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Electrophoresis ; 40(18-19): 2256-2262, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30793781

RESUMO

1-propanol is a primary alcohol extensively used in the pharmaceutical, chemical, and food industries. It has been also found as a contaminant in the atmosphere and is considered a model compound to mimic the behavior and fate of aliphatic alcohols exposed to environmental conditions. In order to understand that role of relevant variables, this paper presents results obtained with a simple experimental set-up to investigate the reactivity of 1-propanol under mild oxidizing conditions. Coupling this system with CE-C4 D allowed the quantification of the carboxylic acids formed. For the described experiments, aqueous solutions of 1-propanol were placed inside a photoreactor and oxidized upon the addition of TiO2 and/or H2 O2 . According to the described results, the addition of H2 O2 (0.1% w/w) was the most significant variable, roughly tripled the amount of carboxylic acids generated and led to the conversion of up to 70% of the initially available 1-propanol (1 mmol/L). More importantly, the reaction yielded the formation (within 10 min) of propionate (50 µmol/L), acetate (400 µmol/L), formate (50 µmol/L), and malonate (200 µmol/L). The latter is critically important because it represents the first example of the photochemical oxidation of both terminal carbons of the C3 -chain of 1-propanol under mild conditions, and opens new avenues for the production of this important chemical building block.


Assuntos
1-Propanol , Peróxido de Hidrogênio , Fotólise , 1-Propanol/análise , 1-Propanol/química , 1-Propanol/efeitos da radiação , Condutividade Elétrica , Eletroforese Capilar , Malonatos/análise , Malonatos/química , Oxirredução , Fotólise/efeitos dos fármacos , Fotólise/efeitos da radiação , Raios Ultravioleta
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