The first recorded outbreak of epidemic dropsy, 1877-80: Climate, empire, and colonial medical science between India, Bengal, and Mauritius.

This article reconstructs the first outbreak of epidemic dropsy recorded in documentary evidence, which occurred in Calcutta, Mauritius, and northeastern India and Bengal in 1877-80. It uses current medical knowledge and investigations into the wider historical contexts in which the epidemic occurred to re-read the colonial medical literature of the period. It shows that colonial policies and structures in the context of variable enviro-climatic conditions increased the likelihood that an epidemic would break out, while also increasing the vulnerability of certain populations to infection and mortality. Additionally, it shows how the trans-regional nature of the epidemic contributed to varying understandings of the disease between two colonial medical establishments, which influenced each other in contradictory ways. The article's core contributions are to recent trans-regional perspectives on disease transmission and colonial medical knowledge production in the Indian Ocean World.

(Un)making labor invisible: A syllabus.

From industrial psychology and occupational therapy to the laboratory bench and scenes of "heroic" fieldwork, there are important connections between the science of labor and the labor of science. Participants in the 2022 Gordon Cain Conference explored how greater attention to these connections might deepen historical understanding of what constitutes "science" and what counts as "labor." Our conversations circled around themes of vulnerability (of systems, individual bodies, historical testimony), affect (pertaining to historical actors and ourselves), and interdependence (e.g. across human groups, species, political boundaries, and time). For the members of this group, which grew out of a panel discussion, these themes and motivations coalesced around a topical focus on invisibility, which helped us to articulate - in the form of a co-created syllabus - research questions about science and labor from multiple angles pertaining to practice, archival preservation, and scholarly representation. This syllabus is organized into six thematic modules that aim to challenge and historicize the concept of invisible labor by facilitating comparisons across geographic, temporal, conceptual, and disciplinary boundaries. The goals of this collaborative syllabus, in sum, are manifold: we seek to facilitate more inclusive histories of science through critical engagement with "invisibility" and thereby promote a more expansive understanding of what constitutes scientific labor; to highlight the constitutive role of gendered labor practices in the scientific enterprise; to draw attention to interdependencies that make all forms of production (knowledge or material) possible; to elucidate systems of remuneration for scientific labor over the longue durée and through pointed comparisons; and, finally, to promote self-reflexivity about the methods we use to narrate the history of science and make sense of our own labors.

Colonial rodent control in Tanganyika and the application of ecological frameworks.

ABSTRACTAt the end of the 1920s, Tanganyika Territory experienced several serious rodent outbreaks that threatened cotton and other grain production. At the same time, regular reports of pneumonic and bubonic plague occurred in the northern areas of Tanganyika. These events led the British colonial administration to dispatch several studies into rodent taxonomy and ecology in 1931 to determine the causes of rodent outbreaks and plague disease, and to control future outbreaks. The application of ecological frameworks to the control of rodent outbreaks and plague disease transmission in colonial Tanganyika Territory gradually moved from a view that prioritised 'ecological interrelations' among rodents, fleas and people to one where those interrelations required studies into population dynamics, endemicity and social organisation in order to mitigate pests and pestilence. This shift in Tanganyika anticipated later population ecology approaches on the African continent. Drawing on sources from the Tanzania National Archives, this article offers an important case study of the application of ecological frameworks in a colonial setting that anticipated later global scientific interest in studies of rodent populations and rodent-borne disease ecologies.

The instrumental Brahmin and the "half-caste" computer: Astronomy and colonial rule in Madras, 1791-1835.

What did science make possible for colonial rule? How was science in turn marked by the knowledge and practices of those under colonial rule? Here I approach these questions via the social history of Madras Observatory. Constructed in 1791 by the East India Company, the observatory was to provide local time to mariners and served as a clearinghouse for the company's survey and revenue administration. The astronomical work of Madras' Brahmin assistants relied upon their knowledge of jyotisastra [Sanskrit astronomy/astrology], and can be seen as a specialized form of the kind of South Indian scribal labor and knowledge that also staffed the company's tax offices. If at Greenwich the division of labor meant observatory work bore resemblances to the factory and the accounts office, in Madras, astronomy and accounting drew on similar labor forms because they were part of the same enterprise. But the company did not just adapt preexisting forms of labor, it also attempted to produce its own at a school built near the observatory to train "half-caste" orphans as apprentice surveyors and assistant computers. The school, staffed by the Brahmins, drew upon knowledge and pedagogical practice associated with the tinnai, the schools in which upper-caste children learned to read, write, and calculate. For a time, the observatory's social order was literally "half-caste." The paper also considers how the relationship between caste, status, and instrument was reflected in the visual and material culture of the observatory, such as in Indian-language inscriptions on its central pillar. For company astronomers, the measurement of time meant reworking the relationships among the Indian past, the colonial present, and an imperial posterity. Science under colonial rule spanned multiple temporal and social registers because it was the result of negotiations between the demands of political economy and the knowledge and practices of colonized others.

Handling Ethics Dumping and Neo-Colonial Research: From the Laboratory to the Academic Literature.

This paper explores that the topic of ethics dumping (ED), its causes and potential remedies. In ED, the weaknesses or gaps in ethics policies and systems of lower income countries are intentionally exploited for intellectual or financial gains through research and publishing by higher income countries with a more stringent or complex ethical infrastructure in which such research and publishing practices would not be permitted. Several examples are provided. Possible ED needs to be evaluated before research takes place, and detected prior to publication as an academic paper, because it might lead to a collaborative effort between a wealthier country with restrictive ethical policies and a less wealthy country with more permissive policies. Consequently, if that collaboration ultimately results in an academic paper, there are ethical ramifications of ED to scholarly communication. Institutional review board approval is central to avoid ED-based collaborations. Blind trust and goodwill alone cannot eliminate the exploitation of indigenous or "vulnerable" populations' intellect and resources. Combining community-based participatory research using clear codes of research conduct and a simple but robust verification system in academic publishing may reduce the risks of ED-based research from being published.

Emerging infrastructures: the politics of radium and the validation of radiotherapy in India's first tertiary cancer hospital.

This article traces the history of India's first tertiary cancer hospital, Tata Memorial Hospital (TMH). TMH was originally conceived in 1932 as a philanthropic project by the Tatas, an elite Parsi business family in Bombay. The founding of TMH represented a form of philanthro-capitalism which both enabled the Tatas to foster a communal acceptance for big businesses in Bombay and provide the Tatas with the opportunity to place stakes in the emerging nuclear research economy seen as essential to the scientific nationalist sentiment of the post-colonial state. In doing this, the everyday activities of TMH placed a heavy emphasis on nuclear research. In a time when radium for the treatment of cancer was still seen as 'quackery' in much of the world, the philanthro-capitalist investment and the interest in nuclear research by the post-colonial state provided an environment where radium medicine was able to be validated. The validation of radiotherapy at TMH influenced how other cancer hospitals in India developed and also provided significant resources for cancer research in early-mid twentieth century India. Ultimately, this article identifies ways in which cancer comes to be seen as relevant in the global south and raises questions on the relationship between local and global actors in setting health priorities.

A mestizo cosmographer in the New Kingdom of Granada: astronomy and chronology in Sánchez de Cozar Guanientá's Tratado (c.1696).

This article interprets a recently recovered manuscript, Tratado de astronomía y la reformaçión del tiempo, composed by Antonio Sánchez in New Granada c.1696, in the context of the Spanish and Renaissance cosmographies. Sánchez's Tratado proposes a spherical astronomy, in which celestial bodies - including comets - move in orbs containing pyramidal knots that explain the changing speed observed in the motion of planets. From this astronomy and following the peninsular style of repertorios, Sánchez derives two major conclusions: the corrected length of the solar year and a revised birth date of Jesus. Taking as center of reference Vélez, where Sánchez was based, these claims led to conclusions in domains ranging from calendric astronomy to eschatology, including the incorporation of the indigenous peoples into salvation narrative and a demonstration of the arrangement of the celestial orbs at the Last Judgment. Sánchez's Tratado constitutes an expansion of the Spanish mathematical cosmography that sheds light on the production of knowledge in the Spanish-American world and, at the same time, provides elements to reassess our understanding of the global circulation of Renaissance and early modern ideas.

Plantation Botany: Slavery and the Infrastructure of Government Science in the St. Vincent Botanic Garden, 1765-1820 s*.

This essay examines the aims, labor regime, and workers of the St. Vincent botanic garden to highlight differences in the infrastructure of government-funded botany across the British empire. It argues that slavery was a foundational element of society and natural history in the Anglo-Caribbean, and the St. Vincent botanic garden was both put into the service of slavery and transformed by it. When viewed from the Caribbean context and the perspective of enslaved workers, the St. Vincent garden's affiliation with imperial improvement becomes less salient than its support of the status quo of slavery as a system and labor regime. The garden was dependent on enslaved laborers, yet the conditions of work and contemporary prejudices led superintendents to see them as undifferentiated labor. The politics of the archive make it impossible for historians to reconstruct the experiences of the garden's enslaved workers as individuals, including the specific labor that they performed or skills that they possessed. Plantation slavery's appropriation of and influence on the infrastructure of colonial botany through the St. Vincent botanic garden suggests that historians should center the local logics of the societies where scientific knowledge making took place to reveal the many meanings of science.

Newtonian medicine and its influence in José Celestino Mutis's General Plan for Medical Studies.

This paper presents the development of a Newtonian approach to medicine in the eighteenth century by studying the case of its appropriation in the Viceroyalty of New Granada by the Spanish botanist and savant José Celestino Mutis (1732-1808). First, I briefly depict the academic milieu in which Mutis presented his ideas on modern medicine in his General Plan for the Medical Studies in 1804, claiming that they were greatly influenced by Boerhaave's appropriation of Newtonian medicine. Next, I explain in detail the emergence of this approach to medicine by considering the works of Archibald Pitcairne, George Cheyne and James Keill. Afterwards, I characterise Boerhaave's use of Newtonian physical principles for explaining both physiological and chemical phenomena. Lastly, I lay the foundations for explaining that Mutis's introduction of Newton's ideas was a complex enterprise, encompassing Newton's mathematics and physics not only as strict theoretical elements related to natural philosophy but also as they were related to the medical and chemical fields.

The most perfect natural laboratory in the world: Making and knowing Hawaii National Park.

This article reimagines the meanings of U.S. national parks and so-called 'natural' places in our environmental histories and histories of science. Environmental historians have created a compelling narrative about the creation and use of U.S. national parks as places for recreation and natural resource conservation. Although these motivations were undoubtedly significant, I argue that some of the early parks were created and used for a third, often overlooked, reason: to preserve a permanent, state-sanctioned space for scientific knowledge production. Deconstructing the concept of the "natural laboratory," I show how scientists helped justify and then benefited from the creation of national parks. Hawaii National Park serves as my case study. Advocates of the national park aimed to give settler colonial scientists in the Hawaiian archipelago a permanent place for their research, while tying Hawai'i's exotic landscape into the sublime nature of the American West. The park was framed as a perfect laboratory for U.S. experts to study "curious" flora, fauna, and geological processes, becoming a major site of knowledge production in volcanology. Reimagining the parks in this way has ramifications for how we think about issues of access and justice. Environmental historians who have explored the 'dark side' of the conservation movement have yet to consider the other half of the story: the parks not only barred certain peoples and their ways of life, but also provided access to scientists - a set of actors whose work was deemed more complementary to conservationist goals than the activities of the Native Hawaiians - and marginalized local and indigenous epistemologies. Thus, the question so often asked in environmental history, "Who is nature for?" might be supplemented by the question, "Who has the power to know nature?"

José Celestino Mutis' appropriation of Newton's experimental physics in New Granada (1761-1808).

This paper characterizes José Celestino Mutis' (1732-1808) appropriation of Newton in the Viceroyalty of New Granada. First, we examine critically traditional accounts of Mutis' works highlighting, on the one hand, their inadequacy for directing their claims toward the nineteenth-century independence from Spain and, on the other, for not differentiating between Newtonianism and Enlightenment. Next, we portray Mutis' complex Newtonianism from his own statements and from printed sources, including a variety of works and translations from British, Dutch, and French authors, in addition to a wide range of Newton's writings, unusual for an eighteenth-century reader in the Americas. Finally, we analyze a salient claim of Mutis' Newtonianism in order to depict his appropriation and transformation of Newton's ideas: the characterization of Newtonian experimental physics as a useful science. In so doing, Mutis further developed metaphysical and methodological positions not present in Newton's works.

Laboratory of domesticity: Gender, race, and science at the Bermuda Biological Station for Research, 1903-30.

During the early twentieth century, the Bermuda Biological Station for Research (BBSR) functioned as a multipurpose scientific site. Jointly founded by New York University, Harvard University, and the Bermuda Natural History Society, the BBSR created opportunities for a mostly US-based set of practitioners to study animal biology in the field. I argue that mixed gender field stations like the BBSR supported professional advancement in science, while also operating as important places for women and men to experiment with the social and cultural work of identity formation, courtship and marriage, and social critique. Between 1903 and 1930, the BBSR functioned as a laboratory of domesticity, a temporary scientific household in British Bermuda where women and men interacted with established colonial ideologies about science, sex difference, and racial hierarchy in their public and private accounts of doing biology and socializing in the field. Viewing field stations as generative of multiple forms of labor offers a corrective to narratives within the history of biology, in which scientific practices are considered to be the principal forms of output produced by practitioners in the field. Understanding how women and men at the BBSR engaged with (and at times critiqued) the politics of gender and race from the periphery of U.S. networks of biology suggests that we might view field stations as shaping not only academic science but also domestic life and fields as disparate as fiction and the law.

Field station as stage: Re-enacting scientific work and life in Amani, Tanzania.

Located high in Tanzania's Usambara Mountains, Amani Hill Station has been a site of progressive scientific endeavours for over a century, pushing the boundaries of botanical, zoological and medical knowledge, and providing expertise for imperial expansion, colonial welfare, national progress and international development efforts. The station's heyday was from the 1950s to the 1970s, a period of global disease eradication campaigns and the 'Africanization' of science. Today, Amani lies in a state of suspended motion. Officially part of a national network of medical research stations, its buildings and vegetation are only minimally maintained, and although some staff report for duty, scientific work has ceased. Neither ruin nor time capsule, Amani has become a quiet site of remains and material traces. This article examines the methodological potentials of re-enactment - on-site performances of past research practices - to engage ethnographically with the distinct temporalities and affective registers of life at the station. The heuristic power of re-enactment resides in its anachronicity, the tensions it introduces between immediacy and theatricality, authenticity and artifice, fidelity and futility. We suggest that re-enacting early post-colonial science as events unfolding in the present disrupts straightforward narratives about the promises and shortfalls of scientific progress, raising provocative questions about the sentiments and stakes of research in 'the tropics'.

Postcolonial Ecologies of Parasite and Host: Making Parasitism Cosmopolitan.

The interest of F. Macfarlane Burnet in host-parasite interactions grew through the 1920s and 1930s, culminating in his book, Biological Aspects of Infectious Disease (1940), often regarded as the founding text of disease ecology. Our knowledge of the influences on Burnet's ecological thinking is still incomplete. Burnet later attributed much of his conceptual development to his reading of British theoretical biology, especially the work of Julian Huxley and Charles Elton, and regretted he did not study Theobald Smith's Parasitism and Disease (1934) until after he had formulated his ideas. Scholars also have adduced Burnet's fascination with natural history and the clinical and public health demands on his research effort, among other influences. I want to consider here additional contributions to Burnet's ecological thinking, focusing on his intellectual milieu, placing his research in a settler society with exceptional expertise in environmental studies and pest management. In part, an ''ecological turn'' in Australian science in the 1930s, derived to a degree from British colonial scientific investments, shaped Burnet's conceptual development. This raises the question of whether we might characterize, in postcolonial fashion, disease ecology, and other studies of parasitism, as successful settler colonial or dominion science.

Making blood 'Melanesian': fieldwork and isolating techniques in genetic epidemiology (1963-1976).

'Isolated' populations did not exist unproblematically for life scientists to study. This article examines the practical and conceptual labour, and the historical contingencies that rendered populations legible as 'isolates' for population geneticists. Though a standard historiographical narrative tells us that population geneticists were moving from typological understandings of biological variation to processual ones, cultural variation was understood as vulnerable to homogenisation. I chart the importance that D. Carleton Gajdusek placed on isolates from his promotion of genetic epidemiology in WHO technical reports and at a Cold Spring Harbour symposium to his fieldwork routines and collection practices in a group of South Pacific islands. His fieldwork techniques combined social, cultural and historical knowledge of the research subjects in order to isolate biological descent using genealogies. Having isolated a population, Gajdusek incorporated biological materials derived from that population into broad categories of 'Melanesian' and 'race' to generate statements about the genetics of abnormal haemoglobins and malaria. Alongside an analysis of Gajdusek's practices, I present different narratives of descent, kinship and identities learned during my ethnographic work in Vanuatu. These alternatives show tacit decisions made pertaining to scale in the production of 'isolates'.