RESUMO
Introducción: La colangitis biliar primaria es una enfermedad hepática colestásica. La historia natural y el pronóstico de esta enfermedad ha sido difícil de caracterizar. En el área de Latinoamérica y el Caribe son muy escasos los trabajos que investigan el tema. Objetivo: Describir las características clínicas, evolutivas, y supervivencia en pacientes con colangitis biliar primaria. Material y Métodos: Estudio descriptivo, longitudinal y ambispectivo de pacientes mayores de 18 años, con diagnóstico de CBP, atendidos en el Instituto de Gastroenterología entre septiembre de 2003 y enero de 2020; se evaluaron variables demográficas, clínicas, bioquímicas e histológicas a partir de los registros de historias clínicas. Para el procesamiento de los datos se utilizó el paquete estadístico SPSS versión 21.0. Resultados: Se incluyeron 45 pacientes, la mayoría del sexo femenino (95 %) y con forma de presentación sintomática (55,6 %). El 71,1 % de los pacientes presentó alguna complicación, siendo la cirrosis la más frecuente, en 28,8 % de los cirróticos hubo complicaciones secundarias a la lesión hepática predominando la ascitis, seguido del sangrado digestivo variceal, la encefalopatía, el carcinoma hepatocelular (CHC) y las infecciones bacterianas asociadas a la cirrosis. La supervivencia acumulativa superó 95 % a los cinco años. Conclusiones: La supervivencia de los pacientes con CBP fue elevada en el tiempo a pesar del elevado índice de complicaciones.
Introduction: Primary biliary cholangitis (PBC) is a cholestatic liver disease. The natural history and prognosis of PBC has been difficult to characterize. In Latin America and the Caribbean, there are very few research works on the subject. Objective: To describe the clinical and developmental characteristics and survival of patients with PBC. Material and Methods: Descriptive, longitudinal and ambispective study of patients older than 18 years with a diagnosis of PBC, treated at the Institute of Gastroenterology between September 2003 and January 2020. Demographic, clinical, biochemical and histological variables were evaluated from the data of medical records. For data processing, the statistical package SPSS version 21,0 was used. Results: A total of 45 patients were included, most of them female (95 %) and with symptomatic presentation (55,6 %). In addition, 71,1 % of the patients presented some complications, cirrhosis being the most frequent; in 28,8 % of the cirrhotic patients, there were complications secondary to liver injury, predominantly ascites, followed by variceal digestive bleeding, encephalopathy, hepatocellular carcinoma (HCC), and bacterial infections associated with cirrhosis. Cumulative survival exceeded 95 % at five years. Conclusions: The survival of patients with PBC was high over time despite the high rate of complications.
Assuntos
Humanos , Masculino , FemininoRESUMO
OBJECTIVE: To analyze the application of concept nursing of accelerated rehabilitation surgery in orthopedic postoperative recovery. METHODS: A total of 120 patients who received orthopedic surgery were divided into the control group undergoing routine orthopedic nursing and the observation group undergoing the concept of accelerated rehabilitation surgery nursing. RESULTS: Patients in the observation group had shorter in-bed activity time and out-of-bed activity time, average time of hospital stay, and lower total treatment costs. The incidence of incision infection, respiratory system infection, digestive tract infection, urinary tract infection, deep vein thrombosis, and other complications in the observation group was much lower. The recovery scores of joint function in the observation group at 1, 3, 6, and 12 months after the operation were all better, and the recovery rate of joint function within 1 year after the operation was higher. CONCLUSION: Following the concept of accelerated rehabilitation surgery nursing during the perioperative period can improve the quality of postoperative orthopedic recovery.
