Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse.

The anti-inflammatory and immunosuppressive properties of steroids allow their use in a wide variety of rheumatological diseases, asthma, inflammatory bowel disease, cancer therapy, and severe viral infections. Though life-saving or organ-saving, long-term clinical use leads to a vast array of complications. Osteoporosis is the most common orthopedic side effect of steroid abuse, while osteonecrosis is a rare occurrence. The risk of osteonecrosis appears to be dose and duration dependent, but several patient factors also play a major role and usually affect the femoral head followed by the knee joint. The long-term effects of steroids must be explained to all patients on therapy, but this risk is missed in individuals who abuse steroids for recreational or performance-enhancing purposes. We describe a male, aged 29 years, who presented with dull aching bilateral knee pain of 2-years' duration after a long-term steroid abuse for weight and muscle mass gain. Radiological and magnetic resonance imaging studies confirmed osteonecrosis of femoral and tibial condyles and secondary degenerative arthritis of the knee joint. Prompt suspicion, early diagnosis, and intervention in osteonecrosis of knee joints, and termination of steroids may reverse the pathology and prevent progression of disease.

Superior bioavailability of the calcium salt form of ß-hydroxy-ß-methylbutyrate compared with the free acid form.

We investigated the bioavailability of the calcium salt (HMB-Ca) and the free acid (HMB-FA) forms of ß-hydroxy-ß-methylbutyrate (HMB). Sixteen young individuals received the following treatments on three different occasions in a counterbalanced crossover fashion: (1) HMB-FA in clear capsules; (2) HMB-Ca in gelatine capsules; (3) HMB-Ca dissolved in water. All treatments provided 1 g of HMB. Blood samples were taken before and on multiple time points following ingestion. The following parameters were calculated: peak plasma (Cmax), time to peak (Tmax), slope of HMB appearance in blood, area under the curve (AUC), half-life time (t1/2) and relative bioavailability (HMB-Ca in water set as reference). All treatments led to rapid and large increases in plasma HMB. HMB-Ca in capsules and in water showed similar plasma HMB values across time (p = 0.438). HMB-FA resulted in lower concentrations vs. the other treatments (both p < 0.001). AUC (HMB-Ca in capsules: 50,078 ± 10,507; HMB-Ca in water: 47,871 ± 10,783; HMB-FA: 29,130 ± 12,946 µmol L-1 × 720 min), Cmax (HMB-Ca in capsules: 229.2 ± 65.9; HMB-Ca in water: 249.7 ± 49.7; HMB-FA: 139.1 ± 67.2 µmol L-1) and relative bioavailability (HMB-Ca in capsules: 104.8 ± 14.9%; HMB-FA: 61.5 ± 17.0%) were lower in HMB-FA vs. HMB-Ca (all p < 0.001). HMB-Ca in water resulted in the fastest Tmax (43 ± 22 min) compared to HMB-Ca in capsules (79 ± 40 min) and HMB-FA (78 ± 21 min) (all p < 0.05), while t1/2 was similar between treatments. To conclude, HMB-Ca exhibited superior bioavailability compared to HMB-FA, with HMB-Ca in water showing faster absorption. Elimination kinetics were similar across all forms, suggesting that the pharmaceutical form of HMB affects the absorption rates, but not its distribution or elimination.

Performance-enhancing substances in sport: A scientometric review of 75 years of research.

The use of performance-enhancing substances not only undermines the core values of sports but also poses significant health risks to athletes. In a fast-evolving doping environment, where sport professionals are constantly seeking novel and illegal means to bypass doping tests, and new substances are regularly detected on the drug market, it is crucial to inform authorities with updated evidence emerging from scientific research. The current study aims to (i) outline the structure of knowledge in the literature on performance enhancers in sports (i.e., most active countries, main sources, most productive authors, and most frequently used keywords); (ii) identify the most impactful documents in the field; and (iii) uncover the main domains of research in the literature. To do so, we conducted a comprehensive scientometric analysis of the literature on doping, sourcing our data from Scopus. Our research involved a document co-citation analysis of 193,076 references, leading to the identification of the 51 most influential documents and seven key thematic areas within the doping literature. Our results indicate that the scientific community has extensively studied the most prevalent doping classes, such as anabolic agents and peptide hormones, and little is still known about the use of contaminated supplements or other types of enhancers identified as emergent trends. Concurrently, technological advancements contributed to the development of more sophisticated doping detection techniques, using blood or urine samples. More recently, the focus has shifted towards the athlete biological passport, with research efforts aimed at identifying biomarkers indicative of doping. The dynamic nature of doping methods underlines the necessity for more robust educational campaigns, aiming at raising awareness among sports professionals and their entourage about the dangers of doping and the intricacies of its control mechanisms.

The Effect of Oral Adenosine Triphosphate (ATP) Supplementation on Anaerobic Exercise in Healthy Resistance-Trained Individuals: A Systematic Review and Meta-Analysis.

Adenosine triphosphate (ATP) is an energy and signaling molecule. It is synthesized endogenously and can be taken as an oral supplement. This review aimed to identify the effects of oral ATP supplementation on anaerobic exercise in healthy resistance-trained adults. A systematic review and meta-analysis were performed based on the Preferred Reporting Items of Systematic Reviews and Meta-Analysis (PRISMA) criteria. The inclusion criteria were articles published from 2000 to 2022, with anaerobic variables (maximal strength, maximum repetitions, and maximum anaerobic power) measurable in healthy adults with experience in resistance training, only randomized placebo-controlled clinical trials (RCTs), and with the acute (a single dose 30 min to 24 h before the tests) and/or chronic (>1 day) oral supplementation of ATP. A total of five RCTs with 121 adult men were included. The oral ATP supplementation achieved significantly greater gains in maximal strength compared with the placebo (PL) (MD = 8.13 kg, 95%CI [3.36-12.90], p < 0.001). Still, no differences were observed in the maximum number of repetitions or the maximum anaerobic power. Furthermore, 400 mg of ATP showed improvement in anaerobic exercise regardless of the duration of the supplementation protocol. In conclusion, supplementation with 400 mg of ATP doses can improve maximal muscle strength in resistance-trained men.

Perfectionism and doping willingness in athletes: The mediating role of moral disengagement.

Although trait perfectionism has been related to doping attitudes in athletes, research investigating variables that could account for relationships between perfectionism and doping outcomes has received scant attention. Consequently, the aim of the present study was to investigate whether perfectionism was related to doping willingness directly, and indirectly via moral disengagement. We recruited a sample of 204 student athletes (M age = 19.12 years, SD = 1.17, n = 81 females - 39.70%) who completed measures of perfectionistic strivings, perfectionistic concerns, doping moral disengagement, and doping willingness. Multiple regression analyses revealed a significant positive relationship between perfectionistic concerns and doping willingness (ß = .13, p < .05) and a nonsignificant relationship between perfectionistic strivings and doping willingness (ß = -.01, p > .05). Moreover, bias-corrected bootstrapped indirect effects revealed that doping moral disengagement mediated the relationship between perfectionistic concerns and doping willingness (ab = .12; 95% CI = 0.02 to 0.21). The findings suggest that the relationship between perfectionistic concerns and doping extends beyond attitudes - to doping willingness - and the propensity to morally disengage explains why this is the case.

Bodybuilding: A Comprehensive Review of Performance-Enhancing Substance Use and Public Health Implications.

The use of performance-enhancing substances in bodybuilding is a well-known and long-standing issue. This comprehensive review article provides a detailed overview of the history of performance-enhancing substance use in bodybuilding, the types of substances commonly used, and the short-term and long-term health effects associated with their use. Additionally, the article discusses the regulation of performance-enhancing substances in various countries and the role of healthcare professionals in preventing substance use. The article also highlights the impact of substance use on society and the importance of prevention and intervention strategies. Finally, the article emphasizes the role of policymakers in addressing performance-enhancing substance use, including the development of regulations, penalties for violating rules, and the provision of resources for prevention and intervention programs. Overall, this review article sheds light on the dark side of bodybuilding and provides insight into the public health implications of performance-enhancing substance use.

Doping in Sport-Attitudes of Physical Trainers Students Regarding the Use of Prohibited Substances Increasing Performance.

BACKGROUND: The popularity of using the advice of a personal trainer is increasing in Poland and currently most gyms offer the possibility of training under the supervision of a professional. Personal trainers present a multifaceted nature into physical activity and become their clients' guides in achieving sporting goals. Physical trainers also work in sports clubs and supervise the training of people professionally involved in sport. AIM: Given the professional role that they play, this article aimed to analyze the knowledge and attitudes of personal trainers towards using prohibited measures to improve performance in sport, as well as counteraction measures. METHODS: The study used a questionnaire created by the authors containing closed, semi-open, and open questions. RESULTS: The results of the presented research indicate that most physical trainers and students educated in this field have a negative attitude towards the use of prohibited measures that increase performance but they noticed that doping was common in sport by 88.51% respondents. In the group of personal trainers, the majority (87.14%) admitted that good results in sport could be achieved without the use of doping. They stated that it was unfair (25%), contrary to the fair play principle-16%, while over 11% indicated this as cheating. Only 6% of people pointed out that it was legally prohibited and 3% that it was harmful. These results show that 10.13% of all respondents believe that the use of doping is a necessity to achieve very good results in sport. CONCLUSIONS: The availability of doping substances is statistically correlated with the question of persuading to use doping in both groups of trainers and students and some people justify the use of doping. The research proved that the personal trainers' level of knowledge on doping is still insufficient.

Are Dietary Supplements a Gateway to Doping? A Retrospective Survey of Athletes' Substance Use.

Background: It is proposed that the use of dietary supplements might lead to the use of doping substances. This has been termed the gateway hypothesis. However, within an athletic sample, no research has examined the order in which these substances are consumed and what may explain the progression from dietary supplement use to doping. Objective: To identify whether dietary supplement use precedes doping and examine what moderates the dietary supplement-doping relationship. Methods: Competitive athletes (N=1,081, 42.0% female; Age=29.3±10.8 years) completed an online survey measuring dietary supplement use, doping use, doping subjective norms and age of using a supplement and/or doping substance. Results: Dietary supplement users were 11 times more likely to dope than non-users (OR=11.28, 95% CI = 2.72 to 46.77). Age for first use of a dietary supplement was younger than use of a doping substance (mean difference=-4.5±5.1 years old, p<0.001, d=0.90). Over three-quarters of doping users reported using a dietary supplement first (77.1%), whereas a small proportion of athletes started using dietary supplements and doping at the same time (12.5%) and some used doping substances before using dietary supplements (10.4%). Moderation analysis revealed that dietary supplement users may be more likely to dope because of a more favourable social acceptance of using prohibited substances than non-users. Conclusions: Data suggest that dietary supplement use is more likely to precede doping. However, not all doping users begin with using dietary supplements, which highlights the importance of measuring the temporal order of dietary supplement and doping use in future research.

Effects of Capsaicin and Capsiate on Endurance Performance: A Meta-Analysis.

Several studies have explored the effects of capsaicin and capsiate on endurance performance, with conflicting findings. This systematic review aimed to perform a meta-analysis examining the effects of capsaicin and capsiate vs. placebo on endurance performance in humans. Seven databases were searched to find eligible studies. The effects of capsaicin and capsiate on aerobic endurance (e.g., time-trials or time-to-exhaustion tests), muscular endurance (e.g., repetitions performed to muscular failure), and rating of perceived exertion (RPE) were examined in a random-effects meta-analysis. Fourteen studies (n = 183) were included in the review. Most studies provided capsaicin or capsiate in the dose of 12 mg, 45 min before exercise. In the meta-analysis for aerobic endurance, there was no significant difference between the placebo and capsaicin/capsiate conditions (Cohen's d: 0.04; 95% confidence interval: -0.16, 0.25; p = 0.69). In subgroup meta-analyses, there were no significant differences between the placebo and capsaicin/capsiate conditions when analyzing only studies that used time-trials (p = 0.20) or time-to-exhaustion tests (p = 0.80). In the meta-analysis for muscular endurance, a significant ergogenic effect of capsaicin/capsiate was found (Cohen's d: 0.27; 95% confidence interval: 0.10, 0.43; p = 0.002). When analyzing set-specific effects, an ergogenic effect of capsaicin/capsiate was found in set 1, set 2, and set 3 (Cohen's d: 0.21-29). Capsaicin/capsiate ingestion reduced RPE following muscular endurance (p = 0.03) but not aerobic endurance tests (p = 0.58). In summary, capsaicin/capsiate supplementation acutely enhances muscular endurance, while the effects on aerobic endurance are less clear.

Do empreendedor de si mesmo à medicalização da performance: reflexões sobre a flexibilização no mundo do trabalho / From being entrepreneur of the self to the medicalization of performance: reflections upon labour market flexibilization

Resumo O presente ensaio crítico-reflexivo busca discutir a medicalização da performance a partir de reflexões sobre a flexibilização no mundo do trabalho e o fenômeno do empreendedorismo de si. Em um contexto de financeirização da economia, reestruturação produtiva e fragilização do Estado como esfera garantidora dos direitos sociais, impera a precarização e a informalidade, onde a flexibilização do trabalho ocorre em consonância com estratégias político-ideológicas de inspiração neoliberal. Emergem então, modos de individualização atrelados à construção de um trabalhador disposto a desenvolver variadas habilidades, que passa a ser um potencial empreendimento e ter como princípio a mesma dinâmica mercadológica deste. O empreendedor de si mesmo precisa investir em si para manter-se valorizado e em boas condições de funcionamento, de modo a evitar a sua descapitalização. Para dar condições ao sujeito de sustentar a imagem de sucesso e de autor de sua própria história, a utilização de medicamentos, estimulantes e polivitamínicos, tem sido usada como estratégia em busca de alta performance. Problematizar os "empreendedores de si", as novas formas de subjetivação e o sofrimento advindo destas, bem como a maquinaria que os produzem é necessário, e se constitui um desafio para a saúde coletiva.

Abstract This critical-reflective essay seeks to discuss the medicalization of performance based on reflections on flexibility in the world of work and the phenomenon of self-entrepreneurship. In a context of economy financialization, productive restructuring and State's weakening as guarantor of social rights, precarization and informality are increasingly prevailing, where the promotion of labour flexibilization occurs in line with political-ideological strategies of neoliberal inspiration. There emerge ways of individualization tied to the construction of a multifunctional worker, available to develop multiple abilities, which becomes a potential enterprise and has as a principle the same market dynamics as this enterprise. The entrepreneur of the self needs to invest in itself to keep being valuable and having great functioning conditions, in order to avoid, to the fullest, its own decapitalization. Therefore, in order to enable conditions to sustain the image of success and of author of its own story, the usage of medicines, stimulants and multivitamins has been used as a strategy in search of high performance. To reflect on "the entrepreneur of the self", the new ways of subjectivity and the suffering derived from those, as well as the apparatus that produces them, is necessary and consists in a challenge for community health.

Muscle-building behaviors from adolescence to emerging adulthood: A prospective cohort study.

This study aimed to identify patterns of change in muscle-building behaviors from adolescence to emerging adulthood and determine what adolescent factors predict new-onset muscle-building behavior in emerging adulthood. Prospective cohort data from a diverse sample of 1,535 participants followed from adolescence (baseline, M age = 14.4 ± 2.0 years) to emerging adulthood (follow-up, M age = 22.1 ± 2.0 years) from the population-based EAT 2010-2018 (Eating and Activity over Time) study were analyzed. Changes in muscle-building behavior were identified (starting, stopping, persistent use, or never use). Log-binomial regression models examined adolescent predictors of starting (i.e., new-onset) muscle-building behaviors in emerging adulthood. Prevalence of any use in adolescence (EAT 2010) and/or emerging adulthood (EAT 2018) was 55.1% (males) and 33.0% (females) for protein powder/shakes, 6.7% (males) and 5.4% (females) for steroids, and 19.4% (males) and 6.5% (females) for other muscle-building substances (e.g., creatine, amino acids). In particular, 22.6% (males) and 13.7% (females) started protein powder/shakes, 2.2% (males) and 1.0% (females) started steroid use, and 9.0% (males) and 2.0% (females) started other muscle-building substances during emerging adulthood. Adolescent protein powder/shake consumption was associated with starting steroids/other muscle-building substances use in emerging adulthood in males (adjusted risk ratio [ARR] 2.09, 95% confidence interval [CI] 1.29-3.39) and females (ARR 4.81, 95% CI 2.01-11.48). Adolescent use of protein powders/shakes may lead to a two- to five-fold higher risk of new use of steroids and other muscle-building products in emerging adulthood. Clinicians, parents, and coaches should assess for use of muscle-building behaviors in adolescents and emerging adults and discourage use of harmful products.

Preliminary Research towards Acute Effects of Different Doses of Caffeine on Strength-Power Performance in Highly Trained Judo Athletes.

Although several previous studies examined the effect of pre-exercise caffeine ingestion on judo-specific performance, the optimal dose of caffeine to maximise the ergogenic effects for judoka is not clear. The main purpose of this study was to analyse the effects of oral administration of 3 and 6 mg/kg of caffeine on a battery of physical tests associated with judo performance. Ten highly trained national-level judoka (6 men and 4 women, age: 24.1 ± 4.7 years, body mass: 73.4 ± 12.9 kg, 15.1 ± 5.2 years of judo training experience, 2.6 mg/kg/day of habitual caffeine intake) participated in a randomized, crossover, placebo-controlled and double-blind experiment. Each judoka performed three identical experimental sessions after: (a) ingestion of 3 mg/kg of caffeine (CAF-3); (b) ingestion of 6 mg/kg of caffeine (CAF-6); (c) ingestion of a placebo (PLAC). After 60 min for substance absorption, participants performed the following tests: (a) bench press exercise with 50% of the load representing one-repetition maximum (1RM), including three sets of three repetitions; (b) bench pull exercise with 50% of 1RM including three sets of three repetitions; (c) countermovement jump; (d) maximal isometric handgrip strength test; (e) dynamic and isometric versions of the Judogi Grip Strength Test. In comparison with PLAC, the ingestion of CAF-3 and CAF-6 increased peak bar velocity in the bench press exercise (1.27 ± 0.11 vs. 1.34 ± 0.13 and 1.34 ± 0.15 m/s, respectively; p < 0.01) and mean bar velocity in the bench pull exercise (1.03 ± 0.15 vs. 1.13 ± 0.13 and 1.17 ± 0.15 m/s; p < 0.05). Only CAF-6 increased mean bar velocity in the bench press exercise when compared with PLAC (0.96 ± 0.09 vs. 1.02 ± 0.11 m/s; p < 0.05). Both CAF-3 and CAF-6 significantly increased the number of repetitions in the Judogi Grip Strength Test (17 ± 10 vs. 20 ± 10 and 20 ± 10 repetitions; p < 0.05). There were no differences between PLAC and caffeine doses in the remaining tests. The pre-exercise ingestion of 3 and 6 mg/kg of caffeine effectively obtained meaningful improvements in several aspects associated with judo performance. From a practical viewpoint, the selection between 3 or 6 mg/kg of caffeine may depend on previously tested individual responses during simulated competition.

An international cross-sectional investigation on social media, fitspiration content exposure, and related risks during the COVID-19 self-isolation period.

With the global COVID-19 pandemic, governments from many countries in the world implemented various restrictions to prevent the SARS-Cov-2 virus's spread, including social distancing measures, quarantine, in-home lockdown, and the closure of services and public spaces. This led to an in-creased use of social media platforms to make people feel more connected, but also to maintain physical activity while self-isolating. Concerns about physical appearance and the desire to keep or reach a muscular and toned ideal body, might have further reinforced the engagement in fitness-related social media activities, like sharing progresses in training achievements or following more fitness contents on popular profiles. To better understand the underlying relation among these factors, the present study investigates 729 responses to the Exercise Addiction Inventory (EAI), the Appearance Anxiety Inventory (AAI), the Self-Compassion Scale (SCS) and their association to social media usage and compares the results cross-culturally in five countries (Spain, Lithuania, United Kingdom, Japan, and Hungary). Findings highlight significant differences between males and females, espe-cially in regard to the time spent online (U = 477.5, p = 0.036). Greater levels of appearance anxiety were associated with the exposure to fitness-related contents on social media. These results strongly confirm the previously highlighted association between fitspiration media and body image anxiety predominantly in females. Clinical implications and future considerations in terms of prevention and treatment in a situation of global emergency are also discussed.

Digital technology use and muscle-building behaviors in young adults.

OBJECTIVE: Digital technology use and muscle-building behaviors reflect a wide range of behaviors with associated health risks. However, links between digital technology use and muscle-building behaviors remain unknown and this study aimed to address this gap. METHOD: Data were collected from a diverse sample of 1,483 young adults (mean age 22.2 ± 2.0 years) participating in the population-based Eating and Activity over Time 2018 study. Gender-stratified-modified Poisson regression models were used to determine cross-sectional associations between three types of digital technology use (screen time, social media, weight-related self-monitoring apps) and five types of muscle-building behaviors (changing eating, exercise, protein powders/shakes, pre-workout drinks, steroids/growth hormone/creatine/amino acids) in young adulthood, adjusted for sociodemographic characteristics and body mass index. RESULTS: Screen time and social media were either not found to be associated with muscle-building behaviors or in a few instances, associated with less use of these behaviors (e.g., screen time and pre-workout drinks in men). In contrast, the use of weight-related self-monitoring apps was positively associated with all muscle-building behaviors, including steroids/growth hormone/creatine/amino acids in men (prevalence ratio [PR] = 1.83; 95% confidence interval [CI]: 1.13-2.97) and women (PR = 4.43; 95% CI: 1.68-11.68). DISCUSSION: While most recreational screen time may represent sedentary behaviors not related to muscle-building behaviors, weight-related self-monitoring apps are highly associated with more muscle-building behaviors and could be a future target for interventions to discourage the use of steroids and other harmful muscle-building substances.

Percepções e uso do metilfenidato entre universitários da área da Saúde em Ceilândia, DF, Brasil / Perceptions and use of methylphenidate among health students in Ceilândia, DF, Brazil / Percepciones y uso del metilfenidato entre universitarios del área de la salud en Ceilândia, Distrito Federal - DF, Brasil

As percepções e o uso de metilfenidato entre universitários foram investigados em estudo descritivo realizado em duas etapas. A primeira, quantitativa, foi realizada por meio do preenchimento de um questionário semiestruturado on-line. Para a segunda etapa, qualitativa, foi realizado um grupo focal. Dos 337 participantes da primeira etapa, 14,5% relataram usar o metilfenidato. Entre os usuários, a prevalência de uso sem prescrição foi maior para o sexo masculino (65,3%), após ingresso na faculdade (57,1%), e 61,2% relataram eventos adversos. O principal motivo de uso foi o doping intelectual (65,3%). Já na etapa qualitativa, além de reforçar os achados anteriores, foram identificados tópicos temáticos como a pressão externa exercida por familiares, sociedade e a rotina universitária. Esses achados apontam para a necessidade de medidas de apoio e orientação aos universitários e de reformulação do processo ensino-aprendizagem.(AU)

This descriptive study investigated the use and perceptions of methylphenidate among university students. The study was conducted in two stages. In the first stage (quantitative), the students completed an online semi-structured questionnaire. The second stage (qualitative) consisted of focus group discussions. Of the 337 participants in the first stage, 14.5% reported using methylphenidate. The prevalence of methylphenidate use without a prescription was greater among men (65.3%) and after starting university (57.1%); 61.2% of the students reported adverse events. The main reason for using the drug was intellectual doping (65.3%). In the qualitative stage, which reinforced the findings of the quantitative stage, we identified themes such as external pressure from family, society and university routine. The findings underline the need to provide student support and advice and reformulate the teaching and learning process.(AU)

Se investigaron las percepciones y el uso del metilfenidato entre universitarios, en un estudio descriptivo realizado en dos etapas. La primera, cuantitativa, se realizó por medio del llenado de un cuestionario semiestructurado online. Para la segunda etapa, cualitativa, se realizó un grupo focal. De los 337 participantes de la primera etapa, el 14,5% relató que usaba metilfenidato. Entre los usuarios, la prevalencia de uso sin prescripción fue mayor para el sexo masculino (65,3%), después del ingreso en la facultad (57,1%) y el 61,2% relataron eventos adversos. El principal motivo de uso fue el dopping intelectual (65,3%). En la etapa cualitativa, además de reforzar los hallazgos anteriores, se identificaron tópicos temáticos tales como la presión externa ejercida por los familiares, la sociedad y la rutina universitaria. Esos hallazgos señalan la necesidad de medidas de apoyo y orientación a los universitarios y de reformulación del proceso enseñanza-aprendizaje.(AU)

Substance use and meaning: transforming occupational participation and experience / Uso de substâncias e significados: transformando participação ocupacional e experiências

Abstract Introduction We draw on activity theory of concepts to examine 'meaning of occupation' and 'substance use' beyond preconceived notions of inherent positive or negative experiences. Objective To explore nuanced meanings of substance use and associated occupations. Method An online survey and semi-structured interviews were used to collect data from professionals about prevalence of substance use, substance effects, and personal experiences. In analyzing the interview data, we attended to substance use as a discrete occupation in itself, substance use co-occurring with other occupations, and substance use altering the performance, participation, and experience of occupations. Results Three broad themes related to meaning: i) complex meanings attributed to substance use, ii) meanings of substance use as shifting and variable, and iii) meanings of substance use in the context of other occupations. Substance use enhances occupations, transforms meaning of occupations, and mitigates less desired aspects of occupations. Work, construed as positively meaningful and valued in occupational therapy literature, was a source of stress, unhappiness, and worry; substance use facilitated relaxation and pleasure. Conclusion This study furthers occupational therapy knowledge with respect to implications for conceptualization that extend beyond dualist framings and implications for occupational therapy education, practice, and policy.

Resumo Introdução Foi utilizada a teoria da atividade de conceitos para examinar o "significado da ocupação" e o "uso de substâncias" para além das noções preconcebidas de experiências inerentes positivas ou negativas. Objetivo Explorar nuances do significado do uso de substâncias e as ocupações associadas. Método Uma pesquisa online e entrevistas semiestruturadas foram usadas para coletar dados de profissionais sobre a prevalência do uso de substâncias, efeitos de substâncias e experiências pessoais. Ao analisar os dados da entrevista, observamos que o uso de substâncias é uma ocupação discreta em si, ocorrendo com outras ocupações e o uso de substâncias altera o desempenho, a participação e a experiência das ocupações. Resultados Três grandes temas relacionados ao significado: i) significados complexos atribuídos ao uso de substâncias, ii) significados do uso de substâncias como mutante e variável, e iii) significados do uso de substâncias no contexto de outras ocupações. O uso de substâncias enlaça-se às ocupações, transforma os seus significados e mitiga aspectos menos desejados das ocupações. O trabalho, considerado positivamente significativo e valorizado na literatura da terapia ocupacional, era uma fonte de estresse, infelicidade e preocupação; o uso de substâncias facilitou o relaxamento e o prazer. Conclusão Este estudo aprofunda o conhecimento da terapia ocupacional com implicações para ampliar a conceptualização para além da fragmentação dualista e oferta implicações para a formação em terapia ocupacional, para a prática e a política.

Students' use of caffeine, alcohol, dietary supplements, and illegal substances for improving academic performance in a New Zealand university.

This study aimed to describe patterns of use and attitudes towards a broad variety of substances for improving academic performance at a New Zealand university. 685 students (from 1800 invited) completed an online questionnaire (38% response rate). They were asked about their lifetime and current substance use for improving academic performance, as well as their reasons for use, attitudes and perceptions of: caffeine, alcohol, dietary supplements, prescription stimulants, other prescription substances, and illicit substances. 80% (95% CI: 76.3, 82.5) reported ever using any substance to help improve academic performance, mainly to stay awake and improve concentration. Caffeine (70%, 95% CI: 66.3, 73.3) and dietary supplements (32%, 95% CI: 28.3, 35.5) were most commonly used. 4% (95% CI: 2.7, 5.9) reported use of prescription stimulants, mostly methylphenidate, and another 4% (95% CI: 2.7, 5.9) reported using illicit substances for improving academic performance. Users of prescription stimulants were more likely than non-users to believe that they were safe, morally acceptable, and that they should be available legally for enhancing academic performance. We close with discussions on broadening the focus of substances for improving academic performance in public health debates. Further qualitative research from small countries is also needed to move towards a place-based approach for clarifying ethical implications, inform policy in universities, and understand how injustices are created through the use of and ability to purchase different substances.

Exercise and Use of Enhancement Drugs at the Time of the COVID-19 Pandemic: A Multicultural Study on Coping Strategies During Self-Isolation and Related Risks.

Introduction: Little is known about the impact of restrictive measures during the COVID-19 pandemic on self-image and engagement in exercise and other coping strategies alongside the use of image and performance-enhancing drugs (IPEDs) to boost performance and appearance. Objectives: To assess the role of anxiety about appearance and self-compassion on the practice of physical exercise and use of IPEDs during lockdown. Methods: An international online questionnaire was carried out using the Exercise Addiction Inventory (EAI), the Appearance Anxiety Inventory (AAI), and the Self-Compassion Scale (SCS) in addition to questions on the use of IPEDs. Results: The sample consisted of 3,161 (65% female) adults from Italy (41.1%), Spain (15.7%), the United Kingdom (UK) (12.0%), Lithuania (11.6%), Portugal (10.5%), Japan (5.5%), and Hungary (3.5%). The mean age was 35.05 years (SD = 12.10). Overall, 4.3% of the participants were found to engage in excessive or problematic exercise with peaks registered in the UK (11.0%) and Spain (5.4%). The sample reported the use of a wide range of drugs and medicines to boost image and performance (28%) and maintained use during the lockdown, mostly in Hungary (56.6%), Japan (46.8%), and the UK (33.8%), with 6.4% who started to use a new drug. Significant appearance anxiety levels were found across the sample, with 18.1% in Italy, 16.9% in Japan, and 16.7% in Portugal. Logistic regression models revealed a strong association between physical exercise and IPED use. Anxiety about appearance also significantly increased the probability of using IPEDs. However, self-compassion did not significantly predict such behavior. Anxiety about appearance and self-compassion were non-significant predictors associated with engaging in physical exercise. Discussion and Conclusion: This study identified risks of problematic exercising and appearance anxiety among the general population during the COVID-19 lockdown period across all the participating countries with significant gender differences. Such behaviors were positively associated with the unsupervised use of IPEDs, although no interaction between physical exercise and appearance anxiety was observed. Further considerations are needed to explore the impact of socially restrictive measures among vulnerable groups, and the implementation of more targeted responses.

Athletes using ergogenic and medical sport supplements report more favourable attitudes to doping than non-users.

OBJECTIVES: Our study objectives were twofold: 1) examine whether users and non-users of different types of sport supplements vary in doping attitudes and sport supplement beliefs, and 2) determine whether the type of sport supplement is directly and indirectly (via sport supplement beliefs) related to doping attitudes. DESIGN: Cross-sectional survey. METHODS: Athletes (N=557; 77% male, mean±standard deviation; age=20.8±4.5 years, training=5.7±4.2h per week, competing=11.1±5.2 years) completed measures of sport supplement use, sport supplement beliefs, and doping attitudes. Sport supplements were classified into: ergogenic, medical, sport food and drinks, and superfoods. RESULTS: Compared to non-users, users of ergogenic (d=0.31, p<0.01) and medical (d=0.42, p<0.01) sport supplements reported more favourable attitudes towards doping. In addition, compared to non-users, users of ergogenic (d=1.10, p<0.01), medical (d=0.80, p<0.01) and sport food/drink (d=0.58, p<0.01) supplements reported stronger beliefs in the effectiveness of sport supplements to improve sport performance. Use of ergogenic, medical and sport food/drink supplements was indirectly related to doping attitudes via sport supplement beliefs. CONCLUSIONS: Researchers examining the relationship between sport supplement use and doping should differentiate between sport supplement types to improve measurement accuracy. Sport practitioners administering ergogenic and medical sport supplements to athletes may need to provide additional anti-doping education to counteract any favourable attitudes towards doping.