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1.
Front Nutr ; 11: 1370611, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38966414

RESUMO

Introduction: The demand for fresh-cut water chestnuts, a convenient and nutritive vegetable, is increasing in market. However, the slicing of water chestnuts can cause mechanical damage to tissue, which results in quality deterioration. We aimed to select the optimal treatment through a comprehensive comparison of the preservation effect of acetic acid, which could prolong the shelf life of fresh-cut water chestnuts and improve their storage quality. Methods: A comprehensive evaluation was conducted using the gray-correlation method based on the variation-coefficient weight to observe the treatment of 0, 2 and 5% acetic acid. Their effects on color, weight loss rate, and the content of ascorbic acid, total sugar, reducing sugar, soluble protein, and free amino acid were determined. Results: The color, weight loss rate, and nutritional content of fresh-cut chestnuts varied under different processing and storage times. When stored for more than 4 days, the b* value, and the content of total sugar and soluble protein in CK were higher than those in 2% or 5% acetic acid, but the weight loss rate, and the content of ascorbic acid and free amino acid in CK were less than those in acetic acid treatments. Considering various indicators, it was difficult to determine which treatment to choose for fresh-cut water chestnut preservation. The gray-correlation analysis results indicated that when stored for 8, 12, or 16 days, the gray-correlation degree of 5% acetic acid was the highest, while that of the control was the lowest. It could be directly concluded by the gray-correlation degree that when the storage time exceeded 4 days, acetic acid could be used to improve storage quality, and 5% acetic acid had a better preservation effect than 2%. Fresh-cut water chestnuts can be stored for 4 days without the need for acetic acid treatment. Conclusion: These findings could provide information and comprehensive evaluation methods for the preservation of fresh-cut fruits and vegetables. The next step is to evaluate the preservation effect of acetic acid by measuring its effects on other indicators of fresh-cut water chestnuts (e.g., flavonoids, and microorganisms), providing ideas for the research of preservatives.

2.
Urolithiasis ; 52(1): 53, 2024 Apr 02.
Artigo em Inglês | MEDLINE | ID: mdl-38564004

RESUMO

The stone density (SD) is not the same in all parts of the stone due to the heterogeneous nature of the stone and the shock wave (SW) passes through tissues of many different densities until it reaches the stone. These factors affect the success of Extracorporeal Shock Wave Lithotripsy (ESWL). We aimed to evaluate the effect of the Variation Coefficient of Stone Density (VCSD) and Renal Cortical Tickness (RCT) on the success of ESWL. Between 2020 and 2023, 510 patients who underwent ESWL were divided into 2 groups treatment success (n:304) and treatment failure (n:206). Non-Contrast Computed Tomography (NCCT) imaging values of hydronephrosis degree of the kidney, stone location, stone volume (SV), stone-skin distance (SSD), SD, Standard deviation of Stone Density (SDSD), VCSD, RCT, Soft-Tissue Thickness (STT), Muscle Thickness (MT) were analyzed. VCSD value was obtained by dividing SDSD by SD. Along the SW, tissues were divided into three components: kidney (renal cortex), muscle and other soft tissues. RCT, MT and SSD were measured at three different angles (0°, 45°, and 90°) and these 3 lengths were averaged. In univariate analysis, Body Mass Index (BMI), SV, SD, VCSD, SSD, RCT and STT were demonstrated to affect ESWL success. In multivariate analysis, low BMI, SV, SD, RCT and large VCSD were significant independent predictors of ESWL success. Among these parameters, VCSD had the highest prediction accuracy, followed by SD, SV, RCT and BMI, respectively. This study demonstrated that VCSD value and RCT are predictive parameters in determining the treatment of patients with urinary calculi and selecting suitable ESWL candidates.


Assuntos
Litotripsia , Cálculos Urinários , Humanos , Tomografia Computadorizada por Raios X , Córtex Renal/diagnóstico por imagem , Rim
3.
Plants (Basel) ; 13(5)2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38475552

RESUMO

The possible influence of global climate changes on agricultural production is becoming increasingly significant, necessitating greater attention to improving agricultural production in response to temperature rises and precipitation variability. As one of the main winter wheat-producing areas in China, the temporal and spatial distribution characteristics of precipitation, accumulated temperature, and actual yield and climatic yield of winter wheat during the growing period in Shanxi Province were analysed in detail. With the utilisation of daily meteorological data collected from 12 meteorological stations in Shanxi Province in 1964-2018, our study analysed the change in winter wheat yield with climate change using GIS combined with wavelet analysis. The results show the following: (1) Accumulated temperature and precipitation are the two most important limiting factors among the main physical factors that impact yield. Based on the analysis of the ArcGIS geographical detector, the correlation between the actual yield of winter wheat and the precipitation during the growth period was the highest, reaching 0.469, and the meteorological yield and accumulated temperature during this period also reached its peak value of 0.376. (2) The regions with more suitable precipitation and accumulated temperature during the growth period of winter wheat in the study area had relatively high actual winter wheat yields. Overall, the average actual yield of the entire region showed a significant increasing trend over time, with an upward trend of 47.827 kg ha-1 yr-1. (3) The variation coefficient of winter wheat climatic yield was relatively stable in 2008-2018. In particular, there were many years of continuous reduction in winter wheat yields prior to 2006. Thereafter, the impact of climate change on winter wheat yields became smaller. This study expands our understanding of the complex interactions between climate variables and crop yield but also provides practical recommendations for enhancing agricultural practices in this region.

4.
Molecules ; 28(13)2023 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-37446935

RESUMO

This study aimed to improve the steaming process of black sesame seeds. A comprehensive evaluation was conducted using the grey-correlation method based on the variation-coefficient weight to observe the treatments of normal-pressure (NPS) and high-pressure (HPS) steaming (with/without soaking in water) for nine cycles. Their effects on the contents of water, protein, fat, ash, melanin, sesamin, and sesamolin of black sesame seeds, as well as the sensory score of the black sesame pill, were determined. We found that with varied steaming methods and increased steaming cycles, the contents of the nutritional and functional components of black sesame seeds and the sensory score of the black sesame pill differed. The results of the variation-coefficient method showed that water, protein, fat, ash, melanin, sesamin, sesamolin, and sensory score had different effects on the quality of black sesame seeds with weighting factors of 34.4%, 5.3%, 12.5%, 11.3%, 13.9%, 11.3%, 7.8%, and 3.5%, respectively. The results of two-factor analysis of variance without repeated observations indicated that the grey-correlation degree of HPS was the largest among the different steaming treatments, and the following sequence was HPS after soaking in water (SNPS), NPS, and SNPS. There was no significant difference between NPS and SNPS (p < 0.05). Moreover, with increased cycles, the value of the grey-correlation degree increased. The comprehensive score of the procedure repeated nine times was significantly higher than other cycles (p < 0.05). The results of the grey-correlation degree and grade analysis showed that the best steaming process of black sesame seeds was HPS for nine cycles, followed by HPS for eight cycles and NPS after soaking in water (SNPS) for nine cycles. These findings could provide a scientific basis for replacing SNPS with HPS to simplify steaming and realize the parametric steaming of black sesame seeds, and thus, ensure the quality of black-sesame products.


Assuntos
Lignanas , Sesamum , Sesamum/metabolismo , Melaninas/metabolismo , Lignanas/metabolismo , Vapor , Sementes/química
5.
Spectrochim Acta A Mol Biomol Spectrosc ; 285: 121917, 2023 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-36174403

RESUMO

This study was undertaken to establish an integrated quality control method based on the fingerprint of different testing instruments and a four-dimensional antioxidant activity profile. Firstly, the comprehensive ratio quantitative fingerprint method was used to rapidly calculate the similarity of GC fingerprint, UV-vis quantized fingerprint, HPLC fingerprint and ATR-FT-IR quantized fingerprint. In addition, a comprehensive evaluation strategy was proposed using the variation coefficient weighting algorithm, incorporating four complementary inputs, to achieve highly accurate analysis. At the same time, multi-markers assay by monolinear method was used for the first time for the quantitative analysis of multiple components. Based on this, the fingerprint-efficacy relationship was investigated, and substances that might be biologically active and the wavelength range of their distribution were predicted using the online-HPLC-DPPH-FIA method in conjunction with a PLS model built from individual and combined data matrices. The results showed that all 20 batches of samples were within 1-3 grades, with good quality consistency. According to index E, the samples' overall antioxidant capacity was also highly correlated with the year of production. The four-dimensional antioxidant activity profile also led to the conclusion that variations in antioxidant characteristics were caused by differences in the concentration and volatility of particular bioactive chemicals. Finally, mid-level data fusion produced better classification results than a single technique, further demonstrating the synergistic effects that may occur when the four types of data were combined. This study demonstrated that the combination of GC, UV-vis, ATR-FT-IR and HPLC can be used for the consistency control of herbal preparations and can elucidate the potential in predicting the antioxidant capacity of herbal preparations.


Assuntos
Antioxidantes , Medicamentos de Ervas Chinesas , Antioxidantes/química , Medicamentos de Ervas Chinesas/química , Preparações de Plantas , Espectroscopia de Infravermelho com Transformada de Fourier , Cromatografia Líquida de Alta Pressão/métodos
6.
Khirurgiia (Mosk) ; (8): 38-44, 2022.
Artigo em Russo | MEDLINE | ID: mdl-35920221

RESUMO

OBJECTIVE: To evaluate the role of platelet variation coefficient in prediction of severity of acute pancreatitis (AP). MATERIAL AND METHODS: The study included 90 patients with AP who admitted to the Tula City Emergency Hospital between 2018 and 2019. Patients had no signs of renal and hepatic insufficiency, cancer, blood diseases, inherited platelet disorders, previous splenectomy, antiplatelet and anticoagulant therapy. Mortality of patients with mild-to-moderate AP was 0%, severe pancreatic necrosis - 5.26%, extremely severe pancreatic necrosis - 92.3%. We analyzed the number and volume of platelets, thrombocytocrit and volume-adjusted distribution of platelets. All parameters were assessed after 1, 3, 7, 14, 21, 28 and 35 days. RESULT: There was a significant correlation between AP severity and the number, volume and volume-adjusted distribution of platelets. Reduced platelet count, enlarged cells and heterogeneous volumes of platelets indicate severe course of pancreatitis. Identification of these changes as early as 3 days of disease is of great clinical importance. Platelet variation coefficient (PVC) is proposed to predict severity of AP. We found a direct correlation between IL-6 and PVC (correlation coefficient 0.78). CONCLUSION: The proposed PVC is available and easy to use for prediction of AP severity. It allows you to assess the course of acute destructive pancreatitis and effectiveness of treatment after the first three days of therapy. You can improve prediction of AP using this value.


Assuntos
Pancreatite Necrosante Aguda , Humanos , Doença Aguda , Pancreatite Necrosante Aguda/diagnóstico , Pancreatite Necrosante Aguda/terapia , Prognóstico , Índice de Gravidade de Doença
7.
Front Sports Act Living ; 4: 871727, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35837247

RESUMO

Choosing an appropriate pacing strategy is important for good triathlon performance. In the Japan Student Triathlon Championship held in 2020, the men's category was divided into two groups, which was a different racing style from the previous races that all athletes start at the same time. It is highly likely that the performance level will vary as grouping was performed according to the competence of each player. The aim of this study was to understand the relationship of the total time and time of each leg between the superior performance group and the inferior performance group, as well as the difference in pacing during running in participants of the 2020 Japan University Triathlon Championship Watarase Competition, which was held under unconventional conditions. We analyzed 153 male athletes (Group A: 77; Group B: 76) who completed the race. The total race time, leg time, and average speed in each leg and its variation coefficient were evaluated based on the official results of the competition and footage recorded during the race. The results showed that the total time and leg time for each leg were significantly shorter in Group A compared to those in Group B (p < 0.05). In both groups, the Lap 4 run was significantly slower than those of Laps 1-3 (p < 0.05), while there was no significant difference in the running speed to average speed ratio across all laps between the groups (p < 0.05). Thus, there was a difference in running speed between the groups, but no significant difference in pacing. The results of this study serve as basic data for examining superior pacing strategies, although further studies on a wide range of competition levels are necessary.

8.
Acta Pharm Sin B ; 12(1): 451-466, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35127398

RESUMO

The combination of chemotherapy and immunotherapy motivates a potent immune system by triggering immunogenic cell death (ICD), showing great potential in inhibiting tumor growth and improving the immunosuppressive tumor microenvironment (ITM). However, the therapeutic effectiveness has been restricted by inferior drug bioavailability. Herein, we reported a universal bioresponsive doxorubicin (DOX)-based nanogel to achieve tumor-specific co-delivery of drugs. DOX-based mannose nanogels (DM NGs) was designed and choosed as an example to elucidate the mechanism of combined chemo-immunotherapy. As expected, the DM NGs exhibited prominent micellar stability, selective drug release and prolonged survival time, benefited from the enhanced tumor permeability and prolonged blood circulation. We discovered that the DOX delivered by DM NGs could induce powerful anti-tumor immune response facilitated by promoting ICD. Meanwhile, the released mannose from DM NGs was proved as a powerful and synergetic treatment for breast cancer in vitro and in vivo, via damaging the glucose metabolism in glycolysis and the tricarboxylic acid cycle. Overall, the regulation of tumor microenvironment with DOX-based nanogel is expected to be an effectual candidate strategy to overcome the current limitations of ICD-based immunotherapy, offering a paradigm for the exploitation of immunomodulatory nanomedicines.

9.
Math Biosci Eng ; 19(1): 855-872, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34903016

RESUMO

One of the most dominant and feasible technique is called the PHF setting is exist in the circumstances of fuzzy set theory for handling intricate and vague data in genuine life scenario. The perception of PHF setting is massive universal is compared to these assumptions, who must cope with two or three sorts of data in the shape of singleton element. Under the consideration of the PHF setting, we utilized some SM in the region of the PHF setting are to diagnose the PHFDSM, PHFWDSM, PHFJSM, PHFWJSM, PHFCSM, PHFWCSM, PHFHVSM, PHFWHVSM and demonstrated their flexible parts. Likewise, a lot of examples are exposed under the invented measures based on PHF data in the environment of medical diagnosis to demonstrate the stability and elasticity of the explored works. Finally, the sensitive analysis of the presented works is also implemented and illuminated their graphical structures.


Assuntos
Tomada de Decisões , Lógica Fuzzy , Algoritmos
10.
Toxicol Rep ; 8: 1488-1497, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34401359

RESUMO

Dennettia tripetala G. Baker (Annonaceae), is a plant with nutritional, social economy, and medicinal values. Its rising medicinal profile makes this plant a prospect in drug discovery. However, the reported strong addictive potential among habitual consumers makes the need to establish its safety imperative. In this report, we evaluated the safety profile of the essential oil of the seed of D. tripetala (EODS) in nulliparous female Wistar rats using in vivo single and repeated dose toxicity profiling, as well as in silico toxicity profiling of its known seed oil derived phytoconstituents. Our results showed consistent significant dose-dependent alterations in relative body weights, organ-body and organ-brain weight ratios, haematological and biochemical indices, as well as liver and kidney histoarchitectures, following single and repeated oral administrations. Significant alterations in liver and kidney histoarchitectures were consistent with the observed significant increase in AST/ALT ratio, suggesting deleterious effects of EODS on the kidney and liver. However, the lack of alterations in the histoarchitectures of the hippocampus and hypothalamus suggests that the brain may not have been adversely affected. Also, the in silico analysis suggests that hepatotoxic effects of EODS may be linked to Benzylnitrile, Humulene, Linalool, (Z)-ß-Ocimene. In addition, the failure of ß-Phenylnitroethane, the most abundant phytoconstituent of EODS, to pass phases I and II in silico toxicity screening, and the presence of Caryophyllene oxide, a known toxic compound, coupled with the predicted binding of both to DNA and protein, low LD50 and high percent mortality at 250 mg/kg of repeated doses, further confirmed the potentially toxic nature of EODS. We concluded that based on our in vivo and in silico observations, there is an urgent need for public education to regulate the excessive consumption of the seeds of D. tripetala.

11.
Med Devices (Auckl) ; 14: 97-103, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33833594

RESUMO

BACKGROUND: High glycemic Variability (HGV) has become a stronger predictor of hypoglycemia. However, clinical factors associate with HGV still are unknown. OBJECTIVE: To determine clinical variables that were associated with a coefficient of variation (CV) above 36% evaluated by continuous glucose monitoring (CGM) in a group of patients with diabetes mellitus. METHODS: A cohort of patients with type 2 diabetes (T2D) was evaluated. Demographic variables, HbA1c, glomerular filtration rate (GFR) and treatment regimen were assessed. A bivariate analysis was performed, to evaluate the association between the outcome variable (CV> 36%) and each of the independent variables. A multivariate model was constructed to evaluate associations after controlling for confounding variables. RESULTS: CGM data from 274 patients were analyzed. CV> 36% was present in 56 patients (20.4%). In the bivariate analysis, demographic and clinical variables were included, such as time since diagnosis, hypoglycemia history, A1c, GFR and treatment established. In the multivariate analysis, GFR <45 mL/min (OR 2.81; CI 1.27,6.23; p:0.01), A1c > 9% (OR 2.81; CI 1.05,7.51; p:0.04) and hypoglycemia history (OR 2.09; CI 1.02,4.32; p:0.04) were associated with HGV. Treatment with iDPP4 (OR 0.39; CI 0.19,0.82; p:0.01) and AGLP1 (OR 0.08; CI 0.01,0.68; p:0.02) was inversely associated with GV. CONCLUSION: Clinical variables such as GFR <45 mL/min, HbA1C>9% and a history of hypoglycemia are associated with a high GV. Our data suggest that the use of technology and treatments able to reduce glycemic variability could be useful in this population to reduce the risk of hypoglycemia and to improve glycemic control.

12.
Polymers (Basel) ; 13(8)2021 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-33917663

RESUMO

Based on the dynamic cycle condition test of a 4.5 kW fuel cell stack, the performance attenuation and individual cell voltage uniformity of the proton exchange membrane fuel cell (PEMFC) stack was evaluated synthetically. The performance decay period of the fuel cell stack was 180-600 h, the decrease of voltage and power was evaluated by rate and amplitude. The results show that the performance of the fuel cell stack decreased with the increase of test time and current density. When the test was carried out to 600 h, under rated operating conditions, the voltage attenuation rate was 130 µV/h, and the voltage reduced by 71 mV, with a decrease of 10.41%. The power attenuation rate was 0.8 W/h, with a decrease of 10.42%. The statistical parameter variation coefficient was used to characterize the voltage consistency of individual cells. It was found that the voltage uniformity is worse at the high current density point and with a long-running process. The variation coefficient was 3.1% in the worst performance.

13.
Sci Total Environ ; 750: 142277, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33182190

RESUMO

Flood loss assessment is an important part of urban flood risk management, and the establishment of disaster damage curve is the key of loss assessment. Because of the limitation of data, it is difficult for cities lacking disaster data to fit the damage curve through historical data. Generally, transferring the damage curve among regions is an effective method, but there are problems of data reference and statistical uncertainty. In view of the inland plain cities lacking disaster data, the damage factor of the data reference area can be transferred to the study area by referring to the principle of analogy. Then, based on the optimization principle of the minimum variation coefficient and the maximum beta distribution probability, the citation error and statistical error in the damage factor quotation were reduced, and the relatively accurate damage factor in the study area was obtained, and then the water depth - damage factor curve was established. Thus, a generalized damage curve fitting method for cities lacking disaster data was formed, which took the regional index values as the input parameters and the damage curves as the output results. Finally, taking Zhengzhou City, China as the study area, the loss curves of 10 property types were calculated. Compared with the original data, the average variation coefficient of the optimal scheme set was reduced by 0.1; the probability of the optimal value was increased by 1.39% compared with the average value. In addition, the method test was conducted in Jinan, China, where the data were available, and it was found that the three types of errors were significantly lower than the traditional comparison method of single city as reference object. This study is expected to provide a scientific reference for the establishment of flood damage curve in cities or areas lacking disaster data.

14.
ACS Sens ; 5(7): 2025-2035, 2020 07 24.
Artigo em Inglês | MEDLINE | ID: mdl-32608225

RESUMO

In previous studies, the selection of optimal gas-sensing materials for detecting target gases mainly relied on their response value, but other indices, such as the recovery capability of materials, have usually been overlooked. Here, we propose a new method for evaluating sensor effectiveness that includes a broader range of performance indices. In this study, four gas sensors based on metal-oxide semiconductors (WO3, CeO2, In2O3, and SnO2) were used as examples, and their performance in the detection of four decomposition products of sulfur hexafluoride (SF6) was investigated. After gas-sensing experiments, values for working temperature, response value, and recovery capability were obtained. A multivariate evaluation method of mixing principal component analysis, information entropy, and variation coefficient was developed to calculate the weights of various indices, and the sensors' optimal working temperatures could be identified quantitatively. Using five variables (working temperature, response value, recovery capability, fluctuation rate, and detection limit), we continued to apply this multivariate evaluation method to calculate the weights and acquire comprehensive scores for the four sensors. Finally, these scores were used to identify the optimal materials for detecting SF6 decomposition products. This procedure has the potential for selecting the best sensors for other gases.


Assuntos
Gases , Hexafluoreto de Enxofre , Óxidos , Semicondutores , Temperatura
15.
Clin Chem ; 66(5): 727-736, 2020 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-32353129

RESUMO

BACKGROUND: With increased interest in lipoprotein(a) (Lp[a]) concentration as a target for risk reduction and growing clinical evidence of its impact on cardiovascular disease (CVD) risk, rigorous analytical performance specifications (APS) and accuracy targets for Lp(a) are required. We investigated the biological variation (BV) of Lp(a), and 2 other major biomarkers of CVD, apolipoprotein A-I (apoA-I) and apolipoprotein B-100 (apoB), in the European Biological Variation Study population. METHOD: Serum samples were drawn from 91 healthy individuals for 10 consecutive weeks at 6 European laboratories and analyzed in duplicate on a Roche Cobas 8000 c702. Outlier, homogeneity, and trend analysis were performed, followed by CV-ANOVA to determine BV estimates and their 95% CIs. These estimates were used to calculate APS and reference change values. For Lp(a), BV estimates were determined on normalized concentration quintiles. RESULTS: Within-subject BV estimates were significantly different between sexes for Lp(a) and between women aged <50 and >50 years for apoA-I and apoB. Lp(a) APS was constant across concentration quintiles and, overall, lower than APS based on currently published data, whereas results were similar for apoA-I and apoB. CONCLUSION: Using a fully Biological Variation Data Critical Appraisal Checklist (BIVAC)-compliant protocol, our study data confirm BV estimates of Lp(a) listed in the European Federation of Clinical Chemistry and Laboratory Medicine database and reinforce concerns expressed in recent articles regarding the suitability of older APS recommendations for Lp(a) measurements. Given the heterogeneity of Lp(a), more BIVAC-compliant studies on large numbers of individuals of different ethnic groups would be desirable.


Assuntos
Apolipoproteína A-I/sangue , Apolipoproteína B-100/sangue , Variação Biológica Individual , Lipoproteína(a)/sangue , Adulto , Idoso , Apolipoproteína A-I/normas , Apolipoproteína B-100/normas , Feminino , Humanos , Lipoproteína(a)/normas , Masculino , Pessoa de Meia-Idade , Valores de Referência , Adulto Jovem
16.
Sci Total Environ ; 713: 136641, 2020 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-32019024

RESUMO

The rapid development of China's fisheries economy is accompanied by intensified marine environmental pollution over the period covered by this study. Based on data from multiple sources, this paper attempts to measure the relationship between fisheries economic growth and marine environmental pollution among China's coastal regions over the past 17 years. For this purpose, it firstly quantifies changes in fisheries economy and fisheries population. It then goes onto comparing the degree of changes in fisheries economy and marine environment. Finally, it depicts the relationship between fisheries added value (FAV) and polluted marine area (PMA) and between per capita net income of fishermen (PCNIF) and PMA ratio. Results suggest that.

17.
Materials (Basel) ; 12(17)2019 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-31443408

RESUMO

The stratospheric airship envelope material is operated in biaxial stress, so it is necessary to study the in-plane biaxial tensile strength. In this paper, a theoretical model is developed to evaluate the mechanical properties of in-plane biaxial specimens. Being applied to the finite element analysis, the theoretical model is employed to evaluate the influence of strengthening material behavior (E*) and geometry parameters on the mechanical behavior in the central. The follows results are drawn: (i) smaller the length of the central region (Lcen), E* and larger the central region corner radius (r) contribute to smaller coefficient of variation (CV); (ii) smaller Lcen and larger E* contribute to smaller stress concentration factor (k), k in the limit state of r is larger than that in other conditions. (iii) The CV and k under stress ratio of 1:1 are smaller than those under other stress ratios. The study can provide a useful reference for the design of biaxial specimens.

18.
Environ Sci Pollut Res Int ; 26(28): 28993-29002, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31388947

RESUMO

The consequence of carcinogenic and non-carcinogenic health risks of the heavy metal concentrations in street dust of North Cyprus is yet to be reported. This study is aimed at investigating the concentration of six different heavy metals' concentration explicitly: As, Cu, Zn, Ni, Cr, and Pb, along leading highways in Nicosia. The result obtained was analyzed using an X-ray fluorescent machine. Multivariate and statistical methods were applied for the data analysis using xlstat MS-excel; furthermore, index of geo-accumulation (Igeo) and human health risk assessment using exposure pathways as defined by United State Environmental Protection Agency (USEPA) pollution mode were also used for level assessment and health risk implications. The average (M ± SD) concentrations of the metals in the dust are as follows: As (17.48 ± 1.53 mg/kg), Cu (51.86 ± 8.60 mg/kg), Cr (321.14 ± 8.20 mg/kg), Pb (35.62 ± 8.54 mg/kg), Ni (64.79 ± 8.72 mg/kg), and Zn (136.13 ± 30.85 mg/kg). Variation coefficient, Vc, and principle component analysis (PCA) suggested that As, Cr, Ni, and Pb have same source of pollution emission from both natural and anthropogenic activities, Zn from traffic emission while Cu from natural source. However, the result was compared with other nearby towns bordering North Cyprus; all the metal shows similar pattern of pollution with the exception of Cr which is 5 and 11 times higher than street dust of Amman (Jordan) and Tokat (Turkey), respectively. Additionally, Igeo result has the following decreasing order: Zn > Cr > Pb > Ni > Cu > As and also revealed that the As, Cu, and Ni have originated from natural source. Cr has mix source: one from traffic and the other one from atmospheric deposition. Also, Pb is emitted from industrial pollution, whereas 80% of Zn are from traffic-related emissions. The non-carcinogenic health risk (hazard quotient (HQ) and hazard index (HI)) follows the order Cr > As>Ni > Pb > Zn > Cu for children and adults. It is found that the HI of As, Cu, Ni, Pb, and Zn is less one; hence, the street dust does not exhibit non-carcinogenic health risk. But that of Cr content is greater than one, with HI values of Cr 1.44E+02 and 1.55E+01 for children and adults, respectively. The result for carcinogenic health risk (total cancer risk (TCR)) has the following order: Pb (1.42E-05) > Cr (4.81E-09) > (Ni 1.35E-09) > As (1.96E-10). With all the values less than threshed hole limit of TCR ≥ 10-4, street dust does not possess carcinogenic health risk for the entire values of six heavy metals considered in this work.


Assuntos
Carcinógenos/análise , Poeira/análise , Poluição Ambiental/análise , Metais Pesados/análise , Adulto , Carcinógenos/química , Criança , Cidades , Chipre , Humanos , Indústrias , Jordânia , Metais Pesados/química , Medição de Risco , Turquia
19.
Artigo em Inglês | MEDLINE | ID: mdl-31387258

RESUMO

In this paper, an improved fuzzy matter-element (IFME) method was proposed, which integrates the classical matter-element (ME) method, set pair analysis (SPA), and variable coefficient method (VCM). The method was applied to evaluate water quality of five monitor stations along Caoqiao River in Yixing city, Jiangsu Province, China. The levels of river water quality were determined according to fuzzy closeness degree. Compared with the traditional evaluation methods, the IFME method has several characteristics as follows: (i) weights were determined by the VCM method, which can reduce workload and overcome the adverse effects of abnormal values, (ii) membership degrees were defined by SPA, which can utilize monitored data more scientifically and comprehensively, and (iii) IFME is more suitable for seriously polluted rivers. Overall, these findings reinforce the notion that an integrated approach is essential for attaining scientific and objective assessment of river water quality.


Assuntos
Monitoramento Ambiental/métodos , Lógica Fuzzy , Rios/química , Poluentes Químicos da Água , Qualidade da Água/normas , China
20.
Clin Interv Aging ; 14: 1265-1276, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31371932

RESUMO

BACKGROUND: Gait measures such as gait speed, stride length, step width, and stance duration change with advanced age and are associated with adverse health outcomes among older adults. The stride-to-stride variabilities of gait measures are also related to falls and cognitive decline in older adults; however, reference values of these gait parameters in older Japanese adults do not exist. This study aimed to determine the reference values of gait parameters as measured by a plantar pressure platform in community-dwelling older Japanese adults. METHODS: Community-dwelling adults (N=1,212) who were independent in basic activities of daily living and aged 70-96 years (491 men, 721 women) completed the gait performance measurement in a geriatric health assessment. We assessed 10 gait performance measures with a plantar pressure platform system (P-WALK, BTS Bioengineering) and calculated means and coefficient of variations (CVs) of the gait measures as well as quintiles for those gait parameters per age group among men and women. RESULTS: Mean (SDs) of gait speed, stride length, step width, and stance durations were 1.26 (0.24) meters per second (m/s), 121.9 (19.8) cm, 24.0 (3.2) cm, and 552.4 (60.4) milliseconds (ms), respectively, in men, and 1.27 (0.21) m/s, 115.7 (16.3) cm, 17.9 (2.8) cm, and 517.6 (59.8) ms, respectively, in women. Mean of CVs (SD) of stride length, step width, and single-stance duration were 2.76 (1.35), 12.06 (3.98), and 5.74 (2.66), respectively, in men and 2.69 (1.24), 15.65 (4.53), and 5.77 (2.40), respectively, in women. Gait parameters (except CVs of step width) declined significantly with age regardless of gender (P< 0.01 for trends). CONCLUSION: This study determined age group dependent gait parameter reference values, presented as means with quintile ranges, in community-dwelling older Japanese adults. These reference values may be useful metrics for gait assessment in the elderly.


Assuntos
Atividades Cotidianas , Vida Independente , Atividade Motora/fisiologia , Velocidade de Caminhada/fisiologia , Acidentes por Quedas/prevenção & controle , Idoso , Idoso de 80 Anos ou mais , Disfunção Cognitiva/diagnóstico , Feminino , Avaliação Geriátrica/métodos , Humanos , Japão , Masculino , Valores de Referência , Características de Residência
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