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1.
J Maxillofac Oral Surg ; 22(4): 961-965, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38105851

RESUMO

Among the rare congenital malformations, congenital nasal sinuses with blind end are extremely unusual. To the best of our knowledge, a sinus located in the midcolumellar region has not been reported yet. Since there is no consensus about the treatment of midcolumellar sinus, to manage the case as individually as possible was our priority. Considering the patient's age, aesthetic concerns, and requirement of septorhinoplasty in the future, the known inverted V incision was modified to provide surgical excision without any extra scar in the midcolumellar line. This report emphasizes a patient-specific treatment of a 15-year-old female patient presented for congenital sinus in the midcolumellar area. Supplementary Information: The online version contains supplementary material available at 10.1007/s12663-023-02032-0.

2.
Cureus ; 15(10): e46648, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37937012

RESUMO

Foreign body insertion inside the nose is not uncommon in pediatric age groups. It can pass unnoticed by parents, sometimes underdiagnosed or incompletely removed by a clinician. In another scenario, it may be incidentally discovered by imaging during dental workups commonly. This foreign body acts like a nidus for a rhinolith, as it gets calcified over years and becomes like a stone, causing unilateral nasal symptoms. Herein, we present a case of a young female with a rhinolith mistaken for fungal mud. We aim to emphasize this rare clinical condition that, if left unperceived, may lead to complications including, but not limited to, sinusitis, pressure necrosis to the surrounding structure causing septal perforation, or naso-palatal fistula.

3.
Cureus ; 15(7): e41986, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37593272

RESUMO

BACKGROUND:  Paranasal sinus mucoceles are epithelium-lined cystic masses usually resulting from obstruction of sinus ostia. They most frequently occur in the frontal and ethmoid sinuses. The etiology is not clarified, but the most common identifiable cause of mucoceles following functional endoscopic sinus surgery (FESS), trauma, neoplasms, and allergy. The clinical symptoms of mucocele vary and are not specific, the most common being ophthalmic symptoms and headache, impinging on adjacent orbital structures, and causing ophthalmic sequelae such as double vision, commonly followed by orbital swelling, epiphora, proptosis, and ptosis. All patients in this study had frontal and frontoethmoidal mucocele and initially complained of frontal headache and ophthalmic symptoms. Definitive treatment options for paranasal sinus mucoceles include external approaches and endoscopic marsupialization.  Objective: The study aimed to identify the etiology, clinical presentation, most common para nasal sinus affected by mucocele, management, and the rate of recurrence in eight cases with mucocele of the paranasal sinuses. METHODS:  Eight patients diagnosed with mucocele of the paranasal sinuses were admitted to our institution between 2014 and 2021. There were two females and six males aged between 14 and 67. Initial symptoms, duration, clinical presentation upon admission, location of the mucocele, type of surgical intervention, and outcome have all been studied.  Results: The most common symptoms at diagnosis were orbital involvement, retrobulbar, and frontal headache. Most patients were diagnosed with frontal mucocele (40%), and three were frontoethmoidal mucocele at the time of presentation. The rest of the cases were diagnosed with ethmoidal mucocele (25%). The etiology was identified in four patients and was unclear in the rest. All patients underwent endoscopic sinus surgery. The most identifiable postoperative complication was a headache. CONCLUSIONS:  The endonasal endoscopic approach is a safe and effective treatment for paranasal sinus mucocele and provides adequate drainage with a low recurrent rate.

4.
Artigo em Chinês | MEDLINE | ID: mdl-36987953

RESUMO

Objective:To evaluate the efficacy of glucocorticoid sinus stents implanted 2 weeks after functional endoscopic sinus surgery(FESS) for the treatment of chronic rhinosinusitis with nasal polyps(CRSwNP). Methods:CRSwNP patients with similar bilateral lesions were randomly divided into two groups, with a stent group of 25 patients and a control group of 24 patients. Patients in the stent group had glucocorticoid sinus stents implanted into the bilateral ethmoid sinuses 2 weeks after FESS, while the control group underwent postoperative debridement only. Follow-up assessments occurred at postoperative weeks 2, 4, 8, and 12. Patients were asked to assess their sensation of nasal symptoms using a 10-point visual analog scale. Efficacy was assessed by endoscopic evaluations. Sinus obstruction, crusting/coagulation, polyp formation, middle turbinate position, adhesions, mucosa epithelialization, and postoperative intervention were assessed as efficacy outcomes. GraphPad Prism 9 was applied for statistical analysis. Results:At 4 and 8 weeks postoperatively, the stent group showed significant improvement in VAS scores of nasal congestion and runny nose compared with the control group(P<0.05). No significant difference was observed in the VAS scores of head and facial stuffiness, loss of smell, or nasal dryness/crusting between the two groups(P>0.05). Compared with the control group, the stent group had a lower rate of polypoid formation at 4, 8, and 12 weeks postoperatively. At postoperative week 12, the rate of mucosal epithelialization in the ethmoid cavity was significantly higher in the stent group. During the follow-up, the frequency of postoperative intervention was significantly lower in the stent group than in the control group(P<0.05). Besides, a lower incidence of middle turbinate lateralization was found in the stent group at 8 and 12 weeks postoperatively. At 8 weeks postoperatively, the stent group had a percentage of adhesion lower than that of the control group(all P<0.05). Conclusion:Implantation of glucocorticoid sinus stents after FESS can maintain sinus cavity patency, improve the inflammatory status of the operative cavity, reduce postoperative interventions, and promote benign regression of the operative cavity.


Assuntos
Pólipos Nasais , Seios Paranasais , Rinite , Sinusite , Humanos , Pólipos Nasais/cirurgia , Seio Etmoidal/cirurgia , Glucocorticoides/uso terapêutico , Rinite/cirurgia , Sinusite/cirurgia , Seios Paranasais/cirurgia , Endoscopia , Stents , Doença Crônica , Resultado do Tratamento
5.
Clin Case Rep ; 11(1): e6546, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36698519

RESUMO

We report a case of radiation-induced myofibroblastoma of the right nasal cavity in a patient with a remote history of radiotherapy for pediatric retinoblastoma. The patient required maxillectomy and ethmoidectomy. To our knowledge, a rare number of cases have been reported in this location.

6.
Eur Arch Otorhinolaryngol ; 280(2): 743-756, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35900385

RESUMO

BACKGROUND: Nasal sinus cholesteatomas are uncommon slow-growing lesions that are frequently misdiagnosed preoperatively. They can develop due to embryologic remnants or iatrogenic factors (surgical trauma or nasal sinus trauma). In addition, they can cause bone destruction resulting in intracranial or intraorbital complications as well as malignant change if neglected. Complete surgical removal is a must with strict postoperative follow-up. MATERIALS AND METHODS: Three cases of nasal sinus cholesteatoma are reported. The first case was found inside the ethmoidal sinus, the second in the frontal sinus, and the third was found inside a concha bullosa. In all three cases, a wide endoscopic surgical excision was performed. Due to the lateral extension of the lesion, frontal sinus trephine was also used in the case of frontal sinus nasal cholesteatoma. In addition, a review of the English literature for the reported cases of nasal sinus cholesteatomas was conducted. RESULTS: There were no reported recurrence or residual during strict postoperative follow-up for 2 years (by endoscopic examination and diffusion-weighted MRI with delayed postcontrast T1 images). A review of the English literature revealed 42 cases of nasal sinuses cholesteatomas (including the present three cases) (17 in the frontal sinus, 15 in the maxillary sinus, 5 in the ethmoid sinus, 3 in the sphenoid sinus, and 2 in a concha bullosa). CONCLUSIONS: Although nasal sinus cholesteatomas are uncommon, they must be considered in the differential diagnosis of slow-growing nasal sinuses lesions. Preoperative CT scan and diffusion-weighted MRI are essential for proper diagnosis and to exclude other similar lesions, such as nasal sinus mucoceles, cholesterol granuloma, or neoplastic lesions. Wide complete surgical excision is necessary to avoid recurrence and facilitate postoperative follow-up. As with ear cholesteatoma, strict postoperative follow-up is required to detect recurrence or residual early and is performed by endoscopic examination, diffusion-weighted MRI, and delayed post-gadolinium T1 images.


Assuntos
Colesteatoma da Orelha Média , Seio Frontal , Doenças dos Seios Paranasais , Humanos , Doenças dos Seios Paranasais/diagnóstico por imagem , Doenças dos Seios Paranasais/etiologia , Seio Frontal/diagnóstico por imagem , Seio Frontal/cirurgia , Seio Maxilar , Endoscopia/métodos
7.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-982727

RESUMO

Objective:To evaluate the efficacy of glucocorticoid sinus stents implanted 2 weeks after functional endoscopic sinus surgery(FESS) for the treatment of chronic rhinosinusitis with nasal polyps(CRSwNP). Methods:CRSwNP patients with similar bilateral lesions were randomly divided into two groups, with a stent group of 25 patients and a control group of 24 patients. Patients in the stent group had glucocorticoid sinus stents implanted into the bilateral ethmoid sinuses 2 weeks after FESS, while the control group underwent postoperative debridement only. Follow-up assessments occurred at postoperative weeks 2, 4, 8, and 12. Patients were asked to assess their sensation of nasal symptoms using a 10-point visual analog scale. Efficacy was assessed by endoscopic evaluations. Sinus obstruction, crusting/coagulation, polyp formation, middle turbinate position, adhesions, mucosa epithelialization, and postoperative intervention were assessed as efficacy outcomes. GraphPad Prism 9 was applied for statistical analysis. Results:At 4 and 8 weeks postoperatively, the stent group showed significant improvement in VAS scores of nasal congestion and runny nose compared with the control group(P<0.05). No significant difference was observed in the VAS scores of head and facial stuffiness, loss of smell, or nasal dryness/crusting between the two groups(P>0.05). Compared with the control group, the stent group had a lower rate of polypoid formation at 4, 8, and 12 weeks postoperatively. At postoperative week 12, the rate of mucosal epithelialization in the ethmoid cavity was significantly higher in the stent group. During the follow-up, the frequency of postoperative intervention was significantly lower in the stent group than in the control group(P<0.05). Besides, a lower incidence of middle turbinate lateralization was found in the stent group at 8 and 12 weeks postoperatively. At 8 weeks postoperatively, the stent group had a percentage of adhesion lower than that of the control group(all P<0.05). Conclusion:Implantation of glucocorticoid sinus stents after FESS can maintain sinus cavity patency, improve the inflammatory status of the operative cavity, reduce postoperative interventions, and promote benign regression of the operative cavity.


Assuntos
Humanos , Pólipos Nasais/cirurgia , Seio Etmoidal/cirurgia , Glucocorticoides/uso terapêutico , Rinite/cirurgia , Sinusite/cirurgia , Seios Paranasais/cirurgia , Endoscopia , Stents , Doença Crônica , Resultado do Tratamento
8.
BMC Surg ; 22(1): 227, 2022 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-35698063

RESUMO

BACKGROUND: Supernumerary Nostril, also called triple nostrils or accessory nostril, is a rare congenital nasal malformation. CASE PRESENTATION: We report one conceal case of supernumerary nostril in a 19-years-old men which is misdiagnosed to a simple small nasal skin pit. Ordinary surgical excision led to recurrent infection of the lesion postoperatively, and was eventually required secondary surgery and the lesion was finally confirmed by pathological biopsy as a trinasal nostrils. CONCLUSIONS: Through this case, we stress the essential role in differential diagnosis, confirming the diagnosis and seeking for better solutions. Level of Evidence V.


Assuntos
Nariz , Rinoplastia , Adulto , Biópsia , Erros de Diagnóstico , Humanos , Masculino , Nariz/anormalidades , Nariz/cirurgia , Pele , Adulto Jovem
9.
BMC Neurol ; 21(1): 176, 2021 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-33892652

RESUMO

BACKGROUND: Migraine is a primary headache disorder and is the most common disabling primary headache disorder that occurs in children and adolescents. A recent study showed that paranasal air suction can provide relief to migraine headache. However, in order to get the maximum benefit out of it, an easy to use effective air sucker should be available. Aiming to fulfil the above requirement, a randomized, double blind control clinical trial was conducted to investigate the efficacy of a recently developed low-pressure portable air sucker. METHODS: Eighty-six Sri Lankan school children of age 16-19 years with migraine were enrolled for the study. They were randomly allocated into two groups, and one group was subjected to six intermittent ten-second paranasal air suctions using the portable air sucker for 120 s. The other group was subjected to placebo air suction (no paranasal air suction). The effect of suction using portable air sucker was the primary objective but side of headache, type of headache, and gender were also studied as source variables. The primary response studied was severity of headache. In addition, left and right supraorbital tenderness, photophobia, phonophobia, numbness over the face and scalp, nausea and generalized tiredness/weakness of the body were studied. The measurements on all those variables were made before and after suction, and the statistical analysis was performed based on before and after differences. As a follow-up, patients were monitored for 24-h period. RESULTS: There was a significant reduction in the severity of headache pain (OR = 25.98, P < 0.0001), which was the primary outcome variable, and other migraine symptoms studied, tenderness (left) (OR = 289.69, P < 0.0001), tenderness (right) (OR > 267.17, P < 0.0001), photophobia (OR = 2115.6, P < 0.0001), phonophobia (OR > 12.62, P < 0.0001) nausea (OR > 515.59, P < 0.0001) and weakness (OR = 549.06, P < 0.0001) except for numbness (OR = 0.747, P = 0.67) in the treatment group compared to the control group 2 min after the suction. These symptoms did not recur within 24-h period and there were no significant side effects recorded during the 24-h observation period. CONCLUSION: This pilot study showed that low-pressure portable air sucker is effective in paranasal air suction, and suction for 120 s using the sucker can provide an immediate relief which can last for more than 24-h period without any side effects. TRAIL REGISTRATION: Clinical Trial Government Identification Number - 1548/2016. Ethical Clearance Granted Institute - Medical Research Institute, Colombo, Sri Lanka (No 38/2016). Sri Lanka Clinical Trial Registration No: SLCTR/2017/018 . Date of registration = 29/ 06/2017. Approval Granting Organization to use the device in the clinical trial- National Medicines Regulatory Authority Sri Lanka (16 Jan 2018), The device won award at Geneva international inventers exhibition in 2016 and President award in 2018 in Sri Lanka. It is a patented device in Sri Lanka and patent number was SLKP/1/18295. All methods were carried out in accordance with CONSORT 2010 guidelines.


Assuntos
Transtornos de Enxaqueca/terapia , Seios Paranasais , Sucção/instrumentação , Sucção/métodos , Adolescente , Método Duplo-Cego , Feminino , Humanos , Masculino , Projetos Piloto , Sri Lanka , Resultado do Tratamento , Adulto Jovem
10.
Ann Maxillofac Surg ; 10(1): 114-121, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32855926

RESUMO

BACKGROUND: Implant protrusion into the nasal and maxillary sinuses presents a challenge in cases of severely resorbed maxillae. AIM: The aim of this study was to evaluate the clinical and radiographic effects of BECES® implant penetration depth into the nasal and maxillary sinuses. SETTING AND DESIGN: This was an observational study conducted in a tertiary institution. MATERIALS AND METHODS: Forty-nine BECES® implants were inserted into the maxilla of patients who presented with severely resorbed ridges but no history of sinusitis. Forty-five implants protruded into the sinus cavities. Patients were examined clinically and radiographically at 1 week and 3, 6, 12, and 18 months after insertion. Maxillary sinus health, survival and success rates, and peri-implant health were assessed using the plaque index (PI), calculus index, modified gingival index (MGI), and probing pocket depth (PPD). STATISTICAL ANALYSIS: Wilcoxon signed-rank test and Mann-Whitney test were used in this study. RESULTS: Four (8.16%) of the 45 implants that penetrated the cavities reached the sinus floor without disrupting the membrane; the penetration depth was ≥4 mm in 20 implants (44.44%) and <4 mm in 25 (55.56%). No patient showed clinical or radiographic signs of sinusitis during the observation period. There were significant differences in the PI, MGI, and PPD values between baseline and the 18-month follow-up with no association with the penetration depth. All implants showed radiographically direct bone-to-implant contact. Where the implant tip barely reached the sinus floor, the membrane healed uneventfully while when deeply penetrating the sinus, the membrane healed around the implant but did not cover the tip. All prostheses and implants survived during the observation period. CONCLUSION: Penetration depth of polished implants with cortical engagement into the maxillary sinus or the floor of the nose does not negatively affect implant survival, the success rate of the treatment, nor peri-implant soft-tissue health. It also does not provoke the development of sinusitis.

11.
Clin Case Rep ; 7(11): 2194-2201, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31788278

RESUMO

Although extremely rare, sarcomas including malignant peripheral nerve sheath tumors should be considered in the differential diagnosis of sino-nasal tract lesions. Long-term cure is possible through definitive operative management followed by adjuvant therapy.

12.
Auris Nasus Larynx ; 46(2): 252-259, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30082161

RESUMO

OBJECTIVE: Although current therapeutic options for cutaneous melanoma (CM) are constantly improving survival, mucosal melanoma (MM) remains a rare tumor disease with a poor clinical outcome. While radical surgery is the gold standard, clear margin resections in the head and neck area are particularly critical due to high density of vulnerable structures. Adjuvant therapeutic options increases local control and data on the effect of systemic agents is sparse. The aim of this study was to elucidate surgical challenges in the craniofacial area and to evaluate the effect of local and systemic therapy in Head and Neck Mucosal Melanoma (HNMM). METHODS: In total, 21 patients with nasal mucosal malignant melanoma were included in this study over the course of 20 years in two German tertiary referral centers. Patient characteristics and conducted therapy as well as clinical outcomes were analyzed retrospectively. RESULTS: By performing survival analysis for multimodal therapies, we observed a superiority effect of interferon therapy compared to surgery with radiation and surgery alone in the first therapeutic approach. However, patients treated with surgery alone in a recurrent setting showed the best outcome. CONCLUSION: Both, Interferon and radiation as adjuvant therapies, demonstrated survival benefits in initial treatment compared to surgery alone. Analysis after recurrence, however, revealed salvage surgery as a reliable and powerful tool to prolong post-recurrence survival without exposing palliative patients to the risk of severe adverse events from systemic therapies.


Assuntos
Quimioterapia Adjuvante , Neoplasias de Cabeça e Pescoço/terapia , Melanoma/terapia , Mucosa/cirurgia , Recidiva Local de Neoplasia/terapia , Radioterapia Adjuvante , Idoso , Feminino , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Fatores Imunológicos/uso terapêutico , Interferon-alfa/uso terapêutico , Masculino , Margens de Excisão , Melanoma/patologia , Pessoa de Meia-Idade , Mucosa Bucal/patologia , Mucosa Bucal/cirurgia , Neoplasias Bucais/patologia , Neoplasias Bucais/terapia , Mucosa/patologia , Mucosa Nasal/patologia , Mucosa Nasal/cirurgia , Estadiamento de Neoplasias , Neoplasias Nasais/patologia , Neoplasias Nasais/terapia , Neoplasias dos Seios Paranasais/patologia , Neoplasias dos Seios Paranasais/terapia , Neoplasias Faríngeas/patologia , Neoplasias Faríngeas/terapia , Radioterapia de Intensidade Modulada , Estudos Retrospectivos
13.
Eur Arch Otorhinolaryngol ; 275(8): 2079-2088, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29869159

RESUMO

OBJECTIVES: Orbital infections are regularly encountered and are managed by various healthcare disciplines. Sepsis of the orbit and adjacent tissues can be associated with considerable acute complication and long-term sequelae. Therefore, prompt recognition and management of this condition are crucial. This article presents the outcomes of a 7-year complete cycle audit project and describes the development of the new local guideline on the management of orbital infections in our tertiary centre. METHODS: (1) A retrospective 5-year audit cycle on patients with orbital infections. (2) A review of available evidence on the management of orbital infections. (3) A new local multidisciplinary guideline on the management of orbital infections. (4) A retrospective 2-year second audit cycle to assess the clinical outcomes. RESULTS: Various disciplines intersect in the management of orbital infections. Standardising the management of this condition proved to be achievable through the developed guideline. However, room for improvement in practice exists in areas such as the promptness in referring patients to specialist care, the multidisciplinary assessment of patients on admission, and the improvement of scanning requests of patients.


Assuntos
Auditoria Clínica , Gerenciamento Clínico , Infecções Oculares/terapia , Órbita/diagnóstico por imagem , Doenças Orbitárias/terapia , Guias de Prática Clínica como Assunto , Adolescente , Adulto , Criança , Pré-Escolar , Progressão da Doença , Infecções Oculares/diagnóstico , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Orbitárias/diagnóstico , Estudos Retrospectivos , Fatores de Tempo , Adulto Jovem
14.
J Zoo Wildl Med ; 49(2): 444-449, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29900774

RESUMO

African rhinoceros are poached for their horns using indiscriminate and aggressive methods. Rhinoceros that survive these attacks often have severe facial trauma, and treatment is limited by a lack of understanding and published information of the normal anatomy. This study was performed to investigate and describe the anatomy of the most commonly injured area of the head of the white rhinoceros ( Ceratotherium simum). Two white rhinoceros cadaver heads were imaged by computed tomography and grossly dissected. A combined dorsal conchal sinus and nasal sinus (named the nasoconchal sinus) was identified and confirmed to be readily exposed by horn removal. The nasoconchal sinus communicates via a relatively large opening with the middle nasal meatus of the nasal cavity. Awareness of the combined sinus space and its single communicating pathway will assist with accurate assessment and treatment of trauma to the dorsal facial region of the white rhinoceros.


Assuntos
Traumatismos Craniocerebrais/veterinária , Cabeça/diagnóstico por imagem , Seios Paranasais/diagnóstico por imagem , Perissodáctilos/anatomia & histologia , Medicina Veterinária/métodos , Animais , Cadáver , Traumatismos Craniocerebrais/diagnóstico por imagem , Feminino , Cornos/lesões , Tomografia Computadorizada por Raios X/veterinária
15.
Journal of Medical Postgraduates ; (12): 481-484, 2018.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-700857

RESUMO

Objective Early diagnosis of extra-nodal nasal type NK /T cell lymphoma (ENKTCL) is difficult and it is often misdiagnosed.This article was to analyze the CT and MRI findings of ENKTCL originating in the nasal cavity or sinus and investigate the values of CT and MRI in the diagnosis of the disease . Methods We retrospectively analyzed the clinical data and CT and MRI findings about 13 cases of ENKTCL originating in the nasal cavity or sinus examined in our hospital from January 2012 to December 2017. Results Non-contrast CT scanning displayed soft tissue density shadow in the nasal cavity or sinus , with homogeneous density in the tumor and soft tissue mass with bony destruction ( mostly infiltrative absorption) in the midline nasal cavity and sinal area , and the area of soft tissue lesion was obviously larger than that of bony de -struction.Ten cases of contrast-enhanced CT of the tumor manifested mild to moderate heterogeneous density ; 10 cases of plain MRI pres-ented isointensity of T1WI and slightly increased intensity of T 2WI, while enhanced MRI showed mild to moderate heterogeneous density . Low-intensity T1WI, high-intensity T2WI and edge-enhancement were observed in the 10 cases accompanied by obstructive sinusitis . Conclusion ENKTCL originating in the nasal cavity or sinus has its own specific CT or /and MRI manifestations.Conventional CT or /and MRI combined with clinical signs and symptoms can accurately determine the site of lesion and scope of invasion and is therefore of important clinical significance for the early diagnosis and prognosis of the disease.

16.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ; 31(17): 1355-1358, 2017 Sep 05.
Artigo em Chinês | MEDLINE | ID: mdl-29798231

RESUMO

Objective:To analyze the anatomical and developmental characteristics of nasal sinuses in 2-3 years old children.Method:Coronal CT scans of 62 cases (2-3 years old children) were studied with the imaging station. The gasification conditions of the sinuses were identified and measured.Result:The mean of the transverse and vertical diameters for the left side of the maxillary sinuse was (17.51±2.92)mm and (16.63±3.46)mm. Those for the right side were (17.28±2.51)mm and (17.24±3.72)mm. The mean for the left side of the anterior ethmoid sinus were (5.06±1.18)mm and (13.61±2.49)mm. Those for its right side were (5.00±1.45)mm and (13.64±2.30)mm. The mean for the left side of the posterior ethmoid sinus were (7.94±1.72)mm and (12.80±1.78)mm. Those for the right side were (7.88±1.85)mm and (12.64±.96)mm.96.77%(120 sides) of the sphenoid sinuses were developed. The mean for the left side of the sphenoid sinus were (7.38±3.11)mm and (8.67±3.14)mm. Those for the right side were (7.48±2.70)mm and (8.63±2.42)mm. 30.65% (38 sides) of the frontal sinuses were developed.Conclusion:The all nasal sinuses in 2-3 years old children have been already developed. The pneumatization of the frontal sinus was defined in some babies. It can help radiologist make correct diagnosis of paranasal sinuses in children.


Assuntos
Seio Etmoidal/anatomia & histologia , Seio Frontal/anatomia & histologia , Seios Paranasais/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Pré-Escolar , Feminino , Humanos , Masculino , Seio Esfenoidal
17.
Hum Pathol ; 63: 139-143, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-27916624

RESUMO

Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumor of the salivary glands made up of clear cells that form cords and nests in hyalinized stroma. To date, primary HCCCs of the paranasal sinus have not been described. This article presents 2 cases of HCCC of the maxillary sinus with unusual glandular formation and lymphoplasmacytic stroma in case 1 and a characteristic solid nest pattern and fibrocellular and hyalinized stroma in case 2. Immunohistochemical studies excluded myoepithelial origin and sinonasal renal cell-like adenocarcinomas. Negativity for p63 and p40 in case 1 ruled out a squamous cell origin. Both cases showed a rearranged EWSR1 gene. Reverse-transcription polymerase chain reaction detected EWSR1-ATF1 fusion gene transcripts, and Sanger sequencing confirmed an EWSR1 exon 11 fused in-frame to ATF exon 3.


Assuntos
Biomarcadores Tumorais/genética , Carcinoma/genética , Fusão Gênica , Neoplasias do Seio Maxilar/genética , Proteínas de Fusão Oncogênica/genética , Idoso de 80 Anos ou mais , Biomarcadores Tumorais/análise , Biópsia , Carcinoma/química , Carcinoma/patologia , Carcinoma/terapia , Endoscopia , Éxons , Predisposição Genética para Doença , Humanos , Imuno-Histoquímica , Hibridização in Situ Fluorescente , Masculino , Neoplasias do Seio Maxilar/química , Neoplasias do Seio Maxilar/patologia , Neoplasias do Seio Maxilar/terapia , Pessoa de Meia-Idade , Fenótipo , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Análise de Sequência de DNA , Células Estromais/química , Células Estromais/patologia , Tomografia Computadorizada por Raios X
18.
J Pediatr Neurosci ; 11(2): 156-8, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27606030

RESUMO

Twin nasal dermal sinus with associated intracranial dermoid located in interfalcial region is a very rare occurrence and is reported only in the occipital and temporal regions. However, multiple sinuses located in the canthus and dorsum of nose are not reported till date. Authors report an interesting first case of interfalcial dermoid cyst associated with twin discharging dermal sinuses, who underwent successful surgical repair in the world literature. The authors report the management of an unusual case and the review has been discussed briefly.

19.
Ciênc. rural ; 46(7): 1262-1267, July 2016. tab, graf
Artigo em Inglês | LILACS | ID: lil-780862

RESUMO

ABSTRACT: Cattle have extensive paranasal sinuses that are susceptible to disease, most commonly sinusitis. The sinuscopy can be used to evaluate these structures, although there are no descriptions of this region for endoscopic anatomy, especially regarding the trocar position and the most appropriate type of endoscope. This study aimed to standardize the surgical approaches to sinuscopy in cattle by comparing the use of three endoscopes. Four accesses by trephination (one hole for each of the maxillary and frontal sinuses) were made in eight heads of slaughtered cattle. Each hole was inspected with three endoscopes: a 10mm flexible colonoscope with up to 180º of angulation, a 10mm 0° laparoscope and a 4mm 30º arthroscope. It was observed that all regions of the maxillary sinus were better visualized with the 4mm endoscope, and the structures of this sinus were less well visualized with the 10mm laparoscope. The frontal sinus was difficult to evaluate due to the tortuosity of its bony projections, and the cranial portion was not observed by the proposed accesses. The caudal regions of the frontal sinus such as the nuchal diverticulum and the back of the orbit had the greatest number of structures visualized by the 4mm endoscope, followed by the colonoscope. The comparative analysis showed that the 4mm endoscope was most efficient and could be adapted to sinuscopy in cattle.


RESUMO: Os bovinos apresentam seios paranasais extensos e passíveis de afecções, como a sinusite. A sinuscopia, técnica já utilizada em outras espécies, avalia os seios paranasais de modo pouco invasivo e não é descrita em bovinos. O presente estudo objetivou padronizar os acessos cirúrgicos para sinuscopia em bovinos, testando três técnicas de videoendoscopia. Foram selecionadas oito cabeças de bovinos provenientes de abatedouro comercial, sendo realizada a trepanação dos seios maxilares e frontais de ambos os lados (um orifício por seio). Cada seio foi inspecionado com três óticas: um colonoscópio flexível com 10mm de diâmetro e até 180º de angulação, um laparoscópio rígido de 10mm e 0º e um artroscópio rígido de 4mm e 30º. Na região caudal do seio maxilar, os alvéolos e abertura maxilopalatina foram visualizadas com todas as óticas. A região caudodorsomedial e rostral do seio maxilar foram observadas com a ótica flexível e a rígida de 4mm, sendo que apenas esta adentrou no seio palatino. O seio frontal é de difícil visualização, devido à tortuosidade de suas projeções ósseas e sua porção cranial não foi observada pelo acesso proposto. A região caudal do seio frontal, o divertículo nucal e a área caudal à órbita tiveram o maior número de estruturas visualizadas com a ótica rígida de 4mm, seguida da flexível. A análise comparativa demonstra que a técnica utilizando a ótica rígida de 4mm permite a visualização de um maior número de estruturas com maior detalhamento e é a que mais se adapta à sinuscopia em bovinos.

20.
Vet Pathol ; 53(3): 621-4, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26253881

RESUMO

Chondro-osseous respiratory epithelial adenomatoid hamartomas (COREAHs) are rare tumors in the nasal cavity of people, which have not been described in other species. COREAHs in people are minimally invasive and rarely recur following excision. Histologically, these tumors are composed of disorganized, mature, nasal turbinate tissue that is organized into polypoid growths. These growths are lined by respiratory epithelium, contain glandular elements, and are organized around central cores of chondro-osseous matrix. This report describes 3 cases of dogs with nasal tumors that have histomorphology similar to that of COREAH in people. The tumors were all identified within the nasal cavity and were associated with regional bony lysis of the turbinates and surrounding skull bones, a feature that has not been reported in COREAH in people. There was no evidence of metastasis or extension beyond the nasal cavity in any of the 3 cases.


Assuntos
Doenças do Cão/patologia , Hamartoma/veterinária , Doenças Nasais/veterinária , Adenoma/diagnóstico , Adenoma/patologia , Adenoma/veterinária , Animais , Osso e Ossos/patologia , Doenças do Cão/diagnóstico , Cães , Feminino , Hamartoma/diagnóstico , Hamartoma/patologia , Masculino , Cavidade Nasal/patologia , Doenças Nasais/diagnóstico , Doenças Nasais/patologia , Mucosa Respiratória/patologia , Tomografia Computadorizada por Raios X/veterinária
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