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1.
J Clin Nurs ; 2024 Mar 03.
Artigo em Inglês | MEDLINE | ID: mdl-38433374

RESUMO

AIMS AND OBJECTIVES: To investigate evidence-based practices and examine the influence of individual and social system factors on evidence-based practices among nurses in general hospitals. BACKGROUND: Evidence-based practice is essential for improving healthcare quality. However, a challenge for nursing worldwide is nurses' limited use of evidence-based practices. It is crucial to determine the individual and social system factors affecting nurses' use of evidence-based practices. DESIGN: This study employs a multi-institutional cross-sectional design. METHODS: With a multistage random sampling method, 336 registered nurses were recruited from 17 general hospitals in the Republic of the Union of Myanmar. Data were collected through a seven-part questionnaire, including the Evidence-Based Practice Implementation Scale and individual and social system factors. Data were analyzed using descriptive statistics and multiple linear regression. RESULTS: Nurses in general hospitals perceived low levels of evidence-based practices. Individual factors, such as perceived barriers (p < .001), knowledge (p < .001) and attitudes (p = .001), were related to EBP as well as social system factors, including the work environment (p < .001) which influence nurses' practice, explaining 34% variance among nurses. CONCLUSION: Nurses perceived the work environment as the most influencing factor related to evidence-based practices. Individual characteristics, including perceived knowledge, attitudes and barriers, were critical factors in performing evidence-based practices in Myanmar. RELEVANCE TO CLINICAL PRACTICE: Nurse administrators and policymakers can develop strategies and interventions for improving knowledge, attitudes and work environment towards evidence-based practice. Minimizing the barriers to evidence-based practice will promote evidence-based practices in Myanmar general hospitals. IMPACT: In addressing the individual and social system factors influencing the evidence-based practices of nurses, this study contributes to enhancing healthcare quality and outcomes. REPORTING METHOD: This study adhered to the STROBE checklist. PATIENT OR PUBLIC CONTRIBUTION: There was no patient or public contribution.

2.
Environ Mol Mutagen ; 64(7): 401-415, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-37522536

RESUMO

Individual differences in drug response have always existed in clinical treatment. Many non-genetic factors show non-negligible impacts on personalized medicine. Emerging studies have demonstrated epigenetic could connect non-genetic factors and individual treatment differences. We used systematic retrieval methods and reviewed studies that showed individual factors' impact on DNA methylation of drug metabolism genes. In total, 68 studies were included, and half (n = 36) were cohort studies. Six aspects of individual factors were summarized from the perspective of personalized medicine: parental exposure, environmental pollutants exposure, obesity and diet, drugs, gender and others. The most research (n = 11) focused on ABCG1 methylation. The majority of studies showed non-genetic factors could result in a significant DNA methylation alteration in drug metabolism genes, which subsequently affects the pharmacokinetic processes. However, the underlying mechanism remained unknown. Finally, some viewpoints were presented for future research.


Assuntos
Metilação de DNA , Epigênese Genética , Humanos , Metilação de DNA/genética , Dieta
3.
Wiad Lek ; 76(5 pt 1): 1054-1061, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37326089

RESUMO

OBJECTIVE: The aim: Research of a subjectively significant personal social-psychological and individual-psychological characteristic - anxiety in students, which can be a predictor of the occurrence of EBS. To identify the scale and prevalence of the specified predictor in the student environment. PATIENTS AND METHODS: Materials and methods: A survey was conducted among 556 respondents. The survey was conducted according to the Spielberg-Hanin Anxiety Scale, which is available online with automatic scoring and retrieval of results. The test involves determining the levels of situational (reactive) and personal anxiety. To achieve the goal of the research, a set of methods was used: a systematic approach, a sociological method, and a medical-statistical method. The data are provided in the form of relative values with errors. RESULTS: Results: Almost half of the students who participated in the study feel the influence of the anxiety factor, which increases the likelihood of emotional burnout. The "tension" phase - nervous (anxious tension) is a harbinger and "trigger" mechanism in the formation of emotional burnout. According to the results of the study, up to 50% of respondents are in the first phase of emotional burnout or have already passed it. This determines the need for preventive work with students, among whom the survey was conducted, to prevent the occurrence of emotional and, subsequently, professional burnout. The low level of anxiety, which was 8.49% ± 1.18% among respondents, needs further study, as it may indicate the suppression of experiences by consciousness and hidden anxiety, which is an even more provoking factor for emotional burnout than a high level of anxiety. CONCLUSION: Conclusions: Empirical research has established a significant prevalence among students of a high and medium level of personal characteristic - anxiety, which has signs of a negative internal factor and can be a predictor of the development of EBS.


Assuntos
Esgotamento Profissional , Estudantes de Medicina , Humanos , Esgotamento Profissional/epidemiologia , Esgotamento Profissional/psicologia , Esgotamento Psicológico , Ansiedade/epidemiologia , Transtornos de Ansiedade/epidemiologia , Estudantes de Medicina/psicologia , Inquéritos e Questionários
4.
Molecules ; 27(18)2022 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-36144801

RESUMO

The standardization of near-infrared (NIR) spectra is essential in practical applications, because various instruments are generally employed. However, standardization is challenging due to numerous perturbations, such as the instruments, testing environments, and sample compositions. In order to explain the spectral changes caused by the various perturbations, a two-step standardization technique was presented in this work called mutual-individual factor analysis (MIFA). Taking advantage of the sensitivity of a water probe to perturbations, the spectral information from a water spectral region was gradually divided into mutual and individual parts. With aquaphotomics expertise, it can be found that the mutual part described the overall spectral features among instruments, whereas the individual part depicted the difference of component structural changes in the sample caused by operation and the measurement conditions. Furthermore, the spectral difference was adjusted by the coefficients in both parts. The effectiveness of the method was assessed by using two NIR datasets of corn and wheat, respectively. The results showed that the standardized spectra can be successfully predicted by using the partial least squares (PLS) models developed with the spectra from the reference instrument. Consequently, the MIFA offers a viable solution to standardize the spectra obtained from several instruments when measurements are affected by multiple factors.


Assuntos
Espectroscopia de Luz Próxima ao Infravermelho , Água , Calibragem , Análise Fatorial , Análise dos Mínimos Quadrados , Padrões de Referência , Espectroscopia de Luz Próxima ao Infravermelho/métodos
5.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-960452

RESUMO

Background The prevalence rate of work-related musculoskeletal disorders (WMSDs) among manufacturing workers is relatively high and has been widely concerned. However, research on the prevalence and risk factors of multi-site WMSDs is still insufficient. Objective To explore the prevalence and risk factors of multi-site WMSDs of assembly workers in four manufacturing enterprises. Methods The "Chinese Musculoskeletal Questionnaire" was used to conduct a cross-sectional survey among 1401 assembly workers selected by convenient sampling in four manufacturing enterprises, and their demographic characteristics, the prevalence of WMSDs in various body parts, and the information about biomechanical factors, work organizations, work environment, and psychosocial factor exposure were collected. The prevalence of WMSDs and multi-site WMSDs were estimated, Pearson χ2 test was used for univariate analysis of multi-site WMSDs risk factors, and logistic regression was used for multi-factor analysis. Results The total prevalence rate of WMSDs was 54.9% (769/1 401). The top three affected sites were neck (41.4%), shoulders (30.7%), and wrist/hand (25.1%). The prevalence rate of multi-site WMSDs was 41.9% (587/1 401). The prevalence rates of multi-site WMSDs in railway vehicle assembly and riveting workers were higher than those in electronic parts processing and glass manufacturing workers (P<0.001). The results of logistic regression analysis showed that individual factors such as female (OR=2.09, 95%CI: 1.48−2.97) and drinking (OR=1.52, 95%CI: 1.05−2.18), biomechanics factors such as keeping head down for a long time (OR=1.37, 95%CI: 1.22–1.53), keeping bending frequently (OR=1.18, 95%CI: 1.03–1.34), and keeping arms up for a long time (OR=1.25, 95%CI: 1.10–1.41), work organizational factors such as electronic parts processing, railway vehicle assembly, and riveting (OR values were 3.23, 5.70, and 13.83, respectively), environmental factors such as temperature a little cold (OR=4.84, 95%CI: 1.90–12.37), noise seriously affecting work (OR=2.25, 95%CI: 1.23–4.11), and psychosocial factors such as high job demands (OR=1.47, 95%CI: 1.04–2.08), fatigue after work (OR=1.92−2.61) were risk factors of multi-site WMSDs. Conclusion The prevalence rate of multi-site WMSDs in assembly workers is high, and the main influencing factors include individual factors, awkward work postures, environmental factors, and psychosocial factors.

6.
Artigo em Inglês | MEDLINE | ID: mdl-30326573

RESUMO

High accident rates have been a complicated and persistent problem in the Hong Kong construction industry. This situation has stimulated this investigation into factors that influence the risk-taking propensity of construction workers. However, interviewing workers who had a bad experience is problematic because changes in attitude and perception may occur as a result of such an experience. Using quasi-expert interviews can reduce this problem. The objective of this study was to identify factors that influence the risk-taking propensity of construction workers. Semi-structured interviews were conducted with 16 safety professionals all with accident inspection experience and six super-safe workers with no incident record for the past five years. Seven factors that affect the risk-taking propensity of construction workers were successfully identified. Each factor is thoughtfully discussed, and this study shows that quasi-expert interview is a pragmatic approach for deepening the understanding of risk-taking propensity among construction workers. Findings of this study will hopefully help and encourage further quantitative research on the risk-taking propensity of construction workers with different perspectives.


Assuntos
Indústria da Construção , Saúde Ocupacional , Assunção de Riscos , Adolescente , Adulto , Atitude , Feminino , Hong Kong , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários , Adulto Jovem
7.
BMJ Open ; 8(6): e019404, 2018 06 19.
Artigo em Inglês | MEDLINE | ID: mdl-29921679

RESUMO

OBJECTIVE: Stress has major socioeconomic implications for all spheres of employment. It is a trigger for depression, and affects absenteeism, turnover, productivity, morale and suicide. Positive or negative cognitive stress appraisal can be a self-care strategy that affects workers' ability to cope with stress. This study examined cognitive stress appraisal among workers and identified related individual and environmental factors. DESIGN: Cross-sectional study using self-administered postal questionnaires. SETTING: Companies located in two metropolitan areas of Japan (Tokyo and Kanagawa prefectures). PARTICIPANTS: 2311 employees of 48 companies in metropolitan areas in Japan. In total, 341 questionnaires were returned (response rate: 14.8%), 337 of which were suitable for analysis (effective response rate: 98.8%). PRIMARY MEASURES: Cognitive stress appraisal was assessed using the Japanese version of the Perceived Stress Scale (PSS). Potential variables related to stress appraisal included demographic, individual and environmental factors. Multiple regression analysis was used to identify factors related to cognitive stress appraisal. RESULTS: Participants' mean±SD age was 42.8±11.7 years, and two-thirds were male. The mean±SD PSS score was 25.8±6.2. The multiple regression analysis controlled for age, sex and depression showed that those with poorer economic status (ß=0.171, p<0.001), lower electronic health (eHealth) literacy (ß=-0.113, p=0.012), higher traditional organisational climate (ß=0.131, p=0.004) and lower perceived social support (ß=-0.205, p<0.001) experienced significantly higher levels of negatively perceived stress. CONCLUSIONS: The results show individual and environmental factors related to cognitive stress appraisal among workers. An effective strategy to improve mental health among workers may involve an interprofessional approach by public health nurses and health practitioners that includes enhanced self-coping skills using individual workers' eHealth literacy, improvement of organisational climates in workplaces and community-based social support.


Assuntos
Depressão/epidemiologia , Estresse Ocupacional/epidemiologia , Apoio Social , Local de Trabalho/psicologia , Adaptação Psicológica , Adolescente , Adulto , Cognição , Estudos Transversais , Feminino , Humanos , Japão/epidemiologia , Masculino , Saúde Mental , Pessoa de Meia-Idade , Escalas de Graduação Psiquiátrica , Análise de Regressão , Fatores Socioeconômicos , Inquéritos e Questionários , Adulto Jovem
8.
Artigo em Inglês | MEDLINE | ID: mdl-29316685

RESUMO

This study differentiates the risk perception and influencing factors of climate change along the dimensions of global severity and personal threat. Using the 2013 Taiwan Social Change Survey (TSGS) data (N = 2001) as a representative sample of adults from Taiwan, we investigated the influencing factors of the risk perceptions of climate change in these two dimensions (global severity and personal threat). Logistic regression models were used to examine the correlations of individual factors (gender, age, education, climate-related disaster experience and risk awareness, marital status, employment status, household income, and perceived social status) and societal factors (religion, organizational embeddedness, and political affiliations) with the above two dimensions. The results demonstrate that climate-related disaster experience has no significant impact on either the perception of global severity or the perception of personal impact. However, climate-related risk awareness (regarding typhoons, in particular) is positively associated with both dimensions of the perceived risks of climate change. With higher education, individuals are more concerned about global severity than personal threat. Regarding societal factors, the supporters of political parties have higher risk perceptions of climate change than people who have no party affiliation. Religious believers have higher risk perceptions of personal threat than non-religious people. This paper ends with a discussion about the effectiveness of efforts to enhance risk perception of climate change with regard to global severity and personal threat.


Assuntos
Mudança Climática , Política , Opinião Pública , Religião e Psicologia , Meio Social , Adulto , Idoso , Idoso de 80 Anos ou mais , Escolaridade , Feminino , Inquéritos Epidemiológicos , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Taiwan , Adulto Jovem
9.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-626733

RESUMO

Most studies have examined the association of ergonomic risk factors and musculoskeletal discomfort in developed countries. Meanwhile the data are still lacking in developing countries such as Malaysia. The aim of this study was to determine the relation between risk factors and musculoskeletal discomfort among manual material handling workers in Malaysian automotive industries. A total of211 manual material handling workers from automotive industries completed a set of questionnaire on the individual, physical and environmental factors and the prevalence of musculoskeletal discomfort. The Chi-Square test and logistics regression analysis were used to determine the relationship of the risk factors and musculoskeletal. The findings highlighted that job tenure was significantly correlated with musculoskeletal discomfort among the workers (OR=2.33-5.56). The most significant physical risk factor that was associated with musculoskeletal discomfort was bending the trunk forward slightly, hands above knee level, which was significantly related to lower back discomfort (OR=5.13, 95%CI=1.56-16.8), thigh discomfort (OR=5.1, 95%CI=1.01-25.53) and wrist discomfort (OR=3.65, 95%CI=1.06-12.53). Twisting of the trunk (over 45o) and bending sideways were significantly associated to lower back discomfort (OR=4.04, 95%CI=1.44-14.44), and thigh discomfort (OR=4.3, 95%CI=1.29-8.50). The findings also highlighted that environmental factors was associated with musculoskeletal discomfort (p < 0.05. Musculoskeletal discomfort can be reduced by lowering work-related risk factors among automotive manual material handling workers, particularly by focusing on significant factors, including job tenure, bending or twisting postures and environmental factors.

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