RESUMO
OBJECTIVE: To display the low hydraulic resistance channel along the running course of the Conception Vessel (CV) by using in vivo fluorography, so as to provide evidence for the existence of meridians of traditional Chinese medicine from the aspect of interstitial fluid channel. METHODS: A total of 24 male SD rats were randomly divided into 3 groups, namely CV-low impedance spots (CV-LIS), CV-low hydraulic resistance points (CV-LHRP) and non-meridian points (NMP) groups (nï¼8 in each group). The CV-LIS (the imaged line between the xiphoid process and symphysis pubis), CV-LHRP (lateral and parallel to LIS) and NMP (lateral and parallel to CV-LHRP) were detected by using meridian detector and biofluid resistance meter, respectively. Sodium fluorescein solution (1%) was injected into the spot (A-spot, upper 1/5 of the CV-LIS), and one of the NMP (about 1 cm lateral and parallel to the A-spot, and the mid-point between the Kidney and Stomach meridian running courses) by using a microsyringe for observing the migration trace of sodium fluorescein. RESULTS: After injection of fluorescein, the migration trace of fluorescein appeared along the CV-LIS and CV-LHRP lines, and only local diffusion was found in the NMP group. The migration trace lengths along the CV-LIS and CV-LHRP were significantly longer than that of the NMP group (P<0.01), and the migration width of CV-LIS and CV-LHRP groups was significantly smaller than that of the NMP group (P<0.01). The migration speed of CV-LIS and CV-LHRP groups was significantly higher than that of the NMP group (P<0.01). CONCLUSION: Fluorography is able to be used to display the running course of CV, possibly supporting the existence of meridians from the interstitial fluid channel and providing a new method for visualization of meridians.
Assuntos
Meridianos , Animais , Injeções , Masculino , Medicina Tradicional Chinesa , Ratos , Ratos Sprague-Dawley , EstômagoRESUMO
Qi, blood and the meridians are fundamental concepts in Chinese medicine (CM), which are components of the human body and maintain physiological function. Pathological changes of qi, blood and meridians may lead to discomfort and disease. Treatment with acupuncture or herbal medicine aims to regulate qi and blood so as to recover normal function of the meridians. This paper explores the nature of qi as well as compares and correlates them with the structures of the human body. We propose a conceptualization of qi as being similar to the interstitial fluid, and the meridians as being similar to interstitial space of low hydraulic resistance in the body. Hence, qi running in the meridians can be understood as interstitial fluid flowing via interstitial space of low hydraulic resistance.
Assuntos
Líquido Extracelular/fisiologia , Espaço Extracelular/fisiologia , Meridianos , Qi , Água , Pontos de Acupuntura , Tecido Conjuntivo/fisiologia , HumanosRESUMO
Qi, blood and the meridians are fundamental concepts in Chinese medicine (CM), which are components of the human body and maintain physiological function. Pathological changes of qi, blood and meridians may lead to discomfort and disease. Treatment with acupuncture or herbal medicine aims to regulate qi and blood so as to recover normal function of the meridians. This paper explores the nature of qi as well as compares and correlates them with the structures of the human body. We propose a conceptualization of qi as being similar to the interstitial fluid, and the meridians as being similar to interstitial space of low hydraulic resistance in the body. Hence, qi running in the meridians can be understood as interstitial fluid flowing via interstitial space of low hydraulic resistance.
Assuntos
Humanos , Pontos de Acupuntura , Tecido Conjuntivo , Fisiologia , Líquido Extracelular , Fisiologia , Espaço Extracelular , Fisiologia , Meridianos , Qi , ÁguaRESUMO
Objective To measure the interstitial fluid pressure (IFP) on low hydraulic resistance channel along meridians and observe the difference and fluctuation. Method Low hydraulic resistance points (LHRP) and non LHRP were measured on anesthetized mini pigs by a scanning hydraulic resistance measuring device. The IFP was then measured by wick in needle method on these two regions. Results The stomach meridian, kidney meridian and conceptual vessel meridian on mini pigs were measured. The IFP were significantly lower than non LHRP region on the above three meridians(P<0.05), the differences of which were 1.06，0.70，3.69 mmHg respectively with the total pressure difference of 1.44 mmHg and pressure gradient of 1.44~2.88 mmHg/cm（1 mmHg=0．133 kPa）. Conclusions Among the peripheral subcutaneous tissues, there exists a difference of IFP toward the meridian which may drive the flow of interstitial fluid toward the meridians.