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1.
Longit Life Course Stud ; 15(3): 394-406, 2024 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-38954409

RESUMO

This study aims to evaluate the temporal trend in the quality of cause-of-death data and garbage code profiles and to determine its association with socio-economic status in Serbia. A longitudinal study was assessed using data from mortality registers from 2005 to 2019. Computer application Analysis of Causes of National Deaths for Action (ANACONDA) calculates the distribution of garbage codes by severity and composite quality indicator: Vital Statistics Performance Index for Quality (VSPI(Q)). A relationship between VSPI(Q) and country development was estimated by analysing two socio-economic indicators: the Socio-demographic Index and the Human Development Index (HDI). Serbia indicates progress in strengthening cause-of-death statistics. The steady upward trend of the VSPI(Q) index has risen from 55.6 (medium quality) to 70.2 (high quality) over the examined years. Significant reduction of 'Insufficiently specified causes with limited impact' (Level 4) and an increase in the trend of 'High-impact garbage codes' (Levels 1 to 3) were evident. Decreased deaths of no policy value (annual percentage change of -1.41%) have manifested since 2014. A strong positive association between VSPI(Q) and socio-economic indicators was assessed, where the HDI has shown a stronger association with VSPI(Q). Improved socio-economic conditions on the national level are followed by enhanced cause-of-death data quality. Upcoming actions to improve quality should be directed at high-impact garbage codes. The study underlines the need to prioritise the education and training of physicians with a crucial role in death certification to overcome many cause-of-death quality issues identified in this assessment.


Assuntos
Causas de Morte , Humanos , Sérvia/epidemiologia , Causas de Morte/tendências , Estudos Longitudinais , Fatores Socioeconômicos , Sistema de Registros , Confiabilidade dos Dados , Estatísticas Vitais
2.
BMC Plant Biol ; 24(1): 690, 2024 Jul 19.
Artigo em Inglês | MEDLINE | ID: mdl-39030485

RESUMO

BACKGROUND: Sorghum (Sorghum bicolor) is a promising opportunity crop for arid regions of Africa due to its high tolerance to drought and heat stresses. Screening for genetic variability in photosynthetic regulation under salt stress can help to identify target trait combinations essential for sorghum genetic improvement. The primary objective of this study was to identify reliable indicators of photosynthetic performance under salt stress for forage yield within a panel of 18 sorghum varieties from stage 1 (leaf 3) to stage 7 (late flowering to early silage maturity). We dissected the genetic diversity and variability in five stress-sensitive photosynthetic parameters: nonphotochemical chlorophyll fluorescence quenching (NPQ), the electron transport rate (ETR), the maximum potential quantum efficiency of photosystem II (FV/FM), the CO2 assimilation rate (A), and the photosynthetic performance based on absorption (PIABS). Further, we investigated potential genes for target phenotypes using a combined approach of bioinformatics, transcriptional analysis, and homologous overexpression. RESULTS: The panel revealed polymorphism, two admixed subpopulations, and significant molecular variability between and within population. During the investigated development stages, the PIABS varied dramatically and consistently amongst varieties. Under higher saline conditions, PIABS also showed a significant positive connection with A and dry matter gain. Because PIABS is a measure of plants' overall photosynthetic performance, it was applied to predict the salinity performance index (SPI). The SPI correlated positively with dry matter gain, demonstrating that PIABS could be used as a reliable salt stress performance marker for forage sorghum. Eight rubisco large subunit genes were identified in-silico and validated using qPCR with variable expression across the varieties under saline conditions. Overexpression of Rubisco Large Subunit 8 increased PIABS, altered the OJIP, and growth with an insignificant effect on A. CONCLUSIONS: These findings provide insights into strategies for enhancing the photosynthetic performance of sorghum under saline conditions for improved photosynthetic performance and potential dry matter yield. The integration of molecular approaches, guided by the identified genetic variability, holds promise for genetically breeding sorghum tailored to thrive in arid and saline environments, contributing to sustainable agricultural practices.


Assuntos
Variação Genética , Fotossíntese , Estresse Salino , Sorghum , Sorghum/genética , Sorghum/fisiologia , Sorghum/metabolismo , Estresse Salino/genética , Clorofila/metabolismo
3.
J Environ Manage ; 366: 121741, 2024 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-38986379

RESUMO

Ecological risk management has emerged as a critical research and policy development area in energy and environmental economics. Sustained ecology is crucial for the standard of living and food security. As the adverse impacts of environmental degradation and climate change become increasingly apparent it is imperative to understand ecological risk and its interconnectedness with environmental pressure, clean energy, economic activity, globalization, and green technology. Ecological risk is assessed using the environmental performance index which is a holistic indicator of climate change, environmental pressures and human actions in which most of these indicators have spatial effects. This paper explores the multifaceted relationship between identified anthropogenic critical factors and their role in effectively managing ecological risk globally. This study has developed the second-generation dynamic panel quantile regression considering spatial effects of economic activities on ecology across borders of 55 countries between 1995 and 2022. This innovative hybrid estimation scheme that integrated theoretical and econometric aspects makes the model robust to major regression issues. Several implications ranked in decreasing order of its effectiveness are reducing environmental pressure, expediting energy transition, and embracing economic integration while there is a need to work on rejuvenating green technology and green growth.

4.
BMC Musculoskelet Disord ; 25(1): 522, 2024 Jul 05.
Artigo em Inglês | MEDLINE | ID: mdl-38970051

RESUMO

BACKGROUND: For the treatment of coronoid process fractures, medial, lateral, anterior, anteromedial, and posterior approaches have been increasingly reported; however, there is no general consensus on the method of fixation of coronal fractures. Here, we present a highly-extensile minimally invasive approach to treat coronoid process fractures using a mini-plate that can achieve anatomic reduction, stable fixation, and anterior capsular repair. Further, the study aimed to determine the complication rate of the anterior minimally invasive approach and to evaluate functional and clinical patient-reported outcomes during follow-up. METHODS: Thirty-one patients diagnosed with coronoid fractures accompanied with a "terrible triad" or posteromedial rotational instability between April 2012 and October 2018 were included in the analysis. Anatomical reduction and mini-plate fixation of coronoid fractures were performed using an anterior minimally invasive approach. Patient-reported outcomes were evaluated using the Mayo Elbow Performance Index (MEPI) score, range of motion (ROM), and the visual analog score (VAS). The time of fracture healing and complications were recorded. RESULTS: The mean follow-up time was 26.7 months (range, 14-60 months). The average time to radiological union was 3.6 ± 1.3 months. During the follow-up period, the average elbow extension was 6.8 ± 2.9° while the average flexion was 129.6 ± 4.6°. According to Morrey's criteria, 26 (81%) elbows achieved a normal desired ROM. At the last follow-up, the mean MEPI score was 98 ± 3.3 points. There were no instances of elbow instability, elbow joint stiffness, subluxation or dislocation, infection, blood vessel complications, or nerve palsy. Overall, 10 elbows (31%) experienced heterotopic ossification. CONCLUSION: An anterior minimally invasive approach allows satisfactory fixation of coronoid fractures while reducing incision complications due to over-dissection of soft tissue injuries. In addition, this incision does not compromise the soft tissue stability of the elbow joint and allows the patient a more rapid return to rehabilitation exercises.


Assuntos
Placas Ósseas , Articulação do Cotovelo , Fixação Interna de Fraturas , Fraturas Cominutivas , Amplitude de Movimento Articular , Fraturas da Ulna , Humanos , Masculino , Feminino , Fraturas da Ulna/cirurgia , Fraturas da Ulna/diagnóstico por imagem , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Pessoa de Meia-Idade , Adulto , Fraturas Cominutivas/cirurgia , Fraturas Cominutivas/diagnóstico por imagem , Articulação do Cotovelo/cirurgia , Articulação do Cotovelo/diagnóstico por imagem , Articulação do Cotovelo/fisiopatologia , Resultado do Tratamento , Estudos Retrospectivos , Seguimentos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Consolidação da Fratura , Idoso , Medidas de Resultados Relatados pelo Paciente , Adulto Jovem
5.
Environ Sci Pollut Res Int ; 31(32): 45035-45054, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38955976

RESUMO

Air pollution is a pressing environmental concern in urban areas, especially in densely populated cities like Delhi, India. However, plant species can effectively capture airborne suspended pollutants. Given this, the present study aimed to investigate the seasonal variations (pre- and post-monsoon) in the pollution-mitigating potential, biochemical characteristics, and suspended particulate matter (SPM) capturing capacities of select plant species in Delhi. Also, using biochemical parameters, plant morphology, and socioeconomic factors, the study computed tolerance indices such as the Air Pollution Tolerance Index (APTI) and Anticipated Performance Index (API). Ficus religiosa L. exhibited the highest APTI value of 11.94, while Polyalthia longifolia (Sonn.) Thwaites displayed the lowest 7.99 APTI value during the pre-monsoon. Ficus benghalensis L. showed the maximum SPM adhesion on the leaves, with a deposition of 1305.46 µg/cm2, whereas F. religiosa exhibited the lowest SPM deposition of 56.62 µg/cm2. Moreover, the statistical analysis indicated a positive correlation between ascorbic acid and chlorophyll content (R2 > 0.6) with APTI. Also, F. religiosa demonstrated a significant Pearson's correlation (P < 0.05) between chlorophyll content and SPM deposition during the pre-monsoon. The study highlighted the dynamic nature of plant-based air pollution mitigation. It offered valuable insights into the potential of green infrastructure as a sustainable solution for addressing air quality concerns in urban environments. The results emphasized the significance of selecting adequate plant species and considering seasonal variations in developing urban greening strategies to combat air pollution.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Monitoramento Ambiental , Material Particulado , Plantas , Estações do Ano , Material Particulado/análise , Poluentes Atmosféricos/análise , Índia , Cidades
6.
J Environ Health Sci Eng ; 22(1): 123-137, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38887769

RESUMO

Purpose: This study aimed to present an index (IEP) to evaluate the environmental performance of the sugar-energy industrial process based on the waste generated in manufacturing operations. The residues considered in this study were: vinasse, filter cake, ash and soot, residual waters, and sewage sludge. Methods: The index created was developed to take into account, and to be directly proportional to the environmental impact of each residue generated by the sugar-energy production, to the relative spatial dispersion that each waste can reach, and to the environmental fragility of the hydrographic basin where the plant under evaluation is inserted and works. The lower IEP, the better the company valuation. Results: The index was tested in a real company and exhibited an IEP Total = 1,4.1013 km2.p/yr, which shows weak waste management by the enterprise. Vinasse was responsible for 50% of the IEP Total, while filter cake contributed 45% to it. Ash and soot, residual waters, and sewage sludge were together responsible for 5% of the IEP Total. Conclusion: The theoretical conception used in this study is inspiring for the development of new studies on environmental assessment measurement. The study showed that vinasse is the most problematic waste in environmental terms, a conclusion that is in line with academic studies. Nevertheless, the waste with the greatest potential impact on the environment is filter cake. Despite this, filter cake presented a lower IEP(i) than vinasse, given that its negative impact on the basin is smaller. Both wastes contributed 95% of the IEP Total, which places them among the residues to be managed with greater attention.

7.
Polymers (Basel) ; 16(9)2024 Apr 25.
Artigo em Inglês | MEDLINE | ID: mdl-38732666

RESUMO

Simulation models are used to design extruders in the polymer processing industry. This eliminates the need for prototypes and reduces development time for extruders and, in particular, extrusion screws. These programs simulate, among other process parameters, the temperature and pressure curves in the extruder. At present, it is not possible to predict the resulting melt quality from these results. This paper presents a simulation model for predicting the melt quality in the extrusion process. Previous work has shown correlations between material and thermal homogeneity and the screw performance index. As a result, the screw performance index can be used as a target value for the model to be developed. The results of the simulations were used as input variables, and with the help of artificial intelligence-more precisely, machine learning-a linear regression model was built. Finally, the correlation between the process parameters and the melt quality was determined, and the quality of the model was evaluated.

8.
Arch Gynecol Obstet ; 310(2): 719-728, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38789851

RESUMO

PURPOSE: To elucidate the association between arterial and venous Doppler ultrasound parameters and the risk of secondary cesarean delivery for intrapartum fetal compromise (IFC) and neonatal acidosis in small-for-gestational-age (SGA) fetuses. METHODS: This single-center, prospective, blinded, cohort study included singleton pregnancies with an estimated fetal weight (EFW) < 10th centile above 36 gestational weeks. Upon study inclusion, all women underwent Doppler ultrasound, including umbilical artery (UA) pulsatility index (PI), middle cerebral artery (MCA) PI, fetal aortic isthmus (AoI) PI, umbilical vein blood flow (UVBF), and modified myocardial performance index (mod-MPI). Primary outcome was defined as secondary cesarean section due to IFC. RESULTS: In total, 87 SGA pregnancies were included, 16% of which required a cesarean section for IFC. Those fetuses revealed lower UVBF corrected for abdominal circumference (AC) (5.2 (4.5-6.3) vs 7.2 (5.5-8.3), p = 0.001). There was no difference when comparing AoI PI, UA PI, ACM PI, or mod-MPI. No association was found for neonatal acidosis. After multivariate logistic regression, UVBF/AC remained independently associated with cesarean section due to IFC (aOR 0.61 [0.37; 0.91], p = 0.03) and yielded an area under the curve (AUC) of 0.78 (95% CI, 0.67-0.89). A cut-off value set at the 50th centile of UVBF/AC reached a sensitivity of 86% and specificity of 58% for the occurrence of cesarean section due to IFC (OR 8.1; 95% CI, 1.7-37.8, p = 0.003). CONCLUSION: Low levels of umbilical vein blood flow (UVBF/AC) were associated with an increased risk among SGA fetuses to be delivered by cesarean section for IFC.


Assuntos
Cesárea , Recém-Nascido Pequeno para a Idade Gestacional , Artéria Cerebral Média , Ultrassonografia Doppler , Ultrassonografia Pré-Natal , Artérias Umbilicais , Humanos , Feminino , Gravidez , Estudos Prospectivos , Adulto , Artérias Umbilicais/diagnóstico por imagem , Artéria Cerebral Média/diagnóstico por imagem , Artéria Cerebral Média/embriologia , Recém-Nascido , Acidose , Veias Umbilicais/diagnóstico por imagem , Fluxo Pulsátil , Sofrimento Fetal/diagnóstico por imagem , Retardo do Crescimento Fetal/diagnóstico por imagem , Peso Fetal
9.
Water Sci Technol ; 89(7): 1647-1664, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38619895

RESUMO

The study evaluated the impact of treated wastewater on plant growth through the use of hyperspectral and fluorescence-based techniques coupled with classical biomass analyses, and assessed the potential of reusing treated wastewater for irrigation without fertilizer application. Cherry tomato (Solanum lycopersicum) and cabbage (Brassica oleracea L.) were irrigated with tap water (Tap), secondary effluent (SE), and membrane effluent (ME). Maximum quantum yield of photosystem II (Fv/Fm) of tomato and cabbage was between 0.78 to 0.80 and 0.81 to 0.82, respectively, for all treatments. The performance index (PI) of Tap/SE/ME was 2.73, 2.85, and 2.48 for tomatoes and 4.25, 3.79, and 3.70 for cabbage, respectively. Both Fv/Fm and PI indicated that the treated wastewater did not have a significant adverse effect on the photosynthetic efficiency and plant vitality of the crops. Hyperspectral analysis showed higher chlorophyll and nitrogen content in leaves of recycled water-irrigated crops than tap water-irrigated crops. SE had 10.5% dry matter composition (tomato) and Tap had 10.7% (cabbage). Total leaf count of Tap/SE/ME was 86, 111, and 102 for tomato and 37, 40, and 42 for cabbage, respectively. In this study, the use of treated wastewater did not induce any photosynthetic-related or abiotic stress on the crops; instead, it promoted crop growth.


Assuntos
Brassica , Águas Residuárias , Fluorescência , Biomassa , Folhas de Planta , Água , Produtos Agrícolas
10.
Pediatr Cardiol ; 2024 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-38647657

RESUMO

Despite significant advancements in the care of patients with hypoplastic left heart syndrome (HLHS) morbidity and mortality remain high. Postnatal right ventricular dysfunction and tricuspid regurgitation (TR) are associated with worse outcomes in HLHS. We aim to determine if right ventricle functional parameters and TR on fetal echocardiogram are associated with postnatal outcomes in HLHS patients. Retrospective review was performed on all fetuses with HLHS from 2014 to 2022 at our institution. Initial and follow up fetal echocardiogram measurements of right ventricular myocardial performance index (MPI), fractional area change (FAC) and global longitudinal strain (GLS) were retrospectively measured. The presence and severity of TR was recorded from the fetal echocardiogram reports. Postnatal outcomes including transplant-free survival, hospital length of stay > 30 days after initial palliation and need for bidirectional Glenn at < 4 months were reviewed. Forty-three subjects met inclusion criteria. Mean gestational age at presentation was 26.1 ± 5.9 weeks. Nine subjects died and 3 required heart transplantation. Initial fetal echocardiogram MPI was significantly lower (better) (0.36 ± 0.06 vs 0.44 ± 0.11; p = < 0.001) and FAC was significantly higher (better) (45 ± 6% vs 40 ± 8%; p = 0.035) in transplant-free survivors. Fetal right ventricular GLS and presence of mild TR were not associated with postnatal outcome. In fetuses with HLHS, abnormal MPI and right ventricular FAC are associated with decreased transplant-free survival. There was no observed association between GLS and postnatal outcomes. To our knowledge this is the first study examining fetal right ventricular function and GLS in HLHS patients and its link to postnatal outcomes.

11.
BMC Plant Biol ; 24(1): 300, 2024 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-38637728

RESUMO

Cigarette butts (CBs) have become the most ubiquitous form of anthropogenic litter globally. CBs contain various hazardous chemicals that persist in the environment for longer period. These substances are susceptible to leaching into the environment through waterways. The recent study was aimed to evaluate the effects of disposed CBs on the growth and development of Azolla pinnata, an aquatic plant. It was found that after a span of 6 days, the root length, surface area, number of fronds, and photosynthetic efficacy of plant were considerably diminished on the exposure of CBs (concentrations 0 to 40). The exposure of CBs led to a decrease in the FM, FV/F0, and φP0, in contrast, the φD0 increased in response to CBs concentration. Moreover, ABS/CSm, TR0/CSm, and ET0/CSm displayed a negative correlation with CB-induced chemical stress. The performance indices were also decreased (p-value ≤ 0.05) at the highest concentration of CBs. LD50 and LD90 represent the lethal dose, obtained value for LD50 is 20.30 CBs and LD90 is 35.26 CBs through probit analysis. Our results demonstrate that the CBs cause irreversible damage of photosynthetic machinery in plants and also reflect the efficacy of chlorophyll a fluorescence analysis and JIP test for assessing the toxicity of CBs in plants.


Assuntos
Fotossíntese , Produtos do Tabaco , Clorofila A , Fotossíntese/fisiologia , Ecotoxicologia
12.
J Neural Transm (Vienna) ; 131(7): 763-771, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38598100

RESUMO

Each year, 15 million people worldwide suffer from strokes. Consequently, researchers face increasing pressure to develop reliable behavioural tests for assessing functional recovery after a stroke. Our aim was to establish a new motor performance index that can be used to evaluate post-stroke recovery in both young and aged animals. Furthermore, we validate the proposed procedure and recommend the necessary number of animals for experimental stroke studies. Young (n = 20) and aged (n = 27) Sprague-Dawley rats were randomly assigned to receive either sham or stroke surgery. The newly proposed performance index was calculated for the post-stroke acute, subacute and chronic phases. The advantage of using our test over current tests lies in the fact that the newly proposed motor index test evaluates not only the performance of the unaffected side in comparison to the affected one but also assesses overall performance by taking into account speed and coordination. Moreover, it reduces the number of animals needed to achieve a statistical power of 80%. This aspect is particularly crucial when studying aged rodents. Our approach can be used to monitor and assess the effectiveness of stroke therapies in experimental models using aged animals.


Assuntos
Envelhecimento , Modelos Animais de Doenças , Ratos Sprague-Dawley , Animais , Masculino , Envelhecimento/fisiologia , Isquemia Encefálica/fisiopatologia , Isquemia Encefálica/complicações , Ratos , Recuperação de Função Fisiológica/fisiologia , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/fisiopatologia , Atividade Motora/fisiologia
13.
Updates Surg ; 2024 Mar 26.
Artigo em Inglês | MEDLINE | ID: mdl-38530609

RESUMO

Our study aims to investigate the changes in cardiac functions, especially myocardial performance index (MPI), in patients who underwent parathyroidectomy for secondary hyperparathyroidism. Patients who underwent parathyroidectomy for secondary hyperparathyroidism between June 2010 and September 2021 were analyzed retrospectively. The patients were divided into two groups: those who underwent total parathyroidectomy (group 1) and those who underwent subtotal parathyroidectomy (group 2). The groups were compared according to the echocardiogram findings performed in the preoperative period and the postoperative sixth month. In addition, cardiac structure, and systolic and diastolic functions, especially myocardial performance index, were evaluated by echocardiography and Doppler imaging. Thirty-seven patients were examined; 16 (43.2%) underwent total parathyroidectomy, and 21 (56.8%) had subtotal parathyroidectomy performed. Group 1's mean left ventricular end-systolic diameter (LVES) decreased from 2.53 ± 0.57 to 2.35 ± 0.37 cm after parathyroidectomy. In Group 1, the postoperative value of LVES and end-systolic volume decreased significantly compared to the preoperative period (p = 0.042, p = 0.008, respectively). EF increased from 59.25 ± 0.05 to 67.81 ± 4.04. In Group 1, EF and EV postoperatively increased significantly compared to the preoperative period (p = 0.023, p = 0.021, respectively). The mean MPI decreased from 0.45 ± 0.07 to 0.39 ± 0.04 after parathyroidectomy in group 1. In group 2, it decreased from 0.46 ± 0.06 to 0.40 ± 0.04 (p < 0.001). The present study provides an improvement in myocardial functions after parathyroidectomy. While LVES, EF, ejection volume, end-systolic volume, and MPI improved in both groups, the MPI improvement was more evident in the total parathyroidectomy group.

14.
Int Orthop ; 48(5): 1295-1302, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38502337

RESUMO

PURPOSE: Coronal shear fractures of the distal humerus involving the capitellum and trochlea are rare injuries. Internal fixation with headless compression screws provides a stable construct facilitating early mobilisation. Our study aimed to identify the key determinants of both radiological and functional outcomes of patients with distal humerus coronal shear fractures treated with internal fixation. METHODS: A retrospective analysis of 61 patients with distal humerus coronal shear fractures who were treated surgically was done. Demographics, fracture morphology, time to surgery, operative details such as surgical approach and implant used, quality of reduction, time to union, and associated complications from hospital records. Radiological outcomes were assessed using plain radiographs, and the functional outcomes were by Oxford Elbow Score (OES) and Mayo Elbow Performance Index (MEPI). RESULTS: Patients with anatomical reduction of the fracture had better functional outcomes and range of motion. The presence of posterior comminution of capitellum resulted in poorer outcomes (p = 0.03). Delayed presentation did not alter the outcome when the anatomical reduction was achieved. Myositis ossificans was noted in nine patients and non-union in five patients. Two patients developed avascular necrosis of the capitellum and arthritis of the elbow joint. CONCLUSION: Anatomical reduction and posterior comminution are the two key determinants of the functional outcome in these coronal shear fractures of the distal humerus. Early mobilisation following a stable fixation is crucial in achieving a good outcome.


Assuntos
Articulação do Cotovelo , Fraturas Cominutivas , Fraturas do Úmero , Humanos , Articulação do Cotovelo/diagnóstico por imagem , Articulação do Cotovelo/cirurgia , Estudos Retrospectivos , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/cirurgia , Úmero , Radiografia , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/métodos , Fraturas Cominutivas/cirurgia , Amplitude de Movimento Articular , Resultado do Tratamento
15.
Sci Rep ; 14(1): 5694, 2024 03 08.
Artigo em Inglês | MEDLINE | ID: mdl-38459084

RESUMO

Besides achieving high quality products, statistical techniques are applied in many fields associated with health such as medicine, biology and etc. Adhering to the quality performance of an item to the desired level is a very important issue in various fields. Process capability indices play a vital role in evaluating the performance of an item. In this paper, the larger-the-better process capability index for the three-parameter Omega model based on progressive type-II censoring sample is calculated. On the basis of progressive type-II censoring the statistical inference about process capability index is carried out through the maximum likelihood. Also, the confidence interval is proposed and the hypothesis test for estimating the lifetime performance of products. Gibbs within Metropolis-Hasting samplers procedure is used for performing Markov Chain Monte Carlo (MCMC) technique to achieve Bayes estimation for unknown parameters. Simulation study is calculated to show that Omega distribution's performance is more effective. At the end of this paper, there are two real-life applications, one of them is about high-performance liquid chromatography (HPLC) data of blood samples from organ transplant recipients. The other application is about real-life data of ball bearing data. These applications are used to illustrate the importance of Omega distribution in lifetime data analysis.


Assuntos
Teorema de Bayes , Simulação por Computador , Cadeias de Markov , Método de Monte Carlo
16.
Artigo em Alemão | MEDLINE | ID: mdl-38345648

RESUMO

BACKGROUND: The relevance of septic cardiomyopathy is frequently underestimated due to the complexity of the pattern of cardiac injury and the corresponding difficulties in quantifying the degree of functional impairment. AIM: Account of the methods for diagnosis and severity classification of septic cardiomyopathy. METHODS: Literature review and analysis of the main findings. RESULTS: Septic cardiomyopathy is characterized by both systolic and diastolic impairment of not only the left, but also the right ventricle, as well as by sinus-tachycardiomyopathy (≥ 90-95 beats/min) of variable degree. Sepsis-related organ failure assessment (SOFA) score, left ventricular ejection fraction (LVEF), ECG and cardiac biomarkers do not help in grading severity of septic cardiomyopathy. For that purpose either a sophisticated echocardiography diagnosis is mandatory, or the measurement of those global heart function parameters which take into account the dependency of cardiac output on afterload, in view of the pronounced vasodilatation in sepsis and septic shock, is needed. A suitable parameter on the basis of cardiac output measurement is afterload-related cardiac performance (ACP), which gives the percentage of cardiac output in a septic patient related to the cardiac output a healthy heart pumps when challenged by a fall in systemic vascular resistance to the same extent. The calculation of ACP shows that at least one in two septic patients suffers from impaired heart function and that mortality increases as severity increases. CONCLUSION: Simple parameters like LVEF are not apt for diagnosis nor for disease severity classification of septic cardiomyopathy. For that purpose either sophisticated echocardiography techniques or load-independent parameters-best validated-ACP measurements are appropriate.

17.
J Ultrasound Med ; 43(5): 851-861, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38213069

RESUMO

OBJECTIVES: To investigate whether fetal cardiac function is affected by underlying heart disease in pregnant women. METHODS: A total of 100 pregnant women who were ≥34 gestational weeks were included in the study, 40 in the maternal heart disease (MHD) group diagnosed with heart disease and 60 in the control group. All cardiac diseases in pregnant women were diagnosed preconceptionally and categorized according to the New York Heart Association (NYHA) classification system. Fetal cardiac functions of study groups were evaluated by M-mode, color tissue Doppler imaging (c-TDI), and pulsed wave Doppler. RESULTS: Tricuspid annular plane systolic excursion and myocardial performance index (MPI) values were significantly higher and isovolumetric relaxation time was prolonged in the MHD group. The MPI value was found higher in MHD group with NYHA Class II compared to those with NYHA Class I. No significant change in any of the fetal tricuspid annular peak velocity values measured by c-TDI in the MHD group. There were no differences in fetal cardiac functions and perinatal outcomes between pregnant women with acquired and congenital heart diseases. Patients in NYHA Class II had lower birth weight, 1st and 5th minute APGAR scores, and higher neonatal intensive care unit admission rates. CONCLUSIONS: Underlying heart diseases in pregnant women can cause alterations in the systolic and diastolic function of the fetal heart. High fetal MPI values detected in cardiac patients may indicate that cardiac pathologies during pregnancy affect fetal cardiac globular myocardial function. Cardiac pathologies that progress with restricted physical activity may cause changes in fetal cardiac function and may be associated with adverse perinatal outcomes.


Assuntos
Cardiopatias , Recém-Nascido , Humanos , Gravidez , Feminino , Cardiopatias/complicações , Cardiopatias/diagnóstico por imagem , Coração Fetal/diagnóstico por imagem , Sístole , Estudos Prospectivos , Diástole , Ultrassonografia Pré-Natal/métodos
18.
Environ Sci Pollut Res Int ; 31(9): 13003-13025, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38240973

RESUMO

An experimental investigation was conducted to determine the effectiveness of roadside trees for removing dust and the effects of dust load on the physiology and micromorphology of the foliage. The present study was conducted near an open coal mining complex situated in Singrauli, Madhya Pradesh, India, to assess the air pollution tolerance index (APTI), anticipated performance index (API), dust capturing capacity (DCC), and leaf morphology of trees and shrubs growing around the coal fields. Results showed that Azadirachta indica, Mangifera indica, Ficus religiosa, Ailanthus excelsa, and Ficus benghalensis were the most tolerant species towards air pollution (high APTI scores), while plants like Calotropis gigantea, Lantana camara, and Tectona grandis were proven to be bio-indicator species. Butea monosperma, Ficus benghalensis, Alstonia scholaris, and Terminalia arjuna were plant species with the highest DCC. Two-way ANOVA showed significant differences site-wise and season-wise in the biochemical parameters of APTI and a considerable difference site-wise with respect to dust capturing capacity. Correlation and regression analyses revealed a very high positive correlation between APTI and ascorbic acid value. The study recommends suitable plant species to manage rising air pollution in the coal mine and nearby areas apart from suggesting the development of a green belt.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Árvores , Poluentes Atmosféricos/análise , Monitoramento Ambiental/métodos , Clorofila/análise , Poluição do Ar/análise , Poeira/análise , Plantas , Folhas de Planta/química , Índia , Carvão Mineral/análise
19.
J Environ Manage ; 352: 120117, 2024 Feb 14.
Artigo em Inglês | MEDLINE | ID: mdl-38237336

RESUMO

With China being the world's largest emitter of greenhouse gases and its aviation sector burgeoning, the environmental performance of Chinese airlines has global significance. Amidst rising demands for eco-friendly practices from both customers and regulators, the interplay between airport infrastructure and environmental performance becomes pivotal. This research offers an innovative methodology to gauge the environmental performance of Chinese airlines, emphasizing the distance traveled between airports using weighted additive utility functions. Leveraging neural networks, the study investigates the impact of various airport infrastructural characteristics on environmental performance. Noteworthy findings indicate that ground control measures, automatic information services at origin airports, surface concrete on runways at both ends, and a centerline lighting system in destination airports positively influence environmental performance. In contrast, longer and wider runways at origin airports, increased distances to control towers, and asphalt runways at destination airports adversely affect it. These insights not only underscore the importance of strategic infrastructure enhancements for reducing carbon footprints but also hold profound policy implications. As global climate change remains at the forefront, fostering sustainable airport infrastructure in China can significantly contribute to worldwide mitigation efforts.


Assuntos
Poluentes Atmosféricos , Aviação , Poluentes Ambientais , Gases de Efeito Estufa , Aeroportos , Poluentes Atmosféricos/análise
20.
Echocardiography ; 41(1): e15736, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38284669

RESUMO

OBJECTIVE: To evaluate both short and mid-term effects of maternal COVID-19 on cardiac functions of fetuses and children. METHODS: The present case-control study was conducted on 36 pregnant women who had COVID-19 infection in the second trimester of pregnancy and 30 pregnant women as healthy controls. Fetal, neonatal, and infant cardiac functions were compared between the groups. Assessment of fetal cardiac functions were performed in the last trimester of the pregnancy at least 6 weeks after the recovery of infection. The first postnatal echo was performed within the first 2 weeks and the follow-up (second) echo was performed in the 6-8 weeks of life. RESULTS: The demographic data were similar between groups. Interventricular septum and left ventricular posterior wall end-diastolic dimensions were significantly higher in the study group in both fetal, neonatal, and infant periods. Impaired diastolic functions of right and left ventricles were detected and myocardial performance indexes with tissue doppler imaging of both lateral walls and septum were significantly higher than controls at all periods. CONCLUSION: Maternal COVID-19 seems to have a global impact on the cardiac functions of babies in the short and mid-term periods after maternal recovery.


Assuntos
COVID-19 , Ecocardiografia Doppler , Recém-Nascido , Lactente , Criança , Gravidez , Feminino , Humanos , Ecocardiografia Doppler/métodos , Coração Fetal/diagnóstico por imagem , Ventrículos do Coração/diagnóstico por imagem , Terceiro Trimestre da Gravidez , Ultrassonografia Pré-Natal/métodos
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