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1.
Drug Test Anal ; 2024 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-38982650

RESUMO

An outline of the approach taken by international greyhound regulators to establish internationally harmonised screening limits and detection times in greyhound racing, which included a program of administration studies and an extensive and recognised risk assessment process, to ensure delivery of an effective anti-doping and medication control program.

2.
J Vet Pharmacol Ther ; 2024 Jun 16.
Artigo em Inglês | MEDLINE | ID: mdl-38880898

RESUMO

Clodronic acid is designated as a controlled medication for competition horses by the International Federation for Equestrian Sports and, according to the International Federation of Horseracing Authorities, clodronic acid is not to be administered to racehorses younger than 3.5 years or within 30 days prior to a race. In this study, 35 horses involved in competition were treated with a single dose of 1.53 mg clodronic acid/kg bodyweight intramuscularly. Plasma samples were obtained before treatment and 10, 20, 30, and 40 days post-administration. Clodronic acid concentrations were measured using a validated method, and the data were fitted using a nonlinear mixed effects model. The estimated depletion half-life of clodronic acid was 10.6 days (inter-individual variability: 17.9%). Age, body weight, sex, disease severity, dose, training days, training, and competition did not significantly impact the depletion half-life. The percentage of horses predicted via simulation to have clodronic acid concentrations below the assay's limit of quantification of 1.0 ng/mL was 93.9% at day 30 and 99.4% at Day 40. This study provides rationale to the equestrian federations and horse racing authorities to reliably establish a detection time for clodronic acid, assisting equine veterinarians in recommending a competition withdrawal time for the horses under their care.

3.
Sensors (Basel) ; 24(11)2024 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-38894073

RESUMO

This article presents a hierarchical control framework for autonomous vehicle trajectory planning and tracking, addressing the challenge of accurately following high-speed, at-limit maneuvers. The proposed time-optimal trajectory planning and tracking (TOTPT) framework utilizes a hierarchical control structure, with an offline trajectory optimization (TRO) module and an online nonlinear model predictive control (NMPC) module. The TRO layer generates minimum-lap-time trajectories using a direct collocation method, which optimizes the vehicle's path, velocity, and control inputs to achieve the fastest possible lap time, while respecting the vehicle dynamics and track constraints. The NMPC layer is responsible for precisely tracking the reference trajectories generated by the TRO in real time. The NMPC also incorporates a preview algorithm that utilizes the predicted future travel distance to estimate the optimal reference speed and curvature for the next time step, thereby improving the overall tracking performance. Simulation results on the Catalunya circuit demonstrated the framework's capability to accurately follow the time-optimal raceline at an average speed of 116 km/h, with a maximum lateral error of 0.32 m. The NMPC module uses an acados solver with a real-time iteration (RTI) scheme, to achieve a millisecond-level computation time, making it possible to implement it in real time in autonomous vehicles.

4.
Front Sports Act Living ; 6: 1415406, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38873227

RESUMO

In the dynamic sport of racecar driving, split-second decisions and rapid execution are imperative. Such an environment requires a tight functional coupling of perception and action. This paper introduces an approach for training racecar drivers rooted in ecological and embodied perspectives. It discusses three pivotal affordances of racecar driving: turn-ability, overtake-ability, and defend-ability. The paper also discusses the relevant environment and equipment (i.e., simulators) that can be useful for training racecar drivers. In addition, practice activities relevant for the actual racetrack or to the simulator are discussed. Coaches are encouraged to try and implement the proposed training strategies (or parts of it), evaluating their impact on racing performance. Furthermore, researchers can continue exploring these principles, fostering a fusion of empirical insights with practical expertise from coaches and racing communities. By synergizing empirical research with insights from practitioners, we can refine the strategies employed in the training of racecar drivers.

5.
Mol Biol Rep ; 51(1): 625, 2024 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-38717527

RESUMO

BACKGROUND: The currently known homing pigeon is a result of a sharp one-sided selection for flight characteristics focused on speed, endurance, and spatial orientation. This has led to extremely well-adapted athletic phenotypes in racing birds. METHODS: Here, we identify genes and pathways contributing to exercise adaptation in sport pigeons by applying next-generation transcriptome sequencing of m.pectoralis muscle samples, collected before and after a 300 km competition flight. RESULTS: The analysis of differentially expressed genes pictured the central role of pathways involved in fuel selection and muscle maintenance during flight, with a set of genes, in which variations may therefore be exploited for genetic improvement of the racing pigeon population towards specific categories of competition flights. CONCLUSIONS: The presented results are a background to understanding the genetic processes in the muscles of birds during flight and also are the starting point of further selection of genetic markers associated with racing performance in carrier pigeons.


Assuntos
Columbidae , Voo Animal , Transcriptoma , Animais , Columbidae/genética , Columbidae/fisiologia , Voo Animal/fisiologia , Transcriptoma/genética , Perfilação da Expressão Gênica/métodos , Músculos Peitorais/metabolismo , Músculos Peitorais/fisiologia , Músculo Esquelético/metabolismo , Músculo Esquelético/fisiologia
6.
J Anim Sci Technol ; 66(2): 425-437, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38628692

RESUMO

Exercise plays an important role in regulating energy homeostasis, which affects the diversity of the intestinal microbial community in humans and animals. To the best of the authors' knowledge, few studies have reported the associations between horse gut microbiota along with their predicted metabolic activities and the athletic ability of Jeju horses and Thoroughbreds living in Korea. This study was conducted to investigate the association between the gut microbiota and athletic performance in horses. This study sequenced the V3 and V4 hypervariable regions of the partial 16S rRNA genes obtained from racehorse fecal samples and compared the fecal microbiota between high- and low-performance Jeju horses and Thoroughbreds. Forty-nine fecal samples were divided into four groups: high-performance Jeju horses (HJ, n = 13), low-performance Jeju horses (LJ, n = 17), high-performance Thoroughbreds (HT, n = 9), and low-performance Thoroughbreds (LT, n = 10). The high-performance horse groups had a higher diversity of the bacterial community than the low-performance horse groups. Two common functional metabolic activities of the hindgut microbiota (i.e., tryptophan and succinate syntheses) were observed between the low-performance horse groups, indicating dysbiosis of gut microbiota and fatigue from exercise. On the other hand, high-performance horse groups showed enriched production of polyamines, butyrate, and vitamin K. The racing performance may be associated with the composition of the intestinal microbiota of Jeju horses and Thoroughbreds in Korea.

7.
BMC Psychiatry ; 24(1): 214, 2024 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-38504212

RESUMO

BACKGROUND: The Racing and Crowded Thoughts Questionnaire (RCTQ-13) is the most widely used specific scale for the measurement of racing thoughts, but there is currently no Spanish version that allow the evaluation in Spanish-speaking patients. The objective of this study is to translate, adapt, and validate the RCTQ-13 in a Colombian population with affective disorders. METHODS: The questionnaire was translated and back-translated, and corrections were implemented following a pilot test to improve comprehensibility. We included patients with Bipolar I Disorder and with Major depressive disorder seen in three centers in the city of Medellín, Colombia. We evaluate structural validity with confirmatory factor analysis, internal consistency, and test-retest reliability. Construct validity was also assessed with the comparison between euthymic, maniac, and depressive episodes and the correlation with worry, rumination, and mania scales. Responsiveness was measured 1 month after the first evaluation. Based on item response theory (IRT), we also estimated item difficulty, discrimination, and fit using a generalized partial credit model. RESULTS: Two hundred fifty subjects were included. Confirmatory factor analysis revealed that the three-factor structure of the scale was appropriate. Internal consistency was adequate for the entire scale (Cronbach's alpha = 0.95, 95% CI: 0.94-0.96) and for each factor. Test-retest reliability was good (intraclass correlation coefficient = 0.82, 95%IC: 0.70-0.88). For construct validity, we observed differences between patients with different types of affective episodes, a moderate positive correlation with the Penn State Worry Scale (r = 0.55) and the Ruminative Response Scale (r = 0.42), and a low negative correlation with the Young Mania Rating Scale (r = - 0.10). Responsiveness was proved to be adequate. Under IRT, the response thresholds for the response options are organized for all items. The infit was adequate for all items and the outfit was acceptable. CONCLUSIONS: The Spanish version of the RCTQ-13 is a reliable, valid, and responsive scale and can be used for the clinical assessment of the construct of racing and crowded thoughts in patients with the spectrum of affective disorders in whom this experience can be expressed with different nuances. Further research is needed to expand the relationship with rumination and worry.


Assuntos
Transtorno Depressivo Maior , Humanos , Psicometria , Reprodutibilidade dos Testes , Mania , Inquéritos e Questionários
8.
Animals (Basel) ; 14(5)2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38473189

RESUMO

Jumps racing is a form of Thoroughbred horse racing that involves hurdles and steeples and typically longer distances, and heavier weights compared with flat racing, which does not incorporate obstacles. In Australia, jumps racing is carried out only in Victoria, one of eight states and territories. The continuation of jumps racing is contentious due to the higher risk of fatalities, falls and injuries for horses, compared with flat racing. While measures have been introduced by the industry to improve the safety of riders and horses, the rates of fatalities, falls and injuries in horses participating in jumps races have not been collectively reported in Australia since the 2012 to 2014 race seasons. Although information on individual horse fatalities, falls and injuries is published by Racing Victoria in Stewards' Reports, the data are not aggregated, and so cannot readily be used to assess trends or evaluate the efficacy of safety measures introduced by the industry. The aim of this study was to determine the fatality, fall and injury rates for horses participating in hurdle and steeplechase races in Victoria in the 2022 and 2023 Thoroughbred horse jumps racing seasons compared with horses participating in flat races at the same race meets. Data on horse fatalities, falls and injuries were extracted from the published Racing Victoria race results and Stewards' Reports for the jumps races (n = 150) and corresponding flat races (n = 157) held at the 38 jumps race meets in Victoria in 2022 and 2023. Overall, horse fatalities, falls and injuries occurred at higher rates in jumps races compared with flat races during the study period. The rate of horse fatalities in jumps races was 3.3 per 1000 starts, with no fatalities in flat races. The rate of horse falls in hurdle races was 24 per 1000 starts and 41.6 per 1000 starts in steeplechase races, comparable with rates previously reported in the 2012 to 2014 seasons. There were no falls in flat races. Horse injuries occurred at a rate of 68.9 per 1000 starts in jumps races compared with 18.8 per 1000 starts in flat races. In hurdle and steeplechase races, veterinary clearance being required following horse injury was 5.4 times (OR 5.4, 95% CI 2.8-10.2) and 7.2 times (OR 7.2, 95% CI 3.3-15.6) more likely, respectively, compared with flat races. The risk of trauma was 4 times more likely in hurdle and steeplechase races (OR 4.8, 95% CI 1.7-13.3 and OR 4.1, 95% CI 1.2-13.4, respectively) and the risk of lameness was increased by 2.5 times in hurdles (OR 2.5, 95% CI 1.2-5.2) and 5.1 times in steeplechase races (OR 5.1, 95% CI 2.3-11.5), compared with flat races. These findings support concerns about the welfare of horses involved in jumps racing and of the need for further safety measures to reduce these risks.

9.
Int J Sports Physiol Perform ; 19(6): 545-549, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38531349

RESUMO

BACKGROUND: Durability (ie, the ability to attenuate the decline in performance after accumulated work) has been identified as a performance determinant in elite cyclists. The aim of the present study was to compare durability in elite cyclists of various performance levels, particularly after high-intensity work, referred to as "high-intensity durability." METHODS: Forty-nine (N = 49) male road cyclists were categorized as either under 23 years of age (U23) (N = 11), Pro Team (N = 13), or World Tour (N = 24). The participants' critical power (CP) was assessed during the preseason. Thereafter, the participants' maximum mean power (MMP) values were determined for efforts of different durations (from 5 s to 30 min) after different levels of accumulated work above CP (from 0 to 7.5 kJ·kg-1). RESULTS: U23 cyclists showed a significant reduction of all relative MMP values for durations ≥1 minute after ≥5 kJ·kg-1 above CP compared with the "fresh" state (0 kJ·kg-1), whereas in Pro Team and World Tour cyclists, a significant reduction was not observed until 7.5 kJ·kg-1 above CP. In the "fresh" state, both Pro Team and particularly World Tour cyclists attained higher MMP values for efforts ≥10 minutes than U23 riders. However, more differences emerged with greater previous work levels, and indeed after 7.5 kJ·kg-1 above CP World Tour cyclists attained higher MMP values than both U23 and Pro Team cyclists for most efforts (≥30 s). CONCLUSION: Pro Team and particularly World Tour cyclists tolerate greater levels of accumulated work at high intensity, which might support the importance of high-intensity durability for performance.


Assuntos
Desempenho Atlético , Ciclismo , Humanos , Ciclismo/fisiologia , Masculino , Desempenho Atlético/fisiologia , Adulto Jovem , Fatores de Tempo
10.
J Vet Res ; 68(1): 55-61, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38525231

RESUMO

Introduction: Although the presence of rotaviruses in pigeon samples has been reported since the 1980s, its importance as an aetiological agent of the "classical" young pigeon disease (YPD) was not proven until 2020, when the Henle-Koch postulates were confirmed for pigeon-type rotavirus A (RVA) genotype G18P(17). Material and Methods: From 2011 to 2020, archived liver samples from 117 pigeons submitted by 74 individual lofts were tested for the presence of pigeon-type RVA using a VP6-specific RT-qPCR test. For four positive racing pigeons, a more detailed necropsy and histopathological analysis was performed. Results: Indicators of an acute RVA infection were found in 24 out of 117 (20.5%) samples tested, the earliest in 2014. Necropsies of the four selected RVA-positive pigeons showed changes mainly in the liver, spleen and kidneys similar to those described by other researchers. The histopathological examination revealed mainly hyperaemia and necrosis in the liver, as well as mononuclear cell infiltrates in these organs. Conclusion: Pigeon-type RVA is also a cause of YPD in Poland and is a serious challenge for racing pigeon breeders and veterinarians, especially during the training and flights of young pigeons.

11.
Animals (Basel) ; 14(2)2024 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-38254375

RESUMO

The commercial greyhound racing industry in New Zealand is struggling with an eroding social license and 'on-notice' status. Multiple independent reviews of the industry have identified ongoing issues of animal welfare during and between races, euthanasia decisions, poor data tracking, a lack of transparency and problems with rehoming dogs, resulting in New Zealand animal advocacy agencies and the general public questioning the continuation of greyhound racing. The current paper assessed the New Zealand public's awareness and familiarity with commercial greyhound racing, identified current levels of public support or opposition for racing, and provided context in terms of engagement with greyhound racing using a comprehensive survey of a robust sample of New Zealanders. The results confirm that the social license of the greyhound industry is under challenge with most respondents expressing disagreement with or lack of knowledge of current industry practices and indicating they would vote in support of a ban. There is scope for increasing public acceptability by addressing welfare issues, increasing awareness of positive industry practices, and encouraging transparency of the greyhound racing agency. However, as greyhound racing is on the decline worldwide, calls are likely to continue for a phase-out of commercial greyhound racing.

12.
Scand J Med Sci Sports ; 34(1): e14533, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37955281

RESUMO

BACKGROUND: Our goal was to summarize and contextualize the available literature on alpine ski racing injury epidemiology, injury etiology, injury prevention measures, injury prevention context, and implementation issues. MATERIALS AND METHODS: We searched four electronic databases using predetermined search terms. We included original studies that assessed injury, injury risk factors, and injury mechanisms, and assessed and reported the effect of an injury prevention measure in alpine ski racing. Two authors independently conducted title-abstract screening, and one performed the full-text review. For data synthesis and categorization, we used the Translating Research into the Injury Prevention Practice framework and a modified and adapted version of the Haddon matrix. RESULTS: Of the 157 included studies, most corresponded to injury epidemiology and etiology, whereas few studies encompassed injury prevention measure development, implementation and evaluation. Preventive interventions targeting equipment, rules and regulations, course design and snow preparation were the most prevalent in the literature. Furthermore, various contextual factors in the current literature have been found, including gender, competition level, countries and federations, and time periods within a season. CONCLUSIONS: We provided an in-depth and comprehensive overview of the current state-of-the-art in the alpine ski racing context. We know a lot about little and little about a lot across all the areas associated with injury prevention in such context. The limitations in the literature yield a road map for designing future injury prevention studies to address the key gaps identified. A more comprehensive context-driven approach throughout all stages of injury prevention would benefit the ultimate implementation of effective preventive strategies.


Assuntos
Traumatismos em Atletas , Esqui , Humanos , Esqui/lesões , Fatores de Risco , Traumatismos em Atletas/prevenção & controle , Traumatismos em Atletas/epidemiologia
13.
Int J Sports Physiol Perform ; 19(1): 62-70, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-37922897

RESUMO

PURPOSE: This study determined the evolution of performance and pacing for each winner of the men's Olympic 1500-m running track final from 1924 to 2020. METHODS: Data were obtained from publicly available sources. When official splits were unavailable, times from sources such as YouTube were included and interpolated from video records. Final times, lap splits, and position in the peloton were included. The data are presented relative to 0 to 400 m, 400 to 800 m, 800 to 1200 m, and 1200 to 1500 m. Critical speed and D' were calculated using athletes' season's best times. RESULTS: Performance improved ∼25 seconds from 1924 to 2020, with most improvement (∼19 s) occurring in the first 10 finals. However, only 2 performances were world records, and only one runner won the event twice. Pacing evolved from a fast start-slow middle-fast finish pattern (reverse J-shaped) to a slower start with steady acceleration in the second half (J-shaped). The coefficient of variation for lap speeds ranged from 1.4% to 15.3%, consistent with a highly tactical pacing pattern. With few exceptions, the eventual winners were near the front throughout, although rarely in the leading position. There is evidence of a general increase in both critical speed and D' that parallels performance. CONCLUSIONS: An evolution in the pacing pattern occurred across several "eras" in the history of Olympic 1500-m racing, consistent with better trained athletes and improved technology. There has been a consistent tactical approach of following opponents until the latter stages, and athletes should develop tactical flexibility, related to their critical speed and D', in planning prerace strategy.


Assuntos
Desempenho Atlético , Corrida , Masculino , Humanos , Comportamento Competitivo , Atletas
14.
Front Physiol ; 14: 1227871, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38074336

RESUMO

Canoe slalom is an Olympic discipline where athletes race down a whitewater course in kayaks (K1) or canoes (C1) navigating a set of down-stream and up-stream gates. Kayak paddles are symmetrical and have a blade at each end, whereas C1 paddles have only one blade that must be moved across the boat to perform strokes on either the right or left side. Asymmetries in paddle force between the two sides of the boat may lead to a reduction in predicted race time. The purpose of this study was to quantify asymmetries in the paddle forces between the two sides for slalom paddling. Paddle forces for 42 canoe slalom athletes (C1 and K1) were quantified from the straight sections of a flat-water figure-of-eight course. Paddle forces were measured using strain gauges embedded in the paddle shaft, stroke type was identified using video, and boat trajectory was tracked using inertial measurement units and high-speed GPS: data were fused using in-house analysis software. Paddle forces were quantified by their peak force, and impulse during the stroke. Paddle forces for the kayakers had asymmetries of 14.2 to 17.1% for the male K1M and 11.1 to 14.4% for the women K1W. Canoeists were no more asymmetrical than the kayakers for their 'on-side' strokes between the right and left sides. However, there were considerable differences for their 'off-side' strokes: male C1M off-side paddle forces were similar to their 'on-side' forces for the same side, but the women C1W had a significantly lower (-20.8% to -29.5%) paddle forces for their 'off-side' strokes compared to their 'on-side' strokes on that same side. Despite an increasing number of younger male athletes being introduced to the switching technique, and it being used by C1M athletes in international competitions since 2014, C1M paddlers still do not use switching transitions as much as C1W. The data from this study indicate that there is a biomechanical reason for this sex-based difference in the higher proportion of off-side strokes used by the C1M athletes compared to C1W athletes: and this needs to be considered for optimal technique development and race performance.

15.
Animals (Basel) ; 13(21)2023 Oct 26.
Artigo em Inglês | MEDLINE | ID: mdl-37958092

RESUMO

Horseracing has identified several factors influencing staff wellbeing; however, the relationship between injury, anxiety, and depression is yet to be established. This study investigated anxiety and depression scores and their association to pain management, coping, and help-seeking behaviour in injured British horseracing staff. An online retrospective survey was completed by 175 participants, identifying injury prevalence, coping strategies, occupational risk factors, and Hospital Anxiety and Depression Scale (HADS) scores. Analysis identified 65.14% (n = 114) of staff reported anxiety scores above the threshold (≥8) and 59.52% (n = 104) of staff reported depression scores ≥8. Median anxiety and depression scores were higher for staff who viewed their employer as unhelpful (anxiety p = 0.001; depression p = 0.020). Heightened anxiety and depression were associated with an increased likelihood to use pain medication to manage at work, including non-steroidal anti-inflammatory drugs (NSAID's), alcohol, nicotine, and prescription drugs (p < 0.05). Implications for staff wellbeing is evident; anxiety and depression risks are high following injury, which may influence help-seeking behaviour, perceived job security, and coping mechanisms. This paper suggests it is vital to continue to investigate poor mental health and injury in racing staff and the implications for equine welfare.

16.
Front Vet Sci ; 10: 1260554, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37941814

RESUMO

Catastrophic musculoskeletal injuries (CMI) in horses are associated with both too little and too much high-speed exercise. In order to advise trainers on training and management strategies that minimize the risk of musculoskeletal injury (MSI), a better understanding of how training practices affect MSI in racehorses is needed. Data from prospective studies relating training data and MSI are complicated by the gradual development of pathology and the effect of this on the ability of horses to train consistently prior to the identification of an injury. To circumvent this, 66 Australian Thoroughbred trainers were surveyed on their intended training practices, including rest, pre-training, and race-fit practices. Associations between intended training practices and catastrophic and non-catastrophic race day MSI outcomes in two-year-old and mature (≥three-year-old) horses were assessed using multivariable negative binomial regression models. The incidence of two-year-old race day MSI was lower for trainers who preferred shorter times (weeks) to trial, less time in fast work pre-trial (p = 0.003), shorter, more frequent rest periods (p < 0.01) and higher amounts of fast work at 15.5-16.7 m/s once race-fit (p = 0.001). The incidence of mature horse race day MSI was lower for trainers who preferred longer rest periods (p = 0.026) and a high-volume pre-trial training strategy comprising a high volume of slower speed gallop training and longer times to trial compared to fast and light training programs (p = 0.004) for their mature horses, in addition to higher amounts of fast work at 15.5-16.7 m/s for their race-fit two-year-olds (p = 0.012). Race day CMI incidence was lower for trainers who preferred lower volumes of fast gallop work for their race-fit mature horses (p < 0.05). These results suggest that two-year-old training practices could affect MSI risk later in a horse's career, and that age and stage in training (pre-trial, race-fit) are important considerations when developing training practices to minimize the risk of MSI.

17.
J Parasitol ; 109(6): 543-549, 2023 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-37944598

RESUMO

An infestation of Ornithostrongylus quadriradiatus, has been found in a racing pigeon Columba livia domestica). In addition, this individual had a mild infection with Trichomonas spp. and Eimeria spp. The bird showed symptoms of increased appetite; unformed, dark- green feces; and lack of typical male behavior, but the general condition of this pigeon was good. The pigeon was euthanized because of a permanent inability to fly due to an injury to the wing. A postmortem examination revealed the presence of very small dark-pink twisted nematodes with the morphology of O. quadriradiatus in the small intestine, mainly the duodenum. Histopathology showed segmental inflammatory changes in the intestines caused by both blood-sucking nematodes and Eimeria spp. The 5.8S ribosomal ribonucleic acid polymerase chain reaction amplicons from deoxyribonucleic acid extracted from O. quadriradiatus had 82.40% identity with Australostrongylus victoriensis and 81.20% with Travassostrongylus spp. This is the first molecular characterization of O. quadriradiatus-a relatively rare pigeon parasite.


Assuntos
Doenças das Aves , Eimeria , Nematoides , Animais , Masculino , Columbidae/parasitologia , Doenças das Aves/parasitologia
18.
Antioxidants (Basel) ; 12(11)2023 Oct 28.
Artigo em Inglês | MEDLINE | ID: mdl-38001777

RESUMO

Green coffee extract is currently of great interest to researchers due to its high concentration of chlorogenic acid (CGA) and its potential health benefits. CGA constitutes 6 to 10% of the dry weight of the extract and, due to its anti-inflammatory properties, is a promising natural supplement and agent with therapeutic applications. The purpose of our study was to discover the effects of CGA on peripheral blood mononuclear cell proliferation, and the production of pro- and anti-inflammatory cytokines as well as reactive oxidative species (ROS) in horses during exercise. According to the findings, CGA can affect the proliferation of T helper cells. In addition, at a dose of 50 g/mL, CGA increased the activation of CD4+FoxP3+ and CD8+FoxP3+ regulatory cells. Physical activity decreases ROS production in CD5+ monocytes, but this effect depends on the concentration of CGA, and the effect of exercise on oxidative stress was lower in CD14+ than in CD5+ cells. Regardless of CGA content, CGA significantly increased the release of the anti-inflammatory cytokine IL-10. Moreover, the production of IL-17 was greater in cells treated with 50 g/mL of CGA from beginners compared to the control and advanced groups of horses. Our findings suggest that CGA may have immune-enhancing properties. This opens new avenues of research into the mechanisms of action of CGA and possible applications in prevention and health promotion in sport animals.

19.
J Quant Anal Sports ; 19(4): 273-293, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38020583

RESUMO

Successful performance in Formula One is determined by combination of both the driver's skill and race-car constructor advantage. This makes key performance questions in the sport difficult to answer. For example, who is the best Formula One driver, which is the best constructor, and what is their relative contribution to success? In this paper, we answer these questions based on data from the hybrid era in Formula One (2014-2021 seasons). We present a novel Bayesian multilevel rank-ordered logit regression method to model individual race finishing positions. We show that our modelling approach describes our data well, which allows for precise inferences about driver skill and constructor advantage. We conclude that Hamilton and Verstappen are the best drivers in the hybrid era, the top-three teams (Mercedes, Ferrari, and Red Bull) clearly outperform other constructors, and approximately 88 % of the variance in race results is explained by the constructor. We argue that this modelling approach may prove useful for sports beyond Formula One, as it creates performance ratings for independent components contributing to success.

20.
Vet J ; 300-302: 106040, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37898456

RESUMO

Arrhythmias are commonly reported in exercising horses, however due to regulatory constraints electrocardiograms (ECGs) are acquired during training but not competition, raising questions about the repeatability of findings. The aims were (1) compare training and competition arrhythmias and (2) describe the repeatability of arrhythmias during maximal-intensity exercise. A convenience sample of 52 healthy Thoroughbreds (aged 8.7 ± 2.5 years) competing in the World Professional Chuckwagon Association were obtained, totaling 152 training or competition ECGs (2-7 ECGs/horse). Speed, heart rate (HR) and arrhythmias (supraventricular premature complex, SVPC; ventricular premature complex, VPC) were examined. Pre- and post-recovery (approximately 6 min) blood samples measured lactate and high-sensitivity troponin-T. Training and competition arrythmias were compared (Friedman's test) and reliability of repeated ECGs assessed (intraclass correlation; P < 0.05). Training vs. competition: Forty horses had clean tracing from training and competition (n = 80 ECGs); the number and type of arrhythmias were not different. In training, VPCs were present in 7/40 horses (median [interquartile range, IQR]/ECG; range; 0 [0,0]; 0-4) and 9/40 horses (0 [0,0]; 0-5) in active-recovery. In competition, VPCs were present in 7/40 horses (0 [0,0]; 0-8) and 8/40 horses (0 [0,0]; 0-5) in active-recovery. Arrhythmias were primarily single premature complexes. Training and competition speed, HR, lactate and troponin-T did not differ however, sampling was too early for peak serum Troponin-T levels. Repeatability: total arrhythmias between serial ECGs did not differ. The reliability to detect SVPCs and VPCs was poor to moderate, and poor, respectively. Overall, the total number of arrhythmias was repeatable, but the reliability of arrhythmia type was poor to moderate.


Assuntos
Doenças dos Cavalos , Condicionamento Físico Animal , Complexos Ventriculares Prematuros , Cavalos , Animais , Troponina T , Reprodutibilidade dos Testes , Doenças dos Cavalos/diagnóstico , Complexos Ventriculares Prematuros/diagnóstico , Complexos Ventriculares Prematuros/veterinária , Condicionamento Físico Animal/fisiologia , Lactatos
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