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1.
Magn Reson Imaging ; 2024 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-38971265

RESUMO

Low field MRI is safer and more cost effective than the high field MRI. One of the inherent problems of low field MRI is its low signal-to-noise ratio or sensitivity. In this work, we introduce a multimodal surface coil technique for signal excitation and reception to improve the RF magnetic field (B1) efficiency and potentially improve MR sensitivity. The proposed multimodal surface coil consists of multiple identical resonators that are electromagnetically coupled to form a multimodal resonator. The field distribution of its lowest frequency mode is suitable for MR imaging applications. The prototype multimodal surface coils are built, and the performance is investigated and validated through numerical simulation, standard RF measurements and tests, and comparison with the conventional surface coil at low fields. Our results show that the B1 efficiency of the multimodal surface coil outperforms that of the conventional surface coil which is known to offer the highest B1 efficiency among all coil categories, i.e., volume coil, half-volume coil and surface coil. In addition, in low-field MRI, the required low-frequency coils often use large value capacitance to achieve the low resonant frequency which makes frequency tuning difficult. The proposed multimodal surface coil can be conveniently tuned to the required low frequency for low-field MRI with significantly reduced capacitance value, demonstrating excellent low-frequency operation capability over the conventional surface coil.

2.
J Magn Reson Imaging ; 60(2): 777-788, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38305462

RESUMO

BACKGROUND: The minimum admissible detuning efficiency (DE) of a receive coil is an essential parameter for coil designers. A receive coil with inefficient detuning leads to inhomogeneous B1 during excitation. Previously proposed criteria for quantifying the DE rely on indirect measurements and are difficult to implement. PURPOSE: To present an alternative method to quantify the DE of receive-only surface coils. STUDY TYPE: Theoretical study supported by simulations and phantom experiments. PHANTOMS: Uniform spherical (100 mm diameter) and cylindrical (66 mm diameter) phantoms. FIELD STRENGTH/SEQUENCE: Dual repetition time B1 mapping sequence at 1.5T, and Bloch-Siegert shift B1 mapping sequence at 3.0T. ASSESSMENT: One non-planar (80 × 43 mm2) and two planar (40 and 57 mm diameter) surface coils were built. Theoretical analysis was performed to determine the minimum DE required to avoid B1 distortions. Experimental B1 maps were acquired for the non-planar and planar surface coils at both 1.5T and 3.0T and visually compared with simulated B1 maps to assess the validity of the theoretical analysis. STATISTICAL TESTS: None. RESULTS: Based on the theoretical analysis, the proposed minimum admissible DE, defined as DEthr = 20 Log (Q) + 13 dB, depended only on the quality factor (Q) of the coil and was independent of coil area and field strength. Simulations and phantom experiments showed that when the DE was higher than this minimum threshold level, the B1 field generated by the transmission coil was not modified by the receive coil. DATA CONCLUSION: The proposed criterion for assessing the DE is simple to measure, and does not depend on the area of the coil or on the magnetic field strength, up to 3T. Experimental and simulated B1 maps confirmed that detuning efficiencies above the theoretically derived minimal admissible DE resulted in a non-distorted B1 field. EVIDENCE LEVEL: 2 TECHNICAL EFFICACY: Stage 1.


Assuntos
Simulação por Computador , Desenho de Equipamento , Imageamento por Ressonância Magnética , Imagens de Fantasmas , Imageamento por Ressonância Magnética/instrumentação , Reprodutibilidade dos Testes , Humanos , Processamento de Imagem Assistida por Computador , Algoritmos , Modelos Teóricos
3.
NMR Biomed ; 37(8): e5120, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38404058

RESUMO

Concentrations of the key metabolites of hepatic energy metabolism, adenosine triphosphate (ATP) and inorganic phosphate (Pi), can be altered in metabolic disorders such as diabetes mellitus. 31Phosphorus (31P)-magnetic resonance spectroscopy (MRS) is used to noninvasively measure hepatic metabolites, but measuring their absolute molar concentrations remains challenging. This study employed a 31P-MRS method based on the phantom replacement technique for quantifying hepatic 31P-metabolites on a 3-T clinical scanner. Two surface coils with different size and geometry were used to check for consistency in terms of repeatability and reproducibility and absolute concentrations of metabolites. Day-to-day (n = 8) and intra-day (n = 6) reproducibility was tested in healthy volunteers. In the day-to-day study, mean absolute concentrations of γ-ATP and Pi were 2.32 ± 0.24 and 1.73 ± 0.26 mM (coefficient of variation [CV]: 7.3% and 8.8%) for the single loop, and 2.32 ± 0.42 and 1.73 ± 0.27 mM (CVs 6.7% and 10.6%) for the quadrature coil, respectively. The intra-day study reproducibility using the quadrature coil yielded CVs of 4.7% and 6.8% for γ-ATP and Pi without repositioning, and 6.3% and 7.1% with full repositioning of the volunteer. The results of the day-to-day data did not differ between coils and visits. Both coils robustly yielded similar results for absolute concentrations of hepatic 31P-metabolites. The current method, applied with two different surface coils, can be readily utilized in long-term and interventional studies. In comparison with the single loop coil, the quadrature coil also allows measurements at a greater distance between the coil and liver, which is relevant for studying people with obesity.


Assuntos
Trifosfato de Adenosina , Fígado , Espectroscopia de Ressonância Magnética , Fosfatos , Humanos , Trifosfato de Adenosina/metabolismo , Trifosfato de Adenosina/análise , Fígado/metabolismo , Fígado/diagnóstico por imagem , Reprodutibilidade dos Testes , Fosfatos/metabolismo , Espectroscopia de Ressonância Magnética/instrumentação , Masculino , Adulto , Feminino , Isótopos de Fósforo , Imagens de Fantasmas
4.
Magn Reson Med ; 89(6): 2204-2216, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36669882

RESUMO

PURPOSE: To expand on the previously developed B 1 + $$ {\mathrm{B}}_1^{+} $$ -encoding technique, frequency-modulated Rabi-encoded echoes (FREE), to perform accelerated image acquisition by collecting multiple lines of k-space in an echo train. METHODS: FREE uses adiabatic full-passage pulses and a spatially varying RF field to encode unique spatial information without the use of traditional B0 gradients. The original implementation relied on acquiring single lines of k-space, leading to long acquisitions. In this work, an acceleration scheme is presented in which multiple echoes are acquired in a single shot, analogous to conventional fast spin-echo sequences. Theoretical analysis and computer simulations investigated the feasibility of this approach and presented a framework to analyze important imaging parameters of FREE-based sequences. Experimentally, the multi-echo approach was compared with conventional phase-encoded images of the human visual cortex using a simple surface transceiver coil. Finally, different contrasts demonstrated the clinical versatility of the new accelerated sequence. RESULTS: Images were acquired with an acceleration factor of 3.9, compared with the previous implementation of FREE, without exceeding specific absorption rate limits. Different contrasts can easily be acquired without major modifications, including inversion recovery-type images. CONCLUSION: FREE initially illustrated the feasibility of performing slice-selective 2D imaging of the human brain without the need for a B0 gradient along the y-direction. The multi-echo version maintains the advantages that B 1 + $$ {\mathrm{B}}_1^{+} $$ encoding provides but represents an important step toward improving the clinical feasibility of such sequences. Additional acceleration and more advanced reconstruction techniques could further improve the clinical viability of FREE-based techniques.


Assuntos
Encéfalo , Imageamento por Ressonância Magnética , Humanos , Imageamento por Ressonância Magnética/métodos , Encéfalo/diagnóstico por imagem , Cabeça , Simulação por Computador , Aceleração , Processamento de Imagem Assistida por Computador/métodos , Imagens de Fantasmas
5.
Magn Reson Med ; 89(5): 2100-2108, 2023 05.
Artigo em Inglês | MEDLINE | ID: mdl-36517956

RESUMO

PURPOSE: To correct image distortions that result from nonlinear spatial variation in the transmit RF field amplitude ( B 1 + $$ {B}_1^{+} $$ ) when performing spatial encoding with the method called frequency-modulated Rabi encoded echoes (FREE). THEORY AND METHODS: An algorithm developed to correct image distortion resulting from the use of nonlinear static field (B0 ) gradients in standard MRI is adapted herein to correct image distortion arising from a nonlinear B 1 + $$ {B}_1^{+} $$ -gradient field in FREE. From a B 1 + $$ {B}_1^{+} $$ -map, the algorithm performs linear interpolation and intensity scaling to correct the image. The quality of the distortion correction is evaluated in 1.5T images of a grid phantom and human occipital lobe. RESULTS: An expanded theoretical description of FREE revealed the symmetry between this B 1 + $$ {B}_1^{+} $$ -gradient field spatial-encoding and standard B0 -gradient field spatial-encoding. The adapted distortion-correction algorithm substantially reduced image distortions arising in the spatial dimension that was encoded by the nonlinear B 1 + $$ {B}_1^{+} $$ gradient of a circular surface coil. CONCLUSION: Image processing based on straightforward linear interpolation and intensity scaling, as previously applied in conventional MRI, can effectively reduce distortions in FREE images acquired with nonlinear B 1 + $$ {B}_1^{+} $$ -gradient fields.


Assuntos
Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética , Humanos , Imageamento por Ressonância Magnética/métodos , Processamento de Imagem Assistida por Computador/métodos , Algoritmos , Imagens de Fantasmas
6.
Chinese Journal of Radiology ; (12): 41-47, 2023.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-992939

RESUMO

Objective:To investigate the value of the 8-channel eye surface phased array coil in improving image quality and demonstrating ocular masses on 3.0 T MR scanner.Methods:From July 2018 to January 2020, the data of orbital MRI in 692 patients with ocular masses on 6 medical centers were prospectively collected. The patients were simple randomly assigned into 8-channel eye surface phased array coil group (413 patients) or 8-channel head phased array coil group (279 patients), with the same MRI sequences. The signal to noise ratio (SNR) and contrast to noise ratio (CNR) were calculated in orbital anatomy structures and masses (eyelid mass, intraocular mass, lacrimal mass and orbital mass). The image quality scores including motion artifact, mass margin, the relationship between the mass and adjacent structures, and overall image quality were recorded. The differences of image quality between the two groups were compared by two independent sample t-test or Wilcoxon rank test. Results:The SNR and CNR were higher in eye surface coil group than those in head coil group ( P<0.05). The scores of ocular movement artifacts were higher in head coil group than those in surface coil group ( P<0.05). The scores of intraocular mass margin, the relationship between the mass and adjacent structures, and overall image quality were higher in surface coil group than those in head coil group ( P<0.001). There were no significant differences in mass margin, the relationship between the mass and adjacent structures, and overall image quality scores of eyelid, lacrimal gland, and orbital mass between the two groups ( P>0.05). Conclusion:3.0 T MR scanner combined with the 8-channel eye surface phased array coil can improve the SNR and CNR of orbital MR images, the demonstration of the intraocular mass margin and the relationship between the mass and adjacent structures.

7.
J Magn Reson ; 339: 107215, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35421711

RESUMO

Very-low field magnetic resonance imaging (VLF-MRI, B0 < 0.1T) has an essential application in medical imaging diagnosis because of its light weight and low cost. For single-channel RF coil VLF-MRI system, a planar spiral LC-resonator placed on the surface of samples was designed to improve the local SNR. First, an equivalent circuit model was established to evaluate the boosting effects on radiofrequency (RF) magnetic field and SNR. Second, the relationship between the resonant capacitance and the transmission coefficient was deduced according to the circuit model, and the appropriate resonant capacitance was obtained. Then, the influence of the diameter and the number of turns of the LC-resonator on the SNR is considered, and the structure of the LC-resonator was optimized to maximize the SNR. Finally, a phantom MRI experiment was carried out with our home-built 54.6 mT MRI system to compare the SNR of the experiment with the calculation, the SNR enhancement trend of the two was consistent. Additional experiments were conducted using orange and chicken leg to demonstrate the SNR enhancement abilities of the LC-resonator. The enhancement of SNR reached up to 1.8-fold and 2.2-fold depending on the distance between the sample and LC-resonator. For comparison, we conducted imaging experiments on surface receiving coil with the same parameters, and the results show that the SNR of the LC resonator is comparable to that of the surface coil. The reported LC-resonator provide a low-cost local enhancement method for VLF-MRI.


Assuntos
Aumento da Imagem , Imageamento por Ressonância Magnética , Desenho de Equipamento , Imageamento por Ressonância Magnética/métodos , Imagens de Fantasmas , Razão Sinal-Ruído
8.
Magn Reson Med ; 87(2): 674-685, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34498768

RESUMO

PURPOSE: Reduce expense and increase accessibility of MRI by eliminating pulsed field (B0 ) gradient hardware. METHODS: A radiofrequency imaging method is described that enables spatial encoding without B0 gradients. This method, herein referred to as frequency-modulated Rabi-encoded echoes (FREE), utilizes adiabatic full passage pulses and a gradient in the RF field (B1 ) to produce spatially dependent phase modulation, equivalent to conventional phase encoding. In this work, Cartesian phase encoding was accomplished using FREE in a multi-shot double spin-echo sequence. Theoretical analysis and computer simulations investigated the influence of resonance offset and B1 -gradient steepness and magnitude on reconstruction quality, which limit other radiofrequency imaging methodologies. Experimentally, FREE was compared to conventional phase-encoded MRI on human visual cortex using a simple surface transceiver coil. RESULTS: Image distortions occurred in FREE when using nonlinear B1 fields where the phase dependence becomes nonlinear, but with minimal change in signal intensity. Resonance offset effects were minimal for Larmor frequencies within the adiabatic full-passage pulse bandwidth. CONCLUSION: For the first time, FREE enabled slice-selective 2D imaging of the human brain without a B0 gradient in the y-direction. FREE achieved high resolution in regions where the B1 gradient was steepest, whereas images were distorted in regions where nonlinearity in the B1 gradient was significant. Given that FREE experiences no significant signal loss due to B1 nonlinearities and resonance offset, image distortions shown in this work might be corrected in the future based on B1 and B0 maps.


Assuntos
Imageamento por Ressonância Magnética , Ondas de Rádio , Encéfalo/diagnóstico por imagem , Simulação por Computador , Humanos , Imagens de Fantasmas
9.
Technol Health Care ; 30(4): 827-838, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34657859

RESUMO

BACKGROUND: Addressing intensity inhomogeneity is critical in magnetic resonance imaging (MRI) because associated errors can adversely affect post-processing and quantitative analysis of images (i.e., segmentation, registration, etc.), as well as the accuracy of clinical diagnosis. Although several prior methods have been proposed to eliminate or correct intensity inhomogeneity, some significant disadvantages have remained, including alteration of tissue contrast, poor reliability and robustness of algorithms, and prolonged acquisition time. OBJECTIVE: In this study, we propose an intensity inhomogeneity correction method based on volume and surface coils simultaneous reception (VSSR). METHODS: The VSSR method comprises of two major steps: 1) simultaneous image acquisition from both volume and surface coils and 2) denoising of volume coil images and polynomial surface fitting of bias field. Extensive in vivo experiments were performed considering various anatomical structures, acquisition sequences, imaging resolutions, and orientations. In terms of correction performance, the proposed VSSR method was comparatively evaluated against several popular methods, including multiplicative intrinsic component optimization and improved nonparametric nonuniform intensity normalization bias correction methods. RESULTS: Experimental results show that VSSR is more robust and reliable and does not require prolonged acquisition time with the volume coil. CONCLUSION: The VSSR may be considered suitable for general implementation.


Assuntos
Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética , Algoritmos , Encéfalo , Humanos , Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Reprodutibilidade dos Testes
10.
J Magn Reson ; 333: 107100, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34801823

RESUMO

Meander-line, or zig-zag, MRI surface coils theoretically promise spatially uniform fields with optimal field localization close to the coil. In reality, they suffer poorer than expected field localizations and acquired images are often highly inhomogeneous, plagued by repeating stripe-like signal-loss artifacts. We show that both these detrimental effects arise from coil design based on the same invalid approximation in the underlying theory. Here, the conventional approximation is corrected, yielding a modified coil design that validates the new theory by rectifying the above problems. Specifically, an easily implementable coil correction, which amounts to the addition of a single extra turn of wire, is introduced and shown to increase signal uniformity by an order of magnitude, eliminate image artifacts, and reduce unwanted signal interference from deeper within the sample by tightening the coil field localization to close to the coil, as intended for zig-zag designs. With independent optimization of coil size and imaging depth possible, such corrected meander-lines surface coils may be well suited for large area, near-surface imaging and spectroscopy applications.

11.
J Magn Reson ; 323: 106890, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33352434

RESUMO

This article describes the development of a two-channel surface coil array for Overhauser-enhanced magnetic resonance imaging (OMRI) with the aim of extending the visualization area. The surface coil array consists of two independent surface coil resonators and PIN-diode switches. We utilized the PIN-diode switch to decouple the surface coils. OMRI measurement using a surface coil array was sequentially performed by switching the channels. To evaluate the effectiveness of the surface coil array, we demonstrated OMRI measurements using a phantom filled with nitroxide solution. In addition, in vivo OMRI imaging with a mouse was performed to demonstrate the applicability of our surface coil array to in vivo measurements. As a result, the visualization area obtained with our surface coil array was extended approximately 2-fold compared to the conventional single surface coil. Furthermore, we showed that in vivo imaging with the surface coil array was possible. These results indicate that the surface coil array could enhance the applicability of OMRI imaging.


Assuntos
Espectroscopia de Ressonância de Spin Eletrônica/instrumentação , Imageamento por Ressonância Magnética/instrumentação , Animais , Desenho de Equipamento , Feminino , Camundongos , Imagens de Fantasmas
12.
Chinese Journal of Radiology ; (12): 710-715, 2021.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-910229

RESUMO

Objective:To explore the value of multi-parametric MRI for thyroid gland in differentiating benign and malignant thyroid nodules.Methods:From December 2018 to May 2020, 78 patients with 91 post-surgically pathologically confirmed thyroid nodules were enrolled in Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. For each patient, the following MRI findings were obtained including the nodules′ location, size, shape, margin, signal intensity, cystic change, degree and pattern of contrast enhancement, involvement of surrounding structure, and ADC values. The time-intensity curve (TIC) were plotted and subtyped based on dynamic contrast enhancement MRI. The MRI findings between the benign and malignant thyroid nodules were compared using Mann-Whitney U test, χ 2 test or Fisher exact test. Multiple logistic regression analysis was used to select independent predictive variables and build a combined model, and the ROC curve was used to evaluate the diagnostic performance of each MRI finding and the combined model. Results:Between the benign and malignant thyroid nodules, the significant differences were found in size, shape, margin, presence of cystic changes, T 1WI signal intensity, ADC value, enhancement homogeneity, TIC subtypes and presence of thyroid capsule involvement ( P<0.05). Multivariate logistic analysis showed that ill-defined margin (OR=77.61), no presence of cystic changes (OR=36.11) and difference between TIC subtypes (OR=83.41) were independent predictive variables, and the area under the ROC curve (AUC) was 0.879, 0.788, and 0.751, respectively. The AUC, sensitivity and specificity of the combined model were 0.977, 0.986, and 0.904, respectively. Conclusions:Thyroid multi-parametric MRI derived findings can be used for the differential diagnosis of benign and malignant nodules. Combined with the independent risk factors with ill-defined margin, no presence of cystic changes, TIC of type plateau or washout, the diagnostic model has a higher diagnostic efficiency.

13.
Acta Derm Venereol ; 100(18): adv00317, 2020 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-32945342

RESUMO

Hidradenitis suppurativa has a substantial negative effect on quality of life of affected persons. Diagnosis is based mainly on clinical examination. However, physi-cal examination alone might underestimate disease severity compared with imaging modalities. We report here the application of non-contrast-enhanced 3-Tesla magnetic resonance imaging using surface-coil and sonography for assessment of hidradenitis suppurativa lesions based on topographic assessment of skin lesions. In addition, we review the literature regarding the application of ultrasound and magnetic resonance imaging in hidradenitis suppurativa.


Assuntos
Hidradenite Supurativa , Hidradenite Supurativa/diagnóstico por imagem , Humanos , Imageamento por Ressonância Magnética , Qualidade de Vida , Índice de Gravidade de Doença , Ultrassonografia
14.
J Magn Reson ; 311: 106681, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31923765

RESUMO

A receive-only surface coil array for 3 Tesla integrating a high-permittivity material (HPM) with a relative permittivity of 660 was designed and constructed and subsequently its performance was evaluated and compared in terms of transmit field efficiency and specific absorption ratio (SAR) during transmission, and signal-to-noise ratio during reception, with a conventional identically-sized surface coil array. Finite-difference time-domain simulations, bench measurements and in-vivo neck imaging on three healthy volunteers were performed using a three-element surface coil array with integrated HPMs placed around the larynx. Simulation results show an increase in local transmit efficiency of the body coil of ~10-15% arising from the presence of the HPM. The receiver efficiency also increased by approximately 15% close to the surface. Phantom experiments confirmed these results. In-vivo scans using identical transmit power resulted in SNR gains throughout the laryngeal area when compared with the conventional surface coil array. In particular specifically around the carotid arteries an average SNR gain of 52% was measured averaged over the three subjects, while in the spine an average of 20% SNR gain was obtained.


Assuntos
Imageamento por Ressonância Magnética/instrumentação , Imageamento por Ressonância Magnética/métodos , Pescoço/diagnóstico por imagem , Algoritmos , Artérias Carótidas/diagnóstico por imagem , Simulação por Computador , Campos Eletromagnéticos , Desenho de Equipamento , Análise de Elementos Finitos , Voluntários Saudáveis , Humanos , Aumento da Imagem , Laringe/diagnóstico por imagem , Imagens de Fantasmas , Razão Sinal-Ruído , Coluna Vertebral/diagnóstico por imagem
15.
Abdom Radiol (NY) ; 45(7): 2213-2224, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-31552463

RESUMO

Nonobstructive azoospermia (NOA) can be caused by various diseases, including congenital disorders, endocrine disorders, infections, tumor or tumor-like diseases, vascular diseases, etc. Diagnosis of the underlying cause of NOA is complicated and challenging. In this study, we introduce an MR examination protocol for the etiological diagnosis of NOA, and demonstrate a series of NOA patients with different causes and imaging findings. Except for lesions of testes, the patients may also combine abnormalities of adrenal glands and central nervous system. In such cases, the patients could benefit from additional abdominal and intracranial scans.


Assuntos
Azoospermia , Abdome , Azoospermia/diagnóstico por imagem , Humanos , Imageamento por Ressonância Magnética , Masculino , Pelve , Testículo
16.
Int J Cardiovasc Imaging ; 36(3): 521-532, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31728679

RESUMO

In this study, we sought to investigate the impact of baseline calibration, which is used in quantitative cardiac MRI perfusion analysis to correct for surface coil inhomogeneity and noise, on myocardial perfusion reserve index (MPRI) and its contribution to previously reported paradoxical low MPRI < 1.0 in patients with unobstructed coronary arteries. Semiquantitative perfusion analysis was performed in 20 patients with unobstructed coronary arteries undergoing stress/rest perfusion CMR and in ten patients undergoing paired rest perfusion CMR. The following baseline calibration settings were compared: (1) baseline division, (2) baseline subtraction and (3) no baseline calibration. In uncalibrated analysis, we observed ~ 20% segmental dispersion of signal intensity (SI)-over-time curves. Both baseline subtraction and baseline division reduced relative dispersion of t0-SI (p < 0.001), but only baseline division corrected for dispersion of peak-SI and maximum upslope also (p < 0.001). In the assessment of perfusion indices, however, baseline division resulted in paradoxical low MPRI (1.01 ± 0.23 vs. 1.63 ± 0.38, p < 0.001) and rest perfusion index (RPI 0.54 ± 0.07 vs. 0.94 ± 0.12, p < 0.001), respectively. This was due to a reversed ratio of blood-pool and myocardial baseline-SI before the second perfusion study caused by circulating contrast agent from the first injection. In conclusion, baseline division reliably corrects for inhomogeneity of the surface coil sensitivity profile facilitating comparisons of regional myocardial perfusion during hyperemia or at rest. However, in the assessment of MPRI, baseline division can lead to paradoxical low results (even MPRI < 1.0 in patients with unobstructed coronary arteries) potentially mimicking severely impaired perfusion reserve. Thus, in the assessment of MPRI we propose to waive baseline calibration.


Assuntos
Adenosina/administração & dosagem , Angina Pectoris/diagnóstico por imagem , Imagem Cinética por Ressonância Magnética , Imagem de Perfusão do Miocárdio/métodos , Miocardite/diagnóstico por imagem , Vasodilatadores/administração & dosagem , Adulto , Idoso , Angina Pectoris/fisiopatologia , Calibragem , Circulação Coronária , Feminino , Humanos , Imagem Cinética por Ressonância Magnética/normas , Masculino , Pessoa de Meia-Idade , Imagem de Perfusão do Miocárdio/normas , Miocardite/fisiopatologia , Valor Preditivo dos Testes , Estudos Prospectivos , Reprodutibilidade dos Testes , Estudos Retrospectivos , Função Ventricular Esquerda
17.
J Magn Reson ; 309: 106626, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31678914

RESUMO

This study shows how a copper plate could be used for frequency tuning of surface wired and wireless MRI coils. For this purpose, it is proposed to place the copper plate directly on their conducting circuit. This leads to increase in the resonance frequency of coils. The effect is most perceptible if the copper plate is comparable in size to the conducting circuit of radiofrequency (RF) coil. The experimental work was performed on a 7.05 T MR scanner using surface MRI coils operating on different resonance frequencies: 1H (300 MHz), 31P (121 MHz), 23Na (79 MHz), 13C (75 MHz). Application of copper plate for frequency tuning of wireless multi-turn multi-gap transmission line resonator (MTMG-TLR) was considered for the first time. The proposed method can be claimed if the nominal variable inductance or capacitance is not enough for tuning the resonance frequency of the MRI coil to a higher frequency range.

18.
Quant Imaging Med Surg ; 9(6): 985-999, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31367553

RESUMO

BACKGROUND: The aim of this study is to validate and evaluate the reproducibility of a new setup for the quantification of the tissue sodium concentration (TSC) in the human upper leg muscles with sodium MRI at 3 Tesla. This setup is making use of an emit and receive single loop surface coil together with a set of square, symmetrically arranged reference phantoms. As a second aim, the performances of two MRI protocols for the TSC quantification in the upper leg muscles are compared: one using an ultra-short echo time (UTE) 3-dimensional radial sequence (UTE-protocol), and the other one using standard gradient echo sequence (GRE-protocol). METHODS: A validation test of the quantification of sodium concentration is performed in phantoms. The bias of the method is estimated and compared between both protocols. The reproducibility of TSC quantification is assessed in phantoms by the coefficient of variation (CV) and compared between both protocols. The reproducibility is also assessed in 11 health volunteers. Signal to noise ratio (SNR) maps are acquired in phantoms with both protocols in order to compare the resulting SNR. RESULTS: The apparatus and post processing were successfully implemented. The bias of the method was smaller than 10% in phantoms (excepted for Na concentration of 10 mmol/L when using the GRE protocol). The reproducibility of the method using symmetrically arranged phantoms was high in phantoms and humans (CV <5%). The GRE-protocol leads to a better SNR than the UTE-protocol in 2D images. CONCLUSIONS: The use of symmetrically arranged reference phantoms lead to reproducible results in phantoms and humans. Sodium imaging in the human upper leg with a single loop surface coil should be performed with a standard 2-dimensional GRE protocol if an optimal SNR is needed. However, the quantification of the fast and slow decay time constants of the sodium signal, which plays a role in the TSC quantification, still has to be done with a UTE sequence. Moreover, the quantification of sodium concentration is more accurate with the UTE protocol for small sodium concentrations (<20 mmol).

19.
Vet Ophthalmol ; 22(5): 703-709, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30977286

RESUMO

A 3-year-old French bulldog was presented to the ophthalmology service of the Vetsuisse Faculty, University of Zurich with a 3-day history of conjunctival swelling of the left eye (OS). Ophthalmologic examination revealed a moderate conjunctival hyperemia and chemosis. A migrating foreign body having entered the conjunctival fornix behind the nictitating membrane was suspected. Within the first 24 hours of medical management, OS developed a panuveitis and a scleral perforation was highly suspected. Ocular and orbital ultrasound as well as conventional magnetic resonance imaging (MRI) examinations failed to confirm the presence of a perforating foreign body. A High-Resolution MRI (HR-MRI) using a microscopy coil was then performed with findings consistent with a perforating and migrating foreign body. A grass awn of 12 mm length was surgically retrieved "ab externo" from its' point of entry into the sclera. To the best of our knowledge, HR-MRI has not yet been used to examine canine eyes. This case report supports the idea that orbital imaging can be greatly enhanced with the introduction of HR-MRI using microscopy coils with clinically relevant implications.


Assuntos
Túnica Conjuntiva , Doenças do Cão/patologia , Corpos Estranhos/veterinária , Imageamento por Ressonância Magnética/veterinária , Esclera , Animais , Túnica Conjuntiva/diagnóstico por imagem , Túnica Conjuntiva/cirurgia , Doenças do Cão/cirurgia , Cães , Feminino , Corpos Estranhos/diagnóstico por imagem , Corpos Estranhos/cirurgia , Esclera/diagnóstico por imagem , Esclera/cirurgia
20.
Cranio ; 37(2): 121-128, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29037113

RESUMO

OBJECTIVE: To report the number and frequency of incidental findings (IFs) detected during magnetic resonance (MR) imaging screening of the temporomandibular joint (TMJ) and to define related diseases. METHODS: Bilateral TMJ MR images in the sagittal and coronal sections, from 518 patients with TMJ symptoms were evaluated retrospectively. Patients who were diagnosed with IFs were sent for consultation and clarification of the findings. Patient age, gender, IFs, locations, and diseases were classified and noted.  Results: Seventy-eight (15%) patients were diagnosed with 117 IFs. Of them, 43 were diagnosed with a single IF, and 35 were diagnosed with more than one IF. The most frequent locations were paranasal sinuses and mastoid air cells. The most frequent diseases were inflammatory and cystic lesions.  Discussion: While examining TMJ MR images, it is important to check for evidence of IFs or pathologies that may have mimicked signs and symptoms of TMJ disorders.


Assuntos
Imagem de Difusão por Ressonância Magnética , Achados Incidentais , Articulação Temporomandibular/diagnóstico por imagem , Adulto , Idoso , Dissecação da Artéria Carótida Interna/diagnóstico por imagem , Cisticercose/diagnóstico por imagem , Cistos/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Hemangiopericitoma/diagnóstico por imagem , Humanos , Masculino , Músculo Masseter/diagnóstico por imagem , Sinusite Maxilar/diagnóstico por imagem , Pessoa de Meia-Idade , Doenças Negligenciadas/diagnóstico por imagem , Prevalência , Estudos Retrospectivos , Transtornos da Articulação Temporomandibular/diagnóstico por imagem
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