Community violence in neighborhoods and common mental disorders among Brazilian adolescents.

BACKGROUND: This study aims to explore the association between exposure to neighborhood violence and the presence of common mental disorders (CMDs) among Brazilian adolescents aged 12 to 17 years. Additionally, we aim to analyze whether sex, age and race are modifiers of the effect of this association. METHODS: The study comprised 1,686 adolescents residing in the municipality of Rio de Janeiro, situated in the Southeast region of Brazil. To measure exposure to community violence, we constructed three crime indicators using data from Civil Police of the State of Rio de Janeiro: crimes against property, nonlethal crimes, and lethal crimes. Employing geospatial analysis based on the adolescents' residence location, logistic regression modeling was performed to measure the association between violence and CMDs. RESULTS: Adolescents living in regions with higher rates of the three types of violence studied herein were more likely to have CMDs, with odds ratios (ORs) ranging from 2.33 to 2.99. When stratified by sex, age and race, girls, older adolescents and blacks have a greater magnitude of effect on the measure of association, indicating a heightened risk for CMDs. CONCLUSION: This study provides important contributions to the public health field, as it reveals new information on the influence of community violence on the mental health of adolescents. Given the elevated rates of violence globally, knowing the effects of such violence on adolescents becomes crucial for the prevention and treatment of CMDs within this population.

Glosario básico actualizado de términos odontológicos de periodoncia y ortodoncia, inglés-español / Updated basic glossary of periodontal and orthodontic dental terms, English-Spanish / Glossário básico atualizado de termos dentários em periodontologia e ortodontia, inglês-espanhol

RESUMEN Los grandes volúmenes de información científica que se generan a diario demandan del profesional de la salud una actualización constante. La mayoría de esa información proviene de países de habla inglesa o se publica en ese idioma; de ahí la imperante necesidad por parte del profesional de aprender dicho idioma para poder apropiarse y/o divulgar en lo posible toda esa creación científica. En ese contexto, los glosarios de términos de diferentes idiomas aportan a cubrir esa necesidad. El presente glosario está concebido como instrumento de búsqueda rápida y actual de términos en inglés relacionados con la ortodoncia y la periodoncia. Recopila más de 150 vocablos de dichas especialidades, y está dirigido tanto a estudiantes como profesionales que deseen consultar eficazmente el significado de palabras propias de dichas ramas. En el presente glosario, no se pretende exponer todos los vocablos y frases pertenecientes a las mismas, pues eso sería imposible. Cabe aclarar que se excluyeron los términos cuya escritura se asemeje al español, excepto aquellos que su significado no sea el mismo.

ABSTRACT The large volumes of scientific information generated daily require health professionals to be constantly updated. Most of this information comes from English-speaking countries or is published in that language; hence, the professional must learn that language to be able to appropriate and/or disseminate as much as possible all this scientific creation. In this context, glossaries of terms from different languages contribute to cover this need. This glossary is conceived as a quick and up-to-date search tool for English terms related to orthodontics and periodontics. It compiles more than 150 terms from these specialties and is intended for students and professionals who wish to consult the meaning of words specific to these fields efficiently. It is not intended to present all the words and phrases pertaining to these specialties, as that would be impossible. It should be clarified that terms with spelling similar to Spanish were excluded, except those whose meaning is not the same.

RESUMO Os grandes volumes de informação científica gerados diariamente exigem dos profissionais de saúde uma atualização constante. A maior parte desta informação provém de países anglófonos ou é publicada nessa língua; daí a necessidade imperiosa de o profissional aprender essa língua para poder apropriar-se e/ou difundir, na medida do possível, toda esta criação científica. Neste contexto, os glossários de termos de diferentes línguas ajudam a responder a esta necessidade. Este glossário foi concebido como uma ferramenta de pesquisa rápida e atualizada de termos ingleses relacionados com a ortodontia e a periodontia. Reúne mais de 150 termos destas especialidades e destina-se tanto a estudantes como a profissionais que pretendam consultar eficazmente o significado de palavras específicas destes domínios. Não se pretende apresentar todas as palavras e expressões pertencentes a estas especialidades, pois tal seria impossível. Convém esclarecer que foram excluídos os termos cuja grafia é semelhante à do espanhol, exceto aqueles cujo significado não é o mesmo.

Nutritional status in perianal Crohn's disease: are we underestimating the impact?

Symptomatic perianal disease is common in patients with Crohn's disease (CD), and perianal fistulas represent the primary form of anal involvement. This type of involvement is associated with a poor prognosis and a disabling course. The treatment is challenging and involves both surgical and medical approaches. Despite combined therapy, a significant portion of patients may still require proctectomy to control the symptoms. Consequently, investigating factors that may influence the outcome of perianal disease remains a priority area of research in CD. Nutritional deficiencies are well documented among CD patients with luminal forms of involvement and are closely related to poor clinical outcomes, therapy response, and postoperative complications. As a result, leading guidelines recommend regular nutritional assessment and correction of nutritional deficiencies in patients requiring a surgical approach. Despite these recommendations and the high rate of surgeries among CD patients with perianal disease, there is a shortage of studies addressing the real impact of nutritional status on the course and outcomes of perianal disease. This knowledge gap underscores the importance of further research to understand better and improve the management of perianal CD. This narrative review aims to provide an overview of nutritional status assessment and the influence of nutritional status on the outcomes of patients with perianal CD.

An Overview of Robotic Colorectal Surgery Adoption and Training in Brazil.

Background and Objectives: Robotic surgical systems have rapidly become integrated into colorectal surgery practice in recent years, particularly for rectal resections, where the advantages of robotic platforms over conventional laparoscopy are more pronounced. However, as with any technological advancement, the initial high costs can be a limiting factor, leading to unequal health service access, especially in middle- and lower-income countries. Materials and Method: A narrative review was conducted with the objective of providing an overview of the escalating adoption, current training programmes, and certification process of robotic colorectal surgery in Brazil. Results: Brazil has witnessed a rapid increase in robotic platforms in recent years. Currently, there are 106 robotic systems installed nationwide. However, approximately 60% of the medical facilities which adopted robotic platforms are in the Southeast region, which is both the most populous and economically prosperous in the country. The Brazilian Society of Coloproctology recently established clear rules for the training programme and certification of colorectal surgeons in robotic surgery. The key components of the training encompass theoretical content, virtual robotic simulation, observation, assistance, and supervised procedures in colorectal surgery. Although the training parameters are well established, no colorectal surgery residency programme in Brazil has yet integrated the teaching and training of robotic surgery into its curriculum. Thus far, the training process has been led by private institutions and the industry. Conclusion: Despite the fast spread of robotic platforms across Brazil, several challenges still need to be addressed to democratise training and promote the widespread use of these platforms. It is crucial to tackle these obstacles to achieve greater integration of robotic technology in colorectal surgery throughout the country.

Validación del modelo multidimensional de perfeccionismo en población infantil / Validation of the multidimensional perfectionism model with a child population

(analítico) El modelo multidimensional del perfeccionismo ha sido estudiado exiguamente en población infantil debido a la falta de instrumentos que evalúen simultáneamente las tres dimensiones del constructo: autorientado, socialmente prescrito y orientado a otros. En países hispanohablantes solo recientemente ha sido posible operacionalizar estos aspectos, por lo cual se propuso comprobar la bondad de ajuste del modelo tridimensional, integrando factorialmente dos escalas de perfeccionismo infantil. Participaron 2249 menores completando las escalas de perfeccionismo autorientado y de perfeccionismo social, y medidas de arrogancia y depresión. Se observó un ajuste válido y confiable del modelo de tres factores, que incluyó parcelas y covariancias entre residuos. La validez se evidenció, además, mediante correlaciones positivas del perfeccionismo con la arrogancia y la depresión. Los hallazgos demuestran que el modelo multidimensional puede ser generalizable a población infantil.

(analytical) The multidimensional perfectionism model has had a limited application with children due to the lack of instruments that simultaneously assess the three dimensions of this construct: self-oriented, socially prescribed and other-oriented. In Spanish-speaking countries, it has only recently been possible to operationalize these aspects. This study tested the fit of the three-dimensional model by factorially integrating two child perfectionism scales. A total of 2249 children participated in the study, completing the Self-Oriented Perfectionism and Social Perfectionism scales, as well as measures of Arrogance and Depression. A valid and reliable fit for the three-factor model that included parcels and covariances between residuals was observed. Validity was further evidenced by positive correlations of perfectionism with arrogance and depression. These results demonstrate that the multidimensional model can be generalized to be applied with a child population.

(analítico) O modelo multidimensional do perfeccionismo tem sido pouco estudado em crianças devido à falta de instrumentos que avaliem simultaneamente as três dimensões do construto: autodirigido, socialmente prescrito, orientado para os outros. Nos países de língua espanhola, só recentemente foi possível operacionalizar esses aspectos, por isso foi proposto testar a adequação do modelo tridimensional integrando fatorialmente duas escalas de perfeccionismo infantil. Um total de 2249 menores participaram, completando as Escalas de Perfeccionismo Auto-Orientado e Perfeccionismo Social, e medidas de Arrogância e Depressão. Foi observado um ajuste válido e confiável do modelo de três fatores que incluiu parcelas e covariâncias entre os resíduos. A validade foi ainda evidenciada por correlações positivas de perfeccionismo com arrogância e depressão. Esses resultados demonstram que o modelo multidimensional pode ser generalizado para a população infantil.

Inteligencia emocional y estrategias de afrontamiento al estrés en personal de salud

Objetivo: Determinar la relación entre inteligencia emocional y las estrategias de afrontamiento al estrés en trabajadores asistenciales de un Hospital de Tercer Nivel de Atención durante el 2021. Material y método: Se realizó un estudio transversal analítico. Se utilizó dos encuestas: El test de COPE, el cual mide cómo afrontar el estrés y el Inventario de Coeficiente emocional de Bar-On, que mide el nivel de inteligencia emocional. La variable principal fue el afrontamiento al estrés; la independiente, la inteligencia emocional. Resultados: Se trabajó un total de 290 trabajadores asistenciales. La inteligencia emocional se correlacionó significativamente de manera positiva (Pearson = 0.6003) con el afrontamiento al estrés. Las estrategias de afrontamiento al estrés con mayor media fueron planificación, reinterpretación positiva y crecimiento, afrontamiento religioso. Estas estrategias tuvieron una correlación positiva con la inteligencia emocional, estas correlaciones fueron 0.5271, 0.5200 y 0.2051, respectivamente. Para el análisis de regresión múltiple, se observó que el promedio de puntos del Test de BarOn aumentó en 0.261 puntos por cada punto que incrementa el TEST de COPE (coef. = 0,261; IC95%: 0.215 - 0.307); ello ajustado por todas las covariables de interés. Conclusión: Existe una relación entre la inteligencia emocional y el afrontamiento al estrés; también, se encontró relación con las estrategias de afrontamiento al estrés.

Objective: To determine the relationship between emotional intelligence and stress coping strategies in health care workers of a Third Level of Care Hospital during 2021. Methods: An analytical cross-sectional study was carried out. Two surveys were used: the COPE test which measures how to cope with stress and the Bar-On Emotional Coefficient Inventory which measures the level of emotional intelligence. The main variable was coping with stress. The independent variable was emotional intelligence. Results: A total of 290 health care workers were worked. Emotional intelligence was significantly positively correlated (Pearson = 0.6003) with stress coping. The stress coping strategies with the highest mean were planning, positive reinterpretation and growth, and religious coping. These strategies had a positive correlation with emotional intelligence, these correlations were 0.5271, 0.5200 and 0.2051 respectively. For the multiple regression analysis, it was observed that the average BARON test score increased by 0.261 points for each point increase in the COPE TEST (coefficient = 0.261; 95%CI: 0.215 - 0.307); adjusted for all covariates of interest. Conclusion: There is a relationship between emotional intelligence and stress coping. A relationship was also found with stress coping strategies.

Physical activity level and factors associated with perceived stress among Peruvian university professors during the COVID-19 pandemic.

Introduction: The COVID-19 pandemic led to the transition to remote work, triggering variations in stress and physical activity (PA), associated with context-specific instability. Objective: To identify the association between perceived stress (PS) and the level of physical activity (PA) and explore its relationship with the sociodemographic, family, work and individual characteristics of professors working remotely during the COVID-19 pandemic. Material and methods: Cross-sectional analytical study based on a virtual survey of professors. PS was assessed using the Perceived Stress Scale (PSS-14), and PA using an International Physical Activity Questionnaire. The prevalence of high PS and the association with PA were estimated using a Poisson regression analysis with robust variance that estimated crude prevalence ratios (cPR) and adjusted prevalence ratios (aPR) with a 95% confidence interval (CI). Five models were developed to assess associations of PS and PA with sociodemographic, family, work, and individual variables. Results: The information of 191 professors was analyzed; 39.27% were women, aged 52 (41-60). The prevalence of high stress was 47.12%. The age and being head of household did not show significant individual associations with PS. However, the regression analysis assessing the association of PS and other factors showed that compared to the moderate PA group, a statistically significant association was found between stress and high PA (aPR = 0.19; 0.06-0.59), low PA (aPR = 1.43; 1.02-2.01), mainly influenced by age, being head of household and sleep quality. Conclusion: Stress was associated with PA level, family and individual factors. These findings allow identifying characteristics, such as being head of household, age and quality of sleep among teachers, as being associated with a higher probability of having high stress. Subsequent studies should consider the role of individuals and working conditions as part of occupational health surveillance, given the presence of hybrid education in the education sector.

Pipeline for transferring annotations between proteins beyond globular domains.

DisProt is the primary repository of Intrinsically Disordered Proteins (IDPs). This database is manually curated and the annotations there have strong experimental support. Currently, DisProt contains a relatively small number of proteins highlighting the importance of transferring annotations regarding verified disorder state and corresponding functions to homologous proteins in other species. In such a way, providing them with highly valuable information to better understand their biological roles. While the principles and practicalities of homology transfer are well-established for globular proteins, these are largely lacking for disordered proteins. We used DisProt to evaluate the transferability of the annotation terms to orthologous proteins. For each protein, we looked for their orthologs, with the assumption that they will have a similar function. Then, for each protein and their orthologs, we made multiple sequence alignments (MSAs). Disordered sequences are fast evolving and can be hard to align, therefore, we implemented alignment quality control steps ensuring robust alignments before mapping the annotations. We have designed a pipeline to obtain good-quality MSAs and to transfer annotations from any protein to their orthologs. Applying the pipeline to DisProt proteins, from the 1731 entries with 5623 annotations, we can reach 97,555 orthologs and transfer a total of 301,190 terms by homology. We also provide a web server for consulting the results of DisProt proteins and execute the pipeline for any other protein. The server Homology Transfer IDP (HoTIDP) is accessible at http://hotidp.leloir.org.ar.

High-dose chemotherapy with autologous stem cell transplantation for patients with extracranial germ cell tumors - experience of two Brazilian pediatric centers.

Malignant extracranial germ cell tumors (GCTs) are rare in pediatric patients and are usually extremely sensitive to chemotherapy. Relapsed or refractory tumors, although rare, established the need for second-line therapies, including high-dose chemotherapy with autologous stem cell transplantation (HDCT/ASCT). However, there are few data on its use in children with GCTs. We present a retrospective analysis of all patients diagnosed with extracranial GCTs who received HDCT/ASCT at two Brazilian pediatric cancer centers from May 1999 to December 2019. We identified a total of 34 patients with a median age at diagnosis of 2.8 years (range, 0 to 18.8), who received HDCT/ASCT. Most patients (73%) received carboplatin, etoposide and melphalan (CEM) as a HDCT regimen. Fourteen patients received a second-line conventional dose chemotherapy (CDCT), 14 received a third-line CDCT and five received even a fourth-line CDCT prior to HDCT/ASCT. After a median follow-up of 22.7 months (range, 0.3 to 198.1), 16 patients had died after tumor relapse/progression and 2 patients died from HDCT/ASCT toxicity. We observed a 5-year OS of 47.1% and 5-year EFS of 44.1%. The 5-year OS for patients referred for HDCT/ASCT with progressive disease was 10% compared to 62.5% for those who achieved disease control before HDCT/ASCT (p = 0.001). In our experience, heavily pretreated children and adolescents with extracranial GCTs achieved considerable survival rates with HDCT/ASCT since, at least, partial control of their disease was possible before starting HDCT/ASCT. The role of HDCT/ASCT in pediatric patients with GCTs should be investigated in prospective trials.

Can Contingency Management Solve the Problem of Adherence to Antiretroviral Therapy in Drug-Dependent Individuals?

Drug misuse among people living with HIV (human immunodeficiency virus) is associated with higher mortality. It is a frequently observed reason for treatment abandonment, with people who misuse drugs showing a 10 to 25 times higher risk of HIV than the general population. The authors conducted a systematic review and meta-analysis to assess the efficacy of contingency management (CM) to improve adherence to antiretroviral therapy in people living with HIV and substance use disorder (SUD). The inclusion criteria consisted of studies written in English, Italian, Spanish, German, and French; studies conducted with humans; and clinical trials that combined SUD treatment with CM for people living with HIV. Two hundred twenty-two articles were identified, five met all inclusion criteria, and three provided enough data to perform the meta-analysis. We considered treatment adherence by measuring the increase in the CD4 count as our primary outcome. We found a significant increase in treatment adherence in the patient group compared with the control groups during the intervention phase. Positive findings did not persist after the cessation of the incentives. The meta-analysis showed that the intervention improved patient adherence by 2.69 (95% confidence interval: [0.08, 0.51]; p = .007) compared with the control group during the intervention period. All short-term CM studies converged on a positive result for adherence to antiretroviral therapy.

Declarative knowledge in oral health: The case of the term 'centric occlusion'.

INTRODUCTION: The lack of academic agreement in the practical or clinical use of declarative knowledge can generate unnecessary confusion and miscommunication. The concept Centric Occlusion (CO) is part of the body of declarative knowledge in dentistry, but its definition remains unclear. OBJECTIVE: To ascertain the CO concept in articles published in dental journals as a study case for the dentistry "corpus" of declarative knowledge. METHODOLOGY: The alternative definitions of CO used by the GPT (Glossary of Prosthodontic Terms) from 1956-1977, 'CO as a synonym for maximum intercuspal contact (MIC)', or by the GPT from 1987-2017, 'CO may or may not coincide with MIC', were searched in the articles. The association between the CO definition used and variables such as article aims, journal scope and authors specialty was assessed. RESULTS: Eight hundred and twelve articles were analysed. The widespread use of CO as synonym of MIC was the main finding and was significantly associated to the Orthodontics field. The CO definition according to the GPT 1987-2017 was less frequently observed but appeared in all dentistry fields, showing a significant association with the Oral Rehabilitation field. The difficulty of incorporating the current definition of CO (by GPT) into the main clinical discussions was evidenced all the long of the review process. CONCLUSION: The lack of consensus in the concept use was confirmed by the present study case, showing the influence of specific fields in Oral Health declarative knowledge. This methodology can provide a tool to the academy to assess controversial terms or concepts in Oral Health education, thus facilitating the critical and reflexive learning by students.

Anatomic nomenclature and 3-dimensional regional model of the human ovary: call for a new paradigm.

The ovaries are the female gonads that are crucial for reproduction, steroid production, and overall health. Historically, the ovary was broadly divided into regions defined as the cortex, medulla, and hilum. This current nomenclature lacks specificity and fails to consider the significant anatomic variations in the ovary. Recent technological advances in imaging modalities and high-resolution omic analyses have brought about the need for revision of the existing definitions, which will facilitate the integration of generated data and enable the characterization of organ subanatomy and function at the cellular level. The creation of these high-resolution multimodal maps of the ovary will enhance collaboration and communication among disciplines and between clinicians and researchers. Beginning in March 2021, the Pediatric and Adolescent Gynecology Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development invited subject-matter experts to participate in a series of workshops and meetings to standardize ovarian nomenclature and define the organ's features. The goal was to develop a spatially defined and semantically consistent terminology of the ovary to support collaborative, team science-based endeavors aimed at generating reference atlases of the human ovary. The group recommended a standardized, 3-dimensional description of the ovary and an ontological approach to the subanatomy of the ovary and definition of follicles. This new greater precision in nomenclature and mapping will better reflect the ovary's heterogeneous composition and function, support the standardization of tissue collection, facilitate functional analyses, and enable clinical and research collaborations. The conceptualization process and outcomes of the effort, which spanned the better part of 2021 and early 2022, are introduced in this article. The institute and the workshop participants encourage researchers and clinicians to adopt the new systems in their everyday work to advance the overarching goal of improving human reproductive health.

Bibliometric analysis of main diseases due to exposure to altitude in the world / Análise bibliométrica das principais doenças decorrentes da exposição à altitude no mundo

Introduction: Around 140 million people in the world live-in high-altitude regions; however, there are few bibliometric studies. Objective: Describe the scientific production of the main diseases due to exposure to altitude in the world. Methods: Observational study, bibliometric type. After a systematic search in Scopus, original articles were included, whose main variable was mountain sickness, high-altitude cerebral edema and high-altitude pulmonary edema. Characteristics of each study were manually extracted and analyzed using descriptive statistics. Results: 2305 articles were found on mountain sickness (n=1531), high-altitude pulmonary edema (n=549) and high-altitude cerebral edema (n=225), respectively, in Scopus. Regarding the most influential journal was High Altitude Medicine and Biology in all three diseases, the country with the highest number of articles was the United States (458, 168 and 75), the most used language was English (91.31%, 85.33% and 84.19%), the author with the highest number of publications was Bartsh P. (2.94%, 18.60% and 3.42%) and most of the articles were open access (41.08%, 42.06% and 76.53%), respectively. Conclusion: The scientific production of original articles on mountain sickness, high-altitude pulmonary edema and high-altitude cerebral edema in Scopus has increased in recent years; however, it is still scarce compared to other diseases.

Introdução: Cerca de 140 milhões de pessoas no mundo vivem em regiões de grande altitude, porém, existem poucos estudos bibliométricos. Objetivo: Descrever a produção científica sobre as principais doenças decorrentes da exposição à altitude no mundo. Métodos: Estudo observacional, do tipo bibliométrico. Após busca sistemática no Scopus, foram incluídos artigos originais, cuja variável principal foi mal da montanha, edema cerebral de altitude e edema pulmonar de altitude. As características de cada estudo foram extraídas manualmente e analisadas por meio de estatística descritiva. Resultados: Foram encontrados 2.305 artigos sobre mal da montanha (n=1.531), edema pulmonar de altitude (n=549) e edema cerebral de altitude (n=225), respectivamente no Scopus. Em relação ao periódico mais influente foi High Altitude Medicine and Biology nas três doenças, o país com maior número de artigos foi os Estados Unidos (458, 168 e 75), o idioma mais utilizado foi o inglês (91,31%, 85,33% e 84,19%), o autor com maior número de publicações foi Bartsh P. (2,94%, 18,60% e 3,42%) e a maioria dos artigos foi de acesso aberto (41,08%, 42,06% e 76,53%), respectivamente. Conclusão: A produção científica de artigos originais sobre mal da montanha, edema pulmonar de altitude e edema cerebral de altitude em Scopus tem aumentado nos últimos anos, porém ainda é escassa em comparação com outras doenças

Glosario básico actualizado de términos odontológicos de prótesis dental. Inglés - Español / Updated basic prosthodontics terms glossary. English-Spanish

RESUMEN La estomatología como rama de las ciencias médicas no escapa al impacto del desarrollo de la ciencia y la técnica donde se crean grandes volúmenes de información científica que en la mayor parte de los casos su divulgación y/o comunicación provienen de países de habla inglesa o se generan en ese idioma, siendo muy necesario para el profesional al permitirle comprender y comunicar mejor la ciencia. Son variados los medios y métodos que el profesional utiliza para apropiarse de dichos conocimientos, los glosarios de términos en inglés de una misma rama o de un mismo campo de estudio son una herramienta válida de trabajo en el aprendizaje y uso de los idiomas al permitir de forma rápida el significado de palabras desde el contexto apropiado. Este glosario se ha concebido como un instrumento de trabajo y de consulta para estudiantes y profesionales en el campo de la Odontología, recopilando casi 150 términos específicamente en la rama de la Prótesis Dental, no se pretende exponer todos los vocablos y frases pertenecientes a la misma sería imposible, se excluyen los términos cuya escritura semeje al español excepto aquellos que su significado no sea el mismo. Recopila términos frecuentes y actuales necesarios para la comprensión de textos en esa rama.

ABSTRACT Dentistry as a branch of Medical Sciences is influenced by a great deal of scientific information written in English, compelling the dental professionals to be updated in English language for a better science understanding. One of the means and methods to fulfill such goal is through English terms glossaries in which in a very simple way provide the meaning of the most frequent and important words of a certain area of knowledge. This Glossary focused on Prosthodontics has been conceived mainly as a working and reference tool for dental students and post- graduated professionals, gathering almost 150 english terms focused on that branch of dentistry. Some terms have been left out of the Glossary because of their similarity to the Spanish equivalent. However, others were included because of their special translation. It is not an attempt to give all the words and phrases related to dental prosthesis; the aim is only to offer a quick and an updated reference on the most common and indispensable terms in this field.

Data standardization of plant-pollinator interactions.

BACKGROUND: Animal pollination is an important ecosystem function and service, ensuring both the integrity of natural systems and human well-being. Although many knowledge shortfalls remain, some high-quality data sets on biological interactions are now available. The development and adoption of standards for biodiversity data and metadata has promoted great advances in biological data sharing and aggregation, supporting large-scale studies and science-based public policies. However, these standards are currently not suitable to fully support interaction data sharing. RESULTS: Here we present a vocabulary of terms and a data model for sharing plant-pollinator interactions data based on the Darwin Core standard. The vocabulary introduces 48 new terms targeting several aspects of plant-pollinator interactions and can be used to capture information from different approaches and scales. Additionally, we provide solutions for data serialization using RDF, XML, and DwC-Archives and recommendations of existing controlled vocabularies for some of the terms. Our contribution supports open access to standardized data on plant-pollinator interactions. CONCLUSIONS: The adoption of the vocabulary would facilitate data sharing to support studies ranging from the spatial and temporal distribution of interactions to the taxonomic, phenological, functional, and phylogenetic aspects of plant-pollinator interactions. We expect to fill data and knowledge gaps, thus further enabling scientific research on the ecology and evolution of plant-pollinator communities, biodiversity conservation, ecosystem services, and the development of public policies. The proposed data model is flexible and can be adapted for sharing other types of interactions data by developing discipline-specific vocabularies of terms.

Phenotypic and mutational spectrum of ROR2-related Robinow syndrome.

Robinow syndrome is characterized by a triad of craniofacial dysmorphisms, disproportionate-limb short stature, and genital hypoplasia. A significant degree of phenotypic variability seems to correlate with different genes/loci. Disturbances of the noncanonical WNT-pathway have been identified as the main cause of the syndrome. Biallelic variants in ROR2 cause an autosomal recessive form of the syndrome with distinctive skeletal findings. Twenty-two patients with a clinical diagnosis of autosomal recessive Robinow syndrome were screened for variants in ROR2 using multiple molecular approaches. We identified 25 putatively pathogenic ROR2 variants, 16 novel, including single nucleotide variants and exonic deletions. Detailed phenotypic analyses revealed that all subjects presented with a prominent forehead, hypertelorism, short nose, abnormality of the nasal tip, brachydactyly, mesomelic limb shortening, short stature, and genital hypoplasia in male patients. A total of 19 clinical features were present in more than 75% of the subjects, thus pointing to an overall uniformity of the phenotype. Disease-causing variants in ROR2, contribute to a clinically recognizable autosomal recessive trait phenotype with multiple skeletal defects. A comprehensive quantitative clinical evaluation of this cohort delineated the phenotypic spectrum of ROR2-related Robinow syndrome. The identification of exonic deletion variant alleles further supports the contention of a loss-of-function mechanism in the etiology of the syndrome.

Comprehensive evaluation of Salud Escolar a health school program in Mexico: Rationale, design and methods.

The prevalence of obesity and overweight in Mexican children and adolescents is high (greater than 30%) and lifestyle behaviors are far from achieving health recommendations. Salud Escolar is a complex cross-sectoral multi-level policy-based program in Mexico aiming to support schoolchildren healthy behaviors. We describe the rationale, design and methods for the comprehensive evaluation of Salud Escolar during its first phase of implementation. Using a mixed-methods approach and the logic model of Salud Escolar as a guide, a comprehensive evaluation involving 3 types of evaluations was designed: 1) A design evaluation before program implementation, to determine the consistency between the design of Salud Escolar and the problem to be addressed (i.e., childhood obesity), 2) An implementation evaluation to assess potential execution bottlenecks, and 3) An outcomes evaluation, to measure short-term (i.e., knowledge, attitudes and practices related to healthy eating, drinking plain water and doing regular physical activity) and intermediate outcomes (i.e., fruit and vegetable intake, water consumption and daily moderate to vigorous physical activity). This evaluation will provide essential knowledge about program design and implementation processes, which are vital for drawing robust conclusions about the effectiveness of the program. Results and lessons learned from this comprehensive evaluation will provide evidence to improve Salud Escolar program and facilitate its upscaling process and may provide relevant information for school-based programs in other places sharing socio-contextual conditions.

Effect of Different Bleaching Gels Thickeners on Cytotoxicity to Human Gingival Fibroblasts and Enamel Physical Properties: an in Situ Study.

Objective: This study evaluated in vitro, the effects of carbamide peroxide 10% (CP) associated with Carbopol® (CP-ct) and Aristoflex® (CP-at) thickeners on human gingival fibroblasts (HGF) cytotoxicity and assessed in situ their effects on dental enamel. Material and methods: The cytotoxicity was analyzed using MTT - Vybrant® proliferation test. For in situ stage, 144 bovine enamel/dentin blocks were randomized into seven groups (n=12). Samples were stained, fixed in intraoral palatal devices and bleached for 4 h, during 14 days, with: Carbopol thickener (ct), Aristoflex thickener (at), CP-ct, CP-at, CP without thickener (CP-wot), Commercial CP (CP-com). The samples had their microhardness (SMH), roughness (Ra) and color analyzed using a microdurometer, a rugosimeter and a spectrophotometer, respectively. The analyses were performed at baseline and 24-h after completion of tooth bleaching. Results: Different thickeners were similar regarding their cytotoxicity. The experimental gels with Carbopol exhibited lower SMH values, while the groups treated with CP exhibited higher Ra values. For the color change results, the groups treated with CP had values above the acceptability and perceptibility limits. Conclusion: CP-at was able to promote an effective bleaching with less alterations of the tooth surface compared to the CP-ct. Hence, Aristoflex stands as a promising thickener in conjunction with CP in order to preserve the physical properties of dental enamel after home bleaching.

Developmental kindergarten classroom intervention for spatial relational terms

ABSTRACT Purpose Relational ability is a key attribute of language. Knowledge of relational terms, including spatial terms, can facilitate development of relational ability. Acquisition of spatial terms can be challenging and necessitates experience and input due to the abstractness of the concepts. Service delivery models for school-based speech-language pathologists (SLPs) are changing from traditional "pull-out" therapy to intervention in the classroom. Response to Intervention (RtI) and multi-tiered system of support (MTSS) frameworks have expanded SLPs' roles to working with all children at-risk for academic difficulties. Methods Given the importance of spatial terms, and the changing roles and service delivery models for school-based SLPs, this investigation evaluated a six-week classroom-based intervention targeting spatial terms in a developmental kindergarten classroom of five-year-old children. Results At post-test, more than half of the children who did not understand the targeted spatial terms at pre-test demonstrated understanding of the words first, front, last, behind, center, below, under, and right by correctly identifying pictures representing these words. Around and left were the only two words learned by fewer than half of the children. Conclusion These findings augment research used by SLPs providing language support to children within the first tier of Response to Intervention or multi-tiered system of support.

Comparison of Two Types of Pit and Fissure Sealants in Reducing the Incidence of Dental Caries Using a Split-Mouth Design.

OBJECTIVES: To evaluate the effectiveness of two pit and fissure sealants (PFS) in reducing the incidence of dental caries in schoolchildren. MATERIAL AND METHODS: A randomized split-mouth experimental design was used in a sample of 140 subjects assigned to two groups. The sealants used were Clinpro©3M and BeautiSealant©Shofu placed in first permanent molars (FPMs). Each sealant was compared to molars in the controls to determine effectiveness over a period of 6 months. The study had a 12.9% loss to follow-up. No statistically significant differences (p>0.05) were observed for sex, age, baseline dmft, or type of sealants. Nonparametric tests were used for statistical analysis. RESULTS: Average dmft index at baseline was 4.10±3.16. Lower incidence of caries was observed in FPMs with pit and fissure sealants (p<0.01), regardless of the type used. When sealants remained intact there was a lower caries incidence compared to sealants partially or completely missing - but differences were only significant for FPM 16. Caries incidence was higher for BeautiSealant sealed teeth than for Clinpro's, but only statistically significant in FPMs 16, 36 and 46 (p< 0.05). Caries incidence was higher in those cases with a higher baseline dmft but it only reached statistical significance in FPMs 26 and 36. Relative risks for dental caries were lower in sealed teeth (p<0.01). CONCLUSIONS: Pit and fissures sealants are an effective preventive treatment to reduce caries during a 6-month follow-up in schoolchildren 6 to 8 years of age, regardless of the type of sealant used. The sealant brand that showed greater effectiveness in terms of prevention and retention was Clinpro©3M.