area. There was equivalent seed-based connectivity during the three conditions in the bilateral frontoparietal and temporal areas. When the seed region was the left primary motor cortex, increased connectivity was observed in the left cuneus and superior frontal area during visual and kinesthetic motor imageries, respectively, compared with that during motor execution. Multi-voxel pattern analyses revealed that each condition was differentiated by spatially distributed connectivity patterns of the left primary motor cortex within the right cerebellum VI, cerebellum crus II, and left lingual area. When the seed region was the left supplementary motor area, the connectivity patterns within the right putamen, thalamus, cerebellar areas IV-V, and left superior parietal lobule were significantly classified above chance level across the three conditions. The present findings improve our understanding of the spatial representation of functional connectivity and its specific patterns among motor imagery and motor execution. The strength and fine-grained connectivity patterns of the brain areas can discriminate between motor imagery and motor execution.

Effects of Physical Exercise on Executive Function in Adults with Depression: A Systematic Review and Meta-Analysis.

Executive function is among the most affected cognitive dimensions in depression. Physical exercise may improve executive function (e.g., working memory, inhibition, cognitive flexibility), although this is without consensus on adults with depression. Through this systematic review, we aim to elucidate the effects of physical exercise programs on executive functions in adults with depression. The literature search was performed in four relevant electronic databases, combining keywords and medical subject headings, from inception until September 2022. Controlled interventions, involving adults with depression, and reporting working memory, inhibition, and/or cognitive flexibility pre-post-intervention data, were considered includable. Results from meta-analyses included effect size (ES, i.e., Hedges' g) values reported with 95% confidence intervals (95%CIs), with p set at ≤0.05. Seven studies were included, including 202 men and 457 women (age: 21.0-51.2 years; mild-moderate depression). For working memory, a small favoring effect was observed in the experimental groups compared with controls (ES = 0.33, 95%CI = 0.04-0.61; p = 0.026; I2 = 64.9%). For inhibition, physical exercise had a small favoring non-significant effect compared with controls (ES = 0.28, 95%CI = -0.17-0.74; p = 0.222; I2 = 72.4%). Compared with the control group, physical exercise had a trivial effect on cognitive flexibility (ES = 0.09, 95%CI = -0.21-0.39; p = 0.554; I2 = 68.4%). In conclusion, physical exercise interventions may improve working memory behavioral measures in adults with mild-to-moderate depression when compared with active and passive control conditions. However, the reduced number of available high-quality studies precludes more lucid conclusions.

The Kids Are Alright (?). Infants' Development and COVID-19 Pandemic: A Cross-Sectional Study.

Objectives: The study aimed to assess and compare the global development in six-month-old infants before and during the pandemic restrictive social distancing measures. Methods: This cross-sectional nested study involved infants assessed through the Griffiths Scales of Child Development (GSCD) between September 2019 and April 2021. Infants were classified in a pre-COVID or a COVID group, considering the evaluation date and the restrictive measures in place. GSCD subscales and General Development Scores (GDS) were calculated and compared. Results: One hundred and four healthy term-born infants were evaluated. GDS in the COVID group (n:70; median: 94; IQR: 90-100) appeared significantly lower than in the pre-COVID group (n:34; median: 98; IQR: 97-103; p < 0.001). Language and personal-social-emotional subareas scores appeared the most affected. A decreasing trend of GDS along with the severity of restriction was observed. Conclusion: A reduction in infant development scores was observed during pandemic social distancing. Further studies are needed to systematize these findings and to address effective public health policies for infants and families during long-term forced isolation periods.

Positive Mental Health Literacy: A Concept Analysis.

Background: The positive component of Mental Health Literacy (PMeHL) refers to a person's awareness of how to achieve and maintain good mental health. Although explored recently, the term still lacks a clear definition among healthcare practitioners. Aim: To identify the attributes and characteristics of PMeHL, as well as its theoretical and practical applications. Methods: Literature search (using the Medline and CINAHL databases) and review, covering the last 21 years, followed by concept analysis according to the steps described by Walker and Avant approach. Results: Positive component of Mental Health Literacy is considered one component of MHL, integrating positive mental health. The concept's attributes include: (a) competence in problem-solving and self-actualization; (b) personal satisfaction; (c) autonomy; (d) relatedness and interpersonal relationship skills; (e) self-control; and (f) prosocial attitude. Four case scenarios (model, borderline, related and contrary cases) were used to clarify the antecedents (individual factors and social/contextual factors) and consequences (individual sphere; relational/social sphere; contextual/organizational sphere) of PMeHL. Conclusion: Positive component of Mental Health Literacy is considered a component of MHL, which deserves attention throughout the lifespan, in different contexts and intervention levels. Considering PMeHL as a multi-faceted and dynamic construct will help understand the mechanisms that improve mental health and promote healthy behaviors. Priority should be given to robust primary research focused on nursing interventions that enhance and sustain PMeHL in people and families.

Neurocognitive functioning and impulsivity in first-episode psychosis with suicidal ideation and behavior: A systematic review.

BACKGROUND: The prevalence of suicidal ideation (SI) and behavior (SB) among people suffering from psychotic disorders is a public health issue. Most suicide attempts (SAs) occur before or during the early phases of first-episode psychosis (FEP). Improving knowledge about the suicide risk in the early stages is essential to develop therapeutic and prevention strategies. We conducted a systematic review to investigate an association between neurocognitive impairments or a history of impulsive behavior and SI or SB among patients with FEP. METHOD: PRISMA guidelines were followed. Ten databases were searched using MeSH terms or key-words related to FEP, impulsivity or cognitive functioning measures and SI or SB, without restrictions for study design or length of follow-up. Included studies evaluated at least one cognitive function with neuropsychological tests or validated questionnaires, or provided records of impulsive behavior. RESULTS: Twenty one research papers were included from databases, bibliographic references or expert opinions. Among patients with FEP, seven studies showed more pronounced neuropsychological impairments, especially regarding attention, processing speed, executive functioning and theory of mind in patients that had attempted suicide. No association was found between cognitive impairments on neuropsychological tests and SI. Previous non-suicidal impulsive behaviors were associated with SAs and suicide. CONCLUSION: Our review suggests an association between neurocognitive impairments and SAs among patients with FEP. Records of impulsive behavior are also associated with SB in that population. Further research on the neuropsychology of FEP is necessary to identify how these impairments facilitate SB and evaluate their potential utility as therapeutic targets.

Contemporaneous Emotion Regulation Theoretical Models: A Systematic Review / Modelos Teóricos Contemporáneos de Regulación Emocional: Una Revisión Sistemática

ABSTRACT Background: Emotions and their regulation are a phenomenon present in everyday life. Despite its relevance and growing interest, a consensual and univocal definition has not yet been reached. Objective: This paper aims to review contemporary theoretical models of emotion regulation, looking for agreements and divergences between authors. It seeks to identify the main processes considered when working with emotional dysregulation. Method: Our team conducted a systematic review in the form of a narrative synthesis following the guidelines of the PRISMA statement. The database used were SCOPUS, PUBMED, and Dialnet. We included articles published between 2018 and 2020, which have been peer-reviewed in indexed scientific journals, whose central theme was the theoretical presentation of the construct of emotional regulation. We excluded articles that conceptualized only one dimension of the construct focused on specific populations and empirical studies without a theoretical conceptualization of the construct. The information was systematized in a table identifying authors' information, country of institutional affiliation, main characteristics of the given definition of emotion regulation, regulation skills mentioned, and underlying theoretical frameworks. Results: We identified ten different theoretical frameworks that propose models of emotion regulation. The main components found in the definition were the complexity of the construct, goal orientation, intra- or interpersonal regulation, the proposal of moderators, and its voluntary character. Discussion: There is a consensus on the use of emotion regulation strategies to adapt to environmental demands, achieve goals and increase well-being. We identify that people's learning history is an important factor in the development of emotional regulation skills. In addition, context and personality traits are proposed as moderators of the therapeutic efficacy of interventions focused on emotional regulation. Further studies along these lines would favor the implementation of preventive interventions and the personalization of treatments.

RESUMEN Antecedentes: Las emociones y su regulación son un fenómeno presente en la vida cotidiana. A pesar de su relevancia y creciente interés, aún no se ha alcanzado una definición consensuada y unívoca. Objetivo: El presente trabajo pretende revisar los modelos teóricos de regulación emocional contemporáneos buscando acuerdos y divergencias entre autores. Se busca identificar los principales procesos tomados en cuenta para el trabajo con la desregulación emocional. Método: Nuestro equipo realizó una revisión sistemática en forma de síntesis narrativa siguiendo las directrices de PRISMA. Las bases de datos utilizadas fueron SCOPUS, PUBMED y Dialnet. Se incluyeron artículos publicados entre 2018 y 2020, que han sido revisados por pares en revistas científicas indexadas, cuyo tema central fuera la presentación teórica del constructo de regulación emocional. Se excluyeron artículos que conceptualizaban una sola dimensión del constructo, se enfocaban en poblaciones específicas y estudios empíricos sin una conceptualización teórica del constructo. La información fue sistematizada en una tabla identificando información de los autores, país de afiliación institucional, características principales de la definición dada de regulación emocional, habilidades de regulación mencionadas y marco teórico de base. Resultados: Se identificaron diez marcos teóricos diferentes que proponen modelos de regulación de las emociones. Los principales componentes encontrados en las definiciones fueron la complejidad del constructo, la orientación a metas, la regulación intra o interpersonal, la propuesta de moderadores y su carácter voluntario. Discusión: Existe un consenso sobre el uso de estrategias de regulación de las emociones para adaptarse a las demandas del entorno, alcanzar metas y aumentar el bienestar. Identificamos que la historia de aprendizaje de las personas es un factor importante en el desarrollo de las habilidades de regulación emocional. Además, el contexto y los rasgos de personalidad son propuestos como moderadores de la eficacia terapéutica de las intervenciones centradas en la regulación emocional. Más estudios en esta línea favorecerían la implementación de intervenciones preventivas y la personalización de los tratamientos.

Accelerated Long-Term Forgetting: Prolonged Delayed Recognition as Sensitive Measurement for Different Profiles of Long-Term Memory and Metacognitive Confidence in Stroke Patients.

OBJECTIVE: Deficits in episodic memory are frequently reported after ischemic stroke. In standard clinical care, episodic memory is assessed after a 20-30 min delay, with abnormal memory decay over this period being characterized as rapid forgetting (RF). Previous studies have shown abnormal forgetting over a prolonged interval (days to weeks) despite normal acquisition, referred to as accelerated long-term forgetting (ALF). METHOD: We examined whether ALF is present in stroke patients (N = 91) using immediate testing (T1), testing after a short delay (20-30 min, T2), and testing after a prolonged delay (one week, T3). Based on performance compared to matched controls (N = 85), patients were divided into (1) patients without forgetting, (2) patients with RF between T1 and T2, and (3) patients with ALF at T3. Furthermore, confidence ratings were assessed. RESULTS: ALF was present in a moderate amount of stroke patients (17%), but ALF was even more prevalent in our stroke sample than RF after a 20-30 min delay (which was found in only 13% of our patients). Patients reported a lower confidence for their responses, independent of their actual performance. CONCLUSIONS: Adding a one-week delayed measurement may potentially assist in identifying patients with memory decrements that may otherwise go undetected.

Factors Associated With the Intention to Begin Physical Activity Among Inactive Middle-Aged and Older Adults.

Factors that affect physical activity (PA) behavior change are well established. Behavioral intention is a strong psychological predictor of behavior; however, there is less research on the factors that affect the intention to increase PA participation specifically, especially among adults in mid and later life who are inactive. Using data from the Canadian Community Health Survey, which was informed by the transtheoretical model (TTM), this study investigated the relationships between a range of demographic and biopsychosocial factors with the intention to become physically active among 1,159 inactive adults aged 40 years and older. Comparisons were made between participants reporting the intention to begin PA in the next 30 days (TTM Preparation; n = 610), 6 months (TTM Contemplation; n = 216), or not at all (TTM Precontemplation; n = 333). First, multinomial logistic regression identified age, sex, ethnicity, education, restriction of activities, self-perceived health, and community belonging as factors significantly associated with 30-day PA intention, while age and ethnicity were significantly associated with 6-month PA intention, compared with those reporting no intention. Second, binary logistic regression revealed that education was the only factor that differentially associated with intention timeframe as participants with lower levels of education were less likely to report PA intention in 30 days compared with 6 months. Findings demonstrate key demographic, biopsychosocial, and temporal factors that warrant consideration for tailored PA promotion programs that aim to effectively address the constraints and barriers that negatively influence PA intention among middle-aged and older adults.

Quais fatores cognitivos e linguísticos influenciam o processamento fonológico em adolescentes? / Which cognitive and linguistc factors influence phonological processing in adolescents?

RESUMO Objetivo Caracterizar o processamento fonológico em adolescentes e identificar habilidades linguísticas e funções cognitivas que o influenciam nessa faixa etária. Método Participaram 83 adolescentes típicos de 11 a 16 anos. Utilizaram-se os testes de consciência fonológica, nomeação automática rápida, avaliação neuropsicológica e leitura. Foi realizada a análise descritiva e a regressão linear com nível de significância de 5%. Resultados Em relação ao processamento fonológico, observou-se menor desempenho na tarefa de segmentação fonêmica, maior tempo de nomeação de objetos e desempenho dentro do esperado para a idade em memória operacional. Verificou-se associação recíproca entre nomeação rápida de objetos, de letras e memória operacional, entre nomeação rápida de letras e consciência fonológica. As funções executivas e a atenção influenciaram a memória operacional e a consciência fonológica. A memória verbal episódica semântica influenciou a memória operacional e, a leitura, a consciência fonológica. Conclusão O desempenho no processamento fonológico foi influenciado por habilidades linguísticas e cognitivas e sugere ainda estar em aprimoramento na adolescência.

ABSTRACT Purpose To characterize phonological processing of adolescents and to identify language skills and cognitive functions that influence their age group. Methods 83 typical adolescents aged from 11 to 16 years of age participated in the research. Phonological awareness tests, rapid automatic naming, neuropsychological assessment and reading were used. Descriptive analysis and linear regression were carried out with a 5% significance level. Results Regarding phonological processing, a lower performance was found in the phonemic segmentation task, longer times for object naming and performance as were expected for working memory of the age range. There was a reciprocal association between rapid naming of objects, letters and working memory, between rapid naming of letters and phonological awareness. Executive functions and attention influence working memory and phonological awareness. Semantic episodic verbal memory influenced working memory and reading, phonological awareness. Conclusion The performance in phonological processing was influenced by linguistic and cognitive skills which suggests they are still improving in adolescents.

Dignity status of lymphoma patients during perichemotherapy and its influencing factors / 白血病·淋巴瘤

Objective:To investigate the dignity status of lymphoma patients during perichemotherapy, and to analyze the influencing factors.Methods:The convenience sampling method was used to investigate 230 lymphoma patients during perichemotherapy in Affiliated Tumor Hospital of Xinjiang Medical University from August 2020 to February 2021 by using general data questionnaire and patient dignity scale. Dual logistic regression was used to analyze the influencing factors of dignity.Results:The dignity score of patients with malignant lymphoma during perichemotherapy was 42.1±16.8, and 30.0% (69/230) patients had obvious dignity impairment. Among 5 dimensions of patient dignity, the scores of physical and mental pain, self-cognition, social role function independence and social support were 1.8±0.8, 1.8±0.9, 1.7±0.9, 1.6±0.7 and 1.2±0.5, respectively. Each patient had an average of 4.1 dignity problems, and five items with the highest score were worrying about their future (physical and mental pain dimension) [(2.1±1.1) scores, 50.4% (116/230)], feeling uncomfortable (physical and mental pain dimension) [(2.0±1.1) scores, 56.5% (130/230)], feeling a burden to others (self-perception dimension) [(2.0±1.1) scores, 33.5% (77/230)], feeling depressed (physical and mental pain dimension) [(1.9±1.0) scores, 53.5% (123/230)], feeling like a different person (self-perception dimension) [(1.9±1.1) scores, 49.1% (113/230)]. Logistic regression analysis showed that widowed (compared with unmarried: OR = 2.108, 95% CI 1.562-3.570), barely affordable and difficult to afford (compared with fully affordable: OR = 2.163, 4.307, respectively; 95% CI 1.120-7.469, 1.374-12.807), disease acceptance and negative (compared with positive: OR = 2.003, 3.694, respectively; 95% CI 1.358-6.599, 1.221-9.061), Eastern Cooperative Oncology Group (ECOG) score 2-4 (compared with score 0: OR = 3.753, 4.720, 5.044, respectively; 95% CI 1.352-9.506, 1.514-12.793, 2.221-15.539), patients with B symptom (compared with those without B symptom: OR = 1.962, 95% CI 1.100-3.501), patients with severe chemotherapy reaction (compared with those without severe chemotherapy reaction: OR = 4.814, 95% CI 2.714-8.539) were independent risk factors for obvious dignity loss of patients during perichemotherapy (all P < 0.05), and married was an independent protective factor compared with unmarried ( OR = 0.192, 95% CI 0.036-0.807, P < 0.05). Conclusion:Patients with lymphoma have impaired dignity during perichemotherapy. Medical staff should pay attention to the influencing factors of impaired dignity and develop targeted intervention programs to reduce the impaired dignity of patients.

Razonamiento clínico en medicina II: hacia una definición integradora / Clinical reasoning in medicine II: Towards an integrating definition

RESUMEN El entendimiento del razonamiento clínico es una necesidad para la investigación, la docencia y la práctica clínica. Los modelos teóricos subyacentes podrían agruparse en tres grandes ejes no excluyentes. El primero es denominado bayesiano informal según su estructura semejante al análisis de probabilidades condicionales. El segundo propone (desde las ciencias cognitivas) un razonamiento dual que es la suma de dos tipos de pensamientos: el tipo 1, rápido e intuitivo y, el tipo 2, hipotético-deductivo. El tercero, el conocimiento intersubjetivo que involucra la interacción del saber del paciente sobre su condición con el del médico, además, de hacer explícito el papel de la emoción. En esta segunda entrega se presenta una revisión narrativa de estas teorías para poder proponer una definición integradora, en la que se presenta al razonamiento clínico como un constructo complejo, iterativo y adaptativo.

SUMMARY Understanding clinical reasoning is a crucial for research, teaching, and daily clinical practice. Theoretical models could be grouped into three main non-exclusive axes. The first describes probability-based thinking, called informal Bayesian, because of its similarity to the conditional probability analysis structure. The second, from the cognitive sciences, describes reasoning as the sum of two types of thinking: type 1 (fast and intuitive) and type 2 (hypothetical-deductive). Finally, the third, intersubjective knowledge, which involves the interaction of the patient's knowledge about his condition with the doctor's knowledge and also makes explicit the role of emotion. In this second part, a narrative review of current theories is presented in order to propose an integrative definition, in which clinical reasoning is presented as a complex, iterative and adaptive construct.

Grieving a disrupted biography: an interpretative phenomenological analysis exploring barriers to the use of mindfulness after neurological injury or impairment.

BACKGROUND: Mindfulness has demonstrated strong utility for enhancing self-management and health outcomes in chronic illness. However, sensation-focused mindfulness techniques may not be appropriate for clinical populations with neurological injury. This study aimed to identify how expert mindfulness teachers with sensory loss/impairment naturalistically adapt and experience mindfulness. We aimed to highlight the rationale for and barriers to mindfulness practice when living with sensory loss. METHODS: A qualitative, semi-structured interview design was used, analysed via Interpretative Phenomenological Analysis (IPA). Eight (5 females, 3 males) mindfulness teachers with neurological injury were recruited via a national registry of Mindfulness for Health teachers. Interviews (range: 50-93 min) were completed, transcribed verbatim and analysed idiographically for descriptive, linguistic and conceptual themes, before a cross-case analysis was completed. RESULTS: Two superordinate themes were identified: (1) Overcoming a disrupted biography; and (2) Proactive self-management. These themes considered the challenge of reconciling, through grief, a past health status with the present reality of living with sensory loss due to Spinal Cord Injury, Multiple Sclerosis or Functional Neurological Disorder. Mindfulness was experienced as a method by which proactive choices could be made to maintain control and autonomy in health, reducing perceptions of suffering, psychological distress, cognitive reactivity and rumination. CONCLUSIONS: Mindfulness was found to support the self-management of health after neurological injury/impairment. Mindfulness meditation presented an initial challenge as trauma and grief processes were (re-)activated during mindfulness sessions. However, mindfulness was found to support the resolution of these grief processes and encourage adaptive approach-based coping and acceptance of health and neurological impairment/injury.

PREVENTING THE PRE-SICK CONDITIONS OF THOSE WHO PRACTICE LIFELONG LEARNING.

OBJECTIVE: The aim: Disclosure of the results of the study of the expediency of considering the fluidity of mental processes in the triad "organism - personality Disclosure of the results of the study of the expediency of considering the fluidity of mental processes in the triad "organism - personality - environment" and the alternate stages of the dynamics of performance to prevent the occurrence of pre-painful conditions in students, combining professional activity with formal education. PATIENTS AND METHODS: Materials and methods: The complex of research methods is used in the work: general scientific (analysis, synthesis, comparison, systematization, generalization) and empirical (observations, discussions, questionnaires). The research was carried out within the framework of the international project "AHIA" (innovation in education; access mode: https://sites.google.com/view/project-axia/). The Spielberger-Hanin questionnaire was used to achieve the stated purpose of the study, the purpose of which was to assess reactive and personal anxiety. RESULTS: Results: The results of a study aimed at organizing a lifelong learning process based on mental processes and stages of performance dynamics showed that the likelihood of pre-painful conditions in those who combine full-time education in higher education with professional activity significantly decreases their self-actualization. Educational events taking place here and now, and recognizing the theoretical and practical significance of the educational material at the level of intrinsic motives. It is established that the likelihood of pre-morbid conditions in those who learn during life significantly increases in the case of reduced functional reserves of their body as a result of the intense and prolonged performance of educational activities with the simultaneous experience of "negatively" colored actual emotional states, generated by activities or events ) experiences of relationships in professional activity, family, family, etc. CONCLUSION: Conclusions: The proposed article describes the effectiveness and appropriateness of using mental processes and stages of performance dynamics as a means to prevent the onset of painful conditions in lifelong learners.