Transitional photoperiod induces a mania-like behavior in male mice.

This study aimed to investigate the behavioral responses and circadian rhythms of mice to both rapid and gradual increases in photoperiod, mimicking the transition from winter to summer, which is associated with a heightened prevalence of hospitalizations for mania and suicidal behavior. Behavioral tests were performed in C57BL/6 male mice exposed to a transitional photoperiod, from short to long durations. To determine if circadian rhythms are affected, we measured spontaneous locomotor activity and body temperature. Mice exhibited heightened exploratory and risk-taking behaviors compared with equatorial and static long (16:8 h of light-dark cycle for several days) groups. These behaviors were prevented by lithium. Spontaneous locomotor activity and body temperature rhythms persisted and were effectively synchronized; however, the relative amplitude of activity and interdaily stability were diminished. Additionally, the animals displayed increased activity during the light phase. Photoperiodic transition modulates behavior and circadian rhythms, mirroring certain features observed in bipolar disorder patients. This study introduces an animal model for investigating mania-like behavior induced by photoperiodic changes, offering potential insights for suicide prevention strategies and the management of mood disorders.

Percepción de riesgo sobre el consumo de drogas en estudiantes universitarios

Introducción: El consumo de drogas es un problema de salud que se presenta con mayor frecuencia en la población joven, pues su prevalencia aumenta cada día. En la actualidad existe preocupación sobre la percepción de riesgo del consumo de drogas en estudiantes universitarios. Objetivo: Describir la percepción de riesgo sobre el consumo de drogas en estudiantes universitarios de la provincia Manabí en Ecuador. Métodos: Investigación descriptiva y transversal; universo de 787 estudiantes universitarios de la provincia Manabí en Ecuador. La muestra quedó conformada por 259 estudiantes. Se utilizó la encuesta como técnica de recolección de datos. Como instrumento de investigación se utilizaron las encuestas escolares sobre el uso indebido de drogas de la oficina de las Naciones Unidas contra la droga y el delito. Se utilizó la estadística descriptiva para el procesamiento de los datos. Resultados: Se obtuvo una media de edad de 22,37 años, predominio del sexo femenino (65,25 %) y de estudiantes que consumen algún tipo de droga (79,92 %). El 91,30 % refirió consumo de drogas lícitas (tabaco 43,63 % y alcohol 61,39 %); el 31,26 % consumían drogas medicamentosas y el 23,29 % drogas ilícitas; de ellos, el 85,42 % refirió consumo de marihuana. El 32,04 % tenía una percepción baja sobre el riesgo de consumo de drogas. Conclusiones: En el grupo de estudiantes universitarios de la provincia Manabí que son investigados, existe un aumento del consumo de drogas lícitas, medicamentosas e ilícitas debido a una percepción deficiente del riesgo de consumo de estas sustancias.

Introduction: Drug use is a health problem that occurs more frequently in the young population; its prevalence increases every day. Currently, there is concern about the perception of risk of drug use in university students. Objective: Describe the risk perception of drug consumption in university students from the Manabí province in Ecuador. Methods: Descriptive and cross-sectional research; universe of 787 university students from the Manabí province in Ecuador. The sample was made up of 259 students. The survey was used as a data collection technique. The School Surveys on Drug Abuse from the United Nations Office on Drugs and Crime were used as a research instrument. Descriptive statistics were used to process the data. Results: An average age of 22.37 years was obtained, predominance of the female sex (65.25%) and students who consume some type of drug (79.92%). 91.30% reported consumption of legal drugs (tobacco 43.63% and alcohol 61.39%); 31.26% used medicinal drugs and 23.29% used illicit drugs; Of them, 85.42% reported marijuana use. 32.04% had a low perception of the risk of drug use. Conclusions: In the group of university students from the Manabí province who are investigated, there is an increase in the consumption of licit, medicinal and illicit drugs due to a poor perception of the risk of consumption of these substances.

Reappraising the role of dopamine in adolescent risk-taking behavior.

Adolescence is characterized by increased risk-taking, which is often ascribed to developmental changes in dopaminergic signaling. Popular models propose that these behaviors are caused by dopamine-induced hypersensitivity to rewards, which overrides adolescents' immature self-control mechanisms. However, these models are often based on oversimplified notions about the workings and functions of dopamine. Here we discuss the relationship between changes in the dopaminergic system and adolescent behavior in light of current theories/models about the functions of dopamine. We show that dopamine is linked to learning, adaptive decision-making under uncertainty, and increased motivation to work for rewards. Thus, changes in the dopaminergic system contribute to the maturation of cognitive control through various mechanisms, contrary to the false dichotomy between reward processing and self-control. Finally, we note that dopamine interacts with a number of other neuromodulator systems, which also change during adolescence, but that have been largely ignored in the field of adolescent development. A full understanding of adolescent behavior will require these neurochemicals and their interactions with dopamine to be taken into account.

Decision-making under risk and theory of mind in adolescent offenders in provisional deprivation of liberty.

INTRODUCTION: Delinquent behaviors are risky behaviors that increase during puberty and reach their highest peak in late adolescence. It has been proposed that poor decision-making and theory of mind (ToM) are key cognitive processes implicated with delinquency during adolescence, affecting evaluation of risks and impairing appreciation of social norms. Nevertheless, it is not yet clear whether adolescent offenders who are subjected to provisional deprivation of liberty due to conflict with the law (adolescents in conflict with the law [ACL]) might, in fact, present a specific profile with regard to these cognitive processes. OBJECTIVES: To assess deliberative decision-making and ToM among adolescents in conflict with the law and adolescents not in conflict with the law. METHODS: The sample comprised 62 participants: ACL (n = 29) and a control group (CG) (n = 33). ToM was assessed with the Reading the Mind in the Eyes Test (RMET) and decision-making was assessed with the Columbia Card Task (CCT). Substance use, callous-unemotional traits, childhood maltreatment, and intelligence quotient (IQ) were also assessed. RESULTS: ACL had more ToM errors for negative mental states in comparison to CG, but not for error rates concerning neutral and positive mental states. With regards to decision-making, our results suggest that ACL group members did not vary their behavior based on the available information and that the risk information had an opposite effect on the number of cards chosen (risk-taking behavior) when compared to CG. CONCLUSION: These findings have important implications for development of interventions for these adolescents, suggesting that they tend to learn little from negative outcomes and have reduced capacity to process negative emotions.

Impact of Attention Deficit Hyperactivity Disorder on Entrepreneurial Behavior: A Neurobiological Approach / Impacto del Trastorno por Déficit de Atención e Hiperactividad en el Comportamiento Empresarial: Un enfoque neurobiológico

The objective of this study is to determine the relationship between Attention Deficit Hyperactivity Disorder (ADHD) and entrepreneurial behavior, especially in characteristics such as risk-taking, creativity, and decision-making. Three groups of ten individuals (5 women; age 36.3 ± 14.0) were selected using social media platforms: one group with ADHD (four participants), one group of entrepreneurs (three participants), and one control group without ADHD or entrepreneurial ex-perience (three participants). 10-question interviews, tailored to their respective profiles, were conducted individually via Zoom. After interviews transcriptions, significant statements were extracted for data analysis. Participants were also instructed to play the Iowa Gambling Task (IGT) from an online platform to as-sess decision-making and risk-taking. Individual data were compiled, compared and statistically processed with Microsoft Excel. As results, comparing interview statements between individuals with ADHD, entrepreneurs, and the control group, in terms of risk-taking, attention, and creativity showed that individuals with ADHD can bring unique traits and skills to entrepreneurship, while entrepreneurs have specific strategies for managing distractions and maintaining focus. The control group emphasizes organization and analysis rather than creativity. The findings from the IGT suggested that people with ADHD may exhibit impulsive tendencies and difficulty evaluating the long-term consequences of their actions. Entrepreneurs were willing to take calculated risks to seize opportunities and achieve their goals, and they were also aware of the need to limit risk and make prudent decisions to protect their investments. The control group highlighted the individual differences in risk-taking in randomly selected individuals, without any special condition. They showed a certain caution in opting for low-risk choices. In conclusion, the study underscores the importance of considering individual and contextual factors in decision-making processes, incorporating neurobiological aspects of ADHD. Although available data did not directly examine the influence of these factors on entrepreneurship success, it highlights the significance of understanding the complex influences involved in decision-making.

El objetivo de este estudio es determinar la relación entre el Trastorno por Déficit de Atención con Hiperactividad (TDAH) y el comportamiento emprendedor, especialmente en características como la asunción de riesgos, la creatividad y la toma de decisiones. Se seleccionaron tres grupos de diez individuos (5 mujeres; edad 36,3 ± 14,0) utilizando plataformas de medios sociales: un grupo con TDAH (cuatro participantes), un grupo de emprendedores (tres participantes) y un grupo de control sin TDAH ni experiencia emprendedora (tres participantes). Las entrevistas de 10 preguntas, adaptadas a sus respectivos perfiles, se realizaron individualmente a través de Zoom. Tras la transcripción de las entrevistas, se extrajeron las afirmaciones significativas para el análisis de los datos. También se indicó a los participantes que jugaran a la Iowa Gambling Task (IGT) desde una plataforma en línea para evaluar la toma de decisiones y la asunción de riesgos. Los datos individuales se recopilaron, compararon y procesaron estadísticamente con Microsoft Excel. Como resultados, la comparación de las declaraciones de las entrevistas entre individuos con TDAH, emprendedores y el grupo de control, en términos de asunción de riesgos, atención y creatividad, mostró que los individuos con TDAH pueden aportar rasgos y habilidades únicos a la iniciativa empresarial, mientras que los emprendedores tienen estrategias específicas para gestionar las distracciones y mantener la concentración. El grupo de control pone más énfasis en la organización y el análisis que en la creatividad. Los resultados del IGT sugirieron que las personas con TDAH pueden mostrar tendencias impulsivas y dificultad para evaluar las consecuencias a largo plazo de sus acciones. Los empre-sarios estaban dispuestos a asumir riesgos calculados para aprovechar las oportunidades y alcanzar sus objetivos, y también eran conscientes de la necesidad de limitar el riesgo y tomar decisiones prudentes para proteger sus inversiones. El grupo de control puso de manifiesto las diferencias individuales en la asunción de riesgos en individuos seleccionados al azar, sin ninguna condición especial. Mostraron cierta cautela a la hora de optar por opciones de bajo riesgo. En conclusión, el estudio subraya la importancia de considerar los factores individuales y contextuales en los procesos de toma de decisiones, incorporando los aspectos neurobio-lógicos del TDAH. Aunque los datos disponibles no examinaron directamente la influencia de estos factores en el éxito empresarial, pone de relieve la importancia de comprender las complejas influencias que intervienen en la toma de decisiones.

Tradução, adaptação e validação transcultural para o português brasileiro do questionário de Avaliação da Proteção Auditiva (APA) / Translation, adaptation, and cross-cultural validation into Brazilian portuguese of the hearing protection assessment questionnaire (HPA)

RESUMO Objetivo O objetivo do presente estudo foi traduzir, adaptar e validar transculturalmente a versão para língua portuguesa brasileira do questionário Hearing Protection Assessment Questionnaire (HPA). Método O instrumento original, desenvolvido na língua inglesa, buscou avaliar as barreiras e suportes relacionados ao uso dos dispositivos de proteção auditiva (DPA), assim como o conhecimento, hábitos e atitudes dos trabalhadores frente ao ruído ocupacional. A tradução, adaptação e validação transcultural do questionário foi composta de cinco etapas: Tradução do questionário do inglês para o português; 2) Processo inverso de tradução do português para o inglês; 3) Análise do instrumento por três especialistas na área; 4) Pré-teste do questionário com 10 trabalhadores; 5) Aplicação do instrumento em 509 trabalhadores de uma indústria frigorífica após o exame admissional. Resultados os resultados indicam a validade de construção e conteúdo da versão em Português Brasileiro para o seu uso com uma população trabalhadora e a consistência interna do mesmo. Conclusão Este estudo resultou na tradução, na adaptação cultural e validação do questionário Hearing Protection Assessment Questionnaire (HPA) com a finalidade de ser usado para avaliar o uso de proteção auditiva individual em âmbito ocupacional, denominado Questionário de Avaliação da Proteção Auditiva (APA).

ABSTRACT Purpose The aim of the present study is to translate, adapt, and cross-culturally validate the Brazilian Portuguese version of the questionnaire Hearing Protection Assessment Questionnaire (HPA). Methods The original instrument, developed in English, seeks to assess barriers and supports related to the use of hearing protection devices (HPD), as well as workers' knowledge, habits and attitudes towards occupational noise. The translation, adaptation, and cross-cultural validation of the questionnaire consisted of five steps: Translation of the questionnaire from English to Portuguese; 2) Reverse translation from Portuguese to English; 3) Analysis of the instrument by three experts in the field; 4) Pre-test of the questionnaire with ten workers; 5) Application of the instrument to 509 workers in a meatpacking industry after the pre-employment medical exam. Results The results indicate the construction and content validity of the Brazilian Portuguese version for use with a working population and its internal consistency. Conclusion This study resulted in the translation, cultural adaptation, and validation of the Hearing Protection Assessment Questionnaire (HPA), in order to be used to assess the use of individual hearing protection in the occupational field, called Hearing Protection Assessment Questionnaire (HPA).

Significados de exposição ao HIV/AIDS atribuídos por mulheres que professam religiões afro-brasileiras / Meanings of exposure to HIV/AIDS attributed by women who profess Afro-Brazilian religions / Significados de exposición al VIH/SIDA atribuidos por mujeres que profesan religiones afrobrasileñas

Objetivo: conhecer os significados atribuídos por mulheres que professam religiões afro-brasileiras à exposição ao HIV/AIDS. Método: estudo interpretativo, qualitativo, com amostragem por meio da técnica de bola de neve, selecionando 21 mulheres que professam religiões afro-brasileiras, em sete grupos amostrais. Coleta deda dados realizada entre julho de 2019 e outubro de 2020, por meio de entrevistas semiestruturadas, em parque urbano público em São Paulo e, virtualmente. Dados analisados segundo o Interacionismo Simbólico e a Grounded Theory. Resultados: participaram mulheres entre 18 e 70 anos, a maioria casada, com pós-graduação completa, frequentando, pelo menos uma vez na semana, a instituição religiosa, há mais de 5 anos. As participantes significam exposição ao HIV/AIDS como falta de autocuidado, não ter cuidado com o corpo, morada de orixás, relacionando com prevenção, discernimento e respeito, cuja visão conservadora enfoca o outro. Conclusão: os significados atribuídos à exposição ao HIV/AIDS estão fortemente influenciados pelas crenças religiosas, salientando a exposição dos outros.

Objective: to discover the meanings attributed by women who profess Afro-Brazilian religions to exposure to HIV/AIDS. Method: in this interpretive, qualitative study, using the snowball technique, 21 women who profess Afro-Brazilian religions were selected in 7 sample groups. Data were collected from July 2019 to October 2020 by semi-structured interviews in a public urban park in São Paulo and virtually by Google Meet, and analyzed by Symbolic Interactionism and Grounded Theory, with ATLAS.ti9 software. Results: participants were 18 to 70 years old, most married, with complete postgraduate studies, and had attended the religious institution at least once a week for more than 5 years. The participants attributed meaning to exposure to HIV/AIDS as lack of self-care, lack of care for the body, the home of orixá deities, and related it to prevention, discernment and respect, in a conservative view focusing on others. Conclusion: the meanings attributed to exposure to HIV/AIDS were strongly influenced by religious beliefs and emphasized the exposure of others.

Objetivo: conocer los significados atribuidos por mujeres que profesan religiones afrobrasileñas a la exposición al VIH/SIDA. Método: estudio interpretativo, cualitativo, utilizando para la muestra el método de bola de nieve, seleccionando 21 mujeres que profesan religiones afrobrasileñas, en siete grupos de muestra. La recolección de datos tuvo lugar entre julio/2019 y octubre/2020, a través de entrevistas semiestructuradas, en un parque público urbano de São Paulo y también virtualmente. Los datos se analizaron según el Interaccionismo Simbólico y la Grounded Theory. Resultados: participaron mujeres con edades entre 18 y 70 años, la mayoría casada, con estudios de posgrado completo, asistiendo a la institución religiosa al menos una vez por semana desde hace más de 5 años. Las participantes entienden la exposición al VIH/SIDA como falta de autocuidado, descuido del cuerpo, hogar de los orixás, comparado a la prevención, al discernimiento y al respeto, cuya mirada conservadora se enfoca en el otro. Conclusión: los significados atribuidos a la exposición al VIH/SIDA están fuertemente influenciados por las creencias religiosas, destacando la exposición de los demás.

Preventive measures against the COVID-19 pandemic in Mexico: A cross-sectional study.

Introduction: Understanding how Mexicans behave during the pandemic could present a complete picture of the phenomenon in our country and provide better management of it. Objective: This study aimed to analyze the Mexican population's behavior and preventive measures. Methods: This was a cross-sectional study in which a total of 4,004 participants from the general population responded to the survey. Results: Almost 99% of the participants mentioned knowing the symptoms of COVID-19. Although 77.5% of participants considered that they followed proper social distancing measures, 60% of them mentioned that they knew at least six individuals who did not follow social distancing measures. Furthermore, 96.2% of participants reported using preventive measures at least 50% of the time. Only 51.3% used a certified mask. Conclusion: The COVID-19 pandemic outcomes in Mexico are the result of multiple negative factors, such as high rates of comorbidities, high number of people living together at home, many people breaking social isolation, and most of the population using non-certified preventive measures that may not be effective enough.

The Tower Building Task: A Behavioral Tool to Evaluate Recreational Risk-Taking.

Risk-taking is a fundamental aspect of life spanning diverse contexts. Despite many tests being readily available, the behavioral assessment of risk propensity in recreational contexts, where decisions are not necessarily motivated by monetary gains or losses, is not well represented. As the tower building task (TBT) shares features of recreational activities, we evaluated whether it could assess risk-taking in this type of scenario. In the TBT, participants use standard-size wooden blocks to build the tallest tower they can within a 10 min period. In the current study we (i) examined methodological modifications to the task to either promote or reduce risky behavior and (ii) tested possible associations between the TBT scores and those of two commonly used risk-taking evaluations: The Balloon Analogue Risk Task (BART) and the Sensation Seeking Scale (SSS). We found that limiting the number of permitted collapses decreased the willingness to take risks, whereas challenging participants to exceed a "record" height increased risk-taking. TBT scores of one of the conditions correlated with scores of the BART and the SSS, particularly with the subscale addressing recreational activities. These findings suggest that the TBT offers a potentially useful means of evaluating risk-taking behaviors akin to those of the recreational domain.

Individual's Reproductive Strategies Moderates the Association Between Facial Width-to-Height and Risk-Taking Propensity.

Previous research has yielded mixed findings on the relationship between facial width-to-height ratio (fWHR), an androgen-dependent feature, and risk-taking propensity. We argue that mixed findings might result from overlooked variables. Given that risk-taking propensity might be ultimately linked to a search for mating opportunities, we analyze if reproductive strategies moderate the relationship between fWHR and risk-taking propensity. Our results, obtained from a sample of 434 male participants, show a positive association between fWHR and recreational and social risk-taking only for men who are more motivated to focus on mating effort over offspring survival. This finding aligns with research arguing that risk-taking may be a mating strategy since being social and recreational risk-prone might illustrate physical and psychological qualities and improve one's ability to attract mates. Our results support the notion that risk-taking might be a domain-specific construct. Overall, our research is in line with recent findings suggesting that the impact of testosterone exposure on risk-taking propensity is best understood when considering the role of contextual variables. Consequently, we add to previous research that studies related to risk-taking propensity should account for reproductive strategies.

Covariation among behavioral traits and hatching time in zebrafish.

Individuals of the same population differ in several ways. For instance, in fish populations, individuals who hatch earlier show more active behavior and are more explorative than those that hatch later, which is a characteristic of the behavioral personality type. One of the aspects relevant to this theory is the consistency of behavioral differences between contexts and over time. Thus, the present study evaluated the relationship between hatching time and behavioral consistency in two ontogenetic stages: juvenile and adult, and different contexts in zebrafish (Danio rerio). For this, the animals were separated according to hatching time into early-hatching (EH) and late-hatching (LH) fish and tested in an anxiety-like context (black-white paradigm) at the 30th-day post fertilization (dpf) and the 120th dpf. The animals were also tested in a novel tank paradigm and novel object paradigm to access explorativeness and boldness, respectively. In the black-white test, EH animals presented shorter latency to enter the white area and stayed longer in the black area than LH animals. The EH individuals were more explorative and bold in the novel tank and novel object tests and showed less anxiety-like behavior than the LH. In general, the results obtained suggest that hatching time may indicate consistent differences for zebrafish behavioral profiles.

Decision-making under risk and theory of mind in adolescent offenders in provisional deprivation of liberty

Abstract Introduction Delinquent behaviors are risky behaviors that increase during puberty and reach their highest peak in late adolescence. It has been proposed that poor decision-making and theory of mind (ToM) are key cognitive processes implicated with delinquency during adolescence, affecting evaluation of risks and impairing appreciation of social norms. Nevertheless, it is not yet clear whether adolescent offenders who are subjected to provisional deprivation of liberty due to conflict with the law (adolescents in conflict with the law [ACL]) might, in fact, present a specific profile with regard to these cognitive processes. Objectives To assess deliberative decision-making and ToM among adolescents in conflict with the law and adolescents not in conflict with the law. Methods The sample comprised 62 participants: ACL (n = 29) and a control group (CG) (n = 33). ToM was assessed with the Reading the Mind in the Eyes Test (RMET) and decision-making was assessed with the Columbia Card Task (CCT). Substance use, callous-unemotional traits, childhood maltreatment, and intelligence quotient (IQ) were also assessed. Results ACL had more ToM errors for negative mental states in comparison to CG, but not for error rates concerning neutral and positive mental states. With regards to decision-making, our results suggest that ACL group members did not vary their behavior based on the available information and that the risk information had an opposite effect on the number of cards chosen (risk-taking behavior) when compared to CG. Conclusion These findings have important implications for development of interventions for these adolescents, suggesting that they tend to learn little from negative outcomes and have reduced capacity to process negative emotions.

Fatores associados ao óbito por HIV/Aids / Factores asociados al fallecimiento por VIH/Sida / Factors associated with death due to HIV/AIDS

Resumo Objetivo Analisar os fatores associados ao óbito em pessoas com HIV/Aids. Método Estudo epidemiológico e analítico, realizado a partir das notificações de HIV/Aids do estado de Mato Grosso do Sul, no período de 2009 à 2018. Os dados foram analisados por meio de estatística descritiva, análise de sobrevida via método de Kaplan-Meier e regressão de Cox. Resultados Foram analisadas 8.712 notificações, com taxa de sobrevida de 86% ao longo dos 10 anos. Os fatores associados ao óbito foram:sexo masculino (=1,22; p=0,006), cor da pele parda (=1,30; p=0,012), oito anos ou menos de estudo (=1,57; p=0,000), e possível transmissão sexual mediante relação com mulheres (=2,72; p=0,000) ou com ambos - homens e mulheres (=2,24; p=0,002) e utilização de drogas injetáveis (=2,57; p=0,016). Conclusão Características sociais, culturais e comportamentais podem contribuir para redução da sobrevida das pessoas com HIV/Aids. Esses fatores sinalizam especificidades a serem consideradas no planejamento assistencial e monitoramento dos casos, em especial no que concerne à necessidade de busca ativa, monitoramento contínuo, além de intervenções que envolvam mudanças de comportamento.

Resumen Objetivo Analizar los factores asociados al fallecimiento de personas con VIH/Sida. Método Estudio epidemiológico y analítico, realizado a partir de las notificaciones de VIH/Sida en el estado de Mato Grosso do Sul, en el período de 2009 a 2018. El análisis de los datos se realizó por medio de estadística descriptiva, análisis de sobrevida por el método de Kaplan-Meier y de regresión de Cox. Resultados Se analizaron 8.712 notificaciones, con un índice de sobrevida del 86 % a lo largo de los 10 años. Los factores asociados al fallecimiento fueron: sexo masculino (=1,22; p=0,006), color de piel parda (=1,30; p=0,012), ocho años o menos de estudio (=1,57; p=0,000), y posible transmisión sexual mediante relación con mujeres (=2,72; p=0,000) o con ambos, hombres y mujeres (=2,24; p=0,002), y uso de drogas inyectables (=2,57; p=0,016). Conclusión Características sociales, culturales y de comportamiento pueden contribuir para la reducción de la sobrevida de las personas con VIH/Sida. Esos factores señalan especificidades que se deben considerar en la planificación asistencial y en el monitoreo de los casos, en especial en lo que atañe a la necesidad de la búsqueda activa, el monitoreo continuo e intervenciones que incluyan cambios de comportamiento.

Abstract Objective To analyze the factors associated with death in people with HIV/AIDS. Method This is an epidemiological and analytical study, carried out from the HIV/AIDS notifications of the state of Mato Grosso do Sul, from 2009 to 2018. Data were analyzed using descriptive statistics, Kaplan-Meier survival analysis and Cox regression. Results A total of 8,712 notifications were analyzed, with a survival rate of 86% over the 10 years. Factors associated with death were: males (=1.22; p=0.006), brown skin color (=1.30; p=0.012), eight years or less of study (=1.57; p=0.000), and possible sexual transmission through intercourse with women (=2.72; p=0.000) or with both men and women (=2.24; p=0.002) and use of injectable drugs (=2.57; p=0.016). Conclusion Social, cultural and behavioral characteristics may contribute to reduce the survival of people with HIV/AIDS. These factors indicate specificities to be considered in care planning and monitoring of cases, especially with regard to the need for an active search, continuous monitoring, in addition to interventions that involve changes in behavior.

Educação sexual e vulnerabilidade de usuários de aplicativos, comparações a partir da orientação sexual / Educación sexual y vulnerabilidad de usuarios de aplicaciones, comparaciones a partir de la orientación sexual / Sex education and vulnerability of application users, comparisons based on sexual orientation

Resumo Objetivo Analisar a educação sexual, comportamentos de risco e atitudes de universitários usuários de aplicativos de encontros, considerando a orientação sexual. Métodos Trata-se de um estudo de natureza quantitativa, transversal e descritivo, com uma amostra não probabilística de conveniência, constituída por 359 universitários da região norte do Brasil. Utilizou-se um questionário com informações sobre dados sociodemográficos, uso de aplicativos de encontros, fontes de informações sobre sexo seguro, comportamentos de risco e atitudes. Foram realizadas análises bivariadas e análise de variância com testes post-hoc de Bonferroni. Resultados Homossexuais (92,3%) e bissexuais (84,9%) reportaram o uso de aplicativos e tiveram encontro com parceiro casual (p<0,05). O Tinder foi o aplicativo acessado por 93,58% dos usuários. Não houve diferença para a prática sexual, sexo desprotegido e múltiplos parceiros sexuais. Informações sobre sexo seguro e infecções sexualmente transmissíveis por meio dos aplicativos foi reportada por homossexuais (61,1%) (p<0,05). Bissexuais (22,2%) vivenciaram a educação sexual nos eventos científicos e heterossexuais (38,2%) recorreram aos amigos universitários (p<0,05). Homossexuais (88,9%) acessaram o serviço do Centro de Testagem e Aconselhamento e 72,4% realizaram a testagem para infecções sexualmente transmissíveis após a prática sexual com parceiro casual (p<0,05). As atitudes positivas para a saúde sexual foram observadas nos heterossexuais não usuários de aplicativos de encontros. Conclusão A vulnerabilidade dos usuários de aplicativos de encontros não esteve associada com a orientação sexual. Intervenções por meio da educação sexual que estimulem o autoconhecimento e os riscos da prática sexual desprotegida são requeridas frente ao acesso às tecnologias para encontros casuais.

Resumen Objetivo Analizar la educación sexual, comportamientos de riesgo y actitudes de estudiantes universitarios usuarios de aplicaciones de citas, considerando la orientación sexual. Métodos Se trata de un estudio de naturaleza cuantitativa, transversal y descriptiva, con una muestra no probabilística de conveniencia, constituida por 359 estudiantes universitarios de la región norte de Brasil. Se utilizó un cuestionario con información sobre datos sociodemográficos, uso de aplicaciones de citas, fuentes de información sobre sexo seguro, comportamientos de riesgo y actitudes. Se realizaron análisis bivariados y análisis de varianza con ensayos post-hoc de Bonferroni. Resultados Homosexuales (92,3 %) y bisexuales (84,9 %) refirieron el uso de aplicaciones y tuvieron citas con pareja casual (p<0,05). Tinder fue la aplicación a la que el 93,58 % de los usuarios accedió. No hubo diferencias en la práctica sexual, sexo desprotegido y múltiples parejas sexuales. Información sobre sexo seguro y sobre infecciones de transmisión sexual por medio de las aplicaciones fue reportada por homosexuales (61,1 %) (p<0,05). Bisexuales (22,2 %) vivieron la educación sexual en los eventos científicos, y heterosexuales (38,2 %) recurrieron a sus amigos de la universidad (p<0,05). Homosexuales (88,9 %) accedieron al servicio del Centro de Testeo y de Consejo, y el 72,4 % realizó el testeo de infecciones sexualmente transmisibles después de la práctica sexual con pareja casual (p<0,05). Se observaron actitudes positivas hacia la salud sexual en los heterosexuales no usuarios de aplicaciones de citas. Conclusión La vulnerabilidad de los usuarios de aplicaciones de citas no estuvo asociada con la orientación sexual. Son necesarias intervenciones por medio de la educación sexual que estimulen el autoconocimiento y los riesgos de la práctica sexual desprotegida ante el acceso a las tecnologías para citas casuales.

Abstract Objective To analyze sex education, risk behaviors and attitudes of college students who use dating applications, considering their sexual orientation. Methods This is a quantitative, cross-sectional and descriptive study, with a non-probabilistic convenience sample, consisting of 359 college students from northern Brazil. A questionnaire was used with information on sociodemographic data, use of dating applications, sources of information on protected sex, risk behaviors and attitudes. Bivariate analyzes and analysis of variance with Bonferroni's post-hoc tests were performed. Results Homosexuals (92.3%) and bisexuals (84.9%) reported using applications and meeting with casual partners (p<0.05). Tinder was the application accessed by 93.58% of users. There was no difference for sexual practice, unprotected sex and multiple sexual partners. Information about protected sex and sexually transmitted infections through the applications was reported by homosexuals (61.1%) (p<0.05). Bisexuals (22.2%) experienced sex education in scientific events and heterosexuals (38.2%) turned to college friends (p<0.05). Homosexuals (88.9%) accessed the Testing and Counseling Center service and 72.4% were tested for sexually transmitted infections after having sex with a casual partner (p<0.05). Positive attitudes towards sexual health were observed in heterosexual non-dating application users. Conclusion Vulnerability of dating application users was not associated with sexual orientation. Interventions through sex education that stimulate self-knowledge and the risks of unprotected sexual practice are required in view of access to technologies for casual dates.

Automedicação entre estudantes de graduação do interior do Amazonas / Automedicación entre estudiantes universitarios del interior del estado de Amazonas / Self-medication among undergraduate students from the countryside of Amazonas

Resumo Objetivo Estimar a prevalência e fatores associados à automedicação entre estudantes de cursos de graduação do interior do Amazonas. Métodos Estudo transversal com 694 estudantes de uma universidade pública do interior do Amazonas, entre março a julho de 2018. Definiu-se automedicação como uso de, no mínimo, um medicamento sem prescrição. Estimaram-se Odds Ratio (OR) e Intervalos de Confiança de 95% (IC 95%) pela Regressão Logística. Resultados Dos 694 graduandos, 483 indicaram consumo medicamentoso. Destes, 80,1% referiram automedicação. Os analgésicos foram os mais utilizados (51,8%) e os motivos que mais levaram a se automedicarem foram os problemas álgicos (54,3%). As variáveis "ter filhos" (OR: 1,83; IC 95%: 1,06-3,16) e "ter a prática de indicar medicamentos para terceiros" (OR: 2,38; IC 95%: 1,47-3,86) permaneceram independentemente associadas à automedicação. Conclusão Observou-se alta prevalência da automedicação entre os estudantes, evidenciando a necessidade de discussão sobre o uso racional de medicamentos no ambiente universitário.

Resumen Objetivo Estimar la prevalencia y factores asociados con la automedicación entre estudiantes de cursos universitarios del interior del estado de Amazonas. Métodos Estudio transversal con 694 estudiantes de una universidad pública del interior del estado de Amazonas, entre marzo a julio de 2018. Se definió la automedicación como el uso de, como mínimo, un medicamento sin prescripción. Se estimaron Odds Ratio (OR) e Intervalos de Confianza del 95 % (IC 95 %) por Regresión Logística. Resultados De los 694 estudiantes universitarios, 483 indicaron un consumo medicamentoso. De estos, 80,1 % mencionaron automedicación. Los analgésicos fueron los más utilizados (51,8 %) y los motivos que más llevaron a la automedicación fueron los problemas álgicos (54,3 %). Las variables "tener hijos" (OR: 1,83; IC 95 %: 1,06-3,16) y "tener la práctica de indicar medicamentos a terceros" (OR: 2,38; IC 95 %: 1,47-3,86) permanecieron independientemente asociadas a la automedicación. Conclusión Se observó alta prevalencia de automedicación entre los estudiantes, evidenciando la necesidad de discusión sobre el uso racional de medicamentos en el ambiente universitario.

Abstract Objective To estimate the prevalence and factors associated with self-medication among undergraduate students in the countryside of Amazonas. Methods Cross-sectional study with a total of 694 students from a public university in the countryside of Amazonas, between March and July 2018. Self-medication was defined as the use of at least one medication without a prescription. Odds Ratio (OR) and 95% Confidence Intervals (95% CI) were estimated by Logistic Regression. Results Of the 694 undergraduate students, 483 indicated drug use. Of these, 80.1% reported self-medication. Analgesics were the most used (51.8%) and the reasons that most led to self-medicating were pain problems (54.3%). The variables "having children" (OR: 1.83; 95% CI: 1.06-3.16) and "having the practice of recommending medication to other people" (OR: 2.38; 95% CI: 1.47 -3.86) remained independently associated with self-medication. Conclusion There was a high prevalence of self-medication among students, highlighting the need for discussion about the rational use of medication in the university environment.

Development and Validation of a Questionnaire to Assess Creative Potential Traits.

The aim of the study was to develop an inventory to assess traits of creative potential and to analyze its psychometric properties. Three dimensions that could be associated with creative potential were proposed: willingness to transgress, willingness to take on challenges, and willingness to explore. For this purpose 551 participants were chosen to respond to an inventory composed of 12 items: Traits of Creative Potential Questionnaire, (TCPQ-12) and other tests to determine concurrent validity. The correlations between these instruments were significant. In addition, the instrument showed adequate internal consistency (Ω = 0.813) and the exploratory factor analysis yielded salient factors coincident with the proposed dimensions. The confirmatory factor analysis indicated an optimal fit (CFI = 0.984, TLI = 0.979, GFI = 0.963, RMSEA = 0.035). with composite reliability (CR) values > 0.70 in two factors and in one was slightly lower (CR = 0.684). The average variance extracted (AVE) was > 0.5 in two factors and in one < 0.5. The study data allow to highlight that the instrument presented here is a concise instrument with adequate psychometric properties.

Trajectories of maternal depressive symptoms and offspring's risk behavior in early adolescence: data from the 2004 Pelotas birth cohort study.

BACKGROUND: This longitudinal study explored the relationship between trajectories of maternal depressive symptoms and offspring's risk behavior in adolescence contributing to an extremely scarce literature about the impacts of maternal depression trajectories on offspring risk behaviors. METHODS: We included 3437 11-year-old adolescents from the 2004 Pelotas Birth Cohort Study. Trajectories of maternal depressive symptoms were constructed using Edinburgh Postnatal Depression Scale (EDPS) from age 3 months to 11 years. We identified five trajectories of maternal depressive symptoms: "low" "moderate low", "increasing", "decreasing", and "chronic high". The following adolescent outcomes were identified via self-report questionnaire and analyzed as binary outcome -yes/no: involvement in fights and alcohol use at age 11. We used logistic regression models to examine the effects of trajectories of maternal depressive symptoms on offspring's risk behavior adjusting for potential confounding variable. RESULTS: Alcohol use and/or abuse as well as involvement in fights during adolescence, were not significantly associated with any specific trajectory of maternal depressive symptoms neither in the crude nor in the adjusted analyses. CONCLUSION: Alcohol use and involvement in fights at age 11 were not associated with any specific trajectory of maternal depression.

Decision-Making Under Risk and Uncertainty by Substance Abusers and Healthy Controls.

Cognitive impairment characterized by high impulsivity and risk-taking has been correlated with substance-related disorders. However, it is unclear if the decision-making process is well known upon consideration of factors such as uncertainty environments, risk, and time manipulation in different decision-making procedures. The main objective of this study was to identify behavioral differences between substance abusers and healthy control participants in a behavioral test battery, including (1) two uncertainty decision-making tasks, the Balloon Analog Risk Task (BART) and the Iowa Gambling Task (IGT, trial 1-40); (2) three risk-taking tasks, the Columbia Card Task Hot version (CCT-hot), Columbia Card Task Cold version (CCT-cold), and the IGT (trial 41-100); and (3) an impulsivity task, the Delay Discounting task (DD). The second objective looked at how the six behavioral tests correlate. We worked with a sample of 54 adult participants (Substance abusers: n = 28; Healthy controls: n = 26). An anonymous survey website was created to execute all the cognitive tasks. The results showed no statistically significant differences between the groups in any of the tasks. However, the results showed an upward trend of impulsive (i.e., steeply discounting curve) and risk-taking behaviors (i.e., a low learning curve in IGT) in substance abuse participants. The factor analysis results showed four different main factors: (1) risk-taking task in the IGT (trial 40-100), (2) uncertainty task in BART, (3) impulsivity in DD, IGT (trial 1-40), and (4) deliberate process in the Columbia card task (cold and hot). We conclude that factors such as the uncertainty tasks in the BART and the first block of IGT trials, the risk cues in the CCT tasks (i.e., number of loss, number of gains, and loss cards), and the time to delivery in the DD task, can affect the complex decision-making process in both clinical and healthy groups.

Mexican descent college student risky sexual behaviors and alcohol use: The role of general and cultural based coping with discrimination.

OBJECTIVE: This study investigates cultural and general coping strategies as potential protective or risk factors to risky sexual behaviors (RSBs) and alcohol use in the face of discrimination for Mexican descent college students. Participants: Data collection was conducted from September 2016 to May 2017 and included 796 Mexican descent emerging adults. Methods: Linear regressions were conducted to test main and interaction effects of discrimination, and general and cultural coping strategies on RSBs and alcohol use issues. Results: Higher discrimination experiences were not associated with RSBs or alcohol use issues. Only ethnicity-based coping was found to be a significant moderator to the relationships between discrimination and the outcome variables of RSBs and alcohol use issues. Conclusions: This study has implications for the way mental health clinicians explore the intersection of ethnic identity and coping as a means of understanding the relationship among discrimination, RSBs, and alcohol use issues.

La vulnerabilidad y el riesgo: reflexiones a propósito de la pandemia del covid-19 / Vulnerabilidade e risco: reflexões sobre a pandemia de Covid-19 / Vulnerability and risk: reflections on the COVID-19 pandemic

RESUMEN A finales de diciembre 2019 se identificó el virus SARS-COV-2 como responsable de la pandemia de Covid-19. La rápida expansión de la transmisión puso al descubierto fallas estructurales de las sociedades modernas y de los sistemas de salud para prevenir y contener una amenaza sanitaria. La discusión científica se ha concentrado en la búsqueda de una vacuna, pero menos en comprender la respuesta social ante la amenaza globalizada actual y el temor a los rebrotes. En este ensayo reflexionamos, desde las ciencias sociales, sobre la importancia de vincular tres conceptos: vulnerabilidad-percepción-riesgo. Esto es necesario para desarrollar estrategias preventivas adecuadas a las circunstancias poblacionales, especialmente con la población más vulnerable, a favor de la equidad en salud.

RESUMO No final de dezembro de 2019, o vírus SARS-COV-2 foi identificado como responsável pela pandemia de Covid-19. A rápida propagação da transmissão expôs falhas estruturais das sociedades modernas e dos sistemas de saúde na prevenção e contenção de uma ameaça sanitária. A discussão científica tem se concentrado na busca por uma vacina, mas menos na compreensão da resposta social à atual ameaça global e ao medo de novos surtos. Neste ensaio refletimos, a partir das ciências sociais, sobre a importância de associar três conceitos: vulnerabilidade-percepção-risco. Isso é necessário para desenvolver estratégias preventivas adequadas às circunstâncias da população, principalmente junto à população mais vulnerável, em prol da equidade na saúde.

ABSTRACT At the end of December 2019, SARS-COV-2 virus was identified as responsible for the COVID-19 pandemic. The rapid spread of transmission exposed structural failures of modern societies and of the health systems in preventing and containing a health threat. Scientific discussion has focused on the search for a vaccine, but less on understanding the social response to the current global threat and fear of outbreaks. In this essay, we reflect, based on the social sciences, on the importance of linking three concepts: vulnerability-perception-risk. This is necessary to develop preventive strategies appropriate to population circumstances, especially with the most vulnerable population, in favor of health equity.