Myofascial release for adults with chronic neck pain and depression.

BACKGROUND: Depression affects a significant portion of the global adult population, with chronic pain patients being particularly susceptible to severe depression. Pain and mental illness contribute to an imbalance in the autonomic nervous system, affecting heart function. Myofascial release promises to improve mental and physical health by addressing fascial dysfunctions. OBJECTIVE: This study aims to investigate the influence of myofascial release on emotional states and autonomic nervous system functioning in individuals with chronic neck pain and depression. Additionally, it seeks to evaluate the myofascial release effect on fascial properties, pain intensity and sensitivity, and cervical spine range of motion. METHOD: Experimental Study. RESULT: The study revealed significant enhancements in the myofascial release group, such as a substantial reduction in pain perception and stiffness, increased range of motion of the cervical spine, heart rate variability, positive affect, and pressure pain threshold. The effect sizes of these improvements ranged from small to large. No significant differences were observed in elasticity and tone. CONCLUSION: The findings suggest that myofascial release has a positive impact on individuals with chronic neck pain and depression, particularly in reducing pain intensity. Integrating myofascial release into treatment approaches may be beneficial. However, further research is needed to confirm and expand upon these findings, explore long-term effects, and better understand the clinical significance of certain outcomes. TRIAL REGISTRATION: http://www.osf.io, doi.org/10.17605/OSF.IO/6F5RS.

Alternative splicing decouples local from global PRC2 activity.

The Polycomb repressive complex 2 (PRC2) mediates epigenetic maintenance of gene silencing in eukaryotes via methylation of histone H3 at lysine 27 (H3K27). Accessory factors define two distinct subtypes, PRC2.1 and PRC2.2, with different actions and chromatin-targeting mechanisms. The mechanisms orchestrating PRC2 assembly are not fully understood. Here, we report that alternative splicing (AS) of PRC2 core component SUZ12 generates an uncharacterized isoform SUZ12-S, which co-exists with the canonical SUZ12-L isoform in virtually all tissues and developmental stages. SUZ12-S drives PRC2.1 formation and favors PRC2 dimerization. While SUZ12-S is necessary and sufficient for the repression of target genes via promoter-proximal H3K27me3 deposition, SUZ12-L maintains global H3K27 methylation levels. Mouse embryonic stem cells (ESCs) lacking either isoform exit pluripotency more slowly and fail to acquire neuronal cell identity. Our findings reveal a physiological mechanism regulating PRC2 assembly and higher-order interactions in eutherians, with impacts on H3K27 methylation and gene repression.

Self-Assessed Experience of Emotional Involvement in Sensory Analysis Performed in Virtual Reality.

Virtual reality (VR) technology has gained significant attention in various fields, including education for health professionals, sensory science, psychology, and consumer research. The first aim of the paper is to explore the self-assessed experience of emotional involvement in sensory analysis performed in VR. The Positive and Negative Affect Schedule (PANAS) is a widely used self-report measure that assesses positive and negative affective states. VR sensory analysis involves the use of immersive, interactive, and multi-sensory environments to evaluate sensory perception and emotional responses. By synthesizing relevant literature, this paper provides insights into the impact of VR on affective states, the effectiveness of VR in eliciting emotions, and the potential applications of the PANAS in VR sensory analysis. Furthermore, the second aim of the paper is to uncover the effect of VR sensory evaluation on the participant's emotional states, as it has a significant effect on their evaluations. The results suggest an increase in the sum of positive effects and a decrease in the negative ones. Although these results are promising, the relationship between the PANAS and VR sensory analysis is still underexplored, with limited research investigating the specific effects of VR on affective states measured using the PANAS. Further research is needed to better understand the potential of the PANAS in assessing emotional responses in VR environments and its implications for sensory analysis.

Affectivity in danish patients with emotional disorders: assessing the validity of the Positive and Negative Affect Schedule (PANAS).

BACKGROUND: The Positive and Negative Affect Schedule (PANAS) was designed to measure trait positive affect (PA) and trait negative affect (NA). METHODS: The Danish PANAS was administered to outpatients with depression and anxiety disorders. Internal consistency was assessed using Cronbach's alpha and McDonald's omega and factorial structure was evaluated using confirmatory factor analysis (CFA). Convergent validity was evaluated by means of correlations with the negative affectivity and the detachment domain of the Personality Inventory for DSM-5 Short Form (PID-5-SF), the Hamilton Anxiety Rating Scale 6 (HARS-6) and the Hamilton Depression Rating Scale 6 (HDRS-6). RESULTS: PANAS Scores of 256 patients were analyzed. Cronbach's alpha and McDonald's omega showed good internal consistency for both the PA score (alpha = .84 and omega = .89) and the NA score (alpha = .86 and omega = .90). CFA analysis confirmed a structure with two factors corresponding to the PA and NA factors. PA was negatively correlated with the detachment domain of PID-5 (r = -.47), HARS-6 (r = -.15) and HDRS-6 (r = -.37). NA was positively correlated with PID-5-SF negative affectivity domain (r = .43), HARS-6 (r = .51) and HDRS-6 (r = .52). DISCUSSION: The Danish PANAS has promising internal consistency and construct validity, which are comparable to other studies of the instrument.

A pilot exploration of the relationships between optimism, affect, and cardiovascular reactivity.

Introduction: Cardiovascular reactivity refers to changes in blood pressure and heart rate in response to internal or external stimuli. Previous research has shown that excessively high and low cardiovascular reactivity are associated with an increased risk of cardiac problems. Dispositional optimism has been associated with numerous health benefits, including better cardiovascular responses to stressors, and reduced mortality risk. Conversely, pessimism has been associated with negative health outcomes and worse cardiovascular reactivity to stress. Mood, comprising positive and negative affect, can significantly impact psychological adjustment and physical health. Therefore, it is important to consider mood as a potential confounding variable in the link between optimism and cardiovascular reactivity. The study hypothesized that optimism and pessimism would still influence cardiovascular reactivity even when mood variables were controlled for. Methods: A within-subjects correlational design with 107 young adult participants was used. Sociodemographic and clinical questionnaires were administered to collect information on participants' characteristics. The Dispositional Optimism Scale (LOT-R) and the Positive and Negative Affect Scale (PANAS) were used to assess participants' levels of optimism, pessimism, and mood. Measures of cardiovascular reactivity, including systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR), were taken during a stressor task (PASAT). Results: There is a moderate positive correlation between dispositional optimism and positive affect, while pessimism demonstrated a moderate positive association with negative affect. Linear regression analyses were conducted, controlling baseline reactivity variables, gender, and body mass index. The results showed that pessimism had a significant negative effect on SBP reactivity, suggesting that higher levels of pessimism decreased SBP response. Optimism had a significant positive effect on DBP reactivity, while pessimism had a significant negative effect. Discussion: Overall, these results suggest that dispositional optimism and pessimism are related to cardiovascular reactivity, even after controlling for positive and negative affect. Pessimism was associated with lower SBP reactivity, while both optimism and pessimism influenced DBP reactivity. These findings are consistent with previous research indicating that optimism enables more effective stress management during challenging events, whereas pessimism can serve as a risk factor, heightening the likelihood of experiencing future cardiac issued caused by blunted cardiovascular reactivity.

Ability Emotional Intelligence and Subjective Happiness in Adolescents: The Role of Positive and Negative Affect.

Adolescence is an increasingly vulnerable period for the onset of affective disorders and other mental health issues that can significantly impact an individual's subjective well-being. This study aims to examine the relationship between emotional intelligence (ability EI), measured with a performance-based instrument, and Subjective Happiness in adolescents. It also explores the mediating role of positive (PA) and negative affect (NA) in this association and the moderating role of gender. The sample consisted of 333 first-year secondary school students from five centers in Spain, with an average age of 12.11 years (SD = 0.64), ranging from 11-14 years. Path analysis revealed an indirect effect (through NA and PA jointly) of Total Ability EI on Subjective Happiness and a positive direct effect that was observed only in females. Furthermore, this association was explored through various branches of ability EI. The results of this study suggest that interventions aimed at improving emotional abilities in adolescents while modulating the intensity of their emotions could significantly impact their overall well-being.

Effects of a Service-Learning Neuroscience Course on Mood and Intergroup Anxiety.

"Everyday Neuroscience" is an academically based community service (ABCS) course in which college students teach basic neuroscience lab activities to high school students in an under-funded school district, working in small groups on hands-on science activities for 10 weekly sessions. The present study examined the possible psychological and social effects of this experience on the college students, in comparison with peers not enrolled in such a course, by observing and surveying the high school and college students across the 10-week course period. First, the teaching-learning sessions in the course successfully promoted science-focused discussion between the high school and college students for 45 to 60 minutes each week. Second, college students in "Everyday Neuroscience" reported higher positive affect and less intergroup anxiety at the end of the semester compared with the control group of college students who were not in the course. Finally, surveys of the high school students revealed that they found the sessions to be positive social experiences. These findings reveal that a neuroscience-based community engagement course can be both a positive experience for the community partner and a benefit for college students by promoting psychological and social wellness.

Quantitative indicators of street lighting with mood, fatigue, mental workload and sleepiness in car drivers: Using generalized structural equation modeling.

Inadequate lighting will be associated with some degree of perceptual error such as sleepiness. The main purpose of this study was to investigate the interactions between mood, fatigue, mental workload, and sleepiness and their relationship with quantitative indicators of street lighting in passenger car drivers. The present study was a cross-sectional study that was performed on 270 drivers of passenger cars. The quantitative indices of lighting studied were illuminance, luminance, uniformity, and disability glare which were calculated using the Hagner device (EC1-L) and according to EN 13201 standard. Alertness and mood indices, fatigue scale (SAMN-PERELLI), mental workload (NASA-TLX), positive and negative affect schedule (PANAS) were used. Generalized structural equation modeling (GSEM) was used to investigate the relationship between mood, fatigue, mental workload, and drivers' sleepiness. Data analysis was performed in version 26 of SPSS software and version 14 of Stata software There is a significant relationship between illuminance and mood (P < 0.001). There is a significant relationship between the degree of disability glare on the streets and the mood (P = 0.006). There is a significant relationship between fatigue score and mood (P < 0.001) so that with increasing one unit in fatigue scale, mood score decreases by 0.669 units (P < 0.001). Finally, it can be assured that lighting interventions can be done as an effective way to increase alertness and reduce fatigue and the mental workload of drivers with the aim of reducing night traffic accidents.

VisualEars: How an immersive art exhibit impacts mood during the COVID-19 pandemic.

This paper explores the positive impact of viewing a virtual art exhibit on mood during the COVID-19 Pandemic. During global lockdowns, depression, anxiety, and the burden of other mental illnesses have increased even among prior psychiatrically healthy individuals. Art and music-based interventions have shown to be effective clinical interventions in individuals with mental illness. The VisualEars project explored whether a virtual activity involving vision and auditory stimuli could improve positive and negative affect. Eight musical pieces were selected, and 28 visual artists from around the world visualized two musical pieces. A total of 56 works of art were created and hung in eight 3D virtual rooms. Visitors were randomly selected to either view the art exhibit without music (non-immersive) or view the art exhibit while listening to music (immersive). Visitors were asked to complete a positive and negative affect schedule (PANAS) in three languages (English, French, and Farsi) pre and post their virtual visit. A total of 160 participants completed baseline PANAS, 58 of which completed the follow-up PANAS. Linear mixed-effects models found that older participants had lower negative affect scores overall (b = -0.3, p = 0.003), while male participants had lower positive affect scores overall (b = -0.27, p = 0.02). Following the virtual exhibit participants of both conditions had higher positive (b = 0.17, p = 0.03), and lower negative affect scores (b = -0.19, p = 0.007). We found that the virtual art exhibit increased positive affect and decreased negative affect in participants, suggesting an overall improvement in mood attributable to the virtual exhibit. This suggests that virtual exhibits may serve as a beneficial and accessible intervention to improve mood during a pandemic.

The experimental effect of social media use, treadmill walking, studying, and a control condition on positive and negative affect in college students.

Using a within-subjects design, this study assessed the experimental effect of common activities upon positive and negative affect scores in a college student sample. All participants completed the following 30-minute activity conditions: treadmill walking, self-selected schoolwork (i.e., studying), social media use, and a control condition where participants sat in a quiet room (i.e., do nothing). Positive and negative affect scores were assessed at baseline, mid-, and post-condition. Positive affect scores increased by 26% and 10% during the treadmill and studying conditions, respectively. Conversely, positive affect decreased by 20% and 24% during the social media and "do nothing" conditions, respectively. Furthermore, negative affect was decreased by 8% in the studying condition. These changes were statistically significant (p ≤ 0.04). This suggests that college students' everyday activities can significantly impact affect, for better and for worse. As demonstrated, studying and walking may improve affect, whereas social media use may negatively impact affect.

The Psychological Mechanisms Underlying Solomon's Paradox: Impact of Mood and Self-Transcendence.

Solomon's paradox of wise reasoning, in which performance of wisdom differs when reasoning on an issue in one's own life vs. another's life, has been supported by robust evidence. However, the underlying psychological mechanism remains unclear. This asymmetry of wise reasoning may be explained by the different mindsets of self-transcendence when people reason about various conflicts (personal vs. others'), and mood should play a fundamental role. To explore this issue, three hundred ninety-nine participants were recruited to test a hypothesized model. The results supported the effect of Solomon's paradox-that is, participants endorsed wise-reasoning strategies more strongly when resolving others' social conflicts than their own. Further mediation analysis showed that the sequential mediation model was supported. Solomon's paradox can be explained by the difference in positive affect and self-transcendence when reasoning about the two conflicts. This study directly verifies the mediating role of self-transcendence in Solomon's paradox. At the same time, reasoning about personal affairs reduces individuals' self-transcendence mindset, and positive affect can explain the differences. These results are helpful for understanding and effectively avoiding Solomon's wisdom dilemma.

Relationship between psychosocial stress-induced prefrontal cortex activity and gut microbiota in healthy Participants-A functional near-infrared spectroscopy study.

Brain and gut microbes communicate in a bidirectional manner with each affecting a person's response to psychosocial stress. Although human studies demonstrated that the intake of probiotics can alter stress-related behavior in both patients and healthy participants, the association between stress-related brain functions and the gut microbiota has mostly been investigated in patients with depression. However, the response to psychosocial stress differs, even among healthy individuals, and elucidating the natural state of the gut microbiota would broaden the understanding of responses to psychosocial stress. We investigated the relationship between psychosocial stress response in the prefrontal cortex and the abundance of gut microbes in healthy male participants. The participants were exposed to psychosocial stress during a task while brain activation data were recorded using functional near-infrared spectroscopy. The heart rate and subjective stress were recorded, and fecal samples were collected. The stressful condition was accompanied by high subjective stress, high heart rate, and higher prefrontal activation in the right pre-motor cortex/supplementary motor area, right dorsolateral prefrontal cortex, right frontal pole, and right inferior prefrontal gyrus. The psychosocial stress response in the prefrontal cortex was also associated with changes in the gut microbiota abundance. The abundance of Alistipes, Clostridium IV, Clostridium XI, Faecalibacterium, and Blautia in healthy participants who had high psychosocial stress resembled that noted in patients with depression. These results suggest that the gut microbiota differs, among healthy participants, depending on the psychosocial stress response. We believe that this study is the first to report a direct relationship between brain function and the gut microbiota in healthy participants, and our findings would shed a new light on this field in the near future.

Identification of Mood and Body Mass Index as Modifiable Factors for Health Improvement in Spinal Cord Injury.

Objective: To examine the link between body mass index (BMI) and positive and negative affect after spinal cord injury (SCI). Design: Cross-sectional study. Setting: Inpatient and outpatient services of a rehabilitation department in Delhi, India. Participants: Individuals (N=142) with spinal cord injury participated in the study. Interventions: None. Main Outcome Measures: Participants were asked to rate their affect using the Positive and Negative Affect Schedule. BMI was assessed with an SCI-specific procedure. Demographic and injury-related details (eg, level, nature, chronicity) were taken. Results: As expected, BMI negatively correlated with positive affect (r=-1.70; P=.043). Furthermore, the chances of younger individuals with SCI having a lower BMI is 3.49 times the odds of the older individuals having a low BMI (odds ratio [OR], 3.491; 95% confidence interval [CI], 1.520-8.018). The chances of men having low affect was higher than women (OR, 2.55; 95% CI, 1.08-6.04). Conclusions: Higher BMI might be associated with lower positive affect and contribute to a higher risk of depression, specifically in women with SCI. These results might be used to enhance the regulation of physical activity (exercises) and affect experiences through therapeutic activities and proactive counselling for individuals with SCI.

Limited negative effects of the COVID-19 pandemic on mental health measures of Ghanaian university students.

BACKGROUND: Stress and mental health outcomes are negatively correlated among university students throughout the world. Reports of differences in stress perception by gender exist, but there is limited data on students from sub-Saharan African countries. This study describes the burden of perceived and financial stress; characterizes mood and degree of anxiety symptoms; examines stress coping mechanisms, including resilience and repetitive negative thinking (RNT); and explores how students at a Ghanaian university believed the COVID-19 pandemic affected these measures. METHODS: Students (n = 129) were recruited from the Kwame Nkrumah University of Science and Technology, Kumasi, Ghana from October 2020 - January 2021. Validated surveys were used. Participants were asked "Are your answers to the questions affected by the COVID-19 pandemic?" RESULTS: No differences in mean scores were observed between genders. For female students, financial stress was positively associated with RNT (p = 0.009), negative mood (p = 0.002), and anxiety (p < 0.001). Males were more likely to report decreased stress during the pandemic (p = 0.002), but there was no difference in mental health outcomes by perceived stress (PS) change category among males. Effects of the pandemic on mental health outcomes were mixed, but substantial proportions of students reported improvements or no change in financial stress, mood, anxiety, and RNT. LIMITATIONS: Students from one university particiapted in this cross-sectional survey. CONCLUSIONS: This study adds to the understanding of how higher education students are experiencing stress and are coping with the uncertainties of the COVID-19 pandemic in Ghana.

Using AI chatbots to provide self-help depression interventions for university students: A randomized trial of effectiveness.

BACKGROUND: Depression impacts the lives of a large number of university students. Mobile-based therapy chatbots are increasingly being used to help young adults who suffer from depression. However, previous trials have short follow-up periods. Evidence of effectiveness in pragmatic conditions are still in lack. OBJECTIVE: This study aimed to compare chatbot therapy to bibliotherapy, which is a widely accepted and proven-useful self-help psychological intervention. The main objective of this study is to add to the evidence of effectiveness for chatbot therapy as a convenient, affordable, interactive self-help intervention for depression. METHODS: An unblinded randomized controlled trial with 83 university students was conducted. The participants were randomly assigned to either a chatbot test group (n = 41) to receive a newly developed chatbot-delivered intervention, or a bibliotherapy control group (n = 42) to receive a minimal level of bibliotherapy. A set of questionnaires was implemented as measurements of clinical variables at baseline and every 4 weeks for a period of 16 weeks, which included the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder scale (GAD-7), the Positive and Negative Affect Scale (PANAS). The Client Satisfaction Questionnaire-8 (CSQ-8) and the Working Alliance Inventory-Short Revised (WAI-SR) were used to measure satisfaction and therapeutic alliance after the intervention. Participants' self-reported adherence and feedback on the therapy chatbot were also collected. RESULTS: Participants were all university students (undergraduate students (n = 31), postgraduate students (n = 52)). They were between 19 and 28 years old (mean = 23.08, standard deviation (SD) = 1.76) and 55.42% (46/83) female. 24.07% (20/83) participants were lost to follow-up. No significant group difference was found at baseline. In the intention-to-treat analysis, individuals in the chatbot test group showed a significant reduction in the PHQ-9 scores (F = 22.89; P < 0.01) and the GAD-7 scores (F = 5.37; P = 0.02). Follow-up analysis of completers suggested that the reduction of anxiety was significant only in the first 4 weeks. The WAI-SR scores in the chatbot group were higher compared to the bibliotherapy group (t = 7.29; P < 0.01). User feedback showed that process factors were more influential than the content factors. CONCLUSIONS: The chatbot-delivered self-help depression intervention was proven to be superior to the minimal level of bibliotherapy in terms of reduction on depression, anxiety, and therapeutic alliance achieved with participants.

Factor Structure of the PANAS With Bayesian Structural Equation Modeling in a Chinese Sample.

The Positive and Negative Affect Schedule (PANAS) is the most widely used self-report instrument for assessing affect. However, there are inconsistent findings regarding the factor structure of the PANAS. In this study, we applied Bayesian structural equation modeling (BSEM) to investigate the structure of the PANAS using data from a sample of 893 Chinese middle and high school students. Four models, the orthogonal two-, the oblique two-, the three-, and the bi-factor models were tested with prior specifications including approximately zero cross-loadings and residual covariances. The results indicated that the orthogonal two-factor model specified with informative priors for both cross-loadings and residual correlations has the best model fit. Confirmatory factor analysis with the maximum likelihood estimator (ML-CFA) based on modifications from BSEM analysis showed improved model fit compared to ML-CFA based on frequentist analysis, which is the evidence for the merit of BSEM for addressing misspecifications.

Physical activity during the SARS-CoV-2 pandemic is linked to better mood and emotion.

The SARS-CoV-2 pandemic may negatively impact mood and emotion. Physical activity may protect against mood disturbance and promote positive affect. This study asked if physical activity before, during, or the change in physical activity with the pandemic, impacted affect and mood during the pandemic. US adult residents (18-74 years; N = 338) were surveyed from 29 April to 3 June 2020. Physical activity before and during the pandemic was assessed with the Physical Activity Rating survey. The Positive and Negative Affect Schedule measured affect and the Profile of Moods Questionnaire assessed mood. Comparisons between physically inactive and active participants by Analysis of Covariance found greater vigour in participants classed as physically active before the pandemic. Positive affect, vigour and esteem-related affect were greater in participants physically active during the pandemic. Multiple linear regression revealed relationships between the change in physical activity and mood. Change in physical activity positively associated with positive affect (b = 1.06), esteem-related affect (b = 0.33) and vigour (b = 0.53), and negatively associated with negative affect (b = -0.47), total mood disturbance (b = -2.60), tension (b = -0.31), anger (b = -0.24), fatigue (b = -0.54), depression (b = -0.50) and confusion (b = -0.23). These data demonstrate that physical activity during the pandemic, and increased physical activity relative to before the pandemic, related to better mood.

Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: Study protocol for a randomized controlled trial.

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program includes 8 modules, and it is based on motivational interviewing, cognitive-behavioral therapy (CBT), and extensions and innovations of CBT. It includes several complementary tools that are present throughout the entire intervention. Therapeutic support will be provided once a week through a phone call with a maximum length of 10 min. The primary outcome measure will be gambling severity and gambling-related cognitions, and secondary outcome measures will be readiness to change, and gambling self-efficacy. Other variables that will be considered are depression and anxiety symptoms, positive and negative affect, difficulties in emotion regulation strategies, impulsivity, and quality of life. Individuals will be assessed at baseline, post-treatment, and 3-, 6-, and 12-month follow-ups. During the treatment, participants will also respond to a daily Ecological Momentary Intervention (EMI) in order to evaluate urges to gamble, self-efficacy to cope with gambling urges, gambling urge frequency, and whether gambling behaviour occurs. The EMI includes immediate automatic feedback depending on the participant's responses. Treatment acceptance and satisfaction will also be assessed. The data will be analysed both per protocol and by Intention-to-treat. As far as we know, this is the first randomized controlled trial of an online psychological intervention for gambling disorder in Spain. It will expand our knowledge about treatments delivered via the Internet and contribute to improving treatment dissemination, reaching people suffering from this problem who otherwise would not receive help. TRIAL REGISTRATION: Clinicaltrials.gov as NCT04074681. Registered 22 July 2019.

Communication outside of the home through social media during COVID-19.

This study explored, through quantitative and qualitative survey analysis (N = 307), the role of communication through social media during the COVID-19 pandemic. Data were collected in April 2020 to understand how individuals engaged with their network through social media and the subsequent relationship with subjective well-being, conceptualized as loneliness, life satisfaction, and positive and negative affect. Results identified that passive social media use contributed to greater loneliness and a decrease in life satisfaction. Some active use of social media contributed to an increase in positive affect. However, other active uses increased feelings of loneliness. Results also spoke to differences across platforms, with time on Twitter leading to increased feelings of loneliness. Qualitative results pointed to an increase in social media use during the pandemic while also highlighting the opportunity to digitally reconnect with old friends and family.

Qualitative Impressions of a Yoga Nidra Practice for Insomnia: An Exploratory Mixed-Methods Design.

Introduction: Insomnia affects up to half of the U.S. population, and due to limitations of current treatments, there is a growing interest in mind-body practices to reduce insomnia. To understand how a guided meditation practice, Yoga Nidra, may affect relaxation and align with current descriptions of nonpharmaceutical practices that could improve sleep, qualitative and quantitative methods were used to explore participant experience of a single Yoga Nidra practice, administered in a group setting. Methods: Current insomnia (Insomnia Severity Index), sleep practices, and mood (positive and negative affect schedule [PANAS]) were measured at intake. After 30 min of Yoga Nidra practice, the PANAS was readministered. In a focus group that followed, participants discussed their experience before, during, and after the practice and the likelihood of repeating it. Six groups were conducted. All interested adults were welcome to join. Results: In the final sample of 33 individuals (79% female), 80% of participants reported insomnia at intake and 45% reported a regular mind-body practice, supporting the prevalence of insomnia in the society as well as the interest in mind-body practices. After the Yoga Nidra intervention, mean negative affect decreased 5.6 ± 4.5 points, a 31% decrease from baseline, and positive affect decreased 3.5 ± 9.7 points, a 13% decrease. Three major themes were identified from focus group discussions: response to the practice (relaxation, perceived sleep, and sense withdrawal); factors that affect engagement (delivery method and intrapersonal factors); and potential as a clinical intervention (for conditions including sleep, anxiety, and pain). Conclusion: Yoga Nidra appeared tolerable within the sample, and descriptions suggest it may be useful for enhancing relaxation, facilitating sleep, easing anxiety, and reducing pain. Results from this study will inform the design of future studies of Yoga Nidra for insomnia and related conditions.