Proteomic Profiling of Muscular Adaptations to Short-Term Concentric Versus Eccentric Exercise Training in Humans.

The molecular mechanisms underlying muscular adaptations to concentric (CON) and eccentric (ECC) exercise training have been extensively explored. However, most previous studies have focused on specifically selected proteins, thus, unable to provide a comprehensive protein profile and potentially missing the crucial mechanisms underlying muscular adaptation to exercise training. We herein aimed to investigate proteomic profiles of human skeletal muscle in response to short-term resistance training. Twenty young males were randomly and evenly assigned to two groups to complete a 4-week either ECC or CON training program. Measurements of body composition and physiological function of the quadriceps femoris were conducted both before and after the training. Muscle biopsies from the vastus lateralis of randomly selected participants (five in ECC and four in CON) of both before and after the training were analyzed using the liquid-chromatography tandem mass spectrometry in combination with bioinformatics analysis. Neither group presented a significant difference in body composition or leg muscle mass; however, muscle peak torque, total work, and maximal voluntary contraction were significantly increased after the training in both groups. Proteomics analysis revealed 122 differentially abundant proteins (DAPs; p value < 0.05 & fold change >1.5 or <0.67) in ECC, of which the increased DAPs were mainly related to skeletal muscle contraction and cytoskeleton and enriched specifically in the pentose phosphate pathway, extracellular matrix-receptor interaction, and PI3K-Akt signaling pathway, whereas the decreased DAPs were associated with the mitochondrial respiratory chain. One hundred one DAPs were identified in CON, of which the increased DAPs were primarily involved in translation/protein synthesis and the mitochondria respiratory, whereas the decreased DAPs were related to metabolic processes, cytoskeleton, and de-ubiquitination. In conclusion, the 4-week CON and ECC training resulted in distinctly different proteomic profiles, especially in proteins related to muscular structure and metabolism.

Developing a global medicine student pre- and post-travel curriculum.

BACKGROUND: The popularity of short-term global health experiences amongst US medical students has been increasing. However, it remains a challenge for medical schools to comprehensively prepare students to work in an international environment and to contribute in ethically responsible and meaningful ways. Students of the Global Medicine program (GMED) of the UIC College of Medicine Center for Global Health set out to develop a pre-and-post travel curriculum that addresses some of these challenges. METHODS: The students surveyed the literature of 66 published global health curricula and identified aspects of pre-and-post travel training that were found to be under-addressed. They then developed a curriculum in conjunction with GMED faculty that incorporated these identified aspects of pre-and-post travel training. RESULTS: Five aspects of pre-and-post travel training were identified as being under-addressed in the literature while traveling. These domains include: [1] examining power relations associated with neo-colonization between and within countries; [2] training for bi-directional learning; [3] examining motivations and goals for participating in global health; [4] addressing personal resiliency and psychosocial wellbeing related to students' travel, and; [5] reflecting on the challenging aspects of the fieldwork experience. CONCLUSIONS: The student-driven curriculum is being integrated into the GMED program through structured didactic sessions, one-on-one mentor meetings and small group discussions. Once students have traveled, the curriculum will be evaluated with the foreign partners they visited.

Short-term training helps second-language learners read like native readers: An ERP study.

This randomized controlled trial study aimed to examine what experience other than immersion may help adult learners read with native-like neural responses. We compared a group of 13 native Chinese English learners completing English letter-sound association training with another group of 12 completing visual symbol-sound association training and included one group of native English readers as the reference. The results showed that after three hours of training, all learners no longer showed attenuated cross-modal mismatch negativity (MMN) to English letter-sound integration as in the pretest. After six hours of training, the learners receiving English letter-sound association training showed enhanced cross-modal MMN and theta oscillations, as native English readers did. The enhanced neural responses were significantly correlated with better phonological awareness. Thus, with training specific to critical second language reading skills of appropriate dosages, adult learners can overcome the constraints of their native language background and learn to read with native-like neural responses.

Changhai advanced endoscopy courses for ERCP (CHANCE) training program: A short-term training model in China.

BACKGROUND: There is huge shortage of ERCP practitioners (ERCPists) in China, and ERCP training is urgently needed. ChangHai Advanced eNdoscopy Courses for ERCP (CHANCE) is a 4-month program for ERCP training since 2004. This study evaluated the efficiency of this short-term training model, and reported on the ERCP careers of the trainees following completion of the CHANCE program. METHODS: This study was a retrospective investigation included all the CHANCE trainees from Jan 2004 to Dec 2014. Questionnaires were sent to all trainees. The career competence percentage, ERCP careers and predictive factors of career competence were investigated and analyzed. RESULTS: A total of 413 trainees participated in the CHANCE program over 11 years covered by the survey and 258 questionnaires were valid for the study. The mean (SD) age of the trainees was 35.36 (4.17), and the male to female ratio was 4.4:1. The average follow-up time was 7.77 (3.44) years. A total of 173 (67.1%) trainees had achieved career competence. In terms of ERCP careers, the mean annual ERCP volume was 120.60 (96.67), with a complication percentage of 8.2%. Hospital qualification, compliance with follow-up learning guidance, participating academic activity, and practitioner type were identified predictive factors of career competence. CONCLUSIONS: As a short-term training program, the CHANCE achieved an acceptable career competence percentage, providing endoscopists more chances to learn ERCP and giving them appropriate training guidance for career competence. This training mode is worth promoting in developing countries with shortage of ERCPists.

Motor Performance and Skill Acquisition in Oral Motor Training With Exergames: A Pilot Study.

Objective: To investigate the effects of oral-motor training with exergames on motor performance and motor skill acquisition in two different age groups. Methods: Thirty-two healthy participants were recruited in the current pilot study and divided equally into two groups (Gen Z and Baby Boomers) according to their age. A pair of electromyographic (EMG) electrodes were placed on the participants' masseter muscles. The EMG device communicated via Bluetooth with a mobile video game in response to the electromyographic activity of the masseter muscles during clenching. During the experimental session, participants were asked to play a video game in five blocks of 5 min each, with a 3-min break between each time block. The goal of the game was to collect as many coins (game points) as possible and to dodge/avoid upcoming obstacles (game life). Motor performance was assessed by performance scores and the number of game lives. Skill acquisition was measured by task efficiency (ratio of performance scores and number of game lives) across time blocks. Results: The results of the study showed significantly lower performance scores (p < 0.001), a higher number of game lives (p < 0.001), and lower task efficiency in the Baby Boomer group compared to the Gen Z group. Specifically, the results showed that there was a significant difference in task efficiency between the first and second, third and fourth, fourth- and fifth-time blocks in the Gen Z group (p < 0.002). However, there was only a significant difference between first- and second-time blocks in the Baby Boomer group (p = 1.012), suggesting that skill acquisition in the Baby Boomer group did not change significantly over the course of the time blocks. Conclusion: The study showed higher motor performance and superior motor skill acquisition with novel exergame training in the Gen Z group compared to the Baby Boomer group. The results of the study indicate that there is an improvement in oral motor skills with short-term training, yet the differences in oral motor skills between the two groups are still evident. The Baby Boomer group, unlike the Gen Z group, did not show robust improvement in task efficiency over the course of the series.

Exploring spatial ability in healthcare students and the relationship to training with virtual and actual objects.

INTRODUCTION: The relationship between the spatial ability levels of students and anatomy education is not well established in the literature, but it was stated that students should take short-term training during the first years of their education. There is limited number of studies on this topic. In that respect, the aim of this study was to determine the spatial ability levels of medical, dental and nursing students and to evaluate whether this ability level showed difference with respect to faculty, anatomy courses attended or short-term training, or not. MATERIALS AND METHODS: Study sample was composed of 1071 students. Data were collected by Personal Information Form, Visualization of Views Test (VoVT) and Cross Section Test (CST). Data analyses were done by SPSS 21 package software. RESULTS: Students were determined to have medium level spatial ability. Medical and dental students were found to have higher spatial ability levels than nursing students. Medical and nursing students' CST scores showed significant difference after taking anatomy course. After short-term training, both CST and VoVT scores of students differed significantly. CONCLUSION: Supporting anatomy courses with education materials appropriate for the spatial ability level of students and introducing spatial ability development trainings in small groups would aid in increasing spatial ability levels of students.

Application of short-term training path for prenatal ultrasound diagnostician in primary hospitals / 中华医学教育探索杂志

Objective:To explore the establishment and effect of short-term training path for prenatal ultrasound diagnosticians in primary hospitals.Methods:A total of 105 trainees from in total 5 batches of the "prenatal ultrasound screening training base" in Chongqing were selected as the research objects, and a combination of multiple teaching methods was used to carry out specialized training for primary prenatal ultrasound screening doctors before and after training. Theoretical examinations and practical operation assessments were performed, and after training, remote image quality control and continuous improvement methods were established for trainees to assess training effectiveness. SPSS 21.0 was used for t test, Wilcoxon test and chi-square test. Results:After training, the results of the theoretical examinations and practical operation examinations of the trainees were higher than those before the training ( P<0.05), and after the completion of the training, the number of trainees who returned to their original units to carry out prenatal ultrasound examination, the average number of prenatal ultrasound examinations per month and the number of referrals to higher prenatal diagnosis centers of each trainee increased significantly ( P<0.05). Conclusion:The establishment of short-term training path for prenatal ultrasound diagnosis can effectively improve the professional theoretical knowledge and practical operation level of prenatal ultrasound doctors in primary hospitals, and greatly solve the problem of technical promotion under the shortage of grassroots hospitals.

Changes in EEG Brain Connectivity Caused by Short-Term BCI Neurofeedback-Rehabilitation Training: A Case Study.

BACKGROUND: In combined with neurofeedback, Motor Imagery (MI) based Brain-Computer Interface (BCI) has been an effective long-term treatment therapy for motor dysfunction caused by neurological injury in the brain (e.g., post-stroke hemiplegia). However, individual neurological differences have led to variability in the single sessions of rehabilitation training. Research on the impact of short training sessions on brain functioning patterns can help evaluate and standardize the short duration of rehabilitation training. In this paper, we use the electroencephalogram (EEG) signals to explore the brain patterns' changes after a short-term rehabilitation training. MATERIALS AND METHODS: Using an EEG-BCI system, we analyzed the changes in short-term (about 1-h) MI training data with and without visual feedback, respectively. We first examined the EEG signal's Mu band power's attenuation caused by Event-Related Desynchronization (ERD). Then we use the EEG's Event-Related Potentials (ERP) features to construct brain networks and evaluate the training from multiple perspectives: small-scale based on single nodes, medium-scale based on hemispheres, and large-scale based on all-brain. RESULTS: Results showed no significant difference in the ERD power attenuation estimation in both groups. But the neurofeedback group's ERP brain network parameters had substantial changes and trend properties compared to the group without feedback. The neurofeedback group's Mu band power's attenuation increased but not significantly (fitting line slope = 0.2, t-test value p > 0.05) after the short-term MI training, while the non-feedback group occurred an insignificant decrease (fitting line slope = -0.4, t-test value p > 0.05). In the ERP-based brain network analysis, the neurofeedback group's network parameters were attenuated in all scales significantly (t-test value: p < 0.01); while the non-feedback group's most network parameters didn't change significantly (t-test value: p > 0.05). CONCLUSION: The MI-BCI training's short-term effects does not show up in the ERD analysis significantly but can be detected by ERP-based network analysis significantly. Results inspire the efficient evaluation of short-term rehabilitation training and provide a useful reference for subsequent studies.

The Effect of Short-Term Wingate-Based High Intensity Interval Training on Anaerobic Power and Isokinetic Muscle Function in Adolescent Badminton Players.

Badminton requires both aerobic fitness and anaerobic ability for high performance. High intensity interval training (HIIT) is a traditional training method for improving fitness. In this study, we investigated whether short-term Wingate-based HIIT is effective for improving anaerobic activity in youth badminton players. Participants included 32 total badminton players in middle school and high school. They were divided into two groups (HIIT and moderate continuous training (MCT)). Training occurred for 4 weeks in total, three times a week, for 30 min each session. A body composition test, isokinetic knee muscle function test (60°/s, 240°/s), Wingate anaerobic power test (30 s × 5 sets), and analysis of heart rate changes were undertaken before and after training. After 4 weeks, body fat decreased in the HIIT group (p = 0.019); they also showed superior anaerobic ability compared to the MCT group. Differences were statistically significant in 3-4 sets (three sets, p = 0.019; four sets, p = 0.021). Regarding fatigue, the HIIT group showed superior fatigue improvement after training and better fatigue recovery ability in 3~5 sets (three sets, p = 0.032; four sets, p = 0.017; five sets, p = 0.003) than the MCT group. Neither group exhibited changes in heart rate during the anaerobic power test after training. Both groups improved in terms of isokinetic knee muscle function at 60°/s with no differences. However, at 240°/s, the HIIT group showed a statistically significant improvement (p = 0.035). Therefore, HIIT for 4 weeks improved the athletes' performance and physical strength.

The integrative role of the M1 in motor sequence learning.

The primary motor cortex (M1) is crucial in motor learning. Whether the M1 encodes the motor engram for sequential finger tapping formed by an emphasis on speed is still inconclusive. The active states of engrams are hard to discriminate from the motor execution per se. As preparatory activity reflects the upcoming movement parameters, we hypothesized that the retrieval of motor engrams generated by different learning modes is reflected as a learning-related increase in the preparatory activity of the M1. To test this hypothesis, we evaluated the preparatory activity during the learning of sequential finger-tapping with the non-dominant left hand using a 7T functional MRI. Participants alternated between performing a tapping sequence as quickly as possible (maximum mode) or at a constant speed of 2 Hz paced by a sequence-specifying visual cue (constant mode). We found a training-related increase in preparatory activity in the network covering the bilateral anterior intraparietal sulcus and inferior parietal lobule extending to the right M1 during the maximum mode and the right M1 during the constant mode. These findings indicate that the M1, as the last effector of the motor output, integrates the motor engram distributed through the networks despite training mode differences.

High- and moderate-intensity training modify LPS-induced ex-vivo interleukin-10 production in obese men in response to an acute exercise bout.

The aim of this study was to evaluate the inflammatory (peripheral and lipopolysaccharide (LPS)-stimulated released from whole blood) and metabolic (glucose and insulin) profile of inactive obese men in response to two isoenergetic models of aerobic exercise training (~300  kcal each exercise session). Twenty-two participants (28.7 ± 1.6 years; BMI = 34.4 ± 0.1 kg/m2) were randomized into two groups: I) HIIT: high-intensity interval training (10× 1 bout: 1 min - 100% Maximal Aerobic Velocity) or II) MICT: moderate-intensity continuous training (65% Maximal Aerobic Velocity; kcal equal to HIIT). Both groups trained three times per week for 6-weeks. Fasting blood samples were collected before and 0, 30, and 60 min after exercise during the first and last training sessions for evaluation of: I) MIP-1ɑ, insulin, glucose, visceral and subcutaneous fat depots, oral glucose tolerance test, and homeostatic model assessment of insulin resistance (HOMA-IR) index; II) Peripheral (TNF-α, IL-6, and IL-10) and LPS-stimulated release of TNF-α and IL-10 were analyzed before, 0, and 60 min after sessions. IL-6 concentration remained elevated up to 60-min after the acute exercise session (p < 0.001), and IL-10 concentration was higher after 30 and 60-min (p = 0.001) compared to rest, independent of training period and protocol. AUC of IL-10 presented effect of type of training (p = 0.023) with MICT group showed significantly higher values than the HIIT. The ex-vivo assay showed higher IL-10 secretion in response to LPS immediately (p = 0.003) after both acute MICT and HIIT exercise sessions, independent of training period. Fifteen subjects presented decreased HOMA-IR after 6-weeks and seven presented an increase in this index. When we excluded the two least responsive subjects, it was possible to observe a decrease in HOMA-IR (p = 0.020) after training. Taken together, our results suggest that both HIIT and MICT (with same energy expenditure) promote similar effects on HOMA-IR and led to elevations in IL-10 production in LPS-stimulated whole blood, suggesting that leukocytes had an enhanced ability to secrete anti-inflammatory cytokines after the exercise bout.

The motor engram as a dynamic change of the cortical network during early sequence learning: An fMRI study.

Neural substrates of motor engrams in the human brain are hard to identify because their dormant states are difficult to discriminate. We utilized eigenvector centrality (EC) to measure the network information that accumulates as an engram during learning. To discriminate engrams formed by emphasis on speed or accuracy, we conducted functional MRI on 58 normal volunteers as they performed a sequential finger-tapping task with the non-dominant left hand. Participants alternated between performing a tapping sequence as quickly as possible (maximum mode) or at a constant speed of 2 Hz, paced by a sequence-specifying visual cue (constant mode). We depicted the formation of the motor engram by characterizing the dormant state as the increase in EC of the resting epoch throughout the training course, and the ecphory, or activated state, as the increment in EC during the task epoch relative to the alternated resting epoch. We found that a network covering the left anterior intraparietal sulcus and inferior parietal lobule represented the engram for the speed of execution, whereas bilateral premotor cortex and right primary motor cortex represented the sequential order of movements. This constitutes the first demonstration of learning-mode specific motor engrams formed by only 30 min of training.

A Comparison of the Effectiveness Between Three Different Endoscopic Surgical Skill Training Programs for Medical Students Using the Infant Laparoscopic Fundoplication Simulator: A Randomized Controlled Trial.

Background and Aim: Training programs for developing laparoscopic suturing skills range from dry-box training to virtual simulator training. There are advantages and disadvantages to each training method; however, which training is best for medical students and young surgeons is unclear. The aim of this study was to compare the proficiency of medical students in acquiring laparoscopic suturing skills after various routes of short-term training: via a video, an expert teacher, or a virtual simulator. Materials and Methods: Seventeen medical students were registered and divided randomly into three groups: group receiving personal training while watching a training video (video group), group receiving training under the guidance of an expert (teaching group), and group receiving personal training with a virtual simulator (virtual group). The students practiced laparoscopic suturing and tying skills for 1 hour. Following their training, they performed the evaluation task of three sutures and ties using a laparoscopic fundoplication simulator. We developed a 1-year-old infant body model (body weight 10 kg) based on computed tomography data and established a pneumoperitoneum body model based on a clinical situation. Results: The path length of the assistant forceps in the virtual group tended to be longer than in the other groups. The average acceleration of the assistant forceps in the virtual group was faster than in the other groups (P = .04). There were no significant differences in the other evaluation parameters. Conclusion: A long-term and combination training study should be performed to develop the best method for training medical students and inexperienced young surgeons.

Behavioral learning and skill acquisition during a natural yet novel biting task.

OBJECTIVE: To investigate the effect of short-term training on behavioral learning and skill acquisition during a natural yet novel biting task. METHODS: Thirty (18 women) healthy volunteers in the age range of 18-32 years were divided into a naive (n = 17) and expert (n = 13) groups based on the self-reported familiarity to perform a complex behavioral biting task. The volunteers participated in a single experimental session divided into three sets with three series, each with ten trials of a standardized biting task. The task was to position, split and retrieve a sunflower seed from its shell without crushing the seed. The two consecutive sets were separated by fifteen minutes of short-term training. During the short-term training, the participants repeatedly performed the biting task for about fifteen minutes. A five-point grading system was devised to determine the performance and video registrations were made to determine the duration of the task. RESULTS: There was a significant main effect of training on the task performance scores (P < .001). The performance scores of the naive group before training was significantly lower than all the sets of the expert group (P < .010). The performance scores of the naive group were also significantly better after training than before (P = .001). However, the expert group took significantly shorter time to complete the task than the naive group. CONCLUSION: The results of the present study show a significant effect of training on the performance of a complex behavioral biting task. Training resulted in improved performance scores and a subtle decrease in the duration of the task.

Are you ready? A systematic review of pre-departure resources for global health electives.

BACKGROUND: There has been an exponential increase in the offering of short-term international field experiences in recent years in response to student demands for global health opportunities. Pre-departure preparation is an essential component to equip trainees with the adequate safety, wellness, and cultural competence needed to engage in a meaningful and mutually beneficial elective. This review seeks to quantify the plethora of pre-departure preparation training available to public health, clinical, and undergraduate trainees across the continuum of education for short-term experiences in low-and middle-income countries (LMICs). METHODS: We performed a systematic review of Pubmed, Embase, Web of Science, Scopus, and Ovid Global Health in February, 2018. A three-concept search was employed and included "global or international health"; "education or preparation of personnel/students"; and "field programs or travel." The study teamed used PRISMA reporting guidelines to conduct title and full-text reviews and conduct data extraction and analysis. RESULTS: The search returned 2506 unique articles. Of these, 55 met inclusion criteria and were included in the final review. Ninety one percent (91%) of articles focused on pre-departure trainings for medical students and residents. Nine thematic domains for short-term international field experiences emerged; culture, safety, and project-specific knowledge were the most frequently covered domains while mentorship, professionalism, and emotional wellness and culture shock were least common. Approximately half (53.3%) of studies specifically evaluated the pre-departure component of the international experience using a survey or evaluation form. Recommendations emerged from these evaluations including early engagement with international partners, inclusion of self-reflection exercises and site-specific content, and utilization of interactive approaches in learning. Some institutions face barriers to conducting pre-departure preparation such as lack of dedicated faculty, finances, and institutional support. CONCLUSIONS: Interest in pre-departure training for international experiences is growing but few programs conduct and publish evaluations of these trainings. Pre-departure trainings should be developed in partnership with receiving institutions and faculty and incorporate critical self- reflection throughout the experience. In addition to the experience itself, institutions need to evaluate these curricula to better understand how they influence trainees' capacity to effectively engage in LMIC settings.

Practice and reflection of short-term orthopedics training in primary hospitals / 中华医学教育探索杂志

In order to provide more practicable and convenient continuing medical education for orthopedic surgeons in primary hospitals and expand the academic influence of expert lecturers and host hospitals in the region, our department hosted nine short-term training courses of orthopedic surgery jointly with primary hospitals, which lasted for 1 to 1.5 days on weekends from June 2001 to October 2017, with expert lectures as the main form. Traumatic orthopedics was the main topic, and most expert lecturers were orthopedic experts from famous hospitals within the province and the whole country, as well as the experts from the host hospital. More than 1200 orthopedic and surgical physicians in local districts and counties participated in the training, and excellent social effect has been achieved. For short-term orthopedic training jointly held with hospitals in prefecture-level cities, the topic of training should be carefully selected, and duration of the training and number of lecturers should be controlled, so as to achieve satisfactory social effects under the premise of low cost of administrative resources.

Pocket-size ultrasound device in cholelithiasis: diagnostic accuracy and efficacy of short-term training.

Pocket-size ultrasound devices (PSUD) are now widely available becoming a useful tool for diagnostic and therapeutic purposes. We aim to investigate the accuracy of PSUD in diagnosing cholelithiasis as compared to traditional ultrasonography. Moreover, we tested the reliability of PSUD when performed by inexperienced internal medicine residents after a short-term training. We consecutively enrolled inpatients and outpatients referred to undergo abdominal ultrasonography for signs or symptoms of gallbladder diseases in two different hospitals. Every patient underwent two independent examinations with PSUD by both expert (EXPPSUD) and nonexpert operators (N-EXPPSUD), and a conventional examination with traditional abdominal ultrasound (AUS). Every naive operator underwent a short-term training with a 2-h theoretical lesson, and a practical training focused on gallbladder under expert operator supervision. Overall, 146 patients were consecutively enrolled. Considering conventional AUS as the reference standard, sensitivity and specificity of EXPPSUD were, respectively, 93.75 and 100%. Sensitivity and specificity of N-EXPPSUD were, respectively, 75 and 91.25%. Nevertheless, when considering outpatients, PSUD has a high diagnostic accuracy even when performed by N-EXPPSUD with sensitivity of 93% and specificity of 88%. PSUD is a reliable tool for the diagnosis of cholelithiasis when used by expert operators potentially reducing the need for further diagnostic tests. It can even be successfully used by non-expert operators in outpatients setting after a short focussed training.

Internet Search Alters Intra- and Inter-regional Synchronization in the Temporal Gyrus.

Internet search changed the way we store and recall information and possibly altered our brain functions. Previous studies suggested that Internet search facilitates the information-acquisition process. However, this process may cause individuals to lose the ability to store and recollect specific contents. Despite the numerous behavioral studies conducted in this field, little is known about the neural mechanisms underlying Internet searches. The present study explores potential brain activity changes induced by Internet search. The whole paradigm includes three phases, namely, pre-resting state fMRI (rs-fMRI) scan, 6-day Internet search training, and post rs-fMRI scan. We detected the functional integrations induced by Internet search training by comparing post- with pre-scan. Regional homogeneity (ReHo) and functional connectivity (FC) were used to detect intra- and interregional synchronized activity in 42 university students. Compared with pre-scan, post-scan showed decreased ReHo in the temporal gyrus, the middle frontal gyrus, and the postcentral gyrus. Further seed-based FC analysis showed that the temporal gyrus exhibited decreased FC in the parahippocampal cortex and the temporal gyrus after training. Based on the features of current task and functions exhibited by these brain regions, results indicate that short-term Internet search training changed the brain regional activities involved in memory retrieval. In general, this study provides evidence that supports the idea that Internet search can affect our brain functions.

[Effect of short-term global health training on tropical diseases and its related factors].

OBJECTIVE: To investigate the effect of short-term global health training on tropical diseases in China, so as to provide the reference in professional trainings. METHODS: The study took the short-term global health training project on tropical diseases in China as an example. The structured questionnaires were distributed to each trainee pre- and post-training course. RESULTS: A total of 89 trainees were included in the survey, and 68.5% (61 cases) of the trainees were older than 35 years and 85.4% (76 cases) of the trainees came from provincial institutes. The passing rate for the test of global health knowledge was significantly improved from the pre-training test (18.0%, 16/89) to the post one (68.2%, 58/85) (χ2 = 44.930, P < 0.05) . The knowledge of global health was closely related to the professionals' capacity, i.e., the education level, age, professional title, and experience of international cooperation, but was not statistically related to their genders. CONCLUSIONS: This kind of short-term trainings not only greatly improves the professionals' knowledge of tropical diseases control, but also is expected to play a leading role in the international cooperation of global health and tropical diseases control in the future.

Effect of short-term global health training on tropical diseases and its relat-ed factors / 中国血吸虫病防治杂志

Objective To investigate the effect of short-term global health training on tropical diseases in China,so as to provide the reference in professional trainings.Methods The study took the short-term global health training project on tropical diseases in China as an example.The structured questionnaires were distributed to each trainee pre-and post-training course. Results A total of 89 trainees were included in the survey,and 68.5%(61 cases)of the trainees were older than 35 years and 85.4%(76 cases)of the trainees came from provincial institutes.The passing rate for the test of global health knowledge was sig-nificantly improved from the pre-training test(18.0%,16/89)to the post one(68.2%,58/85)(χ2=44.930,P<0.05).The knowledge of global health was closely related to the professionals'capacity,i.e.,the education level,age,professional title, and experience of international cooperation,but was not statistically related to their genders. Conclusion This kind of short-term trainings not only greatly improves the professionals'knowledge of tropical diseases control,but also is expected to play a leading role in the international cooperation of global health and tropical diseases control in the future.