Effect of mixing two environmental stressors, pH and metal contaminants, on offspring of rats exposed during gestation and lactation.

In large urban centers, the toxicity of metal mixtures may be enhanced by physicochemical factors and environmental variables, including pH. Rio Grande, a municipality located in the extreme south of Brazil, has soils with high levels of contamination due to urban and industrial activities and a high prevalence of acid rain events. Previous studies have shown that contact with elutriate of these soils can cause physiological and reproductive changes. Thus, the objective of the present study was to evaluate, through animal experimentation, the effects of a metal-contaminated soil, acidified by hydrofluoric acid at two different pH values (5.2 and 3.6), on the health of offspring of rats exposed during gestation and lactation. Female Wistar rats were gavaged daily for 42 days (gestation and breastfeeding) with soil elutriate contaminated with metals, using solvent with different pH values (6.0, 5.2, and 3.6). The following parameters were evaluated in their offspring: body and organ weight, length, appearance of developmental characteristics, and swimming. Experimental groups in which the progenitors were exposed to the solution at pH 3.6 exhibited a delayed increase in weight as well as motor deficit, with a decreased weight (onset) and length (beginning and end), while exposure in association with soil was an aggravating factor for the damages to the body. Exposure to the solution at pH 5.2 decreased the initial weight of the animals, impaired some parameters of weight development, and caused motor deficit on the 14th day. These novel findings reveal that the exposure of progenitors to environmental stressors can compromise the health of the offspring. Special attention should be given to populations living in areas with high prevalence of acid rain.

Curvas de Crescimento de Bezerros da Raça Girolando / Growth curves of girolando calves / Curvas ce crecimiento de becerros de la raza girolando

O cruzamento de zebuíno com taurino busca associar a rusticidade com produtividade, melhorando a adaptação de um animal de alta produção ao meio ambiente. O presente trabalho avaliou o crescimento e desenvolvimento em 338 bezerros da raça Girolando à desmama. As médias observadas em machos e fêmeas foram, respectivamente, para peso ao nascer 31,88±5,22 kg e 29,57±4,2 kg, para o peso a desmama 133,9±29,9 kg e 136,6±29,4 kg, para o perímetro torácico ao nascimento 72,47±4,12 cm e 70,62±3,62 cm e para o perímetro torácico à desmama foram 119,3±8,96 cm e 118±7,93 cm. Os machos da raça Girolando nasceram mais pesados e com maior perímetro torácico que as fêmeas. O peso e o perímetro torácico não diferiram (p≥0,05) na desmama entre machos e fêmeas. No presente trabalho, os bezerros da raça Girolando apresentaram padrão de crescimento e desenvolvimento compatíveis para serem criados em condições comerciais de exploração leiteira.(AU)

The mix of Bos taurus and Bos indicus is a breeding alternative to improve animal production, associated to the adaptation of the productivity with environment resistance. The present research evaluated the growth and development in 338 Girolando calves from birth until weaning. The average weight observed in male and female was respectively, at birth 31.88±5.22 kg and 29.57±4.2 kg; and the weight at weaning was 133.9±29.9 kg and 136.6±29.4 kg; for the thorax perimeter at birth, was 72.47±4.12 cm and 70.62±3.62 cm; the thorax perimeter at weaning was 119.3±8.96 cm and 118±7.93 cm. Girolando male calves were heavier and had a larger thorax perimeter than female at birth. The weight and thorax perimeter didnt differ (p≥0.05) between males and females at weaning. In this study, Girolando calves presented satisfactory growth and development being able to be created in commercial conditions of milk explorations.(AU)

El cruce de los cebús con taurinos busca asociar el rústico con el productivo, mejorando la adaptación de un animal de alta producción al medio ambiente. La investigación evaluó el crecimiento y desarrollo de 338 becerros de la raza Girolando desde el nacimiento hasta el destete. Las medias observadas en machos y hembras, respectivamente, para el peso al nacer fueron 31,88±5,22 kg y 29,57±4,2 kg; para el peso al destete fueron 133,9±29,9 kg y 136,6±29,4 kg; para el perímetro torácico al nacimiento de 72,47±4,12 cm y 70,62±3,62 cm; perímetro del tórax al destete de 119,3±8,96 cm y 118±7,93 cm. El peso y el perímetro torácico no fueron diferentes (p≥0,05) al destete entre machos y hembras. En la actual investigación, los becerros de la raza Girolando presentaron padrón de crecimiento y desarrollo compatible para que sean criados en las condiciones comerciales de exploración lechera.(AU)

Curvas de Crescimento de Bezerros da Raça Girolando / Growth curves of girolando calves / Curvas ce crecimento de becerros de la raza girolando

O cruzamento de zebuíno com taurino busca associar a rusticidade com produtividade, melhorando a adaptação de um animal de alta produção ao meio ambiente. O presente trabalho avaliou o crescimento e desenvolvimento em 338 bezerros da raça Girolando à desmama. As médias observadas em machos e fêmeas foram, respectivamente, para peso ao nascer 31,88±5,22 kg e 29,57±4,2 kg, para o peso a desmama 133,9±29,9 kg e 136,6±29,4 kg, para o perímetro torácico ao nascimento 72,47±4,12 cm e 70,62±3,62 cm e para o perímetro torácico à desmama foram 119,3±8,96 cm e 118±7,93 cm. Os machos da raça Girolando nasceram mais pesados e com maior perímetro torácico que as fêmeas. O peso e o perímetro torácico não diferiram (p≥0,05) na desmama entre machos e fêmeas. No presente trabalho, os bezerros da raça Girolando apresentaram padrão de crescimento e desenvolvimento compatíveis para serem criados em condições comerciais de exploração leiteira.

The mix of Bos taurus and Bos indicus is a breeding alternative to improve animal production, associated to the adaptation of the productivity with environment resistance. The present research evaluated the growth and development in 338 Girolando calves from birth until weaning. The average weight observed in male and female was respectively, at birth 31.88±5.22 kg and 29.57±4.2 kg; and the weight at weaning was 133.9±29.9 kg and 136.6±29.4 kg; for the thorax perimeter at birth, was 72.47±4.12 cm and 70.62±3.62 cm; the thorax perimeter at weaning was 119.3±8.96 cm and 118±7.93 cm. Girolando male calves were heavier and had a larger thorax perimeter than female at birth. The weight and thorax perimeter didn’t differ (p≥0.05) between males and females at weaning. In this study, Girolando calves presented satisfactory growth and development being able to be created in commercial conditions of milk explorations.

El cruce de los cebús con taurinos busca asociar el rústico con el productivo, mejorando la adaptación de un animal de alta producción al medio ambiente. La investigación evaluó el crecimiento y desarrollo de 338 becerros de la raza Girolando desde el nacimiento hasta el destete. Las medias observadas en machos y hembras, respectivamente, para el peso al nacer fueron 31,88±5,22 kg y 29,57±4,2 kg; para el peso al destete fueron 133,9±29,9 kg y 136,6±29,4 kg; para el perímetro torácico al nacimiento de 72,47±4,12 cm y 70,62±3,62 cm; perímetro del tórax al destete de 119,3±8,96 cm y 118±7,93 cm. El peso y el perímetro torácico no fueron diferentes (p≥0,05) al destete entre machos y hembras. En la actual investigación, los becerros de la raza Girolando presentaron padrón de crecimiento y desarrollo compatible para que sean criados en las condiciones comerciales de exploración lechera.