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1.
NMR Biomed ; 37(4): e5094, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38214202

RESUMO

We present a review outlining the basic mechanism, background, recent technical developments, and clinical applications of aqueous dielectric padding in the field of MRI. Originally meant to be a temporary solution, it has gained traction as an effective method for correcting B1 + inhomogeneities due to the unique properties of the calcium titanate and barium titanate perovskites used. Aqueous dielectric pads have used a variety of high-permittivity materials over the years to improve the quality of MRI acquisitions at 1.5 and 3 T and more recently for 7 T neuroimaging applications. The technical development and assessment of these pads have been advanced by an increased use of mathematical modeling and electromagnetic simulations. These tools have allowed for a more complete understanding of the physical interactions between dielectric pads and the RF coil, making testing and safety assessments more accurate. The ease of use and effectiveness that dielectric pads offer have allowed them to become more commonplace in tackling imaging challenges in more clinically focused environments. More recently, they have seen usage not only in anatomical imaging methods but also in specialized metabolic imaging sequences such as GluCEST and NOEMTR . New colossally high-permittivity materials have been proposed; however, practical utilization has been a continued challenge due to unfavorable frequency dependences as well as safety limitations. A new class of metasurfaces has been under development to address the shortcomings of conventional dielectric padding while also providing increased performance in enhancing MRI images.


Assuntos
Imageamento por Ressonância Magnética , Neuroimagem , Imageamento por Ressonância Magnética/métodos , Neuroimagem/métodos , Água , Ondas de Rádio , Espectroscopia de Ressonância Magnética , Imagens de Fantasmas
2.
Med Phys ; 50(12): 7606-7618, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37874014

RESUMO

BACKGROUND: The main advantage of ultra-high field (UHF) magnetic resonance neuroimaging is theincreased signal-to-noise ratio (SNR) compared with lower field strength imaging. However, the wavelength effect associated with UHF MRI results in radiofrequency (RF) inhomogeneity, compromising whole brain coverage for many commercial coils. Approaches to resolving this issue of transmit field inhomogeneity include the design of parallel transmit systems (PTx), RF pulse design, and applying passive RF shimming such as high dielectric materials. However, these methods have some drawbacks such as unstable material parameters of dielectric pads, high-cost, and complexity of PTx systems. Metasurfaces are artificial structures with a unique platform that can control the propagation of the electromagnetic (EM) waves, and they are very promising for engineering EM device. Implementation of meta-arrays enhancing MRI has been explored previously in several studies. PURPOSE: The aim of this study was to assess the effect of new meta-array technology on enhancing the brain MRI at 7T. A meta-array based on a hybrid structure consisting of an array of broadside-coupled split-ring resonators and high-permittivity materials was designed to work at the Larmor frequency of a 7 Tesla (7T) MRI scanner. When placed behind the head and neck, this construct improves the SNR in the region of the cerebellum,brainstem and the inferior aspect of the temporal lobes. METHODS: Numerical electromagnetic simulations were performed to optimize the meta-array design parameters and determine the RF circuit configuration. The resultant transmit-efficiency and signal sensitivity improvements were experimentally analyzed in phantoms followed by healthy volunteers using a 7T whole-body MRI scanner equipped with a standard one-channel transmit, 32-channel receive head coil. Efficacy was evaluated through acquisition with and without the meta-array using two basic sequences: gradient-recalled-echo (GRE) and turbo-spin-echo (TSE). RESULTS: Experimental phantom analysis confirmed two-fold improvement in the transmit efficiency and 1.4-fold improvement in the signal sensitivity in the target region. In vivo GRE and TSE images with the meta-array in place showed enhanced visualization in inferior regions of the brain, especially of the cerebellum, brainstem, and cervical spinal cord. CONCLUSION: Addition of the meta-array to commonly used MRI coils can enhance SNR to extend the anatomical coverage of the coil and improve overall MRI coil performance. This enhancement in SNR can be leveraged to obtain a higher resolution image over the same time slot or faster acquisition can be achieved with same resolution. Using this technique could improve the performance of existing commercial coils at 7T for whole brain and other applications.


Assuntos
Imageamento por Ressonância Magnética , Neuroimagem , Humanos , Encéfalo/diagnóstico por imagem , Tronco Encefálico , Cabeça , Imagens de Fantasmas , Ondas de Rádio , Razão Sinal-Ruído , Desenho de Equipamento
3.
J Magn Reson ; 348: 107390, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36774714

RESUMO

In this work, we propose an application of high permittivity materials (HPMs) to improve functional magnetic resonance imaging (fMRI) at 1.5 T, increasing the receive (Rx) sensitivity of a commercial multi-channel head coil. To evaluate the transmit efficiency, specific absorption rate (SAR), and the signal-to-noise ratio (SNR) changes introduced by the HPMs with relative permittivity of 4500, we considered the following configurations in simulation: a whole-body birdcage coil and an Rx-only multi-channel head coil with and without the HPM blocks in the presence of a homogeneous head phantom or a human body model. Experimental studies were also performed with a phantom and with volunteers. Seven healthy volunteers enrolled in a prospective study of fMRI activation in the motor cortex with and without HPMs. fMRI data were analyzed using group-level paired T-tests between acquisitions with and without HPM blocks. Both electromagnetic simulations and experimental measurements showed ∼25% improvement in the Rx sensitivity of a commercial head coil in the areas of interest when HPM blocks were placed in close proximity. It increased the detected motor cortex fMRI activation volume by an average of 56%, thus resulting in more sensitive functional imaging at 1.5 T.


Assuntos
Cerâmica , Imageamento por Ressonância Magnética , Humanos , Imageamento por Ressonância Magnética/métodos , Estudos Prospectivos , Desenho de Equipamento , Simulação por Computador , Razão Sinal-Ruído , Imagens de Fantasmas
4.
Sensors (Basel) ; 22(22)2022 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-36433565

RESUMO

In ultrahigh-field (UHF) magnetic resonance imaging (MRI) system, the RF power required to excite the nuclei of the target object increases. As the strength of the main magnetic field (B0 field) increases, the improvement of the RF transmit field (B1+ field) efficiency and receive field (B1- field) sensitivity of radio-frequency (RF) coils is essential to reduce their specific absorption rate and power deposition in UHF MRI. To address these problems, we previously proposed a method to simultaneously improve the B1+ field efficiency and B1- field sensitivity of 16-leg bandpass birdcage RF coils (BP-BC RF coils) by combining a multichannel wireless RF element (MCWE) and segmented cylindrical high-permittivity material (scHPM) comprising 16 elements in 7.0 T MRI. In this work, we further improved the performance of transmit/receive RF coils. A new combination of RF coil with wireless element and HPM was proposed by comparing the BP-BC RF coil with the MCWE and the scHPM proposed in the previous study and the multichannel RF coils with a birdcage RF coil-type wireless element (BCWE) and the scHPM proposed in this study. The proposed 16-ch RF coils with the BCWE and scHPM provided excellent B1+ field efficiency and B1- field sensitivity improvement.


Assuntos
Imageamento por Ressonância Magnética , Ondas de Rádio , Campos Magnéticos , Núcleo Celular
5.
IEEE Antennas Wirel Propag Lett ; 21(10): 2075-2079, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36388763

RESUMO

Magnetic resonance imaging (MRI) requires spatial uniformity of the radiofrequency (RF) field inside the subject for maximum signal-to-noise ratio (SNR) and image contrast. Bulky high permittivity dielectric pads (HPDPs) focus magnetic fields into the region of interest (ROI) and increase RF field uniformity when placed between the patient and RF coils in the MR scanner. Metamaterials could replace HPDPs and reduce system bulkiness, but those in the literature often require a complicated fabrication process and cannot conform to patient body shape. Proposed is a flexible metamaterial for brain imaging made with a scalable fabrication process using conductive paint and a plastic laminate substrate. The effects of single and double-sided placement of the metamaterial around a human head phantom were investigated in a 3 T scanner. When two metamaterial sheets were wrapped around a head phantom (double-sided placement), the total average signal in the resulting image increased by 10.14% compared to placing a single metamaterial sheet underneath the phantom (single-sided placement). The difference between the maximum and minimum signal intensity values decreased by 57% in six different ROIs with double-sided placement compared to single-sided placement.

6.
Adv Sci (Weinh) ; 9(22): e2202153, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35657031

RESUMO

Elastomers with high dielectric permittivity that self-heal after electric breakdown and mechanical damage are important in the emerging field of artificial muscles. Here, a one-step process toward self-healable, silicone-based elastomers with large and tunable permittivity is reported. Anionic ring-opening polymerization of cyanopropyl-substituted cyclic siloxanes yields elastomers with polar side chains. The equilibrated product is composed of networks, linear chains, and cyclic compounds. The ratio between the components varies with temperature and allows realizing materials with largely different properties. The silanolate end groups remain active, which is the key to self-healing. Elastomeric behavior is observed at room temperature, while viscous flow dominates at higher temperatures (typically 80 °C). The elasticity is essential for reversible actuation and the thermoreversible softening allows for self-healing and recycling. The dielectric permittivity can be increased to a maximum value of 18.1 by varying the polar group content. Single-layer actuators show 3.8% lateral actuation at 5.2 V µm-1 and self-repair after a breakdown, while damaged ones can be recycled integrally. Stack actuators reach an actuation strain of 5.4 ± 0.2% at electric fields as low as 3.2 V µm-1 and are therefore promising for applications as artificial muscles in soft robotics.


Assuntos
Elastômeros , Robótica , Elastômeros/química , Eletricidade , Músculos/fisiologia , Elastômeros de Silicone
7.
MAGMA ; 35(6): 903-909, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35639230

RESUMO

OBJECTIVE: High-permittivity pads have shown promising results in enhancing SNR and transmit efficiency when used for MRI of the brain, but fewer studies have been conducted to examine the performance of high-permittivity pads in other parts of the patient. In this work, we evaluate the impact on SNR and transmit efficiency distributions when high-permittivity pads with different thickness are positioned near the chest of the patient in combination with a transmit/receive array coil. METHODS: The performance of the pads is evaluated through numerical simulations, and both the SNR distribution and the transmit efficiency maps are compared with those obtained when the pads are not present and the distance between the coils and the patient is minimal. The average improvement of SNR and transmit efficiency in the heart is also evaluated for different values of the permittivity of the pads. RESULTS: In the scenario examined, high-permittivity pads can increase SNR and transmit efficiency in the heart volume by as much as 16% and 65%, respectively.


Assuntos
Coração , Imageamento por Ressonância Magnética , Humanos , Imagens de Fantasmas , Desenho de Equipamento , Imageamento por Ressonância Magnética/métodos , Coração/diagnóstico por imagem , Simulação por Computador , Razão Sinal-Ruído
8.
MAGMA ; 35(6): 875-894, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35471464

RESUMO

This article reviews recent developments in designing and testing new types of materials which can be: (i) placed around the body for in vivo imaging, (ii) be integrated into a conventional RF coil, or (iii) form the resonator itself. These materials can improve the quality of MRI scans for both in vivo and magnetic resonance microscopy applications. The methodological section covers the basic operation and design of two different types of materials, namely high permittivity materials constructed from ceramics and artificial dielectrics/metasurfaces formed by coupled conductive subunits, either in air or surrounded by dielectric material. Applications of high permittivity materials and metasurfaces placed next to the body to neuroimaging and extremity imaging at 7 T, body and neuroimaging at 3 T, and extremity imaging at 1.5 T are shown. Results using ceramic resonators for both high field in vivo imaging and magnetic resonance microscopy are also shown. The development of new materials to improve MR image quality remains an active area of research, but has not yet found significant use in clinical applications. This is mainly due to practical issues such as specific absorption rate modelling, accurate and reproducible placement, and acceptable size/weight of such materials. The most successful area has been simple "dielectric pads" for neuroimaging at 7 T which were initially developed somewhat as a stop-gap while parallel transmit technology was being developed, but have continued to be used at many sites. Some of these issues can potentially be overcome using much lighter metasurfaces and artificial dielectrics, which are just beginning to be assessed.


Assuntos
Imageamento por Ressonância Magnética , Neuroimagem , Imagens de Fantasmas , Imageamento por Ressonância Magnética/métodos , Cerâmica , Espectroscopia de Ressonância Magnética
9.
Sensors (Basel) ; 22(5)2022 Feb 23.
Artigo em Inglês | MEDLINE | ID: mdl-35270889

RESUMO

Improvements in transmission and reception sensitivities of radiofrequency (RF) coils used in ultra-high field (UHF) magnetic resonance imaging (MRI) are needed to reduce specific absorption rates (SAR) and RF power deposition, albeit without applying high-power RF. Here, we propose a method to simultaneously improve transmission efficiency and reception sensitivity of a band-pass birdcage RF coil (BP-BC RF coil) by combining a multi-channel wireless RF element (MCWE) with a high permittivity material (HPM) in a 7.0 T MRI. Electromagnetic field (EM-field) simulations, performed using two types of phantoms, viz., a cylindrical phantom filled with oil and a human head model, were used to compare the effects of MCWE and HPM on BP-BC RF coils. EM-fields were calculated using the finite difference time-domain (FDTD) method and analyzed using Matlab software. Next, to improve RF transmission efficiency, we compared two HPM structures, namely, a hollow cylinder shape HPM (hcHPM) and segmented cylinder shape HPM (scHPM). The scHPM and MCWE model comprised 16 elements (16-rad BP-BC RF coil) and this coil configuration demonstrated superior RF transmission efficiency and reception sensitivity along with an acceptable SAR. We expect wider clinical application of this combination in 7.0 T MRIs, which were recently approved by the United States Food and Drug Administration.


Assuntos
Imageamento por Ressonância Magnética , Ondas de Rádio , Campos Eletromagnéticos , Humanos , Imageamento por Ressonância Magnética/métodos , Imagens de Fantasmas , Software , Estados Unidos
10.
Sensors (Basel) ; 22(5)2022 Feb 24.
Artigo em Inglês | MEDLINE | ID: mdl-35270911

RESUMO

This paper reports on a sensor based on multi-element complementary split-ring resonator for the measurement of liquid materials. The resonator consists of three split rings for improved measurement sensitivity. A hole is fabricated at the centre of the rings to accommodate a hollow glass tube, through which the liquid sample can be injected. Electromagnetic simulations demonstrate that both the resonant frequency and quality factor of the sensor vary considerably with the dielectric constant and loss tangent of the liquid sample. The volume ratio between the liquid sample and glass tube is 0.36, yielding great sensitivity in the measured results for high loss liquids. Compared to the design based on rectangular split rings, the proposed ring structure offers 37% larger frequency shifts and 9.1% greater resonant dips. The relationship between dielectric constant, loss tangent, measured quality factor and resonant frequency is derived. Experimental verification is conducted using ethanol solution with different concentrations. The measurement accuracy is calculated to be within 2.8%, and this validates the proposed approach.

11.
Front Robot AI ; 8: 737500, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34616775

RESUMO

Developing highly sensitive flexible pressure sensors has become crucially urgent due to the increased societal demand for wearable electronic devices capable of monitoring various human motions. The sensitivity of such sensors has been shown to be significantly enhanced by increasing the relative dielectric permittivity of the dielectric layers used in device construction via compositing with immiscible ionic conductors. Unfortunately, however, the elastomers employed for this purpose possess inhomogeneous morphologies, and thus suffer from poor long-term durability and unstable electrical response. In this study, we developed a novel, flexible, and highly sensitive pressure sensor using an elastomeric dielectric layer with particularly high permittivity and homogeneity due to the addition of synthesized ionic liquid-grafted silicone oil (denoted LMS-EIL). LMS-EIL possesses both a very high relative dielectric permittivity (9.6 × 105 at 10-1 Hz) and excellent compatibility with silicone elastomers due to the covalently connected structure of conductive ionic liquid (IL) and chloropropyl silicone oil. A silicone elastomer with a relative permittivity of 22 at 10-1 Hz, Young's modulus of 0.78 MPa, and excellent homogeneity was prepared by incorporating 10 phr (parts per hundreds rubber) of LMS-EIL into an elastomer matrix. The sensitivity of the pressure sensor produced using this optimized silicone elastomer was 0.51 kPa-1, which is 100 times higher than that of the pristine elastomer. In addition, a high durability illustrated by 100 loading-unloading cycles and a rapid response and recovery time of approximately 60 ms were achieved. The excellent performance of this novel pressure sensor suggests significant potential for use in human interfaces, soft robotics, and electronic skin applications.

12.
J Magn Reson ; 311: 106681, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31923765

RESUMO

A receive-only surface coil array for 3 Tesla integrating a high-permittivity material (HPM) with a relative permittivity of 660 was designed and constructed and subsequently its performance was evaluated and compared in terms of transmit field efficiency and specific absorption ratio (SAR) during transmission, and signal-to-noise ratio during reception, with a conventional identically-sized surface coil array. Finite-difference time-domain simulations, bench measurements and in-vivo neck imaging on three healthy volunteers were performed using a three-element surface coil array with integrated HPMs placed around the larynx. Simulation results show an increase in local transmit efficiency of the body coil of ~10-15% arising from the presence of the HPM. The receiver efficiency also increased by approximately 15% close to the surface. Phantom experiments confirmed these results. In-vivo scans using identical transmit power resulted in SNR gains throughout the laryngeal area when compared with the conventional surface coil array. In particular specifically around the carotid arteries an average SNR gain of 52% was measured averaged over the three subjects, while in the spine an average of 20% SNR gain was obtained.


Assuntos
Imageamento por Ressonância Magnética/instrumentação , Imageamento por Ressonância Magnética/métodos , Pescoço/diagnóstico por imagem , Algoritmos , Artérias Carótidas/diagnóstico por imagem , Simulação por Computador , Campos Eletromagnéticos , Desenho de Equipamento , Análise de Elementos Finitos , Voluntários Saudáveis , Humanos , Aumento da Imagem , Laringe/diagnóstico por imagem , Imagens de Fantasmas , Razão Sinal-Ruído , Coluna Vertebral/diagnóstico por imagem
13.
Magn Reson Med ; 83(3): 1123-1134, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31502708

RESUMO

PURPOSE: To present a 3T brain imaging study using a conformal prototype helmet constructed with an ultra-high dielectric constant (uHDC; εr ~ 1000) materials that can be inserted into standard receive head-coils. METHODS: A helmet conformal to a standard human head constructed with uHDC materials was characterized through electromagnetic simulations and experimental work. The signal-to-noise ratio (SNR), transmit efficiency, and power deposition with the uHDC helmet inserted within a 20-channel head coil were measured in vivo and compared with a 64-channel head coil and the 20-channel coil without the helmet. Seven healthy volunteers were analyzed. RESULTS: Simulation and in vivo experimental results showed that transmit efficiency was improved by nearly 3 times within localized regions for a quadrature excitation, with a measured global increase of 58.21 ± 6.54% over 7 volunteers. The use of a parallel transmit spokes pulse compensated for severe degradation of B1+ homogeneity, at the expense of higher global and local specific absorption rate levels. A SNR histogram analysis with statistical testing demonstrated that the uHDC helmet enhanced a 20-channel head coil to the level of the 64-channel head coil, with the improvements mainly within the cortical brain regions. CONCLUSION: A prototype uHDC helmet enhanced the SNR of a standard head coil to the level of a high density 64-channel coil, although transmit homogeneity was compromised. Further improvements in SNR may be achievable with optimization of this technology, and could be a low-cost approach for future radiofrequency engineering work in the brain at 3T.


Assuntos
Encéfalo/diagnóstico por imagem , Córtex Cerebral/diagnóstico por imagem , Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética , Posicionamento do Paciente/instrumentação , Imagens de Fantasmas , Algoritmos , Mapeamento Encefálico , Simulação por Computador , Radiação Eletromagnética , Feminino , Voluntários Saudáveis , Humanos , Neuroimagem , Posicionamento do Paciente/métodos , Ondas de Rádio , Reprodutibilidade dos Testes , Razão Sinal-Ruído
14.
Polymers (Basel) ; 13(1)2020 Dec 29.
Artigo em Inglês | MEDLINE | ID: mdl-33383843

RESUMO

In this research, we designed a feasible method to prepare composite films with high permittivity and significantly enhanced hydrophobic performance, which showed huge potential in the electrowetting field. TiO2 nanowire arrays were prepared by a one-step hydrothermal process, and poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) was spin-coated on the nanowire arrays to form composite, the surface of which was modified by electrospinning. Due to the great orientation of TiO2 nanowires, dipoles and space charges are in ordered arrangement along the electric field, and this strongly reinforced the Maxwell-Wagner-Sillars (MWS) polarization, thus the permittivity of the composite (TiO2 nanowire length/film thickness is 0.769) reaches 53 at 1 kHz, which is nearly 3 times higher than pure P(VDF-TrFE). Meanwhile the composite film possesses low dielectric loss (0.07) and low conductivity (2.69 × 10-9 S/cm), showing good insulation. The contact angle of the composite after electrospinning (about 137°) was greatly enhanced from pure P(VDF-TrFE) spin-coated film (about 89°), which can be attributed to the microrough structure built by P(VDF-TrFE) nanofibers.

15.
Macromol Rapid Commun ; 40(16): e1900205, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31206943

RESUMO

The lack of soft high-dielectric-permittivity elastomers responsive to a low voltage has been a long-standing obstacle for the industrialization of dielectric elastomer actuators (DEA) technology. Here, elastomers that not only possess a high dielectric permittivity of 18 and good elastic and insulating properties but are also processable in very thin films by conventional techniques are reported. Additionally, the elastic modulus can be easily tuned. A soft elastomer with a storage modulus of E = 350 kPa, a tanδ = 0.007 at 0.05 Hz, and a lateral actuation strain of 13% at 13 V µm-1 is prepared. A stable lateral actuation over 50 000 cycles at 10 Hz is demonstrated. A stiffer elastomer with an E = 790 kPa, a tanδ = 0.0018 at 0.05 Hz, a large out-of-plane actuation at 41 V µm-1 , and breakdown fields of almost 100 V µm-1 is also developed. Such breakdown fields are the highest ever reported for a high-permittivity elastomer. Additionally, actuators operable at a voltage as low as 200 V are also demonstrated. Because the materials used are cheap and easily available, and the chemical reactions leading to them allow upscaling, they have the potential to advance the DEA technology.


Assuntos
Elastômeros/química , Técnicas Eletroquímicas
16.
Magn Reson Med ; 82(5): 1822-1831, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31199014

RESUMO

PURPOSE: One of the main concerns in fetal MRI is the radiofrequency power that is absorbed both by the mother and the fetus. Passive shimming using high permittivity materials in the form of "dielectric pads" has previously been shown to increase the B1+ efficiency and homogeneity in different applications, while reducing the specific absorption rate (SAR). In this work, we study the effect of optimized dielectric pads for 3 pregnant models. METHODS: Pregnant models in the 3rd, 7th, and 9th months of gestation were used for simulations in a birdcage coil at 3T. Dielectric pads were optimized regions of interest (ROI) using previously developed methods for B1+ efficiency and homogeneity and were designed for 2 ROIs: the entire fetus and the brain of the fetus. The SAR was evaluated in terms of the whole-body SAR, average SAR in the fetus and amniotic fluid, and maximum 10 g-averaged SAR in the mother, fetus, and amniotic fluid. RESULTS: The optimized dielectric pads increased the transmit efficiency up to 55% and increased the B1+ homogeneity in almost every tested configuration. The B1+ -normalized whole-body SAR was reduced by more than 31% for all body models. The B1+ -normalized local SAR was reduced in most scenarios by up to 62%. CONCLUSION: Simulations have shown that optimized high permittivity pads can reduce SAR in pregnant subjects at the 3rd, 7th, and 9th month of gestation, while improving the transmit field homogeneity in the fetus. However, significantly more work is required to demonstrate that fetal imaging is safe under standard operating conditions.


Assuntos
Encéfalo/diagnóstico por imagem , Feto/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Simulação por Computador , Desenho de Equipamento , Feminino , Humanos , Aumento da Imagem/instrumentação , Imageamento por Ressonância Magnética/instrumentação , Modelos Anatômicos , Gravidez
17.
Materials (Basel) ; 12(4)2019 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-30823530

RESUMO

The structure, valence state, and dielectric properties of (Ba1-xSmx)(Ti0.99Mn0.01)O3 (BSTM) (x = 0.02‒0.07) ceramics prepared via a high temperature (1400 °C/12 h) solid state reaction were investigated. A homogeneous and dense microstructure was observed in all samples. With increasing Sm content, the crystal structure changed from tetragonal (x ≤ 0.06) to cubic (x = 0.07) and unit cell volume (V0) decreased continuously, which was mainly due to the substitution of Ba2+ ions by smaller Sm3+ ions in the perovskite lattice. Electron paramagnetic resonance investigation revealed that Mn ions were reduced from high valence to low valence under the role of Sm3+ donor, and only Mn2+ ions were observed at x = 0.07. The Curie temperature (Tc) moved to lower values, from 105.5 down to 20.4 °C, and the x = 0.07 sample satisfied Y5V specification with high permittivity (ε'RT > 13,000) and low loss (tan δ < 0.03).

18.
Magn Reson Med ; 81(5): 3370-3378, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30561797

RESUMO

PURPOSE: High-permittivity materials in the form of flexible "dielectric pads" have proved very useful for addressing RF inhomogeneities in high field MRI systems. Finding the optimal design of such pads is, however, a tedious task, reducing the impact of this technique. We present an easy-to-use software tool which allows researchers and clinicians to design dielectric pads efficiently on standard computer systems, for 7T neuroimaging and 3T body imaging applications. METHODS: The tool incorporates advanced computational methods based on field decomposition and model order reduction as a framework to efficiently evaluate the B1+ fields resulting from dielectric pads. The tool further incorporates optimization routines which can either optimize the position of a given dielectric pad, or perform a full parametric design. The optimization procedure can target either a single target field, or perform a sweep to explore the trade-off between homogeneity and efficiency of the B1+ field in a specific region of interest. The 3T version further allows for shifting of the imaging landmark to enable different imaging targets to be centered in the body coil. RESULTS: Example design results are shown for imaging the inner ear at 7T and for cardiac imaging at 3T. Computation times for all cases are approximately a minute per target field. CONCLUSION: The developed tool can be easily used to design dielectric pads for any 7T neuroimaging and 3T body imaging application within minutes. This bridges the gap between the advanced design methods and the practical application by the MR community.


Assuntos
Orelha Interna/diagnóstico por imagem , Coração/diagnóstico por imagem , Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/instrumentação , Neuroimagem/instrumentação , Imagem Corporal Total , Algoritmos , Gráficos por Computador , Simulação por Computador , Eletricidade , Desenho de Equipamento , Humanos , Software , Interface Usuário-Computador
19.
Magn Reson Med ; 81(4): 2746-2758, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30426554

RESUMO

PURPOSE: To investigate how high-permittivity materials (HPMs) can improve SNR when placed between MR detectors and the imaged body. METHODS: We used a simulation framework based on dyadic Green's functions to calculate the electromagnetic field inside a uniform dielectric sphere at 7 Tesla, with and without a surrounding layer of HPM. SNR-optimizing (ideal) current patterns were expressed as the sum of signal-optimizing (signal-only) current patterns and dark mode current patterns that minimize sample noise while contributing nothing to signal. We investigated how HPM affects the shape and amplitude of these current patterns, sample noise, and array SNR. RESULTS: Ideal and signal-only current patterns were identical for a central voxel. HPMs introduced a phase shift into these patterns, compensating for signal propagation delay in the HPMs. For an intermediate location within the sphere, dark mode current patterns were present and illustrated the mechanisms by which HPMs can reduce sample noise. High-amplitude signal-only current patterns were observed for HPM configurations that shield the electromagnetic field from the sample. For coil arrays, these configurations corresponded to poor SNR in deep regions but resulted in large SNR gains near the surface due to enhanced fields in the vicinity of the HPM. For very high relative permittivity values, HPM thicknesses corresponding to even multiples of λ/4 resulted in coil SNR gains throughout the sample. CONCLUSION: HPMs affect both signal sensitivity and sample noise. Lower amplitude signal-only optimal currents corresponded to higher array SNR performance and could guide the design of coils integrated with HPM.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética , Processamento de Sinais Assistido por Computador , Razão Sinal-Ruído , Algoritmos , Simulação por Computador , Campos Eletromagnéticos , Humanos , Imagens de Fantasmas , Ondas de Rádio , Fatores de Tempo
20.
J Magn Reson ; 299: 59-65, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30580045

RESUMO

OBJECTIVE: The purpose of this work is to investigate the use of ceramic materials (based on BaTiO3 with ZrO2 and CeO2-additives) with very high relative permittivity (εr ∼ 4500) to increase the local transmit field and signal-to-noise ratio (SNR) for commercial extremity coils on a clinical 1.5 T MRI system. METHODS: Electromagnetic simulations of transmit efficiency and specific absorption rate (SAR) were performed using four ferroelectric ceramic blocks placed around a cylindrical phantom, as well as placing these ceramics around the wrist of a human body model. Results were compared with experimental scans using the transmit body coil of the 1.5 T MRI system and an eight-element extremity receive array designed for the wrist. SNR measurements were also performed for both phantom and in vivo scans. RESULTS: Electromagnetic simulations and phantom/in vivo experiments showed an increased in the local transmit efficiency from the body coil of ∼20-30%, resulting in an ∼50% lower transmit power level and a significant reduction in local and global SAR throughout the body. For in vivo wrist experiments, the SNR of a commercial eight-channel receive array, integrated over the entire volume, was improved by ∼45% with the ceramic. CONCLUSION: The local transmit efficiency as well as the SNR can be increased for 1.5 T extremity MRI with commercial array coils by using materials with very high permittivity.

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