Digital panoramic radiography as a tool for analyzing the quality of trabecular bone microarchitecture / Radiografia panorâmica digital como ferramenta de análise da qualidade da microarquitetura óssea trabecular

Abstract Introduction Osteoporosis is a metabolic disease characterized by reduced bone mineral density, often accompanied by loss of quality of trabecular bone microarchitecture. Objective To assess the quality or degradation of trabecular bone microarchitecture in digital panoramic radiography to better predict the risk of fragility fractures. Material and method The sample included 68 female patients, age-matched, and divided into three groups according to densitometric results. Trabecular Bone Score values were measured and digital panoramic radiographs were taken. Fractal analysis with box counting was conducted in the region of premolars and angle of the mandible, with regions of interest measuring 64×64 and 80×120 pixels. In the statistical analysis, Pearson's correlation was applied between the Trabecular Bone Score and fractal analysis results obtained in each group, using age as a control variable and assigning individualized age ranges within groups. Result A moderate correlation was identified in the regions of interest of 64×64 and 80×120 pixels at the angle of the mandible in the osteoporosis group and in the normal group. A moderate correlation was also obtained using age as a control variable in the 64x64 pixel regions of interest in the premolar region. Considering age range, the within-group analysis presented a strong correlation in the osteoporosis group and moderate correlation in the osteopenia and normal groups. Conclusion Fractal analysis in digital panoramic radiographs was shown to be a promising predictive instrument of bone microarchitecture quality.

Resumo Introdução A osteoporose é uma doença metabólica caracterizada pela redução da densidade mineral óssea, muitas vezes acompanhada da perda de qualidade da microarquitetura óssea trabecular. Objetivo Avaliar a qualidade da microarquitetura óssea trabecular em radiografia panorâmica digital a fim de identificar precocemente a sua degradação, possibilitando melhor predição do risco de fraturas por fragilidade. Material e método A amostra consistiu de 68 pacientes do sexo feminino, pareadas por idade, e divididas em 3 grupos conforme resultado densitométrico. Foram aferidos os valores de Trabecular Bone Score e realizadas radiografias panorâmicas digitais. A análise fractal com box counting foi feita na região de pré-molares e ângulo da mandíbula, com regiões de interesse medindo 64x64 e 80x120 pixels. Na análise estatística utilizou-se a correlação de Pearson entre os resultados de Trabecular Bone Score e de análise fractal obtidos em cada grupo, utilizando-se a idade como variável de controle e através de atribuição de grupos etários individualizados intragrupos. Resultado Identificou-se correlação moderada nas regiões de interesse de 64x64 e 80x120 pixels, em ângulo da mandíbula no grupo Osteoporose e no grupo normal. Também se obteve correlação moderada utilizando a idade como variável de controle nas regiões de interesse de 64x64 pixels, em região de pré-molares. A análise intragrupos, considerando a faixa etária, resultou em correlação forte, no grupo osteoporose e moderada nos grupos osteopenia e normal. Conclusão A análise fractal em radiografias panorâmicas digitais se mostrou promissora como instrumento preditivo da qualidade de microarquitetura óssea.

Prevalence and morphometric analysis of double mental foramen and double mandibular foramen from digital panoramic radiographs / Prevalencia y análisis morfométrico de foramen mental y foramen mandibular dobles a través de radiografías panorámicas digitales

The morphological variations of the mental foramen (MF) and mandibular foramen (MBF) have been studied for several years, and the prevalence and morphometric characteristics of double and triple foramina have been reported. The objective of this study was to establish the prevalence of variations in the MF and MBF, and to carry out a morphometric analysis of a Chilean population using digital panoramic radiographs. The study included 927 radiographs; the observed prevalence of double MF was 2.58 %, while the prevalence of double MBF was 1.51 %. No cases of triple foramina were found. In men, double MF was found more frequently in the left hemiarch (64.28 % of cases), while in women it was more frequent in the right hemiarch (80 %). Double MBF was found more frequently in the right hemiarch in women (80 % of cases), while the distribution between left and right in men was even. The mean area, width and height of the double MF were 5.46 mm2, 2.77 mm and 2.57 mm respectively. The means of the same morphometric measurements in double MBF were 6.37 mm2, 2.27 mm and 3.19 mm respectively. In both foramina, statistically significant differences were only found between the height of the foramen and the age of the subjects, with the observation that the greater the subject's age, the smaller the height. Dental surgeons must take these anatomical variants into consideration in clinical and surgical actions; timely diagnosis by radiograph is important to avoid possible complications.

Las variaciones morfológicas del foramen mental (FM) y mandibular (FMB) han sido estudiadas durante varios años, reportándose su prevalencia y las características morfométricas de forámenes dobles y triples. El objetivo de este estudio fue establecer la prevalencia de variaciones de los FM y FMB y realizar un análisis morfométrico a través de radiografías panorámicas digitales de una muestra de población chilena. En el estudio se incluyeron 927 radiografías y se observó una prevalencia de FM doble de 2,58 %, mientras que la prevalencia de FMB doble fue de 1,51 %. No se encontraron casos de forámenes triples. En hombres, el FM doble se encontró mayoritariamente en la hemiarcada izquierda (64,28 % de los casos), mientras que en mujeres fue en la hemiarcada derecha (80% de los casos). Para el caso de los FMB dobles, en mujeres se presentó mayoritariamente en la hemiarcada derecha (80 % de los casos), mientras que en hombres fue equitativo en ambos lados. El promedio del área, ancho y alto de los FM dobles fue de 5,46 mm2, 2,77 mm y 2,57 mm, respectivamente. Asimismo, los promedios de estas medidas morfométricas para el FMB doble fueron 6,37 mm2, 2,27 mm y 3,19 mm, respectivamente. Para ambos forámenes sólo se encontraron diferencias estadísticamente significativas entre el alto y la edad de los sujetos, observando que, a mayor edad menor era el alto del foramen. Los cirujanos dentistas deben tener en consideración estas variantes anatómicas para la realización de distintas acciones clínicas y quirúrgicas, su diagnóstico radiográfico oportuno es importante para prevenir posibles complicaciones.

Índices de simetría condilar y mandibular a través de radiografías panorámicas digitales en una muestra de pacientes chilenos / Condylar and mandibular symmetry indexes through digital panoramic radiographs in a sample of Chileans patients

La simetría mandibular puede alterarse por diversos motivos. Variados estudios buscan definir parámetros de "normalidad" y para ello se han descrito técnicas que utilizan la radiografía panorámica (RPN). El objetivo de este estudio fue determinar índices de simetría mandibular/condilar en una muestra de pacientes chilenos. Se realizó un estudio descriptivo de corte trasversal en RPN digitales obtenidas de la Clínica Odontológica de la Universidad de La Frontera. Se aplicaron criterios de inclusión: pacientes mayores de 18 años, dentición permanente completa hasta el primer molar; y de exclusión: signos radiográficos de alteraciones óseas y/ o cirugía mandibular, cóndilos no visibles, ortodoncia. Se utilizó el software ImageJ para dibujar rectas y medir la altura de la rama y cóndilo mandibular del lado derecho e izquierdo de acuerdo a la técnica propuesta por Kjellberg et al. (1994). Con estas medidas se calculó el índice de simetría entre altura condilar y rama (S1); y entre altura condilar y mandibular (S2). 235 RPN digitales fueron analizadas (95 hombres; 140 mujeres) con edad promedio de 24,98±7,32 años. El promedio de S1 fue de 93,74 % (±3,85) en hombres y 93,41 % (±5,77) en mujeres, mientras que para S2 fue de 90,50 % (±6,51) en hombres y 90,27 % (±7,80) en mujeres, sin diferencias significativas para ninguno de ambos índices (p=0,347 y p=0,233, respectivamente). En cuanto a la edad, tampoco se encontraron diferencias significativas en el promedio de los índices S1 y S2 para cada rango etario (p=0,594 y p=0,669, respectivamente). Mediante este estudio se concluye que hay un alto porcentaje de pacientes con simetría mandibular/condilar en ambos sexos y en diferentes rangos etarios, esto sin considerar el estado de salud o presencia de alteraciones morfológicas y/o funcionales.

Mandibular symmetry may be modified by various conditions. A number of studies have attempted to define parameters of "normality" and several techniques have been described using digital orthopantomography (OPG). The aim of this study was to determine mandibular/condylar symmetry indexes in a sample of Chilean patients. A cross sectional descriptive study in digital OPG obtained from the Dental Clinic of Universidad de La Frontera was performed. Inclusion criteria applied were: Patients older than 18 years, complete permanent dentition up to the first molar. Exclusion criteria were also applied: Radiographic signs of bone disease and/or mandibular surgery, not visible condyles, orthodontics. ImageJ software was used to draw lines and measure the height of the ramus and mandibular condyle on the right and left side with the technique postulated by Kjellberg (1994). With these measurements, the symmetry index between condylar height and ramus (S1) and between condylar and mandibular height (S2) were calculated. The study analyzed 235 digital OPG (95 men, 140 women) with an average age of 24.98 ± 7.32 years. The S1 average was 93.74 % (± 3.85) for men and 93.41 % (± 5.77) for women, and for S2 it was 90.50 % (± 6.51) for men and 90.27 % (± 7.80) for women, without significant differences for either index (p=0.347 and p=0.233, respectively). No significant differences were found in reference to age, for indexes S1 and S2 (p=0.594 and p=0.669, respectively). Therefore, it is concluded that there is presence of condylar/mandibular symmetry in both sexes and in age ranges, when measuring digital OPGs without considering health status or presence of any morphological or functional alteration.