Intratarsal Keratinous Cyst Clinically Misdiagnosed as a Chalazion.

The intratarsal keratinous cyst (IKC) is a recently described entity, often clinically misdiagnosed as a chalazion. We report a case of a 61-year-old male patient with a chief complaint of a small lesion on the upper eyelid that evolved over six months. On physical examination, an asymptomatic, firm nodule was identified on the left upper eyelid. The patient reported no history of trauma. A provisional diagnosis of chalazion was established, and an excisional biopsy was performed. Histopathologically, the lesion was lined with a stratified squamous epithelium, with a corrugated epithelial surface showing abrupt keratinization without keratohyalin granules, and compact keratinous-appearing material in the cystic lumen. The diagnosis was IKC. No signs of recurrence were observed after one year of follow-up. It is essential to accurately diagnose IKC and distinguish it from chalazion and epidermal inclusion cysts, because IKC requires complete surgical excision and can exhibit multiple recurrences if not properly removed.

Atrophic violaceous plaques as the first manifestation of a disorder of GNAS inactivation.

We report the case of a 10-month-old girl who presented with failure to thrive and multiple small atrophic violaceous plaques, with no other findings on her physical examination. The laboratory examinations, abdominal ultrasound and bilateral hand radiography performed were unremarkable. The skin biopsy revealed fusiform cells and focal ossification in the deep dermis. The genetic study showed a pathogenic variant of GNAS.

Histopathological survey of free-ranging neotropical bats with dermatitis.

Bats have a fundamental ecological role, and no wildlife disease has decimated more individuals than white-nose syndrome (WNS). This impactful mycosis has raised the importance of monitoring disease threats to bat populations. In this study, we aimed to investigate gross skin lesions in neotropical bats by histopathology to survey the occurrence of dermatitis that could resemble WNS cases in Brazil. Eleven species of free-ranging bats were sampled from the rabies surveillance program in 9 municipalities of Northern Paraná. Members of the Molossidae family were the most frequent ones among the 126 analyzed individuals, and 4 cases of dermatitis in 2 black mastiff bats (Molossus rufus), 1 great fruit-eating bat (Artibeus lituratus), and a big free-tailed bat (Nyctinomops macrotis) were detected. Gross lesions included alopecia, macules, discoloration, and hyperkeratosis. Among the bats with gross lesions, dermal thickening and mild inflammation were observed histologically. Two M. rufus bats had dermal fungal invasion; however, none resembled WNS.

Cutaneous apocrine adenocarcinoma in a goat

Apocrine neoplasms are rare in goats. This report describes an apocrine adenocarcinoma in a 5-year-old female Boer goat with an ulcerated, exophytic, multilobulated mass on the left dorsolateral cervical area. Histologically, the dermis was effaced and expanded by a poorly demarcated epithelial neoplasm with desmoplasia. Neoplastic cells were arranged in acini with papillary projections into the lumen and had cuboidal or columnar, eosinophilic, occasionally vacuolated cytoplasm. Nuclei were round and had finely stippled chromatin with one nucleolus. Neoplastic cells contained periodic acid-Schiff (PAS)­positive and diastase­resistant, alcian blue­positive cytoplasmic granules. There were 6 mitoses in 2.37 mm2 (equivalent to 10 FN22/40X fields). Histologic and histochemical features in the current case were consistent with a cutaneous apocrine gland adenocarcinoma.(AU)

Warty Dyskeratoma with involvement of multiple hair follicles in a dog

The warty dyskeratoma is a neoplasm of follicular origin, with uncommon incidence in veterinary medicine, and benign biological behavior. An excisional biopsy sample was received from a dog, female, Shih Tzu, 12 years old, from the left axillary region. Grossly, after section, green and friable multifocal areas were identified, streaked by solid white areas. Microscopically, the analysis revealed multifocal cystic structures, lined by stratified epithelium, with basal area including villous epithelial projections, toward the dermis, and the luminal region featured acantholysis and dyskeratosis, as well as parakeratosis. Those findings were compatible with a warty dyskeratoma affecting multiple hair follicles, thus being the first case report in veterinary medicine with such this unique pattern. Up to now, the literature encompassed only human medicine. This report, besides collaborating to the description of a rare presentation of an uncommon neoplasm, also contributes with new information found for epidemiological studies of this tumor.(AU)

Bullous Melanoma: should the thickness of the bullous lesion be included in Breslow depth measurement?

Abstract Bullous melanoma represents a rare variant of melanoma, especially in patients without underlying bullous cutaneous disease. Few cases have been described in the literature, including cases of melanoma in patients with bullous epidermolysis or Hailey-Hailey disease. The histopathological diagnosis of bullous melanoma does not show any difficulties, except for the measurement of the Breslow index. The rarity of this case, the dilemma of how to measure the Breslow index and the importance of an early diagnosis motivated this report.

Bullous Melanoma: should the thickness of the bullous lesion be included in Breslow depth measurement?

Bullous melanoma represents a rare variant of melanoma, especially in patients without underlying bullous cutaneous disease. Few cases have been described in the literature, including cases of melanoma in patients with bullous epidermolysis or Hailey-Hailey disease. The histopathological diagnosis of bullous melanoma does not show any difficulties, except for the measurement of the Breslow index. The rarity of this case, the dilemma of how to measure the Breslow index and the importance of an early diagnosis motivated this report.

Pseudoxanthoma Elasticum: Report of Two Cases.

Elastic pseudoxanthoma is a rare disease with autosomal recessive inheritance, also known as Grönblad-Strandberg syndrome, characterized by pathological mineralization of the elastic fibers in the connective tissue, affecting principally the dermis of skin, media, and intima of blood vessels and Bruch's membrane of the eye. The genetic defect of the disorder is located on chromosome 16p13.1 and disease is caused by the lack of functional ABCC6 protein, which in turn causes extracellular accumulation and deposition of calcium and other minerals in the elastic tissue. In this article we present two cases of this rare disease. We emphasize, in the diagnostic criteria, the importance of its early diagnosis and the current therapeutic approaches.

Canine cutaneous neoplasms in the metropolitan region of Goiânia, Goiás state, Brazil / Neoplasias cutâneas caninas na região metropolitana de Goiânia, Goiás, Brasil

The present study aimed to describe the occurrence and epidemiological features of skin neoplasms diagnosed in dogs in the metropolitan region of Goiânia, Goiás state, Brazil. Diagnoses from dog biopsies from 2011 to 2016 provided by a private veterinary pathology laboratory were analyzed. The main diagnoses were mast cell tumor, hemangiosarcoma, squamous cell carcinoma, malignant melanoma, and hemangioma. Highest frequency of neoplasms was found in female dogs, dogs aged > 8 years, and purebred dogs, particularly the American Pit Bull Terriers and the Poodles. Most common sites affected by the neoplasms were the limb and the head. Using multiple correspondence analysis, groups of neoplasms were found to be associated with different epidemiological features and the size of the neoplasms was associated with the biological behavior. The results of this study described predispositions and verified the importance of different types of skin neoplasms in dogs in the region being studied.(AU)

O objetivo deste estudo foi determinar a prevalência e as características epidemiológicas das neoplasias cutâneas em cães na região metropolitana de Goiânia, Goiás. Foram analisados os diagnósticos de um laboratório do setor privado de 2011 a 2016. Mastocitoma, hemangiossarcoma, carcinoma de células escamosas, melanoma maligno e hemangioma representaram os principais diagnósticos. A maioria dos casos ocorreram em cães de raças definidas, fêmeas e com idade >8 anos. American Pit Bull Terrier e Poodle foram as raças mais encontradas. As neoplasias acometeram principalmente regiões de membros e cabeça. Pela análise de correspondência múltipla, associou-se os grupos de neoplasias com diferentes características epidemiológicas e o tamanho da neoplasia com o comportamento biológico. A comparação dos resultados com pesquisas prévias possibilitou confirmar predisposições previamente descritas e verificar a importância dos diferentes tipos de neoplasias cutâneas em cães na região estudada.(AU)

Canine cutaneous neoplasms in the metropolitan region of Goiânia, Goiás state, Brazil / Neoplasias cutâneas caninas na região metropolitana de Goiânia, Goiás, Brasil

ABSTRACT: The present study aimed to describe the occurrence and epidemiological features of skin neoplasms diagnosed in dogs in the metropolitan region of Goiânia, Goiás state, Brazil. Diagnoses from dog biopsies from 2011 to 2016 provided by a private veterinary pathology laboratory were analyzed. The main diagnoses were mast cell tumor, hemangiosarcoma, squamous cell carcinoma, malignant melanoma, and hemangioma. Highest frequency of neoplasms was found in female dogs, dogs aged > 8 years, and purebred dogs, particularly the American Pit Bull Terriers and the Poodles. Most common sites affected by the neoplasms were the limb and the head. Using multiple correspondence analysis, groups of neoplasms were found to be associated with different epidemiological features and the size of the neoplasms was associated with the biological behavior. The results of this study described predispositions and verified the importance of different types of skin neoplasms in dogs in the region being studied.(AU)

O objetivo deste estudo foi determinar a prevalência e as características epidemiológicas das neoplasias cutâneas em cães na região metropolitana de Goiânia, Goiás. Foram analisados os diagnósticos de um laboratório do setor privado de 2011 a 2016. Mastocitoma, hemangiossarcoma, carcinoma de células escamosas, melanoma maligno e hemangioma representaram os principais diagnósticos. A maioria dos casos ocorreram em cães de raças definidas, fêmeas e com idade >8 anos. American Pit Bull Terrier e Poodle foram as raças mais encontradas. As neoplasias acometeram principalmente regiões de membros e cabeça. Pela análise de correspondência múltipla, associou-se os grupos de neoplasias com diferentes características epidemiológicas e o tamanho da neoplasia com o comportamento biológico. A comparação dos resultados com pesquisas prévias possibilitou confirmar predisposições previamente descritas e verificar a importância dos diferentes tipos de neoplasias cutâneas em cães na região estudada.(AU)

Ulcerative dermatitis due to feline infectious peritonitis virus infection in a cat

Feline infectious peritonitis (FIP) is one of the most prevalent viral diseases of wild and domestic cats. Despite of its multisystemic character, cutaneous lesions of FIP have been rarely described. A skin biopsy from a 14-month-old maleneutered domestic shorthaired cat with a slightly raised, 5 mm in diameter ulcer on the dorsal cervical area and apresumptive clinical diagnosis of FIP was submitted for histological examination. Histological changes consisted of ulcerative dermatitis with perivascular, periadnexal, and interstitial accumulations of neutrophils, macrophages, lymphocytes, and plasma cells with areas of vasculitis. Immunohistochemistry for feline coronavirus revealed intralesional clusters of antigen within macrophages. FIP should be considered in cases of papular to nodular or ulcerative skin lesions in cats when occurring in conjunction with clinical signs of systemic disease consistent with FIP.(AU)

Ulcerative dermatitis due to feline infectious peritonitis virus infection in a cat

Feline infectious peritonitis (FIP) is one of the most prevalent viral diseases of wild and domestic cats. Despite of its multisystemic character, cutaneous lesions of FIP have been rarely described. A skin biopsy from a 14-month-old maleneutered domestic shorthaired cat with a slightly raised, 5 mm in diameter ulcer on the dorsal cervical area and apresumptive clinical diagnosis of FIP was submitted for histological examination. Histological changes consisted of ulcerative dermatitis with perivascular, periadnexal, and interstitial accumulations of neutrophils, macrophages, lymphocytes, and plasma cells with areas of vasculitis. Immunohistochemistry for feline coronavirus revealed intralesional clusters of antigen within macrophages. FIP should be considered in cases of papular to nodular or ulcerative skin lesions in cats when occurring in conjunction with clinical signs of systemic disease consistent with FIP.

Aspectos anatomopatológicos do linfoma cutâneo em cães revisão / Anatomopathological aspects of cutaneous lymphoma in dogs review / Características histopatológicas del linfoma cutáneo en perros revisión

O linfoma é um dos tipos de câncer mais prevalentes em cães, no entanto, aspectos macroscópicos, de lesões superficiais eritematosas e esfoliativas a tumores. é incomum na pele. Quando se origina na pele, tem sido observado sob vários Histologicamente, os linfomas cutâneos são subdivididos em epiteliotrópicos. Os linfomas epiteliotrópicos geralmente são vistos como micose fungoide e, mais raramente, como reticulose pagetoide ou síndrome de Sézary. Os linfomas não epiteliotrópicos incluem: linfoma anaplásico de grandes células T, linfoma de células T periféricas inespecífico, granulomatose linfomatoide, linfoma intravascular e linfoma de células T semelhante a paniculite subcutânea. Esta revisão de literatura apresenta os aspectos macroscópicos e histopatológicos dos linfomas cutâneos caninos.(AU)

Lymphoma is one of the most prevalent forms of cancers in dogs, however, it is uncommon on the skin. Cutaneous lymphoma can present as erythematous and exfoliative superficial lesions or raised masses. Histologically, cutaneous lymphomas are subdivided into epitheliotropic and non-epitheliotropic. Epitheliotropic lymphomas is mostly seen as mycosis fungoides and more rarely as pagetoid reticulosis or Sézary syndrome. Non-epitheliotropic lymphomas include anaplastic large T-cell lymphoma, unspecified peripheral T-cell lymphoma, lymphomatoid granulomatosis, intravascular lymphoma, and subcutaneous panniculitis-like T-cell lymphoma. This literature review presents macroscopic and histopathological aspects of canine cutaneous lymphomas.(AU)

El linfoma representa uno de los tipos de cáncer más prevalentes en perros, si bien su manifestación dérmica es poco frecuente. Los linfomas de piel pueden presentarse como lesiones superficiales eritematosas y exfoliativas, o bien como tumores. Desde el punto de vista histológico pueden ser clasificados como epiteliotrópicos y no epiteliotrópicos. Los primeros suelen ser vistos como micosis fúngica y, más raro, como reticulosis pagetoide o Síndrome de Sézary. Los linfomas no epiteliotrópicos incluyen el linfoma anaplásico de células T gigantes, linfoma inespecífico de células T, granulomatosis linfomatoide, linfoma intravascular y linfoma de células T similar a paniculitis subcutánea. Esta revisión de literatura presenta aspectos macroscópicos e histopatológicos de los linfomas cutáneos del perro.(AU)

Black hair follicular dysplasia in a fox paulistinha dog: clinical and histopathological features / Displasia folicular do pelo preto em um cão Fox paulistinha–características clínicas e histopatológicas

Black hair follicular dysplasia (BHFD) is an unusual canine skin disorder defined as alopecia confined to black regions of the hair coat. First clinical abnormalities are usually noted around four weeks of age and comprise fracture of hair shafts in black-coated regions, later resulting in partial alopecia, usually, on the head, ear pinnae, neck, and back, whereas some nonblack-coated areas may exhibit normal hair. The diagnosis is confirmed by histopathologic features. This article aims to report a case of black hair follicular dysplasia in a seven-month-old Fox Paulistinha male dog showing alopecia restricted to black-haired areas, in which diagnosis was confirmed by histopathological exams that showed follicular dysplasia associated with melanic accumulation in the hair shaft and in and deep dermal tissue.

A displasia folicular do cabelo preto (BHFD) é uma doença incomum da pele canina definida como alopecia confinada a regiões de pelo preto. As primeiras anormalidades clínicas são geralmente notadas em torno de quatro semanas de idade e compreendem fratura dos pelos em regiões cobertas de pelagem preta, resultando posteriormente em alopecia parcial, geralmente, na cabeça, orelha, pescoço e dorso, enquanto algumas áreas cobertas por pelos que não são pretos, podem ser normais. O diagnóstico é confirmado por características histopatológicas. Este artigo tem como objetivo relatar um caso de displasia folicular do pelo preto em um cão macho Fox Paulistinha de sete meses de idade mostrando alopecia restrita a áreas de pelos pretos, em que o diagnóstico foi confirmado por exames histopatológicos que mostraram displasia folicular associada ao acúmulo melânico no folículo piloso e no tecido dérmico profundo.(AU)

Black hair follicular dysplasia in a fox paulistinha dog: clinical and histopathological features / Displasia folicular do pelo preto em um cão Fox paulistinha–características clínicas e histopatológicas

Black hair follicular dysplasia (BHFD) is an unusual canine skin disorder defined as alopecia confined to black regions of the hair coat. First clinical abnormalities are usually noted around four weeks of age and comprise fracture of hair shafts in black-coated regions, later resulting in partial alopecia, usually, on the head, ear pinnae, neck, and back, whereas some nonblack-coated areas may exhibit normal hair. The diagnosis is confirmed by histopathologic features. This article aims to report a case of black hair follicular dysplasia in a seven-month-old Fox Paulistinha male dog showing alopecia restricted to black-haired areas, in which diagnosis was confirmed by histopathological exams that showed follicular dysplasia associated with melanic accumulation in the hair shaft and in and deep dermal tissue.

A displasia folicular do cabelo preto (BHFD) é uma doença incomum da pele canina definida como alopecia confinada a regiões de pelo preto. As primeiras anormalidades clínicas são geralmente notadas em torno de quatro semanas de idade e compreendem fratura dos pelos em regiões cobertas de pelagem preta, resultando posteriormente em alopecia parcial, geralmente, na cabeça, orelha, pescoço e dorso, enquanto algumas áreas cobertas por pelos que não são pretos, podem ser normais. O diagnóstico é confirmado por características histopatológicas. Este artigo tem como objetivo relatar um caso de displasia folicular do pelo preto em um cão macho Fox Paulistinha de sete meses de idade mostrando alopecia restrita a áreas de pelos pretos, em que o diagnóstico foi confirmado por exames histopatológicos que mostraram displasia folicular associada ao acúmulo melânico no folículo piloso e no tecido dérmico profundo.

Aspectos anatomopatológicos do linfoma cutâneo em cães – revisão / Anatomopathological aspects of cutaneous lymphoma in dogs – review / Características histopatológicas del linfoma cutáneo en perros – revisión

O linfoma é um dos tipos de câncer mais prevalentes em cães, no entanto, aspectos macroscópicos, de lesões superficiais eritematosas e esfoliativas a tumores. é incomum na pele. Quando se origina na pele, tem sido observado sob vários Histologicamente, os linfomas cutâneos são subdivididos em epiteliotrópicos. Os linfomas epiteliotrópicos geralmente são vistos como micose fungoide e, mais raramente, como reticulose pagetoide ou síndrome de Sézary. Os linfomas não epiteliotrópicos incluem: linfoma anaplásico de grandes células T, linfoma de células T periféricas inespecífico, granulomatose linfomatoide, linfoma intravascular e linfoma de células T semelhante a paniculite subcutânea. Esta revisão de literatura apresenta os aspectos macroscópicos e histopatológicos dos linfomas cutâneos caninos.

Lymphoma is one of the most prevalent forms of cancers in dogs, however, it is uncommon on the skin. Cutaneous lymphoma can present as erythematous and exfoliative superficial lesions or raised masses. Histologically, cutaneous lymphomas are subdivided into epitheliotropic and non-epitheliotropic. Epitheliotropic lymphomas is mostly seen as mycosis fungoides and more rarely as pagetoid reticulosis or Sézary syndrome. Non-epitheliotropic lymphomas include anaplastic large T-cell lymphoma, unspecified peripheral T-cell lymphoma, lymphomatoid granulomatosis, intravascular lymphoma, and subcutaneous panniculitis-like T-cell lymphoma. This literature review presents macroscopic and histopathological aspects of canine cutaneous lymphomas.

El linfoma representa uno de los tipos de cáncer más prevalentes en perros, si bien su manifestación dérmica es poco frecuente. Los linfomas de piel pueden presentarse como lesiones superficiales eritematosas y exfoliativas, o bien como tumores. Desde el punto de vista histológico pueden ser clasificados como epiteliotrópicos y no epiteliotrópicos. Los primeros suelen ser vistos como micosis fúngica y, más raro, como reticulosis pagetoide o Síndrome de Sézary. Los linfomas no epiteliotrópicos incluyen el linfoma anaplásico de células T gigantes, linfoma inespecífico de células T, granulomatosis linfomatoide, linfoma intravascular y linfoma de células T similar a paniculitis subcutánea. Esta revisión de literatura presenta aspectos macroscópicos e histopatológicos de los linfomas cutáneos del perro.

Tricofoliculoma em felino: relato de caso / Trichofolliculoma in feline: case report / Tricofoliculoma en felino: reporte de un caso

Os tricofoliculomas são nódulos dérmicos bem circunscritos, desencapsulados, compostos por um ou vários folículos primários, grandes e dilatados, que queratinizam sobre a camada granular, sendo um achado raro na espécie felina. Este relato aborda o caso de um felino macho, castrado, sem raça definida, de pelagem preta, com 11 anos e 5 meses, o qual foi atendido em uma clínica veterinária particular apresentando múltiplos nódulos cutâneos. Foram identificados seis nódulos distribuídos em algumas áreas do corpo, onde cinco destes apresentavam tamanhos semelhantes com aproximadamente 1,5 cm, enquanto o nódulo do membro anterior media cerca de 4 cm de diâmetro e encontrava-se pedunculado. O paciente foi submetido a exames pré-operatórios e encaminhado à exérese dos nódulos onde foram seguidas as recomendações padrões de margem segura durante a cirurgia. O material obtido foi formolizado à 10% e encaminhado ao laboratório de Patologia na Clínica escola de Medicina Veterinária do Centro Universitário Cesmac em marechal Deodoro, Alagoas, onde foi processado. Na análise, foi constatado que se tratava de um tricofoliculoma em virtude da descrição morfológica, revelando múltiplos lóbulos foliculares, com proliferação de células da bainha epitelial e centralmente apresentando lâminas concêntricas de queratina e revestidos por uma espessa e proeminente membrana basal, O paciente apresentou uma excelente recuperação cirúrgica e permaneceu sendo acompanhado semestralmente sem recidivas e com estado geral satisfatório.(AU)

Trichofolliculomas are well circumscribed, decapsulated dermal nodules composed of one or several large, dilated primary follicles that keratinize on the granular layer, being a rare finding in the feline species. This report addresses the case of a male, castrated, undefined, black coat, 11 years and 5 months old, which was attended at a private veterinary clinic with multiple cutaneous nodules. Six nodules distributed in some areas of the body were identified, where five of these had similar sizes of approximately 1.5 cm, while the anterior limb was about 4 cm in diameter and pedunculated. The patient underwent preoperative exams and was submitted to nodule excision where standard recommendations for safe margin were followed during surgery. The material obtained was 10% formolized and sent to the pathology laboratory at the Clinic School of Veterinary Medicine ofthe Centro Universitário Cesmac in Marechal Deodoro, Alagoas, where it was processed. In the analysis, it was verified that it was a trichofolliculoma because of the morphological description, revealing multiple follicular lobes, with proliferation of epithelial sheath cells and centrally presenting concentric sheets of keratin and coated by a thick and prominent basement membrane. The patient presented an excellent surgical recovery and remained accompanied half-yearly without relapses and with satisfactory general condition.(AU)

Los tricofoliculomas son nódulos dérmicos decapsulados bien circunscritos, compuestos de unoo varios folículos primarios grandes y dilatados que se queratinizan en Ia capa granular, siendo un hallazgo raro en las especies felinas. Este informe aborda el caso de un varón felino castrado, indefinido, pelaje negro, de 11anos y 5 meses de edad, que fue atendido en una clínica veterinaria privada con múltiples nódulos cutáneos. Se identificaron seis nódulos distribuidos en algunas áreas del cuerpo, donde cinco de estos tenían tamaños similares de aproximadamente 1.5 cm, mientras que la extremidad anterior tenía unos 4 cm de diámetro y pedunculada. EI paciente se sometió a exámenes preoperatorios y fue sometido a una extirpación de nódulo donde se siguieron las recomendaciones estándar para un margen seguro durante la cirugía. El material obtenidose formolizó ai 1.0% y se envió ai laboratorio de patología de la Escuela Clínica de Medicina Veterinaria del Centro Universitario Cesmac en Marechal Deodoro, Alagoas, donde se procesó. En el análisis, se verificó que se trataba de un tricofoliculoma debido a la descripción morfológica, que revela múltiples lóbulos foliculares, con proliferación de células epiteliales de la vaina y láminas concéntricas de queratina que se presentan centralmente y recubiertas por una membrana basal gruesa y prominente. El paciente presentó una excelente recuperación quirúrgica y permaneció acompariado semestralmente sin recaídas y con un estado general satisfactorio.(AU)

Tricofoliculoma em felino: relato de caso / Trichofolliculoma in feline: case report / Tricofoliculoma en felino: reporte de un caso

Os tricofoliculomas são nódulos dérmicos bem circunscritos, desencapsulados, compostos por um ou vários folículos primários, grandes e dilatados, que queratinizam sobre a camada granular, sendo um achado raro na espécie felina. Este relato aborda o caso de um felino macho, castrado, sem raça definida, de pelagem preta, com 11 anos e 5 meses, o qual foi atendido em uma clínica veterinária particular apresentando múltiplos nódulos cutâneos. Foram identificados seis nódulos distribuídos em algumas áreas do corpo, onde cinco destes apresentavam tamanhos semelhantes com aproximadamente 1,5 cm, enquanto o nódulo do membro anterior media cerca de 4 cm de diâmetro e encontrava-se pedunculado. O paciente foi submetido a exames pré-operatórios e encaminhado à exérese dos nódulos onde foram seguidas as recomendações padrões de margem segura durante a cirurgia. O material obtido foi formolizado à 10% e encaminhado ao laboratório de Patologia na Clínica escola de Medicina Veterinária do Centro Universitário Cesmac em marechal Deodoro, Alagoas, onde foi processado. Na análise, foi constatado que se tratava de um tricofoliculoma em virtude da descrição morfológica, revelando múltiplos lóbulos foliculares, com proliferação de células da bainha epitelial e centralmente apresentando lâminas concêntricas de queratina e revestidos por uma espessa e proeminente membrana basal, O paciente apresentou uma excelente recuperação cirúrgica e permaneceu sendo acompanhado semestralmente sem recidivas e com estado geral satisfatório.

Trichofolliculomas are well circumscribed, decapsulated dermal nodules composed of one or several large, dilated primary follicles that keratinize on the granular layer, being a rare finding in the feline species. This report addresses the case of a male, castrated, undefined, black coat, 11 years and 5 months old, which was attended at a private veterinary clinic with multiple cutaneous nodules. Six nodules distributed in some areas of the body were identified, where five of these had similar sizes of approximately 1.5 cm, while the anterior limb was about 4 cm in diameter and pedunculated. The patient underwent preoperative exams and was submitted to nodule excision where standard recommendations for safe margin were followed during surgery. The material obtained was 10% formolized and sent to the pathology laboratory at the Clinic School of Veterinary Medicine ofthe Centro Universitário Cesmac in Marechal Deodoro, Alagoas, where it was processed. In the analysis, it was verified that it was a trichofolliculoma because of the morphological description, revealing multiple follicular lobes, with proliferation of epithelial sheath cells and centrally presenting concentric sheets of keratin and coated by a thick and prominent basement membrane. The patient presented an excellent surgical recovery and remained accompanied half-yearly without relapses and with satisfactory general condition.

Los tricofoliculomas son nódulos dérmicos decapsulados bien circunscritos, compuestos de unoo varios folículos primarios grandes y dilatados que se queratinizan en Ia capa granular, siendo un hallazgo raro en las especies felinas. Este informe aborda el caso de un varón felino castrado, indefinido, pelaje negro, de 11anos y 5 meses de edad, que fue atendido en una clínica veterinaria privada con múltiples nódulos cutáneos. Se identificaron seis nódulos distribuidos en algunas áreas del cuerpo, donde cinco de estos tenían tamaños similares de aproximadamente 1.5 cm, mientras que la extremidad anterior tenía unos 4 cm de diámetro y pedunculada. EI paciente se sometió a exámenes preoperatorios y fue sometido a una extirpación de nódulo donde se siguieron las recomendaciones estándar para un margen seguro durante la cirugía. El material obtenidose formolizó ai 1.0% y se envió ai laboratorio de patología de la Escuela Clínica de Medicina Veterinaria del Centro Universitario Cesmac en Marechal Deodoro, Alagoas, donde se procesó. En el análisis, se verificó que se trataba de un tricofoliculoma debido a la descripción morfológica, que revela múltiples lóbulos foliculares, con proliferación de células epiteliales de la vaina y láminas concéntricas de queratina que se presentan centralmente y recubiertas por una membrana basal gruesa y prominente. El paciente presentó una excelente recuperación quirúrgica y permaneció acompariado semestralmente sin recaídas y con un estado general satisfactorio.