RESUMO
Background: The gold standard for osseointegration remains the autogenous bone graft, but biomaterials such as Beta - tricalcium phosphate (ß - TCP) in its pure-phase showed promising results to be practical bone substitutes. This kind of implants are optimal candidates for bone integration due to their osseoconductive, biocompatibility, bioactivity, and absorptive properties. Methods: A systematic review was conducted using 5 databases (Cochrane Library, PubMed, Scielo, Medline-Bireme and Google Scholar) for searching published studies between January 1st 2011 and June 15th 2021. Only clinical and experimental studies, and case reports were included in this research. Human and animal studies published only in Portuguese or English with clinical, radiologic, and histologic evidence of new bone formation, osseoconduction, and osseointegration were included. This systematic review was reported according to PRISMA guidelines. Results: Approximately 14.554 articles were initially found, but after advanced searching using specific including and excluding keywords, matching Boolean operators "AND," "OR" and "NOT," and after excluding duplicates, a total of 12 articles were included for this systematic review, including experimental works, a retrospective study, a randomized controlled clinical study, a randomized prospective study, a prospective observational study, and a case report. All articles showed 100% effectiveness in bone integration after ß - TCP implantation by clinical, image and/or histologic assessment. Implant shape and porosity seem to have influence in osseointegration process. ß - TCP can give predictable, sustainable, and adequate new bone formation with the least infection rates in implant placement cases and patient morbidity, which is the current goals for bone integration, augmentation and replacement. Conclusion: ß - TCP in its pure-phase is widely used in dentistry and maxillofacial surgery, but there is a lack of information about the use of this biomaterial for filling critical segmental defects of long bones in veterinary medicine. In this area, only experimental studies in small defects were carried out, with no clinical cases performed in animals with a longer observation time. ß - TCP can produce predictable, sustainable, and adequate bone formation, with minimal infection rates and low patient morbidity. But more clinical studies in the future, demonstrating specific metric measurements in relation to bone consolidation, as well as showing results using other shapes of this implant are needed to evaluate further in depth osseoconductive and osseointegrative characteristics of this biomaterial, in order to develop new comparisons and quantitative analyses for its use in veterinary medicine as a bone replacement.
RESUMO
Os fibrossarcomas de tecido mole surgem de tecidos mesodérmicos e podem partir dos tecidos fibroso, muscular, adiposo e sinovial. Sua etiologia permanece desconhecida, mas é comumente associado à vacinação. O objetivo deste trabalho é relatar a remoção cirúrgica de um fibrossarcoma torácico felino, com envolvimento de costelas e diafragma. Para perfeita reparação na parede torácica, se fez neces¬sário a utilização de malha de polipropileno, permitido o restabelecimento da dinâmica respiratória do paciente. Quinze meses após o procedimento cirúrgico, o animal não apresentou qualquer sinal de recidiva
The soft tissue fibrosarcomas arise from mesodermal tissues may come from fibrous tissue, muscle, fat and synovial fluid. Its etiology remains unknown, but may be associated with vaccination. The aim of this study is to report the surgical removal of the thoracic fibrosarcoma in a feline, with involvement of the ribs and diaphragm. For perfect repair of the chest wall, it was necessary the use of polypro¬pylene mesh, allowed the restoration of respiratory dynamics of the patient. Fifteen months after surgery, the animal did not show any sign of recurrence, contrary to the literature
Assuntos
Animais , Gatos , Fibromatose Abdominal , Gatos , Parede Abdominal , Parede Torácica , Toracoplastia/veterináriaRESUMO
Os fibrossarcomas de tecido mole surgem de tecidos mesodérmicos e podem partir dos tecidos fibroso, muscular, adiposo e sinovial. Sua etiologia permanece desconhecida, mas é comumente associado à vacinação. O objetivo deste trabalho é relatar a remoção cirúrgica de um fibrossarcoma torácico felino, com envolvimento de costelas e diafragma. Para perfeita reparação na parede torácica, se fez neces¬sário a utilização de malha de polipropileno, permitido o restabelecimento da dinâmica respiratória do paciente. Quinze meses após o procedimento cirúrgico, o animal não apresentou qualquer sinal de recidiva(AU)
The soft tissue fibrosarcomas arise from mesodermal tissues may come from fibrous tissue, muscle, fat and synovial fluid. Its etiology remains unknown, but may be associated with vaccination. The aim of this study is to report the surgical removal of the thoracic fibrosarcoma in a feline, with involvement of the ribs and diaphragm. For perfect repair of the chest wall, it was necessary the use of polypro¬pylene mesh, allowed the restoration of respiratory dynamics of the patient. Fifteen months after surgery, the animal did not show any sign of recurrence, contrary to the literature(AU)