Characterization of a novel form of progressive retinal atrophy in Whippet dogs: a clinical, electroretinographic, and breeding study.

OBJECTIVE: To describe a form of progressive retinal atrophy (PRA) in Whippets including clinical, electroretinographic, optical coherence tomographic changes and pedigree analysis. ANIMALS STUDIED: Client-owned Whippet dogs (n = 51) living in Brazil. PROCEDURES: All animals were submitted for routine ophthalmic screening for presumed inherited ocular disease, which included the following: visual tests, such as obstacle course tests, in scotopic and photopic conditions, cotton ball test, dazzle reflex, ocular fundus evaluation by indirect ophthalmoscopy followed by fundus photography. Additionally, electroretinography (ERG) and optical coherence tomography (OCT) were performed in 24 and four dogs, respectively. RESULTS: Sixteen dogs were diagnosed with PRA. Vision deficits in dim light were detected in dogs examined at a young age associated with nystagmus. Funduscopic changes included the development of multifocal retinal bullae from 6 months of age. Retinal thinning became apparent later, at which time the bullae were no longer detected. OCT examination of selected young dogs revealed that the retinal bullae were due to separation between photoreceptors and the retinal pigment epithelium, and of dogs with more advanced disease confirmed the development of retinal thinning. Electroretinography in young dogs revealed a negative ERG due to a lack of b-wave in both scotopic and photopic recordings. With progression, the ERG became unrecordable. Pedigree analysis suggested an autosomal recessive mode of inheritance. CONCLUSION: The retinal dystrophy reported here in Whippet dogs has a unique phenotype of an initial lack of ERG b-wave, development of retinal bullae then a progressive generalized retinal degeneration.

iptet / Pulmonary lobar torsion in a Whippet dog

A torção de lobo pulmonar (TLP) consiste na rotação do pulmão, ou de um de seus lobos, ao longo deseu eixo, com consequente torção de brônquios e vasos pulmonares na região do hilo. É considerada umadoença respiratória rara, que acomete cães e gatos. Qualquer fator que aumente a mobilidade pulmonarpode predispor a TLP, incluindo-se as efusões pleurais. Contudo, a TLP também pode ser idiopáticaprincipalmente em cães de grande porte com cavidade torácica profunda, como nas raças Afghan Hounde Whippet, embora a TLP já tenha sido relatado em cães das raças Pug e Jack Russel Terrier. Este trabalhoobjetiva fazer um relato de caso de TLP e uma sucinta revisão de literatura sobre características relevantesda TLP, principalmente de cães. Uma cadela de 10 anos de idade da raça Whippet foi encaminhadapara necropsia no Setor de Patologia da Escola de Veterinária da UFMG, na qual foi observada rotaçãode 180º do lobo pulmonar médio direito. Apesar de ser considerada uma condição rara, a TLP deve serconsiderada no diagnóstico diferencial por clínicos veterinários ao atender animais com sinais clínicosde dispneia.(AU)

Pulmonary lobe torsion (PLT) is the rotation of the lung or one of its lobes along its axis, with consequentobstruction of the bronchi and pulmonary vessels in the hilar region. It is considered a rare respiratorydisease, with few reports in dogs and cats. Any mechanism that increases the mobility of the lungs canpredispose to PLT, including pleural effusions. PLT may also be idiopathic, especially in large dogs withdeep thoracic cavity, such as Afghan Hounds and Whippets. However, it has already been reported insmall breed dogs including Pug and Jack Russell Terrier. This report aims to describe a case report ofPLT, and provide a brief review of the literature including relevant aspects of PLT, especially in dogs.A 10-years-old female Whippet was sent to necropsy at the Pathology Division of the Veterinary Schoolat UFMG, where it was diagnosed with a 180º rotation of the right middle lobe. Although considered arare condition, PLT must be considered in the differential diagnosis by veterinarians facing animals withclinical signs of dyspnea.(AU)

iptet / Pulmonary lobar torsion in a Whippet dog

A torção de lobo pulmonar (TLP) consiste na rotação do pulmão, ou de um de seus lobos, ao longo deseu eixo, com consequente torção de brônquios e vasos pulmonares na região do hilo. É considerada umadoença respiratória rara, que acomete cães e gatos. Qualquer fator que aumente a mobilidade pulmonarpode predispor a TLP, incluindo-se as efusões pleurais. Contudo, a TLP também pode ser idiopáticaprincipalmente em cães de grande porte com cavidade torácica profunda, como nas raças Afghan Hounde Whippet, embora a TLP já tenha sido relatado em cães das raças Pug e Jack Russel Terrier. Este trabalhoobjetiva fazer um relato de caso de TLP e uma sucinta revisão de literatura sobre características relevantesda TLP, principalmente de cães. Uma cadela de 10 anos de idade da raça Whippet foi encaminhadapara necropsia no Setor de Patologia da Escola de Veterinária da UFMG, na qual foi observada rotaçãode 180º do lobo pulmonar médio direito. Apesar de ser considerada uma condição rara, a TLP deve serconsiderada no diagnóstico diferencial por clínicos veterinários ao atender animais com sinais clínicosde dispneia.

Pulmonary lobe torsion (PLT) is the rotation of the lung or one of its lobes along its axis, with consequentobstruction of the bronchi and pulmonary vessels in the hilar region. It is considered a rare respiratorydisease, with few reports in dogs and cats. Any mechanism that increases the mobility of the lungs canpredispose to PLT, including pleural effusions. PLT may also be idiopathic, especially in large dogs withdeep thoracic cavity, such as Afghan Hounds and Whippets. However, it has already been reported insmall breed dogs including Pug and Jack Russell Terrier. This report aims to describe a case report ofPLT, and provide a brief review of the literature including relevant aspects of PLT, especially in dogs.A 10-years-old female Whippet was sent to necropsy at the Pathology Division of the Veterinary Schoolat UFMG, where it was diagnosed with a 180º rotation of the right middle lobe. Although considered arare condition, PLT must be considered in the differential diagnosis by veterinarians facing animals withclinical signs of dyspnea.